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FR2348925A1 - PHENYLPIPERAZINE DERIVATIVES - Google Patents

PHENYLPIPERAZINE DERIVATIVES

Info

Publication number
FR2348925A1
FR2348925A1 FR7711669A FR7711669A FR2348925A1 FR 2348925 A1 FR2348925 A1 FR 2348925A1 FR 7711669 A FR7711669 A FR 7711669A FR 7711669 A FR7711669 A FR 7711669A FR 2348925 A1 FR2348925 A1 FR 2348925A1
Authority
FR
France
Prior art keywords
phenylpiperazine derivatives
phenylpiperazine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7711669A
Other languages
French (fr)
Other versions
FR2348925B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lilly Industries Ltd
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of FR2348925A1 publication Critical patent/FR2348925A1/en
Application granted granted Critical
Publication of FR2348925B1 publication Critical patent/FR2348925B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/24Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40Radicals substituted by oxygen atoms
    • C07D307/42Singly bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/16Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Furan Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
FR7711669A 1976-04-23 1977-04-19 PHENYLPIPERAZINE DERIVATIVES Granted FR2348925A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB16526/76A GB1575904A (en) 1976-04-23 1976-04-23 Phenyl piperazines

Publications (2)

Publication Number Publication Date
FR2348925A1 true FR2348925A1 (en) 1977-11-18
FR2348925B1 FR2348925B1 (en) 1980-04-11

Family

ID=10078930

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7711669A Granted FR2348925A1 (en) 1976-04-23 1977-04-19 PHENYLPIPERAZINE DERIVATIVES

Country Status (34)

Country Link
JP (1) JPS52151183A (en)
AR (2) AR222003A1 (en)
AT (1) AT355579B (en)
AU (1) AU514822B2 (en)
BE (1) BE853899A (en)
BG (2) BG27746A3 (en)
CA (1) CA1087617A (en)
CH (2) CH633009A5 (en)
CS (1) CS196360B2 (en)
DD (1) DD129790A5 (en)
DE (1) DE2717415A1 (en)
DK (1) DK176177A (en)
ES (2) ES457988A1 (en)
FI (1) FI63937C (en)
FR (1) FR2348925A1 (en)
GB (1) GB1575904A (en)
GR (1) GR64084B (en)
HU (1) HU176820B (en)
IE (1) IE44730B1 (en)
IL (1) IL51787A (en)
LU (1) LU77170A1 (en)
MX (1) MX4596E (en)
NL (1) NL7704456A (en)
NO (1) NO146710C (en)
NZ (1) NZ183715A (en)
OA (1) OA05643A (en)
PH (1) PH14124A (en)
PL (1) PL117466B1 (en)
PT (1) PT66452B (en)
RO (1) RO72831A (en)
SE (1) SE7704536L (en)
SU (2) SU664564A3 (en)
YU (1) YU104477A (en)
ZA (1) ZA771849B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0078007A1 (en) * 1981-10-28 1983-05-04 BASF Aktiengesellschaft Metallised polyazo dyestuffs

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1601310A (en) * 1978-05-23 1981-10-28 Lilly Industries Ltd Aryl hydantoins
JPH07157477A (en) * 1993-12-02 1995-06-20 Asahi Kagaku Kogyo Kk Production of thiazole derivative
CA2184685A1 (en) * 1994-03-11 1995-09-14 Kiyoshi Iwaoka 5-ht3 receptor agonist, novel thiazole derivative and intermediate thereof
GB9517381D0 (en) * 1995-08-24 1995-10-25 Pharmacia Spa Aryl and heteroaryl piperazine derivatives
NZ570844A (en) * 2006-02-28 2011-11-25 Helicon Therapeutics Inc Therapeutic piperazines as PDE4 inhibitors
US8927546B2 (en) 2006-02-28 2015-01-06 Dart Neuroscience (Cayman) Ltd. Therapeutic piperazines

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0078007A1 (en) * 1981-10-28 1983-05-04 BASF Aktiengesellschaft Metallised polyazo dyestuffs

Also Published As

Publication number Publication date
DE2717415A1 (en) 1977-11-10
AR222003A1 (en) 1981-04-15
DD129790A5 (en) 1978-02-08
IE44730B1 (en) 1982-03-10
MX4596E (en) 1982-06-25
FI63937B (en) 1983-05-31
ES457988A1 (en) 1978-07-16
LU77170A1 (en) 1979-01-18
SU664564A3 (en) 1979-05-25
NO146710B (en) 1982-08-16
AU514822B2 (en) 1981-02-26
ZA771849B (en) 1978-11-29
BG27746A3 (en) 1979-12-12
PH14124A (en) 1981-02-26
NO771398L (en) 1977-10-25
BG28055A3 (en) 1980-02-25
AU2438677A (en) 1978-10-26
FI771287A (en) 1977-10-24
CA1087617A (en) 1980-10-14
IL51787A0 (en) 1977-05-31
ATA285177A (en) 1979-08-15
AT355579B (en) 1980-03-10
SU727146A3 (en) 1980-04-05
DK176177A (en) 1977-10-24
NO146710C (en) 1982-11-24
NL7704456A (en) 1977-10-25
PL197550A1 (en) 1979-05-21
OA05643A (en) 1981-04-30
CH625802A5 (en) 1981-10-15
BE853899A (en) 1977-10-24
FR2348925B1 (en) 1980-04-11
HU176820B (en) 1981-05-28
YU104477A (en) 1983-01-21
PT66452B (en) 1979-03-09
AR222635A1 (en) 1981-06-15
IE44730L (en) 1977-10-23
PL117466B1 (en) 1981-08-31
GR64084B (en) 1980-01-21
IL51787A (en) 1980-02-29
PT66452A (en) 1977-05-01
RO72831A (en) 1983-08-03
JPS52151183A (en) 1977-12-15
CH633009A5 (en) 1982-11-15
RO72831B (en) 1983-07-30
NZ183715A (en) 1980-04-28
ES467948A1 (en) 1978-11-01
CS196360B2 (en) 1980-03-31
GB1575904A (en) 1980-10-01
SE7704536L (en) 1977-10-24
FI63937C (en) 1983-09-12

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Legal Events

Date Code Title Description
ST Notification of lapse