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FR2742754B1 - Procede de preparation de taxoides - Google Patents

Procede de preparation de taxoides

Info

Publication number
FR2742754B1
FR2742754B1 FR9515381A FR9515381A FR2742754B1 FR 2742754 B1 FR2742754 B1 FR 2742754B1 FR 9515381 A FR9515381 A FR 9515381A FR 9515381 A FR9515381 A FR 9515381A FR 2742754 B1 FR2742754 B1 FR 2742754B1
Authority
FR
France
Prior art keywords
taxoids
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR9515381A
Other languages
English (en)
Other versions
FR2742754A1 (fr
Inventor
Herve Bouchard
Jean Dominique Bourzat
Alain Commercon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Rhone Poulenc Rorer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer SA filed Critical Rhone Poulenc Rorer SA
Priority to FR9515381A priority Critical patent/FR2742754B1/fr
Priority to MA24180A priority patent/MA23823A1/fr
Priority to PE1996000181A priority patent/PE51097A1/es
Priority to IL11763696A priority patent/IL117636A/en
Priority to IL15937896A priority patent/IL159378A/xx
Priority to EE9700315A priority patent/EE03608B1/xx
Priority to CA002214319A priority patent/CA2214319C/fr
Priority to EP96909193A priority patent/EP0817780B1/fr
Priority to RO97-01794A priority patent/RO115878B1/ro
Priority to EE9700323A priority patent/EE03609B1/xx
Priority to DE69604653T priority patent/DE69604653T2/de
Priority to RO97-01793A priority patent/RO115877B1/ro
Priority to SI9630132T priority patent/SI0817779T1/xx
Priority to ES96909193T priority patent/ES2140075T3/es
Priority to CZ19973030A priority patent/CZ287326B6/cs
Priority to AU52781/96A priority patent/AU703278B2/en
Priority to HU9801201A priority patent/HU223666B1/hu
Priority to NZ304900A priority patent/NZ304900A/en
Priority to AT96909193T priority patent/ATE185562T1/de
Priority to NZ304901A priority patent/NZ304901A/xx
Priority to BR9607930A priority patent/BR9607930A/pt
Priority to GEAP19963956A priority patent/GEP20002188B/en
Priority to KR1019970706691A priority patent/KR100297196B1/ko
Priority to EA199700269A priority patent/EA000567B1/ru
Priority to GEAP19963957A priority patent/GEP20002211B/en
Priority to DK96909193T priority patent/DK0817780T3/da
Priority to CA002214321A priority patent/CA2214321C/fr
Priority to DE69606028T priority patent/DE69606028T2/de
Priority to KR1019970706762A priority patent/KR100485309B1/ko
Priority to JP52899696A priority patent/JP3790826B2/ja
Priority to AU52780/96A priority patent/AU711227B2/en
Priority to CZ19973032A priority patent/CZ287468B6/cs
Priority to SK1302-97A priority patent/SK281928B6/sk
Priority to PT96909192T priority patent/PT817779E/pt
Priority to BR9607929A priority patent/BR9607929A/pt
Priority to US08/913,972 priority patent/US5889043A/en
Priority to DK96909192T priority patent/DK0817779T3/da
Priority to JP8528995A priority patent/JP2941951B2/ja
Priority to SK1301-97A priority patent/SK281927B6/sk
Priority to TR97/01042T priority patent/TR199701042T1/xx
Priority to APAP/P/1997/001093A priority patent/AP753A/en
Priority to PCT/FR1996/000440 priority patent/WO1996030355A1/fr
Priority to HU9801204A priority patent/HU223732B1/hu
Priority to EA199700270A priority patent/EA000709B1/ru
Priority to CNB961928840A priority patent/CN1152870C/zh
Priority to SI9630098T priority patent/SI0817780T1/xx
Priority to APAP/P/1997/001090A priority patent/AP785A/en
Priority to AT96909192T priority patent/ATE188471T1/de
Priority to PCT/FR1996/000441 priority patent/WO1996030356A1/fr
Priority to EP96909192A priority patent/EP0817779B1/fr
Priority to ES96909192T priority patent/ES2143187T3/es
Priority to TR97/01040T priority patent/TR199701040T1/xx
Priority to CNB961928867A priority patent/CN1213042C/zh
Priority to PL96322465A priority patent/PL188284B1/pl
Priority to ZA962399A priority patent/ZA962399B/xx
Priority to DZ960050A priority patent/DZ2009A1/fr
Priority to TW085103611A priority patent/TW394765B/zh
Priority to US08/622,011 priority patent/US5847170A/en
Priority to MYPI96001132A priority patent/MY121225A/en
Priority to TNTNSN96043A priority patent/TNSN96043A1/fr
Priority to CO96015209A priority patent/CO4700576A1/es
Priority to UY24192A priority patent/UY24192A1/es
Priority to AR33592996A priority patent/AR001440A1/es
Priority to UY24370A priority patent/UY24370A1/es
Publication of FR2742754A1 publication Critical patent/FR2742754A1/fr
Priority to IS4536A priority patent/IS2058B/is
Priority to MXPA/A/1997/006278A priority patent/MXPA97006278A/xx
Priority to NO973923A priority patent/NO316607B1/no
Priority to NO19973922A priority patent/NO316379B1/no
Priority to MXPA/A/1997/006568A priority patent/MXPA97006568A/xx
Priority to IS4567A priority patent/IS2056B/is
Priority to BG101917A priority patent/BG63009B1/bg
Priority to BG101918A priority patent/BG63121B1/bg
Priority to OA70086A priority patent/OA10513A/fr
Priority to OA70087A priority patent/OA10514A/fr
Application granted granted Critical
Publication of FR2742754B1 publication Critical patent/FR2742754B1/fr
Priority to US09/066,929 priority patent/US6331635B1/en
Priority to GR990402228T priority patent/GR3031526T3/el
Priority to GR990402501T priority patent/GR3032316T3/el
Priority to US09/752,779 priority patent/US6372780B2/en
Priority to US09/985,956 priority patent/US6387946B1/en
Priority to US10/029,954 priority patent/US6593482B2/en
Priority to IL15937803A priority patent/IL159378A0/xx
Priority to PL96322499A priority patent/PL188987B1/pl
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR9515381A 1993-02-01 1995-12-22 Procede de preparation de taxoides Expired - Lifetime FR2742754B1 (fr)

Priority Applications (82)

Application Number Priority Date Filing Date Title
FR9515381A FR2742754B1 (fr) 1995-12-22 1995-12-22 Procede de preparation de taxoides
MA24180A MA23823A1 (fr) 1995-03-27 1996-03-08 Nouveaux taxoides, leur preparation et les compositions qui les contiennent
PE1996000181A PE51097A1 (es) 1995-03-27 1996-03-19 Nuevos taxoides, su preparacion y composiciones farmaceuticas que los contienen
IL11763696A IL117636A (en) 1995-03-27 1996-03-24 Taxoids, their preparation and pharmaceutical compositions containing them
IL15937896A IL159378A (en) 1995-03-27 1996-03-24 Intermediate in the preparation of taxoids
EE9700315A EE03608B1 (et) 1995-03-27 1996-03-25 Taksoidid, meetod nende valmistamiseks ja neid sisaldavad farmatseutilised kompositsioonid
CA002214319A CA2214319C (fr) 1995-03-27 1996-03-25 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
EP96909193A EP0817780B1 (fr) 1995-03-27 1996-03-25 Nouveaux taxo des, leur preparation et les compositions pharmaceutiques qui les contiennent
RO97-01794A RO115878B1 (ro) 1995-03-27 1996-03-25 Taxoide, procedee pentru prepararea lor si compozitie farmaceutica care le contine
EE9700323A EE03609B1 (et) 1995-03-27 1996-03-25 Taksoidid, meetod nende valmistamiseks ja neid sisaldavad farmatseutilised kompositsioonid
DE69604653T DE69604653T2 (de) 1995-03-27 1996-03-25 Taxol derivate, deren herstellung und diese enthaltende pharmazeutischen zusammenstellungen
RO97-01793A RO115877B1 (ro) 1995-03-27 1996-03-25 Taxoide, procedee pentru prepararea acestora şi compoziţie farmaceutică care le conţine
SI9630132T SI0817779T1 (en) 1995-03-27 1996-03-25 Novel taxoids, preparation thereof and pharmaceutical compositions containing same
ES96909193T ES2140075T3 (es) 1995-03-27 1996-03-25 Nuevos taxoides, su preparacion y las composiciones farmaceuticas que les contienen.
CZ19973030A CZ287326B6 (en) 1995-03-27 1996-03-25 Taxoids, process of their preparation and pharmaceutical composition in which the taxoids are comprised
AU52781/96A AU703278B2 (en) 1995-03-27 1996-03-25 New taxoids, their preparation and pharmaceutical compositions containing them
HU9801201A HU223666B1 (hu) 1995-03-27 1996-03-25 Taxoidok, előállításuk és ezeket tartalmazó gyógyszerkészítmények
NZ304900A NZ304900A (en) 1995-03-27 1996-03-25 Taxoid derivatives, preparation and pharmaceutical compositions thereof
AT96909193T ATE185562T1 (de) 1995-03-27 1996-03-25 Taxol derivate, deren herstellung und diese enthaltende pharmazeutischen zusammenstellungen
NZ304901A NZ304901A (en) 1995-03-27 1996-03-25 Taxoid derivatives, preparation thereof and pharmaceutical compositions containing same
BR9607930A BR9607930A (pt) 1995-03-27 1996-03-25 Taxóides processo de preparação de taxóides produto e composição farmacêutica que os contêm
GEAP19963956A GEP20002188B (en) 1995-03-27 1996-03-25 (54) Taxoids, Preparation Thereof and Pharmaceutical Compositions Containing Same
KR1019970706691A KR100297196B1 (ko) 1995-03-27 1996-03-25 신규택소이드,이의제조법및이를함유한약학조성물
EA199700269A EA000567B1 (ru) 1995-03-27 1996-03-25 Таксоиды, способы их получения и фармацевтическая композиция на их основе
GEAP19963957A GEP20002211B (en) 1995-03-27 1996-03-25 Taxoids, Preparation Thereof, Pharmaceutical Compositions Containing Same
DK96909193T DK0817780T3 (da) 1995-03-27 1996-03-25 Taxoider, fremstilling af disse forbindelser og farmaceutiske præparater indeholdende disse forbindelser
CA002214321A CA2214321C (fr) 1995-03-27 1996-03-25 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
DE69606028T DE69606028T2 (de) 1995-03-27 1996-03-25 Taxal derivate, deren herstellung und diese enthaltende pharmazeutische zusammensetzung
KR1019970706762A KR100485309B1 (ko) 1995-03-27 1996-03-25 신규택소이드,이의제조방법및이를함유하는약학조성물
JP52899696A JP3790826B2 (ja) 1995-03-27 1996-03-25 新規なタキソイド、その製造及びそれを含有する製薬学的組成物
AU52780/96A AU711227B2 (en) 1995-03-27 1996-03-25 Novel taxoids, preparation thereof and pharmaceutical compositions containing same
CZ19973032A CZ287468B6 (en) 1995-03-27 1996-03-25 Taxoids, process of their preparation and pharmaceutical preparation in which these taxoids are comprised
SK1302-97A SK281928B6 (sk) 1995-03-27 1996-03-25 Taxoidy, spôsob ich prípravy a farmaceutické kompozície obsahujúce tieto taxoidy
PT96909192T PT817779E (pt) 1995-03-27 1996-03-25 Novos taxoides, sua preparacao e composicoes farmaceuticas que os contem
BR9607929A BR9607929A (pt) 1995-03-27 1996-03-25 Toxóides processo de preparação de taxóides e de produto e composição farmacêutica que os contêm
US08/913,972 US5889043A (en) 1995-03-27 1996-03-25 Taxoids, preparation thereof and pharmaceutical Compositions containing same
DK96909192T DK0817779T3 (da) 1995-03-27 1996-03-25 Nye taxoider, deres fremstilling og farmaceutiske præparater deraf
JP8528995A JP2941951B2 (ja) 1995-03-27 1996-03-25 新規なタキソイド、その製造及びそれを含有する製薬学的組成物
SK1301-97A SK281927B6 (sk) 1995-03-27 1996-03-25 Taxoidy, spôsob ich prípravy, farmaceutické kompozície s ich obsahom a medziprodukt na ich prípravu
TR97/01042T TR199701042T1 (xx) 1995-03-27 1996-03-25 Yeni taksoidler, haz�rlan��lar�, ispen�iyari kompozisyonlar�.
APAP/P/1997/001093A AP753A (en) 1995-03-27 1996-03-25 Novel taxoids, preparation thereof and pharmaceutical compositions containing same.
PCT/FR1996/000440 WO1996030355A1 (fr) 1995-03-27 1996-03-25 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
HU9801204A HU223732B1 (hu) 1995-03-27 1996-03-25 Taxoidok, eljárás előállításukra és ezeket tartalmazó gyógyszerkészítmények
EA199700270A EA000709B1 (ru) 1995-03-27 1996-03-25 Таксоиды, способы их получения и фармацевтическая композиция на их основе и промежуточные соединения
CNB961928840A CN1152870C (zh) 1995-03-27 1996-03-25 新的紫杉化合物,其制备方法及其药物组合物
SI9630098T SI0817780T1 (en) 1995-03-27 1996-03-25 Novel taxoids, preparation thereof and pharmaceutical compositions containing same
APAP/P/1997/001090A AP785A (en) 1995-03-27 1996-03-25 Novel taxoids, preparation thereof and pharmaceutical compositions containing same.
AT96909192T ATE188471T1 (de) 1995-03-27 1996-03-25 Taxal derivate, deren herstellung und diese enthaltende pharmazeutische zusammensetzung
PCT/FR1996/000441 WO1996030356A1 (fr) 1995-03-27 1996-03-25 Nouveaux taxoïdes, leur preparation et les compositions pharmaceutiques qui les contiennent
EP96909192A EP0817779B1 (fr) 1995-03-27 1996-03-25 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
ES96909192T ES2143187T3 (es) 1995-03-27 1996-03-25 Nuevos taxoides, su preparacion y las composiciones farmaceuticas que les contienen.
TR97/01040T TR199701040T1 (xx) 1995-03-27 1996-03-25 Yeni taksoidler ve bunlar�n haz�rlanmas�.
CNB961928867A CN1213042C (zh) 1995-03-27 1996-03-25 紫杉化合物、其制备方法及其药物组合物
PL96322465A PL188284B1 (pl) 1995-03-27 1996-03-25 Nowe taksoidy, sposób ich wytwarzania i zawierające je kompozycje farmaceutyczne
ZA962399A ZA962399B (en) 1995-03-27 1996-03-26 Taxoids their preparation and pharmaceutical compositions containing them
DZ960050A DZ2009A1 (fr) 1995-03-27 1996-03-26 Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
TW085103611A TW394765B (en) 1995-03-27 1996-03-26 Taxoids, their preparation and pharmaceutical compositions containing them
US08/622,011 US5847170A (en) 1995-03-27 1996-03-26 Taxoids, their preparation and pharmaceutical compositions containing them
MYPI96001132A MY121225A (en) 1995-03-27 1996-03-26 Taxoids, their preparation and pharmaceutical compositions containing them
TNTNSN96043A TNSN96043A1 (fr) 1995-03-27 1996-03-26 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
CO96015209A CO4700576A1 (es) 1995-03-27 1996-03-27 Nuevos taxoides, su preparacion y las composiciones farmaceuticas que los contienen
UY24192A UY24192A1 (es) 1995-03-27 1996-03-27 Nuevos taxoides, su preparacion y las composiciones farmaceuticas que los contienen
AR33592996A AR001440A1 (es) 1995-03-27 1996-03-27 Nuevos taxoides, su preparación y composiciones farmacéuticas que los contienen.
UY24370A UY24370A1 (es) 1995-03-27 1996-11-20 Nuevos taxoides,eterificados en posición 7 y 10, su preparación y composiciones farmacéuticas parenterales que los contienen
IS4536A IS2058B (is) 1995-03-27 1997-07-31 Ný taxóíð, aðferð til framleiðslu þeirra og lyfjasamsetningar sem innihalda þau
MXPA/A/1997/006278A MXPA97006278A (en) 1995-03-27 1997-08-18 New taxoids, its preparation and the pharmaceutical compositions that contain them
NO973923A NO316607B1 (no) 1995-03-27 1997-08-26 Nye taxoider, deres fremstilling, mellomprodukter samt farmasøytiske preparater inneholdende forbindelsene
NO19973922A NO316379B1 (no) 1995-03-27 1997-08-26 Nye taxoider, deres fremstilling og farmas degree ytiske preparater inneholdende forbindelsene
MXPA/A/1997/006568A MXPA97006568A (en) 1995-03-27 1997-08-28 New taxoids, its preparation and pharmaceutical compositions that contains them
IS4567A IS2056B (is) 1995-03-27 1997-09-23 Ný taxóíð, aðferð til að búa þau til og lyfjasamsetningar sem innihalda þau
BG101917A BG63009B1 (bg) 1995-03-27 1997-09-25 Таксоиди,тяхното получаване и фармацевтични състави, които ги съдържат
BG101918A BG63121B1 (bg) 1995-03-27 1997-09-25 Таксоиди, тяхното получаване и фармацевтични състави, които ги съдържат
OA70086A OA10513A (fr) 1995-03-27 1997-09-26 Nouveaux taxoides leur préparation et les compositions pharmaceutiques qui les contiennent
OA70087A OA10514A (fr) 1995-03-27 1997-09-26 Nouveaux taxoides leur préparation et les compositions pharmaceutiques qui les contiennent
US09/066,929 US6331635B1 (en) 1995-03-27 1998-04-28 Taxoids, their preparation and pharmaceutical compositions containing them
GR990402228T GR3031526T3 (en) 1995-03-27 1999-10-14 Novel taxoids, preparation thereof and pharmaceutical compositions containing same
GR990402501T GR3032316T3 (en) 1995-03-27 2000-01-07 Novel taxoids, preparation thereof and pharmaceutical compositions containing same
US09/752,779 US6372780B2 (en) 1995-03-27 2001-01-03 Methods of treating cell lines expressing multidrug resistance P-glycoprotein
US09/985,956 US6387946B1 (en) 1995-03-27 2001-09-25 Methods for treating pathological conditions of abnormal cell proliferation
US10/029,954 US6593482B2 (en) 1993-02-01 2001-12-31 Methods for preparing new taxoids and pharmaceutical compositions containing them
IL15937803A IL159378A0 (en) 1995-03-27 2003-12-15 Intermediate in the preparation of taxoids
PL96322499A PL188987B1 (pl) 1995-03-27 2007-09-11 Nowe taksoidy i sposób ich wytwarzania

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9515381A FR2742754B1 (fr) 1995-12-22 1995-12-22 Procede de preparation de taxoides

Publications (2)

Publication Number Publication Date
FR2742754A1 FR2742754A1 (fr) 1997-06-27
FR2742754B1 true FR2742754B1 (fr) 1998-01-16

Family

ID=9485873

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9515381A Expired - Lifetime FR2742754B1 (fr) 1993-02-01 1995-12-22 Procede de preparation de taxoides

Country Status (1)

Country Link
FR (1) FR2742754B1 (fr)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL112412A (en) * 1994-01-28 2000-02-29 Upjohn Co Delta 12,13-iso-taxol analogs and antineoplastic pharmaceutical compositions containing them

Also Published As

Publication number Publication date
FR2742754A1 (fr) 1997-06-27

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