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FR2431505A1 - Nouveaux n-(diaminophosphinyl)arylcarboxamides, utiles notamment comme inhibiteurs de l'urease - Google Patents

Nouveaux n-(diaminophosphinyl)arylcarboxamides, utiles notamment comme inhibiteurs de l'urease

Info

Publication number
FR2431505A1
FR2431505A1 FR7918733A FR7918733A FR2431505A1 FR 2431505 A1 FR2431505 A1 FR 2431505A1 FR 7918733 A FR7918733 A FR 7918733A FR 7918733 A FR7918733 A FR 7918733A FR 2431505 A1 FR2431505 A1 FR 2431505A1
Authority
FR
France
Prior art keywords
diaminophosphinyl
arylcarboxamides
novel
useful
urease inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7918733A
Other languages
English (en)
Other versions
FR2431505B1 (fr
Inventor
Allan V Bayless
Ozra E Millner Jr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ATK Launch Systems LLC
Original Assignee
Morton Norwich Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Morton Norwich Products Inc filed Critical Morton Norwich Products Inc
Publication of FR2431505A1 publication Critical patent/FR2431505A1/fr
Application granted granted Critical
Publication of FR2431505B1 publication Critical patent/FR2431505B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/22Amides of acids of phosphorus
    • C07F9/26Amides of acids of phosphorus containing P-halide groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/22Amides of acids of phosphorus
    • C07F9/224Phosphorus triamides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576Six-membered rings
    • C07F9/58Pyridine rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Les médicaments selon l'invention sont de nouveaux N-Ødiaminophosphinylõarylcarboxamides de formule générale :
FR7918733A 1978-07-19 1979-07-19 Nouveaux n-(diaminophosphinyl)arylcarboxamides, utiles notamment comme inhibiteurs de l'urease Granted FR2431505A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/925,968 US4182881A (en) 1978-07-19 1978-07-19 N-[Diaminophosphinyl]arylcarboxamides

Publications (2)

Publication Number Publication Date
FR2431505A1 true FR2431505A1 (fr) 1980-02-15
FR2431505B1 FR2431505B1 (fr) 1984-07-13

Family

ID=25452508

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7918733A Granted FR2431505A1 (fr) 1978-07-19 1979-07-19 Nouveaux n-(diaminophosphinyl)arylcarboxamides, utiles notamment comme inhibiteurs de l'urease

Country Status (15)

Country Link
US (1) US4182881A (fr)
JP (1) JPS5515461A (fr)
AU (1) AU521741B2 (fr)
BE (1) BE877737A (fr)
CA (1) CA1125289A (fr)
CH (1) CH642084A5 (fr)
DE (1) DE2928831C2 (fr)
ES (1) ES482598A1 (fr)
FR (1) FR2431505A1 (fr)
GB (1) GB2025974B (fr)
IE (1) IE48326B1 (fr)
IT (1) IT1120421B (fr)
MX (1) MX5375E (fr)
NL (1) NL190781C (fr)
SE (1) SE441831B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2514768A1 (fr) * 1981-10-19 1983-04-22 Eisai Co Ltd Derives de phosphoramide, leur procede de preparation et leur application en therapeutique

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4539037A (en) * 1983-03-16 1985-09-03 Allied Corporation Urease inhibited urea based fertilizer compositions containing N-aryl-N-aliphatic phosphorotriamide compounds
EP0119494A1 (fr) * 1983-03-16 1984-09-26 Allied Corporation Compositions d'engrais à base d'urée inhibée contre l'uréase, contenant des composés phosphorés
US4517002A (en) * 1983-03-16 1985-05-14 Allied Corporation Phosphorodiamide urease inhibitors and urease inhibited urea based fertilizer compositions
US4530714A (en) * 1983-03-16 1985-07-23 Allied Corporation N-aliphatic and N,N-aliphatic phosphoric triamide urease inhibitors and urease inhibited urea based fertilizer compositions
US4540428A (en) * 1983-03-16 1985-09-10 Allied Corporation Phosphorotriamidate urease inhibitors and urease inhibited urea based fertilizer compositions
US4518413A (en) * 1983-06-06 1985-05-21 Allied Corporation Poly-phosphorodiamide urease inhibitors and urease inhibited urea based fertilizer compositions
US4517003A (en) * 1983-06-08 1985-05-14 Allied Corporation N-acyl phosphoric triamide urease inhibitors and urease inhibited urea based fertilizer compositions
US4517007A (en) * 1983-06-09 1985-05-14 Allied Corporation Phosphoroamide urease inhibitors and urease inhibited urea based fertilizer compositions
US4528020A (en) * 1983-06-16 1985-07-09 Allied Corporation Urease inhibited urea based fertilizer compositions
US4624695A (en) * 1983-12-20 1986-11-25 Allied Corporation O-diaminophosphinyl derivatives of oximes as urease inhibitors
US4824783A (en) * 1983-12-20 1989-04-25 Enichem S.P.A. Oxidized sulfur derivatives of diaminophosphinyl compounds as urease inhibitors
US4629491A (en) * 1983-12-20 1986-12-16 Allied Corporation Oxidized sulfur derivatives of diaminophosphinyl compounds as urease inhibitors and urease inhibited urea based fertilizer compositions
US4800194A (en) * 1985-08-01 1989-01-24 Norwich Eaton Pharmaceuticals, Inc. Acylphosphorotriamides useful as lipid-altering agents
US4668667A (en) * 1985-08-01 1987-05-26 Norwich Eaton Pharmaceuticals, Inc. Acylphosphorotriamides useful as lipid-altering agents
CA2228953A1 (fr) * 1995-09-26 1997-04-03 Takeda Chemical Industries, Ltd. Phosphorylamides, leur preparation et leur utilisation
AU6422798A (en) * 1997-03-25 1998-10-20 Takeda Chemical Industries Ltd. Stabilized urease inhibitor
DE10118322A1 (de) * 2001-04-12 2002-10-17 Piesteritz Stickstoff Heterozyklisch-substituierte (Thio)Phosphorsäuretriamide, Verfahren zu ihrer Herstellung und deren Verwendung als Mittel zur Regulierung bzw.Hemmung der enzymatischen Harnstoff-Hydrolyse
EP2859039A2 (fr) 2012-06-08 2015-04-15 Basf Se Superabsorbant limitant les odeurs
DE102013012500A1 (de) 2013-07-26 2015-01-29 Skw Stickstoffwerke Piesteritz Gmbh Verwendung von Phosphorsäureamiden als Mittel zur Verbesserung der Trockenstresstoleranz

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3317637A (en) * 1961-06-30 1967-05-02 Dow Chemical Co N-haloacylphosphoric amides
US3321516A (en) * 1963-12-06 1967-05-23 Pennsalt Chemicals Corp Dialkylthiocarbamylphosphonic diamides
GB1448241A (en) * 1973-01-23 1976-09-02 Ici Ltd Thiophosphorus acid amides and their use as inhibitors of premature vulcanisation of rubber

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2514768A1 (fr) * 1981-10-19 1983-04-22 Eisai Co Ltd Derives de phosphoramide, leur procede de preparation et leur application en therapeutique

Also Published As

Publication number Publication date
NL7905138A (nl) 1980-01-22
DE2928831A1 (de) 1980-01-31
AU4676379A (en) 1980-01-24
FR2431505B1 (fr) 1984-07-13
ES482598A1 (es) 1980-07-01
SE441831B (sv) 1985-11-11
US4182881A (en) 1980-01-08
JPS5515461A (en) 1980-02-02
GB2025974B (en) 1982-10-27
SE7905922L (sv) 1980-01-20
NL190781B (nl) 1994-03-16
CA1125289A (fr) 1982-06-08
MX5375E (es) 1983-06-30
GB2025974A (en) 1980-01-30
IT1120421B (it) 1986-03-26
BE877737A (fr) 1980-01-16
IT7949148A0 (it) 1979-05-23
CH642084A5 (de) 1984-03-30
NL190781C (nl) 1994-08-16
DE2928831C2 (de) 1986-10-09
AU521741B2 (en) 1982-04-29
JPS6254117B2 (fr) 1987-11-13
IE790790L (en) 1980-01-19
IE48326B1 (en) 1984-12-12

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