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FR2389625A1 - - Google Patents

Info

Publication number
FR2389625A1
FR2389625A1 FR7713863A FR7713863A FR2389625A1 FR 2389625 A1 FR2389625 A1 FR 2389625A1 FR 7713863 A FR7713863 A FR 7713863A FR 7713863 A FR7713863 A FR 7713863A FR 2389625 A1 FR2389625 A1 FR 2389625A1
Authority
FR
France
Prior art keywords
apovincamine
racemic
synthesis
products
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7713863A
Other languages
French (fr)
Other versions
FR2389625B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR7713863A priority Critical patent/FR2389625B1/fr
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to BE187440A priority patent/BE866756A/en
Priority to DE19782819886 priority patent/DE2819886A1/en
Priority to PT68002A priority patent/PT68002B/en
Priority to ES469477A priority patent/ES469477A1/en
Priority to IT49217/78A priority patent/IT1102526B/en
Priority to HU78RO977A priority patent/HU178713B/en
Priority to CH490478A priority patent/CH629494A5/en
Publication of FR2389625A1 publication Critical patent/FR2389625A1/fr
Application granted granted Critical
Publication of FR2389625B1 publication Critical patent/FR2389625B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A new process is described for the preparation of racemic or optically active pentacyclic products of the group of apovincaminic acid, an intermediate in the synthesis of apovincamine. Apovincamine has peripheral vasodilator properties.
FR7713863A 1977-05-06 1977-05-06 Expired FR2389625B1 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
FR7713863A FR2389625B1 (en) 1977-05-06 1977-05-06
DE19782819886 DE2819886A1 (en) 1977-05-06 1978-05-05 PROCESS FOR THE MANUFACTURE OF PENTACYCLIC RACEMIC OR OPTICALLY ACTIVE PRODUCTS OF THE APOVINCAMIC ACID GROUP
PT68002A PT68002B (en) 1977-05-06 1978-05-05 PROCESS FOR THE PREPARATION OF RACEMIC OR OPTICALLY ACTIVE PENTACYLIC PRODUCTS OF THE APOVINCAMINE ACID GROUP
ES469477A ES469477A1 (en) 1977-05-06 1978-05-05 Procedure to prepare racemic or optically active pentaciclic products of the apovincaminic acid group (Machine-translation by Google Translate, not legally binding)
BE187440A BE866756A (en) 1977-05-06 1978-05-05 PROCESS FOR THE PREPARATION OF RACEMIC OR OPTICALLY ACTIVE PENTACYCLIC PRODUCTS FROM THE APOVINCAMINIC ACID GROUP
IT49217/78A IT1102526B (en) 1977-05-06 1978-05-05 PROCEDURE FOR THE PRODUCTION OF RACEMIC OR OPTICALLY ACTIVE PENTACYCLIC PRODUCTS OF THE APOVINCAMINIC ACID GROUP
HU78RO977A HU178713B (en) 1977-05-06 1978-05-05 Process for producing raceme and optically active apovincaminic acid and salts
CH490478A CH629494A5 (en) 1977-05-06 1978-05-05 Process for the preparation of pentacyclic racemic or optically active products of the group of apovincaminic acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7713863A FR2389625B1 (en) 1977-05-06 1977-05-06

Publications (2)

Publication Number Publication Date
FR2389625A1 true FR2389625A1 (en) 1978-12-01
FR2389625B1 FR2389625B1 (en) 1980-04-18

Family

ID=9190457

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7713863A Expired FR2389625B1 (en) 1977-05-06 1977-05-06

Country Status (8)

Country Link
BE (1) BE866756A (en)
CH (1) CH629494A5 (en)
DE (1) DE2819886A1 (en)
ES (1) ES469477A1 (en)
FR (1) FR2389625B1 (en)
HU (1) HU178713B (en)
IT (1) IT1102526B (en)
PT (1) PT68002B (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2462909A1 (en) * 1979-08-16 1981-02-20 Richter Gedeon Vegyeszet DERMATOLOGICAL COMPOSITION BASED ON DERIVATIVES OF APOVINCAMINIC ACID OR APOVINCIN AND ITS DERIVATIVES FOR THE TREATMENT OF SKIN DISEASES, ACCOMPANIED BY CELLULAR PROLIFERATION, SUCH AS PSORIASIS
FR2467207A1 (en) * 1979-10-15 1981-04-17 Richter Gedeon Vegyeszet NEW HALOGEN-APOVINCAMINIC ACID ESTERS, PROCESS FOR THEIR PREPARATION AND MEDICINAL PREPARATIONS CONTAINING THEM
FR2489824A1 (en) * 1980-09-10 1982-03-12 Richter Gedeon Vegyeszet PROCESS FOR THE PREPARATION OF APOVINCAMINIC ACID ESTERS AND PRODUCTS THUS OBTAINED
FR2511677A1 (en) * 1981-08-23 1983-02-25 Richter Gedeon Vegyeszet PROCESS FOR THE PREPARATION OF ESTERS OF ALCOXYVINCAMINIC ACIDS AND ALCOXYAPOVINCAMINE
FR2529550A1 (en) * 1982-06-30 1984-01-06 Richter Gedeon Vegyeszet APOVINCAMINIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE DERIVATIVES

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU179292B (en) * 1978-12-01 1982-09-28 Richter Gedeon Vegyeszet Process for preparing ester derivatives of apovincaminic acid
HU181941B (en) * 1979-11-23 1983-11-28 Richter Gedeon Vegyeszet Process for producing apovincaminic acid ester derivatives
HU186891B (en) * 1981-06-12 1985-10-28 Richter Gedeon Vegyeszet Process for producing esters of apovincaminic acid

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2081593A1 (en) * 1970-03-31 1971-12-10 Roussel Uclaf Vincamine process

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2462909A1 (en) * 1979-08-16 1981-02-20 Richter Gedeon Vegyeszet DERMATOLOGICAL COMPOSITION BASED ON DERIVATIVES OF APOVINCAMINIC ACID OR APOVINCIN AND ITS DERIVATIVES FOR THE TREATMENT OF SKIN DISEASES, ACCOMPANIED BY CELLULAR PROLIFERATION, SUCH AS PSORIASIS
FR2467207A1 (en) * 1979-10-15 1981-04-17 Richter Gedeon Vegyeszet NEW HALOGEN-APOVINCAMINIC ACID ESTERS, PROCESS FOR THEIR PREPARATION AND MEDICINAL PREPARATIONS CONTAINING THEM
FR2489824A1 (en) * 1980-09-10 1982-03-12 Richter Gedeon Vegyeszet PROCESS FOR THE PREPARATION OF APOVINCAMINIC ACID ESTERS AND PRODUCTS THUS OBTAINED
FR2511677A1 (en) * 1981-08-23 1983-02-25 Richter Gedeon Vegyeszet PROCESS FOR THE PREPARATION OF ESTERS OF ALCOXYVINCAMINIC ACIDS AND ALCOXYAPOVINCAMINE
FR2529550A1 (en) * 1982-06-30 1984-01-06 Richter Gedeon Vegyeszet APOVINCAMINIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE DERIVATIVES

Also Published As

Publication number Publication date
HU178713B (en) 1982-06-28
IT7849217A0 (en) 1978-05-05
PT68002A (en) 1978-06-01
DE2819886A1 (en) 1978-11-09
IT1102526B (en) 1985-10-07
ES469477A1 (en) 1979-08-16
PT68002B (en) 1980-05-05
FR2389625B1 (en) 1980-04-18
BE866756A (en) 1978-11-06
DE2819886C2 (en) 1988-03-31
CH629494A5 (en) 1982-04-30

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