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FR2194436A1 - 3-formyloxindoles prepn - useful as medicaments for treating fatty degener-ation - Google Patents

3-formyloxindoles prepn - useful as medicaments for treating fatty degener-ation

Info

Publication number
FR2194436A1
FR2194436A1 FR7327984A FR7327984A FR2194436A1 FR 2194436 A1 FR2194436 A1 FR 2194436A1 FR 7327984 A FR7327984 A FR 7327984A FR 7327984 A FR7327984 A FR 7327984A FR 2194436 A1 FR2194436 A1 FR 2194436A1
Authority
FR
France
Prior art keywords
formyloxindoles
degener
prepn
ation
medicaments
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7327984A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of FR2194436A1 publication Critical patent/FR2194436A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Cpds of formula (I): (where R is F, Cl or 1-4C alkoxy; R1 is H, F or Cl; provided that R1 is not = H when R is 4-Cl) are prepd. by (a) hydrolysing a cpd (II): (where (i) R2 is 1-4C alkoxy and R3 is H or 2-4C alkanoyl, or (ii) R2 is di(1-4C alkyl)amino and R3 is H or CHO); or (b) reacting a cpd (III): with HCOOR5 (where R5 is 1-4C alkyl) in the presence of a strong base.
FR7327984A 1972-07-31 1973-07-31 3-formyloxindoles prepn - useful as medicaments for treating fatty degener-ation Withdrawn FR2194436A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27679572A 1972-07-31 1972-07-31

Publications (1)

Publication Number Publication Date
FR2194436A1 true FR2194436A1 (en) 1974-03-01

Family

ID=23058099

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7327984A Withdrawn FR2194436A1 (en) 1972-07-31 1973-07-31 3-formyloxindoles prepn - useful as medicaments for treating fatty degener-ation

Country Status (8)

Country Link
JP (1) JPS4945065A (en)
AU (1) AU5874573A (en)
BE (1) BE802995A (en)
DD (1) DD109626A5 (en)
DE (1) DE2338668A1 (en)
ES (1) ES417396A1 (en)
FR (1) FR2194436A1 (en)
NL (1) NL7310394A (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS551020A (en) * 1978-06-20 1980-01-07 Sumitomo Bakelite Co Electric wire or cable
JPS56113385A (en) * 1980-02-08 1981-09-07 Mie Yushi Kako Kk Making heat resistant glare-proof coating film
JPS5757776A (en) * 1980-09-26 1982-04-07 Toagosei Chem Ind Co Ltd Water absorption inhibitor composition
JPS58111631A (en) * 1981-12-24 1983-07-02 ダイワ精工株式会社 External mounting of fishing reel
WO1995014750A1 (en) * 1993-11-22 1995-06-01 Daikin Industries, Ltd. Mold-release agent, cured coating film prepared therefrom, and method of molding with said agent
EP2886541A1 (en) * 2013-12-19 2015-06-24 Sanofi Oxindole derivatives, preparation thereof and therapeutic use in the treatment of AMPK-related diseases

Also Published As

Publication number Publication date
BE802995A (en) 1974-01-30
DE2338668A1 (en) 1974-02-21
ES417396A1 (en) 1976-02-16
DD109626A5 (en) 1974-11-12
AU5874573A (en) 1975-02-06
JPS4945065A (en) 1974-04-27
NL7310394A (en) 1974-02-04

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Legal Events

Date Code Title Description
ST Notification of lapse