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FR2355830A1 - Nouveaux derives de 6-7-benzomorphane, leur obtention et composition pharmaceutique les contenant - Google Patents

Nouveaux derives de 6-7-benzomorphane, leur obtention et composition pharmaceutique les contenant

Info

Publication number
FR2355830A1
FR2355830A1 FR7718828A FR7718828A FR2355830A1 FR 2355830 A1 FR2355830 A1 FR 2355830A1 FR 7718828 A FR7718828 A FR 7718828A FR 7718828 A FR7718828 A FR 7718828A FR 2355830 A1 FR2355830 A1 FR 2355830A1
Authority
FR
France
Prior art keywords
benzomorphane
obtaining
pharmaceutical composition
composition containing
new derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7718828A
Other languages
English (en)
Other versions
FR2355830B1 (fr
Inventor
Antony Marie Akkerman
Hermanus Carolus Cathari Bakel
Henriette G Breevoort-Uurbanus
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ACF Chemiefarma NV
Original Assignee
ACF Chemiefarma NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ACF Chemiefarma NV filed Critical ACF Chemiefarma NV
Publication of FR2355830A1 publication Critical patent/FR2355830A1/fr
Application granted granted Critical
Publication of FR2355830B1 publication Critical patent/FR2355830B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

Nouveaux dérivés de 6,7-benzomorphane. Ils ont pour formule :
FR7718828A 1976-06-21 1977-06-20 Nouveaux derives de 6-7-benzomorphane, leur obtention et composition pharmaceutique les contenant Granted FR2355830A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB25577/76A GB1575009A (en) 1976-06-21 1976-06-21 6,7-benzomorphan derivatives

Publications (2)

Publication Number Publication Date
FR2355830A1 true FR2355830A1 (fr) 1978-01-20
FR2355830B1 FR2355830B1 (fr) 1981-04-30

Family

ID=10229936

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7718828A Granted FR2355830A1 (fr) 1976-06-21 1977-06-20 Nouveaux derives de 6-7-benzomorphane, leur obtention et composition pharmaceutique les contenant

Country Status (11)

Country Link
US (2) US4234591A (fr)
JP (1) JPS52156869A (fr)
BE (1) BE855938A (fr)
CH (1) CH634562A5 (fr)
DE (1) DE2726836A1 (fr)
DK (1) DK270077A (fr)
FR (1) FR2355830A1 (fr)
GB (1) GB1575009A (fr)
IE (1) IE44938B1 (fr)
LU (1) LU77585A1 (fr)
NL (1) NL7706328A (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2460298A1 (fr) * 1979-06-28 1981-01-23 Sterling Drug Inc Procede de preparation de 2,6-methano-3-benzazocines

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19907874A1 (de) * 1999-02-23 2000-08-24 Boehringer Ingelheim Pharma N-(5-Phenyl-tetrahydrofuranyl)methyl- und N-(6-Phenyl-tetrahydropyranyl)methyl substituierte 1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocin-10-ole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US7501433B2 (en) * 2002-05-17 2009-03-10 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
US7923454B2 (en) * 2002-05-17 2011-04-12 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
AU2003234621A1 (en) 2002-05-17 2003-12-02 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
US8017622B2 (en) * 2003-05-16 2011-09-13 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
US10138207B2 (en) 2012-11-09 2018-11-27 Purdue Pharma, L.P. Benzomorphan analogs and the use thereof
CA2900023A1 (fr) * 2013-01-31 2014-08-07 Purdue Pharma L.P. Analogues de benzomorphane et leur utilisation
CA2948144A1 (fr) * 2014-05-06 2015-11-12 Purdue Pharma L.P. Analogues du benzomorphane et leur utilisation

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2000041A1 (fr) * 1968-01-05 1969-08-29 Hoffmann La Roche
GB1185432A (en) * 1967-06-07 1970-03-25 Sumitomo Chemical Co Process for Producing Benzomorphane Derivatives

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE582575A (fr) * 1958-09-22
NL130089C (fr) * 1963-11-07
US3639407A (en) * 1965-05-05 1972-02-01 Geigy Chem Corp Novel 1 2 3 4 5 6-hexahydro-6-phenyl-2 6-methano-3-benzazocines
DE1545827C3 (de) * 1965-06-25 1975-09-11 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von 6,7-Benzomorphanen
US3499906A (en) * 1966-05-20 1970-03-10 Merck & Co Inc 5,9-diethyl-2'-hydroxy-2-substituted-6,7-benzomorphans
US3639410A (en) * 1968-07-26 1972-02-01 Sterling Drug Inc 1 2 3 4 5 6 - hexahydro - 8 - substituted-6-alkyl-11-(h or a lkyl) - 26-methano-3-benzazocines
US3511846A (en) * 1968-12-16 1970-05-12 Geigy Chem Corp Process for the preparation of optically active benzazocines
BR6914879D0 (pt) * 1969-01-23 1973-02-08 Merck & Co Inc Processos quimicos
CS166804B2 (fr) * 1971-02-08 1976-03-29 Boehringer Sohn Ingelheim
DE2217420C3 (de) * 1972-04-12 1981-03-12 C.H. Boehringer Sohn, 6507 Ingelheim N-Thienylmethyl-Heterocyclen, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zubereitungen
DE2229695A1 (de) * 1972-06-19 1974-01-31 Boehringer Sohn Ingelheim 2-(heteroaryl-methyl)-5,9 beta-dialkyl6,7-benzomorphane, deren saeureadditionssalze sowie verfahren zu deren herstellung
US4087532A (en) * 1974-03-09 1978-05-02 Boehringer Ingelheim Gmbh Analgesically useful 2-tetrahydrofurfuryl-5-lower alkyl-2-oxy-6,7-benzomorphans and salts thereof
US3932422A (en) * 1974-05-20 1976-01-13 Sterling Drug Inc. 8-Methylene-3-azabicyclo[3.3.1]non-6-en-4-ones
DE2437610A1 (de) * 1974-08-05 1976-02-26 Boehringer Sohn Ingelheim Neue 5,9-beta-disubstituierte 2-tetrahydrofurfuryl-6,7-benzomorphane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung
US4108857A (en) * 1975-08-18 1978-08-22 Sterling Drug Inc. Imidazolylmethyl methanobenzazocines
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1185432A (en) * 1967-06-07 1970-03-25 Sumitomo Chemical Co Process for Producing Benzomorphane Derivatives
FR2000041A1 (fr) * 1968-01-05 1969-08-29 Hoffmann La Roche

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2460298A1 (fr) * 1979-06-28 1981-01-23 Sterling Drug Inc Procede de preparation de 2,6-methano-3-benzazocines

Also Published As

Publication number Publication date
DK270077A (da) 1977-12-22
DE2726836A1 (de) 1977-12-29
FR2355830B1 (fr) 1981-04-30
IE44938B1 (en) 1982-05-19
GB1575009A (en) 1980-09-17
US4288444A (en) 1981-09-08
JPS52156869A (en) 1977-12-27
CH634562A5 (de) 1983-02-15
US4234591A (en) 1980-11-18
LU77585A1 (fr) 1977-09-29
NL7706328A (nl) 1977-12-23
BE855938A (nl) 1977-12-21
IE44938L (en) 1977-12-21

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