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FR2660659B1 - Polypeptides ayant une activite de recepteur dopaminergique, acides nucleiques codant pour ces polypeptides et utilisation de ces polypeptides pour le criblage de substances actives sur ces polypeptides. - Google Patents

Polypeptides ayant une activite de recepteur dopaminergique, acides nucleiques codant pour ces polypeptides et utilisation de ces polypeptides pour le criblage de substances actives sur ces polypeptides.

Info

Publication number
FR2660659B1
FR2660659B1 FR909004476A FR9004476A FR2660659B1 FR 2660659 B1 FR2660659 B1 FR 2660659B1 FR 909004476 A FR909004476 A FR 909004476A FR 9004476 A FR9004476 A FR 9004476A FR 2660659 B1 FR2660659 B1 FR 2660659B1
Authority
FR
France
Prior art keywords
polypeptides
nucleic acids
active substances
acids encoding
receptor activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR909004476A
Other languages
English (en)
Other versions
FR2660659A1 (fr
Inventor
Sokoloff Pierre
Martres Marie-Pascale
Schwartz Jean-Charles
Giros Bruno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut National de la Sante et de la Recherche Medicale INSERM
Original Assignee
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Institut National de la Sante et de la Recherche Medicale INSERM
Priority to FR909004476A priority Critical patent/FR2660659B1/fr
Priority to FR9008027A priority patent/FR2663638B2/fr
Priority to EP97100517A priority patent/EP0783037A1/fr
Priority to PCT/FR1991/000269 priority patent/WO1991015513A1/fr
Priority to AT91907472T priority patent/ATE155794T1/de
Priority to EP91907472A priority patent/EP0474846B1/fr
Priority to DE69126931T priority patent/DE69126931T2/de
Priority to US07/781,254 priority patent/US5407823A/en
Priority to JP03506941A priority patent/JP3112936B2/ja
Priority to CA002060325A priority patent/CA2060325C/fr
Priority to ES91907472T priority patent/ES2106778T3/es
Publication of FR2660659A1 publication Critical patent/FR2660659A1/fr
Application granted granted Critical
Publication of FR2660659B1 publication Critical patent/FR2660659B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/286Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against neuromediator receptors, e.g. serotonin receptor, dopamine receptor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
FR909004476A 1990-04-06 1990-04-06 Polypeptides ayant une activite de recepteur dopaminergique, acides nucleiques codant pour ces polypeptides et utilisation de ces polypeptides pour le criblage de substances actives sur ces polypeptides. Expired - Lifetime FR2660659B1 (fr)

Priority Applications (11)

Application Number Priority Date Filing Date Title
FR909004476A FR2660659B1 (fr) 1990-04-06 1990-04-06 Polypeptides ayant une activite de recepteur dopaminergique, acides nucleiques codant pour ces polypeptides et utilisation de ces polypeptides pour le criblage de substances actives sur ces polypeptides.
FR9008027A FR2663638B2 (fr) 1990-04-06 1990-06-26 Polypeptides ayant une activite de recepteur dopaminergique, acides nucleiques codant pour ces polypeptides et utilisation de ces polypeptides pour le criblage de substances actives sur ces polypeptides.
CA002060325A CA2060325C (fr) 1990-04-06 1991-04-03 Polypeptides ayant une activite de recepteur dopaminergique, acides nucleiques codant pour ces polypeptides et utilisation de ces polypeptides pour le criblage de substances actives sur ces polypeptides
AT91907472T ATE155794T1 (de) 1990-04-06 1991-04-03 Polypeptide mit dopaminerger rezeptor-aktivität, für sie kodierende nukleinsäuren und ihre verwendung
EP91907472A EP0474846B1 (fr) 1990-04-06 1991-04-03 Polypeptides ayant une activite de recepteur dopaminergique, acides nucleiques codant pour ces polypeptides et utilisation de ces polypeptides pour le criblage de substances actives sur ces polypeptides
DE69126931T DE69126931T2 (de) 1990-04-06 1991-04-03 Polypeptide mit dopaminerger rezeptor-aktivität, für sie kodierende nukleinsäuren und ihre verwendung
EP97100517A EP0783037A1 (fr) 1990-04-06 1991-04-03 Polypetides ayant une activité de récepteur dopaminergique (Dd2-R et D3-R) et utilisation de ces polypeptides pour le criblage de substances activés sur ces polypeptides
JP03506941A JP3112936B2 (ja) 1990-04-06 1991-04-03 ドーパミン受容体活性を有するポリペプチド、これらのポリペプチドをコードする核酸及びこれらのポリペプチドに対して活性な物質をスクリーニングするためのこれらのポリペプチドの使用
PCT/FR1991/000269 WO1991015513A1 (fr) 1990-04-06 1991-04-03 Polypeptides ayant une activite de recepteur dopaminergique, acides nucleiques codant pour ces polypeptides et utilisation de ces polypeptides pour le criblage de substances actives sur ces polypeptides
ES91907472T ES2106778T3 (es) 1990-04-06 1991-04-03 Polipeptidos con actividad de receptor dopaminergico, acidos nucleicos que codifican para estos polipeptidos y uso de estos polipeptidos para la deteccion de sustancias activas sobre estos polipeptidos.
US07/781,254 US5407823A (en) 1990-04-06 1991-04-03 Polypeptides having a dopaminergic receptor activity, nucleic acids coding for these polypeptides and use of these polypeptides for the screening of substances active on these polypeptides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR909004476A FR2660659B1 (fr) 1990-04-06 1990-04-06 Polypeptides ayant une activite de recepteur dopaminergique, acides nucleiques codant pour ces polypeptides et utilisation de ces polypeptides pour le criblage de substances actives sur ces polypeptides.

Publications (2)

Publication Number Publication Date
FR2660659A1 FR2660659A1 (fr) 1991-10-11
FR2660659B1 true FR2660659B1 (fr) 1994-06-10

Family

ID=9395536

Family Applications (1)

Application Number Title Priority Date Filing Date
FR909004476A Expired - Lifetime FR2660659B1 (fr) 1990-04-06 1990-04-06 Polypeptides ayant une activite de recepteur dopaminergique, acides nucleiques codant pour ces polypeptides et utilisation de ces polypeptides pour le criblage de substances actives sur ces polypeptides.

Country Status (1)

Country Link
FR (1) FR2660659B1 (fr)

Also Published As

Publication number Publication date
FR2660659A1 (fr) 1991-10-11

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