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FR2358891A1 - Composes heterocycliques contenant un azote, utilise comme agents analgesiques et anti-inflammatoires - Google Patents

Composes heterocycliques contenant un azote, utilise comme agents analgesiques et anti-inflammatoires

Info

Publication number
FR2358891A1
FR2358891A1 FR7721069A FR7721069A FR2358891A1 FR 2358891 A1 FR2358891 A1 FR 2358891A1 FR 7721069 A FR7721069 A FR 7721069A FR 7721069 A FR7721069 A FR 7721069A FR 2358891 A1 FR2358891 A1 FR 2358891A1
Authority
FR
France
Prior art keywords
analgesic
heterocyclic compounds
compounds containing
inflammatory agents
containing nitrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7721069A
Other languages
English (en)
Other versions
FR2358891B1 (fr
Inventor
Kazuo Kubo
Noriki Ito
Isao Souzu
Yasuo Isomura
Hiroshige Homma
Masuo Murakami
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP8748676A external-priority patent/JPS5321196A/ja
Priority claimed from JP15822876A external-priority patent/JPS5384990A/ja
Priority claimed from JP46477A external-priority patent/JPS5384991A/ja
Priority claimed from JP3638477A external-priority patent/JPS53121764A/ja
Priority claimed from JP4242377A external-priority patent/JPS53127490A/ja
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Publication of FR2358891A1 publication Critical patent/FR2358891A1/fr
Application granted granted Critical
Publication of FR2358891B1 publication Critical patent/FR2358891B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

La présente invention concerne des composés hétérocycliques contenant un azote. Ces composés sont représentés par la formule :
FR7721069A 1976-07-22 1977-07-08 Composes heterocycliques contenant un azote, utilise comme agents analgesiques et anti-inflammatoires Granted FR2358891A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP8748676A JPS5321196A (en) 1976-07-22 1976-07-22 Novel nitrogen-containing heterocyclic compounds and their preparation
JP15822876A JPS5384990A (en) 1976-12-29 1976-12-29 Novel nitrogen-containing heterocyclic compound and its preparation
JP46477A JPS5384991A (en) 1977-01-05 1977-01-05 Novel nitrogen-containing heterocyclic compound and its preparation
JP3638477A JPS53121764A (en) 1977-03-31 1977-03-31 Heterocyclic compounds and process for their preparation
JP4242377A JPS53127490A (en) 1977-04-13 1977-04-13 Novel nitrogen-containing heterocyclic compound

Publications (2)

Publication Number Publication Date
FR2358891A1 true FR2358891A1 (fr) 1978-02-17
FR2358891B1 FR2358891B1 (fr) 1980-02-08

Family

ID=27517959

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7721069A Granted FR2358891A1 (fr) 1976-07-22 1977-07-08 Composes heterocycliques contenant un azote, utilise comme agents analgesiques et anti-inflammatoires

Country Status (9)

Country Link
US (4) US4186200A (fr)
AU (1) AU2726077A (fr)
BE (1) BE857008A (fr)
CA (1) CA1067079A (fr)
DE (1) DE2731982A1 (fr)
DK (1) DK313477A (fr)
FR (1) FR2358891A1 (fr)
GB (1) GB1588166A (fr)
SE (1) SE7708403L (fr)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2358891A1 (fr) * 1976-07-22 1978-02-17 Yamanouchi Pharma Co Ltd Composes heterocycliques contenant un azote, utilise comme agents analgesiques et anti-inflammatoires
JPS58152809A (ja) * 1982-03-05 1983-09-10 Eisai Co Ltd 安定な発泡性「膣」坐剤
US4602013A (en) * 1984-02-08 1986-07-22 Ortho Pharmaceutical Corporation Substituted 2-amino-4(1H)pyridones, 7-pyrrolo[1,2-a]pyridinones, 2-quinolizinones, 7-thiazolo[3,2-a]pyridinones and 2-pyrido[1,2-a]azepinones as vasodilators and bronchodilators
WO1989005809A1 (fr) * 1987-12-23 1989-06-29 Schering Corporation Composes d'imidazoquinoline et de pyrimidoquinoline, naphtyridine et de pyridopyrazine
US5070086A (en) * 1987-12-23 1991-12-03 Schering Corporation Imidazo- and pyrimido-quinoline, naphthyridine and pyridopyrazine compounds
IT1233860B (it) * 1988-02-08 1992-04-21 Isf Spa Derivati del peridroazacicloalca (1,2-a) imidazolo ad attivita' nootropa
DE3926770A1 (de) * 1989-08-12 1991-02-14 Basf Ag (1,2,4)triazolo(1,5-a)pyridine
IE911472A1 (en) * 1990-05-02 1991-11-06 Abbott Lab Quinolizinone type compounds
US5508272A (en) * 1993-06-15 1996-04-16 Bristol-Myers Squibb Company Compounds containing a fused bicycle ring and processes therefor
US5616775A (en) * 1994-05-05 1997-04-01 Bristol-Myers Squibb Co. Process for preparing homocystein analogs useful as intermediates for compounds containing a fused bicyclic ring
US5587375A (en) * 1995-02-17 1996-12-24 Bristol-Myers Squibb Company Azepinone compounds useful in the inhibition of ACE and NEP
US5877313A (en) * 1995-05-17 1999-03-02 Bristol-Myers Squibb Benzo-fused azepinone and piperidinone compounds useful in the inhibition of ACE and NEP
US5650408A (en) * 1995-06-07 1997-07-22 Karanewsky; Donald S. Thiazolo benzazepine containing dual action inhibitors
US5635504A (en) * 1995-06-07 1997-06-03 Bristol-Myers Squibb Co. Diazepine containing dual action inhibitors
AU1555897A (en) * 1996-02-02 1997-08-22 Ihara Chemical Industry Co. Ltd. Pyridone derivatives and herbicides
DE69807322T2 (de) 1997-01-22 2003-04-17 Ciba Speciality Chemicals Holding Inc., Basel Fotoaktivierbare stickstoffhaltige basen, die auf alpha-aminoketonen basieren
US6153233A (en) * 1998-08-12 2000-11-28 General Mills, Inc. Food item and its fabricating methods
DE60206072T2 (de) * 2001-12-21 2006-07-13 Bayer Healthcare Ag Aroylpyridinone
SE0302486D0 (sv) * 2003-09-18 2003-09-18 Astrazeneca Ab Novel compounds
TW200808763A (en) * 2006-05-08 2008-02-16 Astrazeneca Ab Novel compounds I
TW200808771A (en) * 2006-05-08 2008-02-16 Astrazeneca Ab Novel compounds II
US7625895B2 (en) * 2007-04-12 2009-12-01 Hoffmann-Le Roche Inc. Diphenyl-dihydro-imidazopyridinones
CN101918391B (zh) * 2007-11-06 2013-06-05 阿斯利康(瑞典)有限公司 一些2-吡嗪酮衍生物和它们在制备嗜中性白细胞弹性蛋白酶抑制剂中的用途
CA2641977C (fr) * 2008-11-12 2012-01-31 Baffin Inc. Fabrication et methode de fabrication de chaussures
TW201036957A (en) * 2009-02-20 2010-10-16 Astrazeneca Ab Novel salt 628
MX2012003644A (es) * 2009-10-02 2012-04-30 Astrazeneca Ab Compuestos de 2-piridona empleados como inhibidores de la elastasa neutrofila.
WO2018119374A1 (fr) 2016-12-22 2018-06-28 Cadent Therapeutics Modulateurs des récepteurs nmda et utilisations de ceux-ci
FI3830092T3 (fi) 2018-08-03 2023-07-21 Novartis Ag Heteroaromaattiset NMDA-reseptorimodulaattorit ja niiden käytöt
CN111662282B (zh) * 2019-03-07 2021-07-06 湖南化工研究院有限公司 氮杂环并吡啶类化合物及其中间体
CN113480541B (zh) * 2019-03-07 2022-09-02 湖南化工研究院有限公司 咪唑并吡啶化合物及其中间体的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL126596C (fr) * 1964-02-11
CH433321A (de) * 1964-02-11 1967-04-15 Geigy Ag J R Verfahren zur Herstellung von neuen, kondensierten heterocyclischen Verbindungen
US3334095A (en) * 1965-02-16 1967-08-01 Sandoz Ag Novel pyrrolo-oxazines and pyrrolo-oxazoles
US3334091A (en) * 1965-03-25 1967-08-01 Sandoz Ag Sedatives
US3334099A (en) * 1965-03-31 1967-08-01 Sandoz Ag Novel pyrrolo-diazepines, pyrrolo-imidazolidines, and pyrrolo-pyrimidines
AT299212B (de) * 1966-11-02 1972-06-12 Chinoin Gyogyszer Es Vegyeszet Verfahren zur Herstellung von neuen Homopyrimidazol-Derivaten sowie von deren Salzen
SU562978A1 (ru) * 1975-12-02 1978-07-30 Филиал Всесоюзного Научно-Исследовательского Химико-Фармацевтического Института Имени С.Орджоникидзе Производные тиазолидина, обладающие противогрибковой активностью и способ их получени
FR2358891A1 (fr) * 1976-07-22 1978-02-17 Yamanouchi Pharma Co Ltd Composes heterocycliques contenant un azote, utilise comme agents analgesiques et anti-inflammatoires

Also Published As

Publication number Publication date
US4288438A (en) 1981-09-08
GB1588166A (en) 1981-04-15
BE857008A (fr) 1978-01-20
FR2358891B1 (fr) 1980-02-08
US4284778A (en) 1981-08-18
US4186200A (en) 1980-01-29
SE7708403L (sv) 1978-01-23
CA1067079A (fr) 1979-11-27
AU2726077A (en) 1979-01-25
DE2731982A1 (de) 1978-01-26
US4251533A (en) 1981-02-17
DK313477A (da) 1978-01-23

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