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FR2640625B2 - Nouveaux composes optiquement actifs derives de l'indane, leur application comme medicaments et les compositions pharmaceutiques les renfermant - Google Patents

Nouveaux composes optiquement actifs derives de l'indane, leur application comme medicaments et les compositions pharmaceutiques les renfermant

Info

Publication number
FR2640625B2
FR2640625B2 FR888816605A FR8816605A FR2640625B2 FR 2640625 B2 FR2640625 B2 FR 2640625B2 FR 888816605 A FR888816605 A FR 888816605A FR 8816605 A FR8816605 A FR 8816605A FR 2640625 B2 FR2640625 B2 FR 2640625B2
Authority
FR
France
Prior art keywords
indane
drugs
application
pharmaceutical compositions
optically active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR888816605A
Other languages
English (en)
Other versions
FR2640625A2 (fr
Inventor
Francois Clemence
Michel Fortin
Gilles Hamon
Odile Le Martret
Anne-Marie Moura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8611927A external-priority patent/FR2603035B1/fr
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR888816605A priority Critical patent/FR2640625B2/fr
Priority to DK626889A priority patent/DK626889A/da
Priority to JP1322788A priority patent/JP2753591B2/ja
Priority to AU46802/89A priority patent/AU630136B2/en
Priority to ES89403506T priority patent/ES2059805T3/es
Priority to AT89403506T priority patent/ATE95517T1/de
Priority to CA002005626A priority patent/CA2005626A1/fr
Priority to DE89403506T priority patent/DE68909757T2/de
Priority to EP89403506A priority patent/EP0374054B1/fr
Priority to HU631/89A priority patent/HU219446B/hu
Priority to IE402789A priority patent/IE65151B1/en
Priority to ZA899616A priority patent/ZA899616B/xx
Publication of FR2640625A2 publication Critical patent/FR2640625A2/fr
Publication of FR2640625B2 publication Critical patent/FR2640625B2/fr
Application granted granted Critical
Priority to US08/096,034 priority patent/US5436244A/en
Priority to US08/105,329 priority patent/US5348971A/en
Priority to BG98525A priority patent/BG61121B2/bg
Priority to HU95P/P00668P priority patent/HU211609A9/hu
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/96—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings spiro-condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR888816605A 1986-08-21 1988-12-16 Nouveaux composes optiquement actifs derives de l'indane, leur application comme medicaments et les compositions pharmaceutiques les renfermant Expired - Lifetime FR2640625B2 (fr)

Priority Applications (16)

Application Number Priority Date Filing Date Title
FR888816605A FR2640625B2 (fr) 1986-08-21 1988-12-16 Nouveaux composes optiquement actifs derives de l'indane, leur application comme medicaments et les compositions pharmaceutiques les renfermant
DK626889A DK626889A (da) 1988-12-16 1989-12-12 Indanderivater, deres fremstilling samt laegemidler med indhold deraf
JP1322788A JP2753591B2 (ja) 1988-12-16 1989-12-14 インダンから誘導される化合物の薬剤としての使用並びにそれらを含有する製薬組成物
EP89403506A EP0374054B1 (fr) 1988-12-16 1989-12-15 Composés dérivés de l'indane, leur procédé et les intermédiaires de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant
ES89403506T ES2059805T3 (es) 1988-12-16 1989-12-15 Compuestos derivados del indano, su procedimiento y los productos intermedios para su preparacion, su aplicacion como medicamentos y composiciones farmaceuticas que los contienen.
AT89403506T ATE95517T1 (de) 1988-12-16 1989-12-15 Indanderivate, verfahren zu ihrer herstellung und erhaltene zwischenprodukte, ihre verwendung als arzneimittel und diese enthaltende pharmazeutische zusammensetzungen.
CA002005626A CA2005626A1 (fr) 1988-12-16 1989-12-15 Nouveaux composes derives de l'indane, leur procede et les intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
DE89403506T DE68909757T2 (de) 1988-12-16 1989-12-15 Indanderivate, Verfahren zu ihrer Herstellung und erhaltene Zwischenprodukte, ihre Verwendung als Arzneimittel und diese enthaltende pharmazeutische Zusammensetzungen.
AU46802/89A AU630136B2 (en) 1988-12-16 1989-12-15 New compounds derived from indane, their preparation process and intermediates, their use as medicaments and the pharmaceutical compositions containing them
HU631/89A HU219446B (hu) 1988-12-16 1989-12-15 Indánszármazékok, és ilyen vegyületeket tartalmazó gyógyászati készítmények és eljárás előállításukra
IE402789A IE65151B1 (en) 1988-12-16 1989-12-15 New compounds derived from indane their preparation process and intermediates their use as medicaments and the pharmaceutical compositions containing them
ZA899616A ZA899616B (en) 1988-12-16 1989-12-15 Compounds derived from indane,their preparation process and intermediates,their use as medicaments and the pharmaceutical compositions containing them
US08/096,034 US5436244A (en) 1988-12-16 1993-07-22 Indane derivatives and analgesic and diuretic compositions thereof
US08/105,329 US5348971A (en) 1988-12-16 1993-08-09 Indanes useful as analgesics
BG98525A BG61121B2 (bg) 1988-12-16 1994-02-23 Съединения,производни на индана,метод за получаване и междинни продукти при получаването,тяхното приложение като лекарствени средства и съдържащите ги фармацевтични състави
HU95P/P00668P HU211609A9 (en) 1988-12-16 1995-06-30 Indan derivatives, process and intermediates to the production thereof, their use as medicament and pharmaceutical compositions containing the same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8611927A FR2603035B1 (fr) 1986-08-21 1986-08-21 Nouveaux derives de l'indane, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant
FR888816605A FR2640625B2 (fr) 1986-08-21 1988-12-16 Nouveaux composes optiquement actifs derives de l'indane, leur application comme medicaments et les compositions pharmaceutiques les renfermant

Publications (2)

Publication Number Publication Date
FR2640625A2 FR2640625A2 (fr) 1990-06-22
FR2640625B2 true FR2640625B2 (fr) 1993-05-21

Family

ID=26225446

Family Applications (1)

Application Number Title Priority Date Filing Date
FR888816605A Expired - Lifetime FR2640625B2 (fr) 1986-08-21 1988-12-16 Nouveaux composes optiquement actifs derives de l'indane, leur application comme medicaments et les compositions pharmaceutiques les renfermant

Country Status (1)

Country Link
FR (1) FR2640625B2 (fr)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1109080A (fr) * 1978-05-30 1981-09-15 Hideo Kato Derives de l'indanamine
GB2096607B (en) * 1981-04-09 1985-02-27 Upjohn Co Aminocycloalkyl amides
US4876269A (en) * 1986-09-10 1989-10-24 E. I. Du Pont De Nemours And Company Benoz-fused cycloalkane trans-1,2-diamine derivatives

Also Published As

Publication number Publication date
FR2640625A2 (fr) 1990-06-22

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Legal Events

Date Code Title Description
CA Change of address
CD Change of name or company name
TP Transmission of property
TP Transmission of property