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FR2430234A1 - Antitumour compsn. contg. Panax saponin - esp. from Panax ginseng - Google Patents

Antitumour compsn. contg. Panax saponin - esp. from Panax ginseng

Info

Publication number
FR2430234A1
FR2430234A1 FR7819902A FR7819902A FR2430234A1 FR 2430234 A1 FR2430234 A1 FR 2430234A1 FR 7819902 A FR7819902 A FR 7819902A FR 7819902 A FR7819902 A FR 7819902A FR 2430234 A1 FR2430234 A1 FR 2430234A1
Authority
FR
France
Prior art keywords
right arrow
panax
esp
antitumour
compsn
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7819902A
Other languages
French (fr)
Other versions
FR2430234B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE19782828851 priority Critical patent/DE2828851A1/en
Application filed by Individual filed Critical Individual
Priority to FR7819902A priority patent/FR2430234A1/en
Publication of FR2430234A1 publication Critical patent/FR2430234A1/en
Application granted granted Critical
Publication of FR2430234B1 publication Critical patent/FR2430234B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J17/005—Glycosides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/256—Polyterpene radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Steroid Compounds (AREA)

Abstract

Antitumour compsn. contains as active ingredient a saponin substance from the underground parts of plants of the genus Panax (Araliaceae), pref. P. japonicum, P. quinquefolium, P. pseudoginseng, P. notoginseng or esp. P. ginseng. Esp. the active ingredients are of formulae (I) or (II): (where R1 is Q-(1 right arrow 2)-Q-; R2 is Q-(1 right arrow 6)-Q-, alpha-L-arabinopyranosyl-(1 right arrow 6)-Q-, alpha-D-xylopyranosyl-(1 right arrow 6)-Q-, L-arabinofuranosyl-(1 right arrow 6)-Q- or Q-; Q is beta-D-glucopyranosyl; R3 is alpha-L-rhamnopyranosyl-(1 right arrow 2)-Q-, Q-(1 right arrow 2)-Q-, Q- or pyranosyl; R5 is H or Q). The extracts are useful in human and veterinary medicine against tumours. They have no side effects and very low toxicity.
FR7819902A 1978-06-30 1978-07-04 Antitumour compsn. contg. Panax saponin - esp. from Panax ginseng Granted FR2430234A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DE19782828851 DE2828851A1 (en) 1978-06-30 1978-06-30 NEW ANTITUARY AGENTS
FR7819902A FR2430234A1 (en) 1978-06-30 1978-07-04 Antitumour compsn. contg. Panax saponin - esp. from Panax ginseng

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19782828851 DE2828851A1 (en) 1978-06-30 1978-06-30 NEW ANTITUARY AGENTS
FR7819902A FR2430234A1 (en) 1978-06-30 1978-07-04 Antitumour compsn. contg. Panax saponin - esp. from Panax ginseng

Publications (2)

Publication Number Publication Date
FR2430234A1 true FR2430234A1 (en) 1980-02-01
FR2430234B1 FR2430234B1 (en) 1980-12-26

Family

ID=25774868

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7819902A Granted FR2430234A1 (en) 1978-06-30 1978-07-04 Antitumour compsn. contg. Panax saponin - esp. from Panax ginseng

Country Status (2)

Country Link
DE (1) DE2828851A1 (en)
FR (1) FR2430234A1 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0030444A2 (en) * 1979-12-03 1981-06-17 Kitasato Kenkyusho A process for preparing substances having interferon inducing activity
FR2531864A1 (en) * 1982-08-23 1984-02-24 Tsumura Juntendo Kk ADMINICULUM FOR ANTI-TUMOR AGENTS COMPRISING AN EXTRACT FROM A RAW PHARMACEUTICAL PRODUCT INCLUDING ASTRAGALI RADIX
WO2003103682A1 (en) * 2002-06-11 2003-12-18 Panagin Pharmaceuticals Inc. Compositions for cancer therapy saponins or sapogenins
CN100441190C (en) * 2002-06-11 2008-12-10 博新药业有限公司 Protopanaxadiol and protopanaxatriol and their use as anti-cancer agents

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4339442A (en) * 1980-03-11 1982-07-13 Tsunematsu Takemoto Gynosaponins, their use and a process for preparing the same
JP4773512B2 (en) * 2005-04-26 2011-09-14 コ，ブン−キョン Extraction method of ginseng saponin Rg2, pharmaceutical composition containing the extract and use thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2354777A1 (en) * 1976-06-03 1978-01-13 Inverni Della Beffa Spa PHARMACEUTICAL COMPOSITIONS CONTAINING A PURIFIED EXTRACT OF GINSENG ROOTS AND PROCESS FOR THE PREPARATION OF SUCH EXTRACT.

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2354777A1 (en) * 1976-06-03 1978-01-13 Inverni Della Beffa Spa PHARMACEUTICAL COMPOSITIONS CONTAINING A PURIFIED EXTRACT OF GINSENG ROOTS AND PROCESS FOR THE PREPARATION OF SUCH EXTRACT.

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CA1968 *
CA1971 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0030444A2 (en) * 1979-12-03 1981-06-17 Kitasato Kenkyusho A process for preparing substances having interferon inducing activity
EP0030444B1 (en) * 1979-12-03 1985-01-30 Kitasato Kenkyusho A process for preparing substances having interferon inducing activity
FR2531864A1 (en) * 1982-08-23 1984-02-24 Tsumura Juntendo Kk ADMINICULUM FOR ANTI-TUMOR AGENTS COMPRISING AN EXTRACT FROM A RAW PHARMACEUTICAL PRODUCT INCLUDING ASTRAGALI RADIX
WO2003103682A1 (en) * 2002-06-11 2003-12-18 Panagin Pharmaceuticals Inc. Compositions for cancer therapy saponins or sapogenins
CN100441190C (en) * 2002-06-11 2008-12-10 博新药业有限公司 Protopanaxadiol and protopanaxatriol and their use as anti-cancer agents

Also Published As

Publication number Publication date
FR2430234B1 (en) 1980-12-26
DE2828851A1 (en) 1980-01-10

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Legal Events

Date Code Title Description
ST Notification of lapse