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FR2157899A1 - 16-mono and di-lower alkyl prostaglandin compsns - - for treatment of peptic ulcers - Google Patents

16-mono and di-lower alkyl prostaglandin compsns - - for treatment of peptic ulcers

Info

Publication number
FR2157899A1
FR2157899A1 FR7237371A FR7237371A FR2157899A1 FR 2157899 A1 FR2157899 A1 FR 2157899A1 FR 7237371 A FR7237371 A FR 7237371A FR 7237371 A FR7237371 A FR 7237371A FR 2157899 A1 FR2157899 A1 FR 2157899A1
Authority
FR
France
Prior art keywords
compsns
mono
treatment
lower alkyl
peptic ulcers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7237371A
Other languages
French (fr)
Other versions
FR2157899B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of FR2157899A1 publication Critical patent/FR2157899A1/en
Application granted granted Critical
Publication of FR2157899B1 publication Critical patent/FR2157899B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Pharmaceutical dosage units contain as active component an optically active or racemic form of the 16-methyl-, 16-ethyl-, 16,16-dimethyl-, 16,16-diethyl-, 16-ethyl-16-methyl-derivs. of PGE, PGE2, PGA, and PGA2, or their salts or their esters with carboxylic acids (1-8C alkyl) formulated to have an anti-secretory or antiulcer activity, the unit dose being adjusted to give a dosage rate of 0.7-5.7 mu g/Kg.
FR7237371A 1971-10-22 1972-10-20 16-mono and di-lower alkyl prostaglandin compsns - - for treatment of peptic ulcers Granted FR2157899A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19189971A 1971-10-22 1971-10-22
US23098872A 1972-03-01 1972-03-01

Publications (2)

Publication Number Publication Date
FR2157899A1 true FR2157899A1 (en) 1973-06-08
FR2157899B1 FR2157899B1 (en) 1976-08-20

Family

ID=26887514

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7237371A Granted FR2157899A1 (en) 1971-10-22 1972-10-20 16-mono and di-lower alkyl prostaglandin compsns - - for treatment of peptic ulcers

Country Status (1)

Country Link
FR (1) FR2157899A1 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2305972A1 (en) * 1975-04-04 1976-10-29 Schering Ag LYOPHILIZED POWDERS CONTAINING PROSTAGLANDINS
EP0001124A1 (en) * 1977-09-12 1979-03-21 THERA Gesellschaft für Patentverwertung mbH Drug mixtures for improving the utilisation of glucose in the cells and to reduce the bloodsugar level
EP0016610A2 (en) * 1979-03-19 1980-10-01 American Cyanamid Company Method for preserving an E-type prostaglandin and stabilized PGE-type in triethyl citrate solution

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2305972A1 (en) * 1975-04-04 1976-10-29 Schering Ag LYOPHILIZED POWDERS CONTAINING PROSTAGLANDINS
EP0001124A1 (en) * 1977-09-12 1979-03-21 THERA Gesellschaft für Patentverwertung mbH Drug mixtures for improving the utilisation of glucose in the cells and to reduce the bloodsugar level
EP0016610A2 (en) * 1979-03-19 1980-10-01 American Cyanamid Company Method for preserving an E-type prostaglandin and stabilized PGE-type in triethyl citrate solution
EP0016610A3 (en) * 1979-03-19 1981-08-05 American Cyanamid Company Method for preserving an e-type prostaglandin and stabilized pge-type in triethyl citrate solution

Also Published As

Publication number Publication date
FR2157899B1 (en) 1976-08-20

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Legal Events

Date Code Title Description
ST Notification of lapse