[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

FR2501209B1 - Nouveaux derives des cephalosporines et medicaments antibiotiques contenant lesdits derives - Google Patents

Nouveaux derives des cephalosporines et medicaments antibiotiques contenant lesdits derives

Info

Publication number
FR2501209B1
FR2501209B1 FR8104243A FR8104243A FR2501209B1 FR 2501209 B1 FR2501209 B1 FR 2501209B1 FR 8104243 A FR8104243 A FR 8104243A FR 8104243 A FR8104243 A FR 8104243A FR 2501209 B1 FR2501209 B1 FR 2501209B1
Authority
FR
France
Prior art keywords
drugs containing
same
cephalosporin derivatives
antibiotic drugs
novel cephalosporin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8104243A
Other languages
English (en)
Other versions
FR2501209A1 (fr
Inventor
Bernard Labeeuw
Ali Salhi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Priority to FR8104243A priority Critical patent/FR2501209B1/fr
Priority to GR65352A priority patent/GR75711B/el
Priority to GR65351A priority patent/GR75706B/el
Priority to DE8181401027T priority patent/DE3162109D1/de
Priority to AT81401028T priority patent/ATE7394T1/de
Priority to EP81401028A priority patent/EP0043756B1/fr
Priority to DE8181401028T priority patent/DE3163490D1/de
Priority to AT81401027T priority patent/ATE6066T1/de
Priority to EP81401027A priority patent/EP0044238B1/fr
Priority to DK283281A priority patent/DK283281A/da
Priority to DK283381A priority patent/DK283381A/da
Priority to PT73284A priority patent/PT73284A/fr
Priority to IE1453/81A priority patent/IE51359B1/en
Priority to IE1452/81A priority patent/IE51358B1/en
Priority to NO812215A priority patent/NO159798C/no
Priority to NZ197563A priority patent/NZ197563A/xx
Priority to NO812214A priority patent/NO812214L/no
Priority to PT73283A priority patent/PT73283B/fr
Priority to NZ197564A priority patent/NZ197564A/xx
Priority to CA000380874A priority patent/CA1175806A/fr
Priority to ES503562A priority patent/ES8204996A1/es
Priority to ES81503563A priority patent/ES8203384A1/es
Priority to CA000380872A priority patent/CA1173434A/fr
Priority to AU72411/81A priority patent/AU543165B2/en
Priority to MX10176881U priority patent/MX6880E/es
Priority to AT82400321T priority patent/ATE18403T1/de
Priority to DE8282400321T priority patent/DE3269543D1/de
Priority to EP82400321A priority patent/EP0060745B1/fr
Priority to IL65110A priority patent/IL65110A/xx
Priority to PT74511A priority patent/PT74511B/fr
Priority to DK88382A priority patent/DK88382A/da
Priority to ZA821365A priority patent/ZA821365B/xx
Priority to NO820649A priority patent/NO820649L/no
Priority to FI820736A priority patent/FI73441C/fi
Priority to ES510068A priority patent/ES8305371A1/es
Priority to GR67456A priority patent/GR74749B/el
Priority to US06/353,890 priority patent/US4476123A/en
Priority to NZ199875A priority patent/NZ199875A/xx
Priority to IE463/82A priority patent/IE52767B1/en
Priority to CA000397356A priority patent/CA1191838A/fr
Priority to JP57032488A priority patent/JPS57158791A/ja
Priority to AU81061/82A priority patent/AU559122B2/en
Publication of FR2501209A1 publication Critical patent/FR2501209A1/fr
Priority to US06/525,797 priority patent/US4604387A/en
Application granted granted Critical
Publication of FR2501209B1 publication Critical patent/FR2501209B1/fr
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/555—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound pre-targeting systems involving an organic compound, other than a peptide, protein or antibody, for targeting specific cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Train Traffic Observation, Control, And Security (AREA)
  • Bakery Products And Manufacturing Methods Therefor (AREA)
FR8104243A 1980-06-30 1981-03-03 Nouveaux derives des cephalosporines et medicaments antibiotiques contenant lesdits derives Expired FR2501209B1 (fr)

Priority Applications (43)

Application Number Priority Date Filing Date Title
FR8104243A FR2501209B1 (fr) 1981-03-03 1981-03-03 Nouveaux derives des cephalosporines et medicaments antibiotiques contenant lesdits derives
GR65351A GR75706B (fr) 1980-06-30 1981-06-25
GR65352A GR75711B (fr) 1980-06-30 1981-06-25
DK283381A DK283381A (da) 1980-06-30 1981-06-26 Fremgangsmaade til fremstilling af 1,2,4-triazinylthiomethyl-3-cephem-sulfoxid
EP81401028A EP0043756B1 (fr) 1980-06-30 1981-06-26 1,2,4-Triazinylthiométhyl-3-céphèmes sulfoxydes, procédé de préparation et compositions pharmaceutiques en contenant
DE8181401028T DE3163490D1 (en) 1980-06-30 1981-06-26 1,2,4-triazinylthiomethyl-3-cephem sulfoxides, process for their preparation and pharmaceutical compositions containing them
AT81401027T ATE6066T1 (de) 1980-06-30 1981-06-26 Cephalosporinsulfoxyd-verbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate.
EP81401027A EP0044238B1 (fr) 1980-06-30 1981-06-26 Dérivés de céphalosporines sulfoxydes, procédé de préparation et compositions pharmaceutiques en contenant
DE8181401027T DE3162109D1 (en) 1980-06-30 1981-06-26 Cephalosporin sulfoxides, process for their preparation and pharmaceutical compositions containing them
AT81401028T ATE7394T1 (de) 1980-06-30 1981-06-26 1,2,4-triazinylthiomethyl-3-cephem-sulfoxyde, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate.
DK283281A DK283281A (da) 1980-06-30 1981-06-26 Fremgangsmaade til fremstilling af sulfoxidderivater af cephalosporiner
IE1453/81A IE51359B1 (en) 1980-06-30 1981-06-29 Derivatives of cephalosporin sulphoxides,process for their preparation and pharmaceutical compositions containing them
IE1452/81A IE51358B1 (en) 1980-06-30 1981-06-29 1,2,4-triazinylthiomethyl-3-cephem sulfoxides,process for their preparation and pharmaceutical compositions containing them
NO812215A NO159798C (no) 1980-06-30 1981-06-29 Analogifremgangsmaate for fremstilling av terapeutisk aktive cefalosporin-oksyder.
NZ197563A NZ197563A (en) 1980-06-30 1981-06-29 3-(1,2,4-triazinylthiomethyl)-3-cephem-1-sulphoxide derivatives
NO812214A NO812214L (no) 1980-06-30 1981-06-29 Fremgangsmaate for fremstilling av 3-(hydroksy-1,2,4-triazinyl)tiometyl-cefalosporiner
PT73283A PT73283B (fr) 1980-06-30 1981-06-29 Procede de preparation d'oxides de cephalosporines
NZ197564A NZ197564A (en) 1980-06-30 1981-06-29 Cephalosporin sulphoxide derivatives and pharmaceutical compositions
PT73284A PT73284A (fr) 1980-06-30 1981-06-29 Procede de preparation de derives de cephalosporines sulfoxides
CA000380872A CA1173434A (fr) 1980-06-30 1981-06-30 1,2,4-triazinylthiomethyl-3-cepheme-sulfoxydes; preparation et utilisation en pharmacie
ES503562A ES8204996A1 (es) 1980-06-30 1981-06-30 Procedimiento de preparacion de 3-(1,2,4-hidroxitriazinil) tiometil cefalosporinas
ES81503563A ES8203384A1 (es) 1980-06-30 1981-06-30 Procedimiento de preparacion de cefalosporinas oxidas
CA000380874A CA1175806A (fr) 1980-06-30 1981-06-30 Preparation de derives de sulphoxydes de cephalosporine et compose pharmaceutique les contenant
AU72411/81A AU543165B2 (en) 1980-06-30 1981-06-30 Cephalosporins
MX10176881U MX6880E (es) 1980-06-30 1981-06-30 Procedimiento de preparacion de 1,2,4-triaziniltiometil-3-cefem sulfoxidos
AT82400321T ATE18403T1 (de) 1981-03-03 1982-02-24 Antibiotische cephalosporinverbindungen.
DE8282400321T DE3269543D1 (en) 1981-03-03 1982-02-24 Antibiotic derivatives from cephalosporins
EP82400321A EP0060745B1 (fr) 1981-03-03 1982-02-24 Nouveaux dérivés antibiotiques dérivés des céphalosporines
IL65110A IL65110A (en) 1981-03-03 1982-02-25 Derivatives of 3-cephem-4-carboxylic acid 1-s-oxide,their preparation and pharmaceutical compositions containing them
DK88382A DK88382A (da) 1981-03-03 1982-03-01 Fremgangsmaade til fremstilling af cephalosparinderivater
PT74511A PT74511B (fr) 1981-03-03 1982-03-01 Procede de preparation de nouveaux derives des cephalosporines presentant des proprietes antibiotiques
ZA821365A ZA821365B (en) 1981-03-03 1982-03-02 Antibiotic derivatives,derived from cephalosporins
FI820736A FI73441C (fi) 1981-03-03 1982-03-02 Foerfarande foer framstaellning av nya 3-(substituerad metyl)-3-cefem-4-karboxylsyra-1-s-oxider med antibiotiska egenskaper.
ES510068A ES8305371A1 (es) 1981-03-03 1982-03-02 Procedimiento de preparacion de derivados de la familia de las cefalosporinas.
GR67456A GR74749B (fr) 1981-03-03 1982-03-02
US06/353,890 US4476123A (en) 1981-03-03 1982-03-02 Antibiotic derivatives, derived from cephalosporins with thiazolyl substituents, pharmaceutical preparations and salts thereof
NZ199875A NZ199875A (en) 1981-03-03 1982-03-02 Cephalosporin derivatives and pharmaceutical compositions
NO820649A NO820649L (no) 1981-03-03 1982-03-02 Fremgangsmaate for fremstilling av antibiotisk aktive cefalosporiner.
CA000397356A CA1191838A (fr) 1981-03-03 1982-03-02 Derives de la cephalosporine antibiotiques
IE463/82A IE52767B1 (en) 1981-03-03 1982-03-02 Antibiotic derivatives, derived from cephalosporins
JP57032488A JPS57158791A (en) 1981-03-03 1982-03-03 Novel antibiotic derivatives derived from cephalosporin
AU81061/82A AU559122B2 (en) 1981-03-03 1982-03-03 Cephalosporin derivatives
US06/525,797 US4604387A (en) 1980-06-30 1983-08-23 1,2,4-triazinylthiomethyl-3-cephem sulfoxides, and a procedure for their preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8104243A FR2501209B1 (fr) 1981-03-03 1981-03-03 Nouveaux derives des cephalosporines et medicaments antibiotiques contenant lesdits derives

Publications (2)

Publication Number Publication Date
FR2501209A1 FR2501209A1 (fr) 1982-09-10
FR2501209B1 true FR2501209B1 (fr) 1986-07-04

Family

ID=9255827

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8104243A Expired FR2501209B1 (fr) 1980-06-30 1981-03-03 Nouveaux derives des cephalosporines et medicaments antibiotiques contenant lesdits derives

Country Status (18)

Country Link
US (1) US4476123A (fr)
EP (1) EP0060745B1 (fr)
JP (1) JPS57158791A (fr)
AT (1) ATE18403T1 (fr)
AU (1) AU559122B2 (fr)
CA (1) CA1191838A (fr)
DE (1) DE3269543D1 (fr)
DK (1) DK88382A (fr)
ES (1) ES8305371A1 (fr)
FI (1) FI73441C (fr)
FR (1) FR2501209B1 (fr)
GR (1) GR74749B (fr)
IE (1) IE52767B1 (fr)
IL (1) IL65110A (fr)
NO (1) NO820649L (fr)
NZ (1) NZ199875A (fr)
PT (1) PT74511B (fr)
ZA (1) ZA821365B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4507487A (en) * 1982-09-23 1985-03-26 Bristol-Myers Company Chemical compounds
EP0115770B2 (fr) * 1983-01-07 1996-06-19 Takeda Chemical Industries, Ltd. Dérivés de thiazoles
FR2546520B1 (fr) * 1983-05-27 1985-08-30 Sanofi Sa Nouveaux composes antibiotiques derives des cephalosporines
FR2570702B1 (fr) * 1984-09-27 1987-01-09 Sanofi Sa Derives des cephalosporines, procedes d'obtention et leur application a titre d'antibiotiques
US4665066A (en) * 1984-12-24 1987-05-12 Eli Lilly And Company 3-thiazolomethyl cephalosporins as antibiotics
US5359057A (en) * 1986-02-07 1994-10-25 Hoffmann-La Roche Inc. Acylation of amines
US5147871A (en) * 1986-07-03 1992-09-15 Hoffmann La-Roche, Inc. Anti-bacterial cephalosporin compounds
ZA874696B (en) * 1986-07-03 1988-01-04 F. Hoffmann-La Roche & Co. Aktiengesellschaft Acyl derivatives
CS273349B2 (en) * 1988-03-31 1991-03-12 Hoffmann La Roche Method of cephalosporin's new derivatives production
US5336768A (en) * 1988-05-24 1994-08-09 Hoffmann-La Roche Inc. Antibacterial cephalosporin compounds
GB8907617D0 (en) * 1989-04-05 1989-05-17 Celltech Ltd Drug delivery system
US5159077A (en) * 1989-07-21 1992-10-27 Hoffmann-La Roche Inc. Penam antibacterial compounds
US5162523A (en) * 1989-07-21 1992-11-10 Hoffmann-La Roche Inc. Cephalosporin antibacterial compounds
US5318781A (en) * 1993-04-06 1994-06-07 Hoffmann-La Roche Inc. Absorption enhancement of antibiotics

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5919114B2 (ja) * 1975-08-25 1984-05-02 武田薬品工業株式会社 セフアロスポリンの製造法
US4165430A (en) * 1976-03-19 1979-08-21 Glaxo Laboratories Limited Cephalosporins having a 7-carboxy substituted α-etherified oximinoarylacetamido) group
DE2716677C2 (de) * 1977-04-15 1985-10-10 Hoechst Ag, 6230 Frankfurt Cephemderivate und Verfahren zu ihrer Herstellung
US4237128A (en) * 1979-04-12 1980-12-02 E. R. Squibb & Sons, Inc. 7-[2-(2-Amino-4-thiazolyl)-2-[(1-carboxy-1,1-dialkyl)alkoxyimino]acetamido]cephem sulfoxides
GR75644B (fr) * 1980-06-18 1984-08-02 Fujisawa Pharmaceutical Co

Also Published As

Publication number Publication date
ZA821365B (en) 1983-01-26
NZ199875A (en) 1985-04-30
GR74749B (fr) 1984-07-11
IE820463L (en) 1982-09-03
DE3269543D1 (en) 1986-04-10
AU559122B2 (en) 1987-02-26
EP0060745A3 (en) 1983-08-31
IL65110A0 (en) 1982-04-30
PT74511B (fr) 1983-11-08
AU8106182A (en) 1982-09-09
FI73441C (fi) 1987-10-09
DK88382A (da) 1982-09-04
JPS57158791A (en) 1982-09-30
ES510068A0 (es) 1983-04-01
CA1191838A (fr) 1985-08-13
FI820736L (fi) 1982-09-04
IE52767B1 (en) 1988-02-17
NO820649L (no) 1982-09-06
IL65110A (en) 1985-02-28
ES8305371A1 (es) 1983-04-01
PT74511A (fr) 1982-04-01
FI73441B (fi) 1987-06-30
EP0060745A2 (fr) 1982-09-22
FR2501209A1 (fr) 1982-09-10
EP0060745B1 (fr) 1986-03-05
ATE18403T1 (de) 1986-03-15
US4476123A (en) 1984-10-09

Similar Documents

Publication Publication Date Title
FR2501209B1 (fr) Nouveaux derives des cephalosporines et medicaments antibiotiques contenant lesdits derives
FR2479229B1 (fr) Nouveaux derives des cephalosporines, leur procede de preparation et les medicaments utilisables comme antibiotiques qui contiennent lesdits derives
PT75854A (fr) Procede de preparation de nouveaux derives de pyridinium thiomethyl cephalosporines
GB1429539A (en) Derivatives of penam-3-carboxylic acid and cephem-4-carboxylic acid and processes for their manufacture
ATE54148T1 (de) Neue cephalosporine und verfahren zu ihrer herstellung.
DE3265901D1 (en) Cephalosporin derivatives substituted in position 3 with a thiomethylheterocyclic group, process for their preparation and pharmaceutical compositions containing them
BE781659A (fr) Procede de preparation de nouveaux derives de l'ester d'acyloxyalcoyle de la penicilline et de la cephalosporine
MA19841A1 (fr) Procede de preparation de nouveaux derives de cephalosporines utilisables comme antibiotiques .
GB1430908A (en) Derivatives of cephalosporin
PT74952B (fr) Procede de preparation de derives heterocycliques d'amidoximes et de compositions pharmaceutiques les contenant
FR2418800A1 (fr) Nouvelles cephalosporines et leur procede de preparation
BE811798A (fr) Nouveaux acides et derives d'acides penicillaniques et cephalosporaniques
ES2002912A6 (es) Procedimiento para la produccion de antibioticos de cefalosporina
JPS5492982A (en) Dipeptide-type cephem derivative
FR2365571A1 (fr) Acides 7-acylamino-3-(sulfomethylthiadiazolyl- ou triazolyl-thiomethyl)-3-cepheme-4-carboxyliques, leur procede de preparation et leur application en therapeutique

Legal Events

Date Code Title Description
ST Notification of lapse