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FR2549054B1 - 1-phenoxy-3-hydroxyindolylalkylamino-2-propanols, leur preparation et leur application pharmacologique - Google Patents

1-phenoxy-3-hydroxyindolylalkylamino-2-propanols, leur preparation et leur application pharmacologique

Info

Publication number
FR2549054B1
FR2549054B1 FR8408858A FR8408858A FR2549054B1 FR 2549054 B1 FR2549054 B1 FR 2549054B1 FR 8408858 A FR8408858 A FR 8408858A FR 8408858 A FR8408858 A FR 8408858A FR 2549054 B1 FR2549054 B1 FR 2549054B1
Authority
FR
France
Prior art keywords
hydroxyindolylalkylamino
propanols
phenoxy
preparation
pharmacological application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8408858A
Other languages
English (en)
Other versions
FR2549054A1 (fr
Inventor
William E Kreighbaum
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FR2549054A1 publication Critical patent/FR2549054A1/fr
Application granted granted Critical
Publication of FR2549054B1 publication Critical patent/FR2549054B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8408858A 1983-06-10 1984-06-06 1-phenoxy-3-hydroxyindolylalkylamino-2-propanols, leur preparation et leur application pharmacologique Expired FR2549054B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50290183A 1983-06-10 1983-06-10

Publications (2)

Publication Number Publication Date
FR2549054A1 FR2549054A1 (fr) 1985-01-18
FR2549054B1 true FR2549054B1 (fr) 1988-03-04

Family

ID=23999880

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8408858A Expired FR2549054B1 (fr) 1983-06-10 1984-06-06 1-phenoxy-3-hydroxyindolylalkylamino-2-propanols, leur preparation et leur application pharmacologique

Country Status (29)

Country Link
JP (1) JPS608262A (fr)
KR (1) KR900005021B1 (fr)
AT (1) AT381492B (fr)
AU (1) AU569303B2 (fr)
BE (1) BE899875A (fr)
CA (1) CA1217496A (fr)
CH (1) CH662561A5 (fr)
CY (1) CY1518A (fr)
DE (1) DE3421252A1 (fr)
DK (1) DK162089C (fr)
ES (1) ES8507490A1 (fr)
FI (1) FI78291C (fr)
FR (1) FR2549054B1 (fr)
GB (1) GB2141121B (fr)
GR (1) GR82208B (fr)
HK (1) HK14690A (fr)
HU (1) HU191670B (fr)
IE (1) IE57682B1 (fr)
IL (1) IL72008A (fr)
IT (1) IT1206705B (fr)
LU (1) LU85410A1 (fr)
MY (1) MY102077A (fr)
NL (1) NL8401840A (fr)
NO (1) NO164471C (fr)
NZ (1) NZ208337A (fr)
SE (1) SE455865B (fr)
SG (1) SG1090G (fr)
YU (1) YU44873B (fr)
ZA (1) ZA844277B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601008B1 (fr) * 1986-07-03 1990-03-30 Sanofi Sa Procede de synthese stereospecifique de derives de l'indole
KR101986648B1 (ko) 2018-04-06 2019-06-07 (유)로뎀건설 강관작업구 굴착장치

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES259580A1 (es) * 1959-07-13 1961-01-16 Philips Nv Procedimiento para la preparacion de nuevas indolietilaminas farmacologicamente activas
NL300886A (fr) * 1962-11-23
CA1116598A (fr) * 1977-07-13 1982-01-19 William T. Comer 3-indolyl-butylaminopropanols tertiaires
US4314943A (en) * 1977-07-13 1982-02-09 Mead Johnson & Company Heterocyclic substituted aryloxy 3-indolyl-tertiary butylaminopropanols
US4234595A (en) * 1977-07-13 1980-11-18 Mead Johnson & Company 3-Indolyl-tertiary butylaminopropanols
FR2463765A1 (fr) * 1979-08-17 1981-02-27 Clin Midy Nouveaux derives de l'indole actifs sur le systeme cardiovasculaire

Also Published As

Publication number Publication date
CA1217496A (fr) 1987-02-03
JPH0587503B2 (fr) 1993-12-16
NO164471C (no) 1990-10-10
IL72008A0 (en) 1984-10-31
FR2549054A1 (fr) 1985-01-18
DE3421252A1 (de) 1984-12-13
IE841441L (en) 1984-12-10
DK162089C (da) 1992-02-24
AU2923884A (en) 1984-12-13
HU191670B (en) 1987-03-30
IL72008A (en) 1988-05-31
DK162089B (da) 1991-09-16
NL8401840A (nl) 1985-01-02
FI78291B (fi) 1989-03-31
YU99784A (en) 1986-10-31
BE899875A (fr) 1984-12-10
IT1206705B (it) 1989-04-27
FI842316A0 (fi) 1984-06-07
MY102077A (en) 1992-03-31
AU569303B2 (en) 1988-01-28
ATA186784A (de) 1986-03-15
CH662561A5 (de) 1987-10-15
HUT34445A (en) 1985-03-28
SE455865B (sv) 1988-08-15
SE8403112L (sv) 1984-12-11
HK14690A (en) 1990-03-02
ES533185A0 (es) 1985-09-16
SG1090G (en) 1990-07-06
JPS608262A (ja) 1985-01-17
DK284184D0 (da) 1984-06-08
ES8507490A1 (es) 1985-09-16
IE57682B1 (en) 1993-02-24
GR82208B (fr) 1984-12-13
ZA844277B (en) 1985-03-27
CY1518A (en) 1990-11-16
IT8421330A0 (it) 1984-06-08
NO842279L (no) 1984-12-11
KR850000396A (ko) 1985-02-27
FI842316A (fi) 1984-12-11
NZ208337A (en) 1988-10-28
GB2141121A (en) 1984-12-12
LU85410A1 (fr) 1985-03-26
NO164471B (no) 1990-07-02
SE8403112D0 (sv) 1984-06-08
GB2141121B (en) 1987-01-07
FI78291C (fi) 1989-07-10
KR900005021B1 (ko) 1990-07-18
YU44873B (en) 1991-04-30
DK284184A (da) 1984-12-11
GB8414652D0 (en) 1984-07-11
AT381492B (de) 1986-10-27

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Legal Events

Date Code Title Description
ER Errata listed in the french official journal (bopi)

Free format text: 3/85

ST Notification of lapse