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FR2366297A1 - Nouvelles cephalosporines, leur procede de preparation et leur application en therapeutique - Google Patents

Nouvelles cephalosporines, leur procede de preparation et leur application en therapeutique

Info

Publication number
FR2366297A1
FR2366297A1 FR7729509A FR7729509A FR2366297A1 FR 2366297 A1 FR2366297 A1 FR 2366297A1 FR 7729509 A FR7729509 A FR 7729509A FR 7729509 A FR7729509 A FR 7729509A FR 2366297 A1 FR2366297 A1 FR 2366297A1
Authority
FR
France
Prior art keywords
therapeutics
preparation
application
new cephalosporins
cephalosporins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7729509A
Other languages
English (en)
Other versions
FR2366297B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoire Glaxo Wellcome SA
Glaxo Laboratories Ltd
Original Assignee
Laboratoires Glaxo SA
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Glaxo SA, Glaxo Laboratories Ltd filed Critical Laboratoires Glaxo SA
Publication of FR2366297A1 publication Critical patent/FR2366297A1/fr
Application granted granted Critical
Publication of FR2366297B1 publication Critical patent/FR2366297B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des céphalosporines. Les composés conformes à l'invention répondent à la formule suivante :
FR7729509A 1976-10-01 1977-09-30 Nouvelles cephalosporines, leur procede de preparation et leur application en therapeutique Granted FR2366297A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB40919/76A GB1591439A (en) 1976-10-01 1976-10-01 7-syn (oxyimino -acylamido) cephalosporins

Publications (2)

Publication Number Publication Date
FR2366297A1 true FR2366297A1 (fr) 1978-04-28
FR2366297B1 FR2366297B1 (fr) 1982-12-03

Family

ID=10417257

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7729509A Granted FR2366297A1 (fr) 1976-10-01 1977-09-30 Nouvelles cephalosporines, leur procede de preparation et leur application en therapeutique

Country Status (8)

Country Link
US (1) US4168309A (fr)
JP (1) JPS5353690A (fr)
BE (1) BE859257A (fr)
CH (1) CH633558A5 (fr)
DE (1) DE2744135A1 (fr)
FR (1) FR2366297A1 (fr)
GB (1) GB1591439A (fr)
NL (1) NL7710718A (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2522659A1 (fr) * 1982-03-04 1983-09-09 Bristol Myers Co Nouveaux derives de cephalosporine, leur procede de preparation et composition anti-bacterienne les contenant
EP0121244A2 (fr) * 1983-03-30 1984-10-10 Bristol-Myers Company Dérivés de céphalosporine
EP0162394A2 (fr) * 1984-05-22 1985-11-27 Bayer Ag Céphalosporines et procédé pour leur préparation

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4282219A (en) * 1979-08-01 1981-08-04 Merck & Co., Inc. 7-N-Heterocyclyl cephalosporins and antibiotic pharmaceutical compositions containing them
US4283397A (en) * 1979-08-01 1981-08-11 Merck & Co., Inc. 7-N-Heterocyclyl cephalosporins and antibiotic pharmaceutical compositions containing them
US4406899A (en) * 1982-03-04 1983-09-27 Bristol-Myers Company Cephalosporins
DE3207840A1 (de) * 1982-03-04 1983-09-15 Hoechst Ag, 6230 Frankfurt "cephalosporinderivate und verfahren zu ihrer herstellung"
US4536335A (en) * 1982-06-18 1985-08-20 Bristol-Myers Company Carbapenem antibiotics
US4486586A (en) * 1983-02-10 1984-12-04 Bristol-Myers Company Cephalosporin derivatives
GB8410000D0 (en) * 1984-04-17 1984-05-31 Fujisawa Pharmaceutical Co Cephem compounds
GB8424692D0 (en) * 1984-10-01 1984-11-07 Glaxo Group Ltd Chemical compounds
JPH06102668B2 (ja) * 1985-08-06 1994-12-14 萬有製薬株式会社 新規セフアロスポリン誘導体
JPH06104674B2 (ja) * 1984-11-12 1994-12-21 萬有製薬株式会社 新規セフアロスポリン誘導体
US4665066A (en) * 1984-12-24 1987-05-12 Eli Lilly And Company 3-thiazolomethyl cephalosporins as antibiotics
DE3587997D1 (de) * 1984-12-27 1995-04-06 Banyu Pharma Co Ltd Isoindolinderivate.
GR861118B (en) 1985-04-30 1986-08-18 Lilly Co Eli 7-substituted bicyclic pyrazolidinones
US4714760A (en) * 1985-08-20 1987-12-22 Bristol-Myers Company Cephalosporin intermediates
US4659812A (en) * 1985-08-20 1987-04-21 Bristol-Myers Company Cephalosporin intermediates
EP0227986B1 (fr) * 1985-12-09 1993-03-24 Banyu Pharmaceutical Co., Ltd. Dérivés de l'iso-indoline et procédé pour le préparation
US4814328A (en) * 1986-03-19 1989-03-21 Banyu Pharmaceutical Co., Ltd. Cephalosporin derivatives, and antibacterial agents
US5147871A (en) * 1986-07-03 1992-09-15 Hoffmann La-Roche, Inc. Anti-bacterial cephalosporin compounds
US4868294A (en) * 1986-07-11 1989-09-19 Bristol-Myers Company Process for preparing cephalosporin intermediates
CS273349B2 (en) * 1988-03-31 1991-03-12 Hoffmann La Roche Method of cephalosporin's new derivatives production
US5162523A (en) * 1989-07-21 1992-11-10 Hoffmann-La Roche Inc. Cephalosporin antibacterial compounds
US5159077A (en) * 1989-07-21 1992-10-27 Hoffmann-La Roche Inc. Penam antibacterial compounds
WO2006008749A1 (fr) * 2004-07-16 2006-01-26 Hetero Drugs Limited Procede de preparation d'intermediaires de cephalosporine pures

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU71550A1 (fr) 1973-12-21 1976-04-13
US4144393A (en) * 1973-12-21 1979-03-13 Glaxo Laboratories Limited 3-Acetoxymethyl cephalosporins having at position-7 a carboxy substituted α-etherified hydroxyiminoarylacetamido group
GB1555471A (en) * 1975-06-19 1979-11-14 Glaxo Lab Ltd 7 carbamoylalkoxyimino acetamido 3 em 4 carboxylic acidsand derivatives thereof

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2522659A1 (fr) * 1982-03-04 1983-09-09 Bristol Myers Co Nouveaux derives de cephalosporine, leur procede de preparation et composition anti-bacterienne les contenant
EP0121244A2 (fr) * 1983-03-30 1984-10-10 Bristol-Myers Company Dérivés de céphalosporine
EP0121244A3 (en) * 1983-03-30 1985-10-02 Bristol-Myers Company Cephalosporin derivatives
EP0162394A2 (fr) * 1984-05-22 1985-11-27 Bayer Ag Céphalosporines et procédé pour leur préparation
EP0162394A3 (en) * 1984-05-22 1986-12-30 Bayer Ag Cephalosporins and process for their preparation
US4686216A (en) * 1984-05-22 1987-08-11 Bayer Aktiengesellschaft 7-[2-(2-aminothiazol-4-yl)-2-oximino-acetamido-3-quaternary-ammonium-methyl-3-cephem-4-carboxylates

Also Published As

Publication number Publication date
US4168309A (en) 1979-09-18
CH633558A5 (de) 1982-12-15
FR2366297B1 (fr) 1982-12-03
DE2744135A1 (de) 1978-04-06
BE859257A (fr) 1978-03-30
JPS5353690A (en) 1978-05-16
NL7710718A (nl) 1978-04-04
GB1591439A (en) 1981-06-24

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Legal Events

Date Code Title Description
ST Notification of lapse