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FR2388793A1 - Azetidinyl-acetonitriles et -acetamides, compositions antiarythmiques contenant ces composes et utilisation de ces compositions - Google Patents

Azetidinyl-acetonitriles et -acetamides, compositions antiarythmiques contenant ces composes et utilisation de ces compositions

Info

Publication number
FR2388793A1
FR2388793A1 FR7812434A FR7812434A FR2388793A1 FR 2388793 A1 FR2388793 A1 FR 2388793A1 FR 7812434 A FR7812434 A FR 7812434A FR 7812434 A FR7812434 A FR 7812434A FR 2388793 A1 FR2388793 A1 FR 2388793A1
Authority
FR
France
Prior art keywords
compositions
acetonitriles
acetamides
azetidinyl
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7812434A
Other languages
English (en)
Other versions
FR2388793B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AH Robins Co Inc
Original Assignee
AH Robins Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AH Robins Co Inc filed Critical AH Robins Co Inc
Publication of FR2388793A1 publication Critical patent/FR2388793A1/fr
Application granted granted Critical
Publication of FR2388793B1 publication Critical patent/FR2388793B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'invention concerne de nouveaux médicaments choisis parmi les alpha -(1-R-3-azétidinyl)- alpha -phényl-acétamides et -acétonitriles alpha -substitués répondant à la formule :
FR7812434A 1977-04-27 1978-04-26 Azetidinyl-acetonitriles et -acetamides, compositions antiarythmiques contenant ces composes et utilisation de ces compositions Granted FR2388793A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/791,431 US4133881A (en) 1977-04-27 1977-04-27 Azetidinyl acetonitrile and acetamide antiarrhythmia compositions and methods

Publications (2)

Publication Number Publication Date
FR2388793A1 true FR2388793A1 (fr) 1978-11-24
FR2388793B1 FR2388793B1 (fr) 1982-11-26

Family

ID=25153706

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7812434A Granted FR2388793A1 (fr) 1977-04-27 1978-04-26 Azetidinyl-acetonitriles et -acetamides, compositions antiarythmiques contenant ces composes et utilisation de ces compositions

Country Status (6)

Country Link
US (1) US4133881A (fr)
JP (1) JPS53137950A (fr)
CA (1) CA1103674A (fr)
DE (1) DE2818672A1 (fr)
FR (1) FR2388793A1 (fr)
GB (1) GB1598846A (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2461699A1 (fr) * 1979-07-19 1981-02-06 Robins Co Inc A H Nouveaux derives de type methylene-3 azetidine utiles comme medicaments et compositions therapeutiques les contenant
FR2461703A1 (fr) * 1979-07-19 1981-02-06 Robins Co Inc A H Procede pour preparer des composes de type methylenecycloamines
FR2783246A1 (fr) * 1998-09-11 2000-03-17 Aventis Pharma Sa Derives d'azetidine, leur preparation et les medicaments les contenant
US6518264B2 (en) 1998-09-11 2003-02-11 Aventis Pharma S.A. Azetidine derivatives, their preparation and medicaments containing them

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4571393A (en) * 1982-08-19 1986-02-18 A. H. Robins Company, Incorporated 3-Phenoxy-1-azetidinecarboxamides
US5183902A (en) * 1985-02-28 1993-02-02 A. H. Robins Company, Incorporated Method of treating muscular tension, muscle spasticity and anxiety with 3-aryloxy and 3-arylthioazetidinecarboxamides
US6410746B1 (en) 1999-04-27 2002-06-25 Research Foundation Of State University Of New York, The Metal cataltsts and methods for making and using same
US7030051B2 (en) 2001-08-27 2006-04-18 The Research Foundation Of State University Of New York Dirhodium catalyst compositions and methods for using same
US6962891B2 (en) 2001-08-27 2005-11-08 The Research Foundation Of State University Of New York Solid support dirhodium catalyst compositions and methods for making and using same
DE10144872A1 (de) * 2001-09-12 2003-03-27 Bayer Cropscience Gmbh Azetidinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel
CN1802351A (zh) * 2003-06-11 2006-07-12 麦克公司 被取代的3-烷基和3-链烯基氮杂环丁烷衍生物
US7700798B1 (en) 2005-06-08 2010-04-20 The Research Foundation Of State University Of New York Erogorgiaene congeners and methods and intermediates useful in the preparation of same
US7816536B2 (en) * 2005-06-10 2010-10-19 The Research Foundation Of State University Of New York 4-substituted and 7-substituted indoles, benzofurans, benzothiophenes, benzimidazoles, benzoxazoles, and benzothiazoles and methods for making same
US7906652B2 (en) * 2005-11-28 2011-03-15 Merck Sharp & Dohme Corp. Heterocycle-substituted 3-alkyl azetidine derivatives
US7385064B1 (en) 2005-11-30 2008-06-10 The Research Foundation Of State University Of New York Catalysts for use in enantioselective synthesis
RU2011137454A (ru) * 2009-02-10 2013-03-20 Эбботт Лэборетриз Агонисты и антагонисты s1p5-рецепторов и способы их применения

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2642608A1 (de) * 1975-09-23 1977-03-31 Robins Co Inc A H 4-hydroxymethyl-2-pyrrolidinone und verfahren zu ihrer herstellung

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3318869A (en) * 1966-05-18 1967-05-09 Searle & Co Complex nitriles containing the azabicycloalkane structure
FR2289185A1 (fr) * 1974-10-30 1976-05-28 Scherico Ltd Composes azacycliques
US4002766A (en) * 1974-12-26 1977-01-11 A. H. Robins Company, Incorporated Antiarrhythmia methods

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2642608A1 (de) * 1975-09-23 1977-03-31 Robins Co Inc A H 4-hydroxymethyl-2-pyrrolidinone und verfahren zu ihrer herstellung

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2461699A1 (fr) * 1979-07-19 1981-02-06 Robins Co Inc A H Nouveaux derives de type methylene-3 azetidine utiles comme medicaments et compositions therapeutiques les contenant
FR2461703A1 (fr) * 1979-07-19 1981-02-06 Robins Co Inc A H Procede pour preparer des composes de type methylenecycloamines
FR2783246A1 (fr) * 1998-09-11 2000-03-17 Aventis Pharma Sa Derives d'azetidine, leur preparation et les medicaments les contenant
WO2000015609A1 (fr) * 1998-09-11 2000-03-23 Aventis Pharma S.A. Derives d'azetidine, leur preparation et les medicaments les contenant
US6518264B2 (en) 1998-09-11 2003-02-11 Aventis Pharma S.A. Azetidine derivatives, their preparation and medicaments containing them

Also Published As

Publication number Publication date
JPS626545B2 (fr) 1987-02-12
JPS53137950A (en) 1978-12-01
FR2388793B1 (fr) 1982-11-26
GB1598846A (en) 1981-09-23
CA1103674A (fr) 1981-06-23
US4133881A (en) 1979-01-09
DE2818672A1 (de) 1978-11-09

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Legal Events

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