[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

FR2413390A1 - Composes de type pyrido-pyrimidine utiles comme anti-allergiques et procede pour leur preparation - Google Patents

Composes de type pyrido-pyrimidine utiles comme anti-allergiques et procede pour leur preparation

Info

Publication number
FR2413390A1
FR2413390A1 FR7836462A FR7836462A FR2413390A1 FR 2413390 A1 FR2413390 A1 FR 2413390A1 FR 7836462 A FR7836462 A FR 7836462A FR 7836462 A FR7836462 A FR 7836462A FR 2413390 A1 FR2413390 A1 FR 2413390A1
Authority
FR
France
Prior art keywords
alkyl
compounds
hydrogen
alcoyl
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7836462A
Other languages
English (en)
Other versions
FR2413390B1 (fr
Inventor
Istvan Hermecz
Zoltan Meszaros
Tibor Breining
Sandor Virag
Lelle Vasvari
Agnes Horvath
Gabor Nagy
Attila Mandi
Tamas Szuts
Istvan Bitter
Gyula Sebestyen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chinoin Private Co Ltd
Original Assignee
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt filed Critical Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Publication of FR2413390A1 publication Critical patent/FR2413390A1/fr
Application granted granted Critical
Publication of FR2413390B1 publication Critical patent/FR2413390B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

L'INVENTION CONCERNE DES COMPOSES CHIMIQUES NOUVEAUX. IL S'AGIT DE DERIVES CONDENSES DE PYRIMIDINE A TETE DE PONT D'AZOTE DE LA FORMULE GENERALE: (CF DESSIN DANS BOPI) OU R REPRESENTE NOTAMMENT L'HYDROGENE OU UN GROUPE ALCOYLE; R REPRESENTE DE L'HYDROGENE OU UN GROUPE ALCOYLE, STYRYLE, CARBOXY OU DERIVE; R REPRESENTE L'HYDROGENE, UN GROUPE ALCOYLE OU HYDROXY; R REPRESENTE L'HYDROGENE, UN GROUPE ALCOYLE, ARYLE, ALCANOYLE, CARBOXY OU DERIVE OU -(CH)-COOH; M1, 2 OU 3; R EST NOTAMMENT DE L'HYDROGENE, UN GROUPE ALCOYLE, TRIFLUOROMETHYLE, ARYLE, PHENYL-ALCOYLE OU UN HETEROCYCLE; R EST DE L'HYDROGENE, UN GROUPE ALCOYLE, ARYLE, PHENYL-ALCOYLE, ALCANOYLE, HETEROARYLE OU BENZOYLE; N1. CES COMPOSES SONT UTILES COMME MEDICAMENTS.
FR7836462A 1977-12-29 1978-12-27 Composes de type pyrido-pyrimidine utiles comme anti-allergiques et procede pour leur preparation Granted FR2413390A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU77CI1795A HU180439B (en) 1977-12-29 1977-12-29 Process for producing 9-amino-pyrido-square bracket-1,2-a-square bracket closed-pyrimidine derivatives

Publications (2)

Publication Number Publication Date
FR2413390A1 true FR2413390A1 (fr) 1979-07-27
FR2413390B1 FR2413390B1 (fr) 1982-06-11

Family

ID=10994684

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7836462A Granted FR2413390A1 (fr) 1977-12-29 1978-12-27 Composes de type pyrido-pyrimidine utiles comme anti-allergiques et procede pour leur preparation

Country Status (28)

Country Link
US (1) US4260612A (fr)
JP (1) JPS54112895A (fr)
AR (1) AR221712A1 (fr)
AT (1) AT374476B (fr)
AU (1) AU520803B2 (fr)
BE (1) BE873141A (fr)
CA (1) CA1154766A (fr)
CH (1) CH641800A5 (fr)
CS (1) CS241014B2 (fr)
DD (1) DD143910A5 (fr)
DE (1) DE2854112A1 (fr)
DK (1) DK585478A (fr)
ES (1) ES476837A1 (fr)
FI (1) FI65620C (fr)
FR (1) FR2413390A1 (fr)
GB (1) GB2011408B (fr)
GR (1) GR67312B (fr)
HU (1) HU180439B (fr)
IL (1) IL56132A (fr)
IT (1) IT7869932A0 (fr)
LU (1) LU80659A1 (fr)
NL (1) NL7812479A (fr)
NO (1) NO150280C (fr)
PL (1) PL119517B1 (fr)
PT (1) PT68924A (fr)
SE (1) SE434056B (fr)
SU (1) SU906379A3 (fr)
YU (2) YU296378A (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU178452B (en) * 1979-05-11 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 9-substituted amino-4-oxo-6,7-dihydro-4h-pyrido/1,2-a/pyrimidine derivatives
HU183330B (en) * 1981-02-13 1984-04-28 Chinoin Gyogyszer Es Vegyeszet Process for producing new of 2,4,8-triazaphenalenium-salts
US5352795A (en) * 1986-03-07 1994-10-04 Ciba-Geigy Corporation Alpha-heterocycle substituted tolunitriles
US5252572A (en) * 1988-02-03 1993-10-12 Chinoin Gyogyszer- Es Vegyeszeti Termekek Gyara Rt. Pyridopyrimidine derivatives, pharmaceutical compositions containing them and process for preparing same
HU201551B (en) * 1988-02-03 1990-11-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 4-oxo-4h-pyrido(1,2-a)pyrimidine-3-carboxylic acid amide derivatives and pharmaceutical compositions comprising same

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR7813M (fr) * 1966-11-02 1970-05-20
JPS50149698A (fr) * 1974-05-25 1975-11-29

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2786056A (en) * 1954-05-03 1957-03-19 Merck & Co Inc Acylamido-hydroxy pteridines and preparation thereof
GB1147760A (en) * 1965-06-17 1969-04-10 Sterling Drug Inc Heterocyclic nitrogen compounds
GB1141249A (en) * 1967-05-25 1969-01-29 Parke Davis & Co New quinazoline compounds and methods for their production
US3642797A (en) * 1968-06-10 1972-02-15 Sterling Drug Inc 4h-pyrido(1 2-a)pyrimidin-4-ones
HU174693B (hu) * 1976-02-12 1980-03-28 Chinoin Gyogyszer Es Vegyeszet Sposob poluchenija kondensirovannykh proizvodnykh pirimidina
US4122274A (en) * 1977-05-25 1978-10-24 Bristol-Myers Company 3-Tetrazolo-5,6,7,8-substituted-pyrido[1,2-a]pyrimidin-4-ones

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR7813M (fr) * 1966-11-02 1970-05-20
GB1209946A (en) * 1966-11-02 1970-10-21 Chinoin Gyogyszer Es Vegyeszet Homopyrimidazole derivatives
JPS50149698A (fr) * 1974-05-25 1975-11-29

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CA1976 *

Also Published As

Publication number Publication date
GR67312B (fr) 1981-06-29
FI65620C (fi) 1984-06-11
SE7813225L (sv) 1979-06-30
NO150280C (no) 1984-09-19
CS909078A2 (en) 1985-06-13
CA1154766A (fr) 1983-10-04
DE2854112A1 (de) 1979-07-12
IL56132A (en) 1982-02-28
GB2011408A (en) 1979-07-11
NL7812479A (nl) 1979-07-03
PL119517B1 (en) 1982-01-30
DK585478A (da) 1979-06-30
PT68924A (en) 1979-01-01
JPS54112895A (en) 1979-09-04
FI784014A (fi) 1979-06-30
HU180439B (en) 1983-03-28
ATA901078A (de) 1983-09-15
SU906379A3 (ru) 1982-02-15
FI65620B (fi) 1984-02-29
BE873141A (fr) 1979-04-17
NO784392L (no) 1979-07-02
AT374476B (de) 1984-04-25
PL212205A1 (fr) 1980-02-25
YU296378A (en) 1983-10-31
GB2011408B (en) 1982-06-30
ES476837A1 (es) 1979-06-16
YU278082A (en) 1983-10-31
CS241014B2 (en) 1986-03-13
AU520803B2 (en) 1982-02-25
CH641800A5 (de) 1984-03-15
DD143910A5 (de) 1980-09-17
NO150280B (no) 1984-06-12
US4260612A (en) 1981-04-07
AR221712A1 (es) 1981-03-13
SE434056B (sv) 1984-07-02
IL56132A0 (en) 1979-03-12
AU4262878A (en) 1981-06-18
FR2413390B1 (fr) 1982-06-11
IT7869932A0 (it) 1978-12-22
LU80659A1 (de) 1979-04-13

Similar Documents

Publication Publication Date Title
FR2378023A1 (fr) Procede de preparation d'oximes, nouveaux produits ainsi obtenus et leur application dans la synthese de composes d'acide cephemcarboxylique 3,7-disubstitue
FR2416889A1 (fr) Derives esters de l'acide dihydro-1,4-pyridine-dicarboxylique-3,5, medicaments a base de ces derives et leur procede de production
FR2413389A1 (fr) Composes a tete de pont azotee ayant une action anti-allergique et procede pour leur preparation
FR2374334A1 (fr) Nouveaux nucleosides utiles comme medicaments et procede pour leur preparation
FR2372818A1 (fr) Acide 5-(hydroxy (substitue) methyl)-2,3-dihydrobenzofuran-2-carboxylique et ses derives utiles comme medicaments
FR2448531A1 (fr) Nouveaux derives de 4-(naphtylmethyl)piperidine, utiles notamment comme agents antipsychotiques et leur procede de preparation
FR2435479A1 (fr) Procede de preparation de composes d'acide 3-cephem-4-carboxylique 3, 7-disubstitue et de leurs sels pharmaceutiquement acceptables, nouveaux produits ainsi obtenus et leur utilisation pour leurs activites antimicrobiennes
FR2408584A1 (fr) Composes guanidinobenzoiques et possedant une activite antifibrinolysine et antitrypsine et leur procede de preparation
FR2394546A1 (fr) Nouveaux derives de 1,2,3,4,6,7-hexahydro-11bah-benzo(a)-quinolizine, leur preparation et leur application en tant que medicaments
FR2452486A1 (fr) Nouveaux derives d'a-(3,4-dichlorophenyl)-imidazoline ou pyrimidine-2-methane utiles notamment comme agents antisecretoires et leur procede de preparation
KR900003499B1 (ko) 퀴놀린계 화합물, 그의 제조방법 및 그 화합물을 약효성분으로 함유하는 항암제
CA2079548A1 (fr) Derives carbamate de 4-amino-3-isoxazolidinones, 3-amino-1-hydroxypyrrolidin-2-ones et d'analogues de l'acide 1-amino-1-cyclopropanecarboxylique, procede pour leur preparation, etleur utilisation en tant que medicaments
FR2407928A1 (fr) Derives de quinazoline utiles comme medicaments antihypertenseurs et procede de leur preparation
FR2413390A1 (fr) Composes de type pyrido-pyrimidine utiles comme anti-allergiques et procede pour leur preparation
FR2450820A1 (fr) Nouveaux derives d'acides 1- (o-mercaptoacyl) -4,5-dihydropyrazole-5-carboxyliques, utiles notamment comme agents hypotenseurs, et leur procede de preparation
FR2363608A1 (fr) Procede de preparation de colorants " bisazoiques "
FR2452483A1 (fr) Derives d'alcenylphenylmaleimides, leurs dimeres lineaires et leur procede de preparation
FR2366285A1 (fr) (3-amino-5-substitue-6-fluoropyrazinoyl ou pyrazamido) guanidines et leurs derives portant des substituants sur les atomes d'azote du noyau de guanidine, utiles comme medicaments
KR900006722B1 (ko) 항불안제
FR2457867A1 (fr) Nouveaux derives d'hydroxyamino-eburnane : leur procede de preparation, intermediaires utilises et utilisation comme medicament et comme intermediaire
FR2413358A1 (fr) Nouveaux derives de 2-aminomethylphenol, utiles notamment comme agents anti-inflammatoires, et leur procede de preparation
FR2506313A1 (fr) Derives de l'acide n-acetylneuraminique et leur preparation
ES8103069A1 (es) Procedimiento para la preparacion de derivados de tiazolina
JPH0640989A (ja) 新規化合物
EP0124379B1 (fr) Dérivés d'hydroquinone et procédé pour leur production

Legal Events

Date Code Title Description
ST Notification of lapse