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FR2046114A5 - Benzimidazole derivs anthelmintic, antifung - al bactericidal, aericidal, insecticidal, nema - Google Patents

Benzimidazole derivs anthelmintic, antifung - al bactericidal, aericidal, insecticidal, nema

Info

Publication number
FR2046114A5
FR2046114A5 FR7003249A FR7003249A FR2046114A5 FR 2046114 A5 FR2046114 A5 FR 2046114A5 FR 7003249 A FR7003249 A FR 7003249A FR 7003249 A FR7003249 A FR 7003249A FR 2046114 A5 FR2046114 A5 FR 2046114A5
Authority
FR
France
Prior art keywords
alkyl
cycloalkyl
opt
phenyl
halo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7003249A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dynachim SARL
Original Assignee
Dynachim SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dynachim SARL filed Critical Dynachim SARL
Priority to FR7003249A priority Critical patent/FR2046114A5/en
Application granted granted Critical
Publication of FR2046114A5 publication Critical patent/FR2046114A5/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical
    • C07D235/32—Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Benzimidazole derivs; anthelmintic, antifungal, bactericidal, acaricidal, insecticidal, nematocidal. Cpds. of formula (I): (where R is 1-4 substituents chosen from halo, alkyl, aryl, alkoxy, alkylthio, CN, NO2; R1 is H, alkyl, alkenyl, aryl, aralkyl, trihalomethylthio, ethylthio or vinylthio in which at least 2 of the H atoms are replaced by halogen, -CZ-Y-R4 (III) A1 is alkyl, alkenyl, aralkyl, aralkenyl, cycloalkyl, cycloalkyl-alkyl, aryl, heteroaryl, heteroaralkyl (these gps. are opt. substd. by halo, alkoxy, NO2, CN) dialkylamino or nitrogen heterocyclic joined by the N atom (the heterocyclic opt. contains an oxygen or a second nitrogen, and has an alkyl and/or cycloalkyl residue contg. 1-12 atoms of C; A2 is H or lower alkyl or A1 and A2 together are opt. unsatd. divalent hydrocarbyl, a heterocarbon gp. contg. an S, O or N atom. these groups opt. contain an alkyl and/or cycloalkyl gp. contg. 1-12C atoms; Y and Z are O or S; R4 is alkyl, alkenyl, aralkyl, aralkenyl, phenyl, naphthyl, cycloalkyl, cycloalkylalkyl, furyl, thienyl, pyridyl, thiazolyl, oxazolyl, isothiazolyl, isoxazolyl, thiadiazolyl (all opt. substd. by halo, alkyl, phenyl, alkoxy, alkylthio, cyano, nitro or dialkylamino); R2 is H, alkyl, aryl (e.g. phenyl, naphthyl), heteroaryl, these gps. opt. substd. by halo, alkyl, phenyl, alkoxy, alkylthio, cyano, nitro; R3 is alkyl, alkenyl, aralkyl, aralkenyl, cycloalkyl, cycloalkyl-alkyl, phenyl, naphthyl, furyl, thienyl, pyridyl, thiazolyl, oxazolyl, isothiazolyl, isoxazolyl or thiadiazolyl (all opt. substd. by one or more halo, alkyl, phenyl, alkoxy, alkylthio, CN, NO2, dialkylamino) or an N-contg. heterocyclic joined via the N-atom (the heterocyclic may contain an oxygen or a second nitrogen atom and has an alkyl and/or cycloalkyl residue contg. 1-12 C atoms); when R2 = H or unsatd. alkyl, R3 must be a heteroaryl as above or one of the other gps. which carries a substituent nitrogen except when R1 is a Group II in which A1 is a residue carrying an N-substituent or A1 and A2 together form a divalent heterocarbon gp.).
FR7003249A 1970-01-30 1970-01-30 Benzimidazole derivs anthelmintic, antifung - al bactericidal, aericidal, insecticidal, nema Expired FR2046114A5 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7003249A FR2046114A5 (en) 1970-01-30 1970-01-30 Benzimidazole derivs anthelmintic, antifung - al bactericidal, aericidal, insecticidal, nema

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7003249A FR2046114A5 (en) 1970-01-30 1970-01-30 Benzimidazole derivs anthelmintic, antifung - al bactericidal, aericidal, insecticidal, nema

Publications (1)

Publication Number Publication Date
FR2046114A5 true FR2046114A5 (en) 1971-03-05

Family

ID=9049826

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7003249A Expired FR2046114A5 (en) 1970-01-30 1970-01-30 Benzimidazole derivs anthelmintic, antifung - al bactericidal, aericidal, insecticidal, nema

Country Status (1)

Country Link
FR (1) FR2046114A5 (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3978075A (en) * 1974-05-02 1976-08-31 Chinoin Gyogyszer-Es Vegyeszeti Termekek Gyara Rt Substituted carbamoyl benzimidazole derivatives with antifungal properties
WO1993010101A1 (en) * 1991-11-12 1993-05-27 Pfizer Limited Benzimidazole anthelmintic agents
US6653335B2 (en) 1995-04-12 2003-11-25 University Of Arizona Foundationa Pharmaceutical composition for inhibiting the growth of viruses and cancers
US6720349B2 (en) * 2000-09-26 2004-04-13 Uaf Technologies And Research, Llc Compounds for use in the treatment of cancer or viral infections
US6906091B2 (en) 1999-08-13 2005-06-14 Uaf Technologies And Research, Llc Method of cancer treatment
US6916836B2 (en) 2000-09-26 2005-07-12 Uaf Technologies And Research, Llc Compounds and methods for use thereof in the treatment of viral infections
US6930121B2 (en) 2000-09-26 2005-08-16 Uaf Technologies And Research, Llc Compounds and methods for use thereof in the treatment of viral infections
US6984654B2 (en) 1997-05-16 2006-01-10 Uaf Technologies And Research, Llc Cancer treatments and pharmaceutical compositions therefor
WO2016063293A1 (en) * 2014-10-21 2016-04-28 Oat & Iil India Laboratories Private Limited Novel 2-substituted imidazole compound and use thereof

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3978075A (en) * 1974-05-02 1976-08-31 Chinoin Gyogyszer-Es Vegyeszeti Termekek Gyara Rt Substituted carbamoyl benzimidazole derivatives with antifungal properties
WO1993010101A1 (en) * 1991-11-12 1993-05-27 Pfizer Limited Benzimidazole anthelmintic agents
US5475005A (en) * 1991-11-12 1995-12-12 Pfizer Inc. Benzimidazole anthelmintic agents
US6653335B2 (en) 1995-04-12 2003-11-25 University Of Arizona Foundationa Pharmaceutical composition for inhibiting the growth of viruses and cancers
US6984654B2 (en) 1997-05-16 2006-01-10 Uaf Technologies And Research, Llc Cancer treatments and pharmaceutical compositions therefor
US6906091B2 (en) 1999-08-13 2005-06-14 Uaf Technologies And Research, Llc Method of cancer treatment
US6720349B2 (en) * 2000-09-26 2004-04-13 Uaf Technologies And Research, Llc Compounds for use in the treatment of cancer or viral infections
US6916836B2 (en) 2000-09-26 2005-07-12 Uaf Technologies And Research, Llc Compounds and methods for use thereof in the treatment of viral infections
US6930121B2 (en) 2000-09-26 2005-08-16 Uaf Technologies And Research, Llc Compounds and methods for use thereof in the treatment of viral infections
WO2016063293A1 (en) * 2014-10-21 2016-04-28 Oat & Iil India Laboratories Private Limited Novel 2-substituted imidazole compound and use thereof

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Legal Events

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