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FR2646424B1 - Procede de preparation de derives de la 1,5-benzothiazepine - Google Patents

Procede de preparation de derives de la 1,5-benzothiazepine

Info

Publication number
FR2646424B1
FR2646424B1 FR9005323A FR9005323A FR2646424B1 FR 2646424 B1 FR2646424 B1 FR 2646424B1 FR 9005323 A FR9005323 A FR 9005323A FR 9005323 A FR9005323 A FR 9005323A FR 2646424 B1 FR2646424 B1 FR 2646424B1
Authority
FR
France
Prior art keywords
formula
benzothiazepine derivatives
preparation
chem
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR9005323A
Other languages
English (en)
Other versions
FR2646424A1 (fr
Inventor
Hayashi Hironori
Nishimoto Shigeru
Okuno Tamotsu
Kitano Masashi
Maeda Sadao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Publication of FR2646424A1 publication Critical patent/FR2646424A1/fr
Application granted granted Critical
Publication of FR2646424B1 publication Critical patent/FR2646424B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
FR9005323A 1989-04-28 1990-04-26 Procede de preparation de derives de la 1,5-benzothiazepine Expired - Lifetime FR2646424B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1109795A JPH0798813B2 (ja) 1989-04-28 1989-04-28 １，５―ベンゾチアゼピン誘導体の製法

Publications (2)

Publication Number Publication Date
FR2646424A1 FR2646424A1 (fr) 1990-11-02
FR2646424B1 true FR2646424B1 (fr) 1994-05-20

Family

ID=14519414

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9005323A Expired - Lifetime FR2646424B1 (fr) 1989-04-28 1990-04-26 Procede de preparation de derives de la 1,5-benzothiazepine

Country Status (16)

Country Link
EP (1) EP0395323B1 (fr)
JP (1) JPH0798813B2 (fr)
KR (1) KR970002466B1 (fr)
CN (3) CN1031708C (fr)
AT (1) ATE154348T1 (fr)
AU (1) AU616351B2 (fr)
DE (1) DE69030897T2 (fr)
DK (1) DK0395323T3 (fr)
ES (1) ES2106018T3 (fr)
FI (1) FI109533B (fr)
FR (1) FR2646424B1 (fr)
GR (1) GR3023767T3 (fr)
HK (1) HK1003789A1 (fr)
HU (1) HU203882B (fr)
IL (1) IL94208A0 (fr)
SG (1) SG47004A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE116643T1 (de) * 1989-04-28 1995-01-15 Tanabe Seiyaku Co Verfahren zur herstellung von 1,5- benzothiazepinderivaten.
IT1234387B (it) * 1989-07-12 1992-05-18 Zambon Spa Processo di purificazione di intermedi utili nella preparazione del diltiazem
AU628217B2 (en) * 1989-08-31 1992-09-10 Marion Merrell Dow Inc. Heterogeneous synthesis of azepinones from esters
JPH085869B2 (ja) * 1990-03-08 1996-01-24 田辺製薬株式会社 １，５−ベンゾチアゼピン誘導体の製法
IT1249318B (it) * 1991-05-23 1995-02-22 Zambon Spa Processo per la preparazione di benzotiazepine per ciclizzazione con acidi fosfonici
DE4206714A1 (de) * 1992-03-04 1993-09-09 Sandoz Ag Wachsdispersionen, deren herstellung und verwendung
NL1002687C2 (nl) * 1996-03-22 1997-09-23 Dsm Nv Werkwijze voor de bereiding van een benzothiazepine.
IL123352A0 (en) 1997-02-27 1998-09-24 Tanabe Seiyaku Co Process for preparing an optically active trans-3-substituted glycidic acid ester
IT1295376B1 (it) * 1997-10-22 1999-05-12 Zambon Spa Processo per il riciclo di un sottoprodotto della sintesi del diltiazem
CN116143723A (zh) * 2022-12-07 2023-05-23 海南锦瑞制药有限公司 一种盐酸地尔硫卓的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3374865D1 (en) * 1982-07-07 1988-01-21 Siegfried Ag Process for preparing 4-hydroxy-2-methyl-n-2-pyridyl-2h-1,2-benzothiazine-3-carboxamide 1,1-dioxide
US4552695A (en) * 1983-04-21 1985-11-12 Shionogi & Co., Ltd. Process for production of diltiazem hydrochloride
ZA893392B (en) * 1988-05-24 1990-01-31 Hoffmann La Roche Process for the manufacture of optically active naphthothiazepinones
FR2641535B1 (fr) * 1989-01-11 1991-03-15 Synthelabo Procede de preparation de (+) - (2s, 3s)-hydroxy-3 (methoxy-4 phenyl)-2 dihydro-2,3 5h-benzothiazepine-1,5 one-4
ATE116643T1 (de) * 1989-04-28 1995-01-15 Tanabe Seiyaku Co Verfahren zur herstellung von 1,5- benzothiazepinderivaten.
JPH085869B2 (ja) * 1990-03-08 1996-01-24 田辺製薬株式会社 １，５−ベンゾチアゼピン誘導体の製法

Also Published As

Publication number Publication date
ES2106018T3 (es) 1997-11-01
IL94208A0 (en) 1991-01-31
DE69030897D1 (de) 1997-07-17
FR2646424A1 (fr) 1990-11-02
HU902607D0 (en) 1990-09-28
DK0395323T3 (da) 1997-09-08
JPH0798813B2 (ja) 1995-10-25
CN1046901A (zh) 1990-11-14
CN1110684A (zh) 1995-10-25
KR970002466B1 (ko) 1997-03-05
SG47004A1 (en) 1998-03-20
CN1136205C (zh) 2004-01-28
FI902030A0 (fi) 1990-04-23
FI109533B (fi) 2002-08-30
CN1245802A (zh) 2000-03-01
GR3023767T3 (en) 1997-09-30
CN1052479C (zh) 2000-05-17
EP0395323A1 (fr) 1990-10-31
KR900016171A (ko) 1990-11-12
AU616351B2 (en) 1991-10-24
DE69030897T2 (de) 1997-09-25
EP0395323B1 (fr) 1997-06-11
JPH02286672A (ja) 1990-11-26
AU5385690A (en) 1990-11-01
HK1003789A1 (en) 1998-11-06
HU203882B (en) 1991-10-28
ATE154348T1 (de) 1997-06-15
HUT55373A (en) 1991-05-28
CN1031708C (zh) 1996-05-01

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