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FR2399241A1 - Procede de deshydratation d'une dispersion colloidale de liposomes - Google Patents

Procede de deshydratation d'une dispersion colloidale de liposomes

Info

Publication number
FR2399241A1
FR2399241A1 FR7822984A FR7822984A FR2399241A1 FR 2399241 A1 FR2399241 A1 FR 2399241A1 FR 7822984 A FR7822984 A FR 7822984A FR 7822984 A FR7822984 A FR 7822984A FR 2399241 A1 FR2399241 A1 FR 2399241A1
Authority
FR
France
Prior art keywords
liposomes
dehydration
dispersion
colloidal dispersion
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7822984A
Other languages
English (en)
Other versions
FR2399241B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Battelle Memorial Institute Inc
Original Assignee
Battelle Memorial Institute Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Battelle Memorial Institute Inc filed Critical Battelle Memorial Institute Inc
Publication of FR2399241A1 publication Critical patent/FR2399241A1/fr
Application granted granted Critical
Publication of FR2399241B1 publication Critical patent/FR2399241B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention a pour objet un procédé de déshydratation d'une dispersion colloïdale de liposomes dans un milieu liquide aqueux, ce procédé ayant pour but de prolonger la durée de conservation des liposomes et de permettre leur utilisation ultérieure de façon efficace. Conformément à ce procédé, on prépare un mélange d'un composé hydrophile et de la dispersion de liposomes. On soumet ensuite ce mélange à une déshydratation servant à obtenir les liposomes sous forme d'une poudre stable permettant leur stockage prolongé et la reconstitution de la dispersion de liposomes à partir de cette poudre. L'invention s'applique notamment à l'encapsulation des substances biologiquement actives.
FR7822984A 1977-08-05 1978-08-03 Procede de deshydratation d'une dispersion colloidale de liposomes Granted FR2399241A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH961577A CH621479A5 (fr) 1977-08-05 1977-08-05

Publications (2)

Publication Number Publication Date
FR2399241A1 true FR2399241A1 (fr) 1979-03-02
FR2399241B1 FR2399241B1 (fr) 1983-02-18

Family

ID=4353829

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7822984A Granted FR2399241A1 (fr) 1977-08-05 1978-08-03 Procede de deshydratation d'une dispersion colloidale de liposomes

Country Status (17)

Country Link
US (1) US4229360A (fr)
JP (1) JPS5449317A (fr)
AU (1) AU520915B2 (fr)
BE (1) BE869551A (fr)
CA (1) CA1114714A (fr)
CH (1) CH621479A5 (fr)
DE (1) DE2834308C2 (fr)
DK (1) DK150786C (fr)
ES (1) ES472372A1 (fr)
FR (1) FR2399241A1 (fr)
GB (1) GB2002319B (fr)
IE (1) IE47165B1 (fr)
IL (1) IL55276A0 (fr)
IT (1) IT1097614B (fr)
LU (1) LU80079A1 (fr)
NL (1) NL191452C (fr)
SE (1) SE432053B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2521565A1 (fr) * 1982-02-17 1983-08-19 Dior Sa Parfums Christian Melange pulverulent de constituants lipidiques et de constituants hydrophobes, procede pour le preparer, phases lamellaires lipidiques hydratees et procede de fabrication, compositions pharmaceutiques ou cosmetiques comportant des phases lamellaires lipidiques hydratees

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JPS6121449B2 (fr) 1986-05-27
ES472372A1 (es) 1979-03-16
CA1114714A (fr) 1981-12-22
NL191452C (nl) 1995-07-18
LU80079A1 (fr) 1979-05-15
GB2002319B (en) 1982-02-24
DK345878A (da) 1979-02-06
SE432053B (sv) 1984-03-19
US4229360B1 (fr) 1991-11-05
BE869551A (fr) 1979-02-05
IT1097614B (it) 1985-08-31
IL55276A0 (en) 1978-10-31
DE2834308C2 (de) 1986-09-25
NL191452B (nl) 1995-03-16
NL7808204A (nl) 1979-02-07
CH621479A5 (fr) 1981-02-13
FR2399241B1 (fr) 1983-02-18
US4229360A (en) 1980-10-21
AU520915B2 (en) 1982-03-04
IT7826509A0 (it) 1978-08-04
IE47165B1 (en) 1984-01-11
DE2834308A1 (de) 1979-02-15
GB2002319A (en) 1979-02-21
DK150786C (da) 1988-01-25
SE7808395L (sv) 1979-02-06
JPS5449317A (en) 1979-04-18
IE781600L (en) 1979-02-07
DK150786B (da) 1987-06-22
AU3866578A (en) 1980-02-07

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