[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

FR2320085A1 - Anthracyclinones optiquement actives et leur procede de preparation - Google Patents

Anthracyclinones optiquement actives et leur procede de preparation

Info

Publication number
FR2320085A1
FR2320085A1 FR7628763A FR7628763A FR2320085A1 FR 2320085 A1 FR2320085 A1 FR 2320085A1 FR 7628763 A FR7628763 A FR 7628763A FR 7628763 A FR7628763 A FR 7628763A FR 2320085 A1 FR2320085 A1 FR 2320085A1
Authority
FR
France
Prior art keywords
preparation process
optically active
anthracyclinones
active anthracyclinones
optically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7628763A
Other languages
English (en)
Other versions
FR2320085B1 (fr
Inventor
Federico Arcamone
Luigi Bernardi
Bianca Patelli
Aurelio Di Marco
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmaceutici Italia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia SpA filed Critical Farmaceutici Italia SpA
Publication of FR2320085A1 publication Critical patent/FR2320085A1/fr
Application granted granted Critical
Publication of FR2320085B1 publication Critical patent/FR2320085B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FR7628763A 1975-01-22 1976-09-24 Anthracyclinones optiquement actives et leur procede de preparation Granted FR2320085A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2691/75A GB1500421A (en) 1975-01-22 1975-01-22 Optically active anthracyclinones

Publications (2)

Publication Number Publication Date
FR2320085A1 true FR2320085A1 (fr) 1977-03-04
FR2320085B1 FR2320085B1 (fr) 1978-11-03

Family

ID=9744103

Family Applications (4)

Application Number Title Priority Date Filing Date
FR7601535A Granted FR2320105A1 (fr) 1975-01-22 1976-01-21 Daunomycines derivees d'anthracyclinones optiquement actives et leur procede de preparation
FR7628763A Granted FR2320085A1 (fr) 1975-01-22 1976-09-24 Anthracyclinones optiquement actives et leur procede de preparation
FR7628764A Granted FR2320086A1 (fr) 1975-01-22 1976-09-24 Nouvelles anthracyclinones optiquement actives et leur procede de preparation
FR7628762A Granted FR2333769A1 (fr) 1975-01-22 1976-09-24 Procede pour le dedoublement optique de la 1,4-dimethoxy-6-hydroxy-6-acetyl-tetraline

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR7601535A Granted FR2320105A1 (fr) 1975-01-22 1976-01-21 Daunomycines derivees d'anthracyclinones optiquement actives et leur procede de preparation

Family Applications After (2)

Application Number Title Priority Date Filing Date
FR7628764A Granted FR2320086A1 (fr) 1975-01-22 1976-09-24 Nouvelles anthracyclinones optiquement actives et leur procede de preparation
FR7628762A Granted FR2333769A1 (fr) 1975-01-22 1976-09-24 Procede pour le dedoublement optique de la 1,4-dimethoxy-6-hydroxy-6-acetyl-tetraline

Country Status (18)

Country Link
US (1) US4077988A (fr)
JP (4) JPS6033819B2 (fr)
AT (1) AT342035B (fr)
AU (1) AU500067B2 (fr)
BE (1) BE837756A (fr)
CA (1) CA1064920A (fr)
CH (3) CH622486A5 (fr)
DE (2) DE2601785C2 (fr)
DK (1) DK155518C (fr)
ES (1) ES444494A1 (fr)
FR (4) FR2320105A1 (fr)
GB (1) GB1500421A (fr)
HK (1) HK1082A (fr)
MX (1) MX4278E (fr)
NL (1) NL179724C (fr)
SE (4) SE435498B (fr)
SU (5) SU683613A3 (fr)
ZA (1) ZA76292B (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4070382A (en) * 1975-11-18 1978-01-24 Research Corporation Intermediates for polycyclic quinoid antibiotics
GB1527050A (en) * 1976-06-19 1978-10-04 Farmaceutici Italia Optically active anthracyclinones
US4134903A (en) * 1976-08-07 1979-01-16 Societa Farmaceutici Italia S.P.A. Anthracycline ethers and their preparation
GB1573036A (en) * 1977-05-05 1980-08-13 Farmaceutici Italia Anthracyclines
GB1573037A (en) * 1977-05-05 1980-08-13 Farmaceutici Italia Anthracyclines
US4296105A (en) * 1978-08-03 1981-10-20 Institut International De Pathologie Cellulaire Et Moleculaire Derivatives of doxorubicine, their preparation and use
NL8001417A (nl) * 1979-03-17 1980-09-19 Erba Farmitalia Antitumorglycosiden.
US4259476A (en) * 1979-04-02 1981-03-31 Kende Andrew S Novel heterocyclic anthracycline compounds
GB2056443B (en) * 1979-08-20 1984-01-18 Hoffmann La Roche Cyclic compounds
JPS5673039A (en) * 1979-08-20 1981-06-17 Hoffmann La Roche Naphthacene derivative
GB2071084B (en) * 1980-01-22 1984-02-29 Hoffmann La Roche Polycylic compounds
JPS5756494A (en) * 1980-09-22 1982-04-05 Microbial Chem Res Found New anthracyclin derivative
ES8308301A1 (es) * 1981-07-29 1983-08-16 Sumitomo Chemical Co Un procedimiento para la preparacion de derivados de aminonaftaceno.
BE896743A (fr) * 1982-08-13 1983-09-16 Erba Farmitalia Synthese de naphtacenequinone.
US4489206A (en) * 1983-05-13 1984-12-18 Adria Laboratories, Inc. Synthesis of (+)-4-demethoxydaunomycinone
US4831019A (en) * 1983-10-31 1989-05-16 Adria Laboratories, Inc. Pharmaceutical preparations of 4-demethoxy-n-trifluoroacetyl anthracyclines
US4496485A (en) * 1983-11-25 1985-01-29 G. D. Searle & Co. Asymmetric 7-O-(substituted acetyl)-4-demethoxydaunomycinones
GB8519452D0 (en) * 1985-08-02 1985-09-11 Erba Farmitalia Injectable solutions
KR0130906B1 (ko) * 1987-03-11 1998-04-23 팜이탈리아 카를로 에르바 에스. 알. 엘. 면역글로불린 결합체, 이의 제조방법 및 이를 포함하는 약제학적 조성물
NZ224252A (en) * 1987-04-21 1991-09-25 Erba Carlo Spa An anthracycline glycoside and its preparation
GB8803301D0 (en) * 1988-02-12 1988-03-09 Erba Carlo Spa Process for preparation of 4-demethoxy-daunomycinone aglycone of 4-demethoxy-daunorubicin
GB8824947D0 (en) * 1988-10-25 1988-11-30 Erba Carlo Spa New 4-substituted anthracyclinones & process for preparing them
NL9001834A (nl) * 1990-08-16 1992-03-16 Pharmachemie Bv Nieuwe antracyclineverbindingen met anti-tumorwerkzaamheid, nieuwe tussenverbindingen voor de bereiding van deze antracyclineverbindingen, alsmede preparaten die de aktieve antracyclineverbindingen bevatten.
GB9418260D0 (en) * 1994-09-09 1994-10-26 Erba Carlo Spa Anthracycline derivatives
IT1317106B1 (it) * 2000-11-16 2003-05-26 Menarini Ricerche Spa Processo per la sintesi di antracicline otticamente attive.
DE10155016A1 (de) * 2001-11-07 2003-05-15 Knoell Hans Forschung Ev Neue Chinon-Verbindung, Verfahren zur Herstellung und deren Verwendung

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3904632A (en) * 1972-05-08 1975-09-09 Hoffmann La Roche (')-di-o-isopropylidene-2-keto-l-gulonates
JPS5840556A (ja) * 1981-09-04 1983-03-09 Ricoh Co Ltd 電子写真圧力定着転写紙及びその転写紙用原紙の製造法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Also Published As

Publication number Publication date
SE8201013L (sv) 1982-02-18
SU776557A3 (ru) 1980-10-30
CH624085A5 (fr) 1981-07-15
JPS5198264A (en) 1976-08-30
AU1043276A (en) 1977-07-28
SU724087A3 (ru) 1980-03-25
BE837756A (fr) 1976-07-22
DK155518B (da) 1989-04-17
CH622486A5 (fr) 1981-04-15
FR2320086B1 (fr) 1978-11-03
SU650498A3 (ru) 1979-02-28
SU646914A3 (ru) 1979-02-05
DE2601785A1 (de) 1976-07-29
ATA30676A (de) 1977-07-15
SE461525B (sv) 1990-02-26
FR2320105B1 (fr) 1982-07-23
CA1064920A (fr) 1979-10-23
SU683613A3 (ru) 1979-08-30
ZA76292B (en) 1977-01-26
ES444494A1 (es) 1977-05-16
CH622530A5 (fr) 1981-04-15
JPS59231098A (ja) 1984-12-25
FR2333769A1 (fr) 1977-07-01
HK1082A (en) 1982-01-22
AT342035B (de) 1978-03-10
AU500067B2 (en) 1979-05-10
JPS59231038A (ja) 1984-12-25
SE435498B (sv) 1984-10-01
DE2660848C2 (de) 1986-02-06
MX4278E (es) 1982-03-11
US4077988A (en) 1978-03-07
FR2333769B1 (fr) 1979-07-06
DK20376A (da) 1976-08-02
SE453185B (sv) 1988-01-18
SE8201015L (sv) 1982-02-18
SE8201014L (sv) 1982-02-18
GB1500421A (en) 1978-02-08
NL179724C (nl) 1986-11-03
FR2320086A1 (fr) 1977-03-04
DK155518C (da) 1989-08-28
FR2320105A1 (fr) 1977-03-04
SE461529B (sv) 1990-02-26
JPS59231037A (ja) 1984-12-25
JPS6033819B2 (ja) 1985-08-05
JPH036157B2 (fr) 1991-01-29
SE7600563L (sv) 1976-07-23
FR2320085B1 (fr) 1978-11-03
DE2601785C2 (de) 1985-10-03
NL179724B (nl) 1986-06-02
NL7600075A (nl) 1976-07-26

Similar Documents

Publication Publication Date Title
BE837756A (fr) Anthracyclinones optiquement actives et leur procede de preparation
FR2299362A1 (fr) Spheres creuses et procede de leur preparation
BE849381A (fr) Compositions de blanchiment et leur procede de preparation
FR2331584A1 (fr) Poly (arylato-sulfones) et leur procede de preparation
BE845551A (fr) Acides heteroarylbenzoxepine-acetiques, leur procede de preparation et leur application
BE863872A (fr) Steroides-11 beta-substitues et procede de leur preparation
BE847090A (fr) 15-steroides, et leur procede de preparation
BE846452A (fr) Nouvelles pyrimidones, leur procede de preparation et leur applicationtherapeutique
BE854268A (fr) Pyrrolidones, leur procede de preparation et leur application therapeutique
FR2301521A1 (fr) Nouvelles n-acyl-n-norsalutaridines et leur procede de preparation
BE856220A (fr) Polyether-polyureides et procede de leur preparation
BE849504A (fr) Acides aminodi- et polyalkylamidoalcane sulfoniques, leur procede de preparation et leur utilisation
BE854812A (fr) Benzenesulfonylurees, leur procede de preparation et leur application therapeutique
BE836526A (fr) Substances actives antimicrobiennes et leur procede de preparation
FR2334658A1 (fr) Procede de preparation de phenylglycinamide optiquement actif
FR2347370A1 (fr) 7-amino-3-tetrazolyl substitue-thiomethyl-cephalosporines et leur procede de preparation
FR2299865A1 (fr) Arylmethyl-1 imidazolidones-2 et leur procede de preparation
FR2317298A1 (fr) Nouvelles lactones et leur procede de preparation
BE868027A (fr) Nouvelles pyridazinylhydrazones et leur procede de preparation
FR2333792A1 (fr) 4-hydroxymethyl-2-pyrrolidinones et leur procede de preparation
BE860773A (fr) Beta-lactames monocycliques, leur procede de preparation et leur application en therapeutique
BE849571A (fr) Diurethannes, leur procede de preparation et leur utilisation
BE862066A (fr) Agents anti-rhinovirus et procede de leur preparation
FR2329267A2 (fr) Styrylamidines et leur procede de preparation
BE828776A (fr) Combinaisons biologiquement actives et leur procede de preparation