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FR2378026A1 - Medicaments contenant des derives de sulfure d'hydroxymethyl-2 amino-2' diphenyle - Google Patents

Medicaments contenant des derives de sulfure d'hydroxymethyl-2 amino-2' diphenyle

Info

Publication number
FR2378026A1
FR2378026A1 FR7812694A FR7812694A FR2378026A1 FR 2378026 A1 FR2378026 A1 FR 2378026A1 FR 7812694 A FR7812694 A FR 7812694A FR 7812694 A FR7812694 A FR 7812694A FR 2378026 A1 FR2378026 A1 FR 2378026A1
Authority
FR
France
Prior art keywords
hydroxymethyl
amino
products containing
diphenyl sulfide
medicinal products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7812694A
Other languages
English (en)
Other versions
FR2378026B1 (fr
Inventor
Nariman Bomanshaw Mehta
Lawrence Edward Brieaddy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of FR2378026A1 publication Critical patent/FR2378026A1/fr
Application granted granted Critical
Publication of FR2378026B1 publication Critical patent/FR2378026B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Médicaments contenant, à titre d'ingrédients actifs, des composés répondant à la formule
FR7812694A 1975-07-21 1978-04-28 Medicaments contenant des derives de sulfure d'hydroxymethyl-2 amino-2' diphenyle Granted FR2378026A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/597,697 US3997540A (en) 1975-07-21 1975-07-21 O [(O-piperazinocarbonyl-phenyl)-thio]-benzoates

Publications (2)

Publication Number Publication Date
FR2378026A1 true FR2378026A1 (fr) 1978-08-18
FR2378026B1 FR2378026B1 (fr) 1980-10-31

Family

ID=24392586

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7621931A Granted FR2318622A1 (fr) 1975-07-21 1976-07-19 Derives de substitution du sulfure de diphenyle et medicament contenant ces substances
FR7812694A Granted FR2378026A1 (fr) 1975-07-21 1978-04-28 Medicaments contenant des derives de sulfure d'hydroxymethyl-2 amino-2' diphenyle

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR7621931A Granted FR2318622A1 (fr) 1975-07-21 1976-07-19 Derives de substitution du sulfure de diphenyle et medicament contenant ces substances

Country Status (28)

Country Link
US (6) US3997540A (fr)
JP (1) JPS5214737A (fr)
AT (1) AT356079B (fr)
AU (1) AU500698B2 (fr)
BE (1) BE844298A (fr)
CA (1) CA1081696A (fr)
CH (2) CH631700A5 (fr)
DE (1) DE2632400A1 (fr)
DK (1) DK325776A (fr)
ES (1) ES449939A1 (fr)
FI (1) FI64363C (fr)
FR (2) FR2318622A1 (fr)
GB (1) GB1561072A (fr)
HK (1) HK14483A (fr)
IE (1) IE43278B1 (fr)
IL (1) IL50062A (fr)
IT (1) IT1066007B (fr)
LU (1) LU75416A1 (fr)
MC (1) MC1113A1 (fr)
MY (1) MY8400101A (fr)
NL (1) NL7607975A (fr)
NZ (1) NZ181503A (fr)
PH (1) PH15375A (fr)
PT (1) PT65382B (fr)
SE (2) SE428296B (fr)
SG (1) SG4683G (fr)
SU (1) SU697050A3 (fr)
ZA (1) ZA764267B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4056632A (en) * 1975-07-21 1977-11-01 Burroughs Wellcome Co. 2-Hydroxymethyl-2'-aminomethyl-diphenylsulfides and method of use
DE2732750A1 (de) * 1977-07-20 1979-02-08 Merck Patent Gmbh Basische thioaether und verfahren zu ihrer herstellung
JPS55325A (en) * 1978-06-16 1980-01-05 Kyowa Hakko Kogyo Co Ltd Novel benzamide compound
FR2470780A1 (fr) * 1979-12-07 1981-06-12 Inst Francais Du Petrole Nouveaux oligomeres de thio-p-phenylene dicarboxy-telecheliques, leur preparation et leur utilisation dans le domaine des polycondensats segmentes
DE68903263T2 (de) * 1988-10-10 1993-05-19 Akzo Nv Substituierte aromatische verbindungen mit zentraler nervensystem-wirkung.
EP0396827A1 (fr) * 1989-05-09 1990-11-14 SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu Dérivés de 2-phénylthiobenzylamine et leurs sels d'addition des acides
GB8913011D0 (en) * 1989-06-06 1989-07-26 Wellcome Found Anticonvulsant pyrazines
GB8912971D0 (en) * 1989-06-06 1989-07-26 Wellcome Found Halogen substituted diphenylsulfides
CN1084742C (zh) * 1995-11-08 2002-05-15 史密丝克莱恩比彻姆公司 3－苯基－1－亚甲二氧基苯基－1,2－二氢化茚－2－羧酸衍生物的制备方法
WO2005012331A1 (fr) 2003-07-31 2005-02-10 Tranzyme Pharma Composes macrocycliques definis spatialement utiles pour la decouverte de medicaments
US8088733B2 (en) * 2006-07-06 2012-01-03 Tranzyme Pharma Inc. Methods of using macrocyclic agonists of the ghrelin receptor for treatment of gastrointestinal motility disorders

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2046512A1 (de) * 1969-09-22 1971-04-01 Merck & Co , Ine , Rahway, N J (V St A) Phenylthiobenzylamine

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1769423A (en) * 1927-05-27 1930-07-01 Chem Ind Basel Sulfides of aromatic compounds and process of making same
US2454260A (en) * 1946-02-12 1948-11-16 Hoffmann La Roche Preparation of metal mercaptides of amino-aryl mercaptans
US3514480A (en) * 1967-01-19 1970-05-26 Standard Oil Co Process for producing sulfur containing aromatic carboxylic acids
US3682968A (en) * 1969-06-25 1972-08-08 Merck & Co Inc Anti-inflammatory salicylic acid derivatives
US3884922A (en) * 1969-07-31 1975-05-20 Yoshitomi Pharmaceutical 11-(4-Pyridylalkyl-piperazino)-dibenzothiazepines
US3803143A (en) * 1969-09-08 1974-04-09 Eisai Co Ltd 6-amino alkylene 6,7-dihydro-5h-dibenzo (b,g),(1,5)thiazocines
US3674844A (en) * 1970-04-20 1972-07-04 Merck & Co Inc Salicylic acid derivatives
US3824243A (en) * 1970-10-23 1974-07-16 E Henderson Mono-o-phthalyl piperazine and mono-piperazine mono-phthalate di-salts
US3927093A (en) * 1972-10-10 1975-12-16 Squibb & Sons Inc 2-(O-aminophenylthio)benzyl alcohols

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2046512A1 (de) * 1969-09-22 1971-04-01 Merck & Co , Ine , Rahway, N J (V St A) Phenylthiobenzylamine

Also Published As

Publication number Publication date
SU697050A3 (ru) 1979-11-05
US4123555A (en) 1978-10-31
NZ181503A (en) 1978-07-28
FI64363C (fi) 1983-11-10
DE2632400C2 (fr) 1988-06-09
US4095027A (en) 1978-06-13
DK325776A (da) 1977-01-22
SE8007171L (sv) 1980-10-14
US4061863A (en) 1977-12-06
FR2318622A1 (fr) 1977-02-18
CH636603A5 (de) 1983-06-15
MC1113A1 (fr) 1977-05-18
ZA764267B (en) 1978-03-29
JPS5214737A (en) 1977-02-03
FI64363B (fi) 1983-07-29
LU75416A1 (fr) 1977-04-06
HK14483A (en) 1983-05-06
SE7608203L (sv) 1977-01-22
CA1081696A (fr) 1980-07-15
FR2318622B1 (fr) 1979-01-19
SG4683G (en) 1983-09-09
DE2632400A1 (de) 1977-02-24
SE428296B (sv) 1983-06-20
PT65382A (en) 1976-08-01
AU1602076A (en) 1978-01-26
ATA530976A (de) 1979-09-15
JPS6113468B2 (fr) 1986-04-14
US4091100A (en) 1978-05-23
FR2378026B1 (fr) 1980-10-31
IE43278L (en) 1977-01-21
PH15375A (en) 1982-12-10
AU500698B2 (en) 1979-05-31
GB1561072A (en) 1980-02-13
MY8400101A (en) 1984-12-31
ES449939A1 (es) 1977-07-01
US3997540A (en) 1976-12-14
IT1066007B (it) 1985-03-04
BE844298A (fr) 1977-01-19
FI762077A (fr) 1977-01-22
IL50062A0 (en) 1976-09-30
AT356079B (de) 1980-04-10
US4103020A (en) 1978-07-25
NL7607975A (nl) 1977-01-25
PT65382B (en) 1978-06-08
IL50062A (en) 1980-07-31
CH631700A5 (de) 1982-08-31
IE43278B1 (en) 1981-01-28

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