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FR07C0073I2 - PAPILLOMAVIRUS VACCINE - Google Patents

PAPILLOMAVIRUS VACCINE

Info

Publication number
FR07C0073I2
FR07C0073I2 FR07C0073C FR07C0073C FR07C0073I2 FR 07C0073 I2 FR07C0073 I2 FR 07C0073I2 FR 07C0073 C FR07C0073 C FR 07C0073C FR 07C0073 C FR07C0073 C FR 07C0073C FR 07C0073 I2 FR07C0073 I2 FR 07C0073I2
Authority
FR
France
Prior art keywords
antibodies
useful
papillomavirus vaccine
mimics
diagnosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR07C0073C
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Georgetown University
Original Assignee
Georgetown University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25416951&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR07C0073(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Georgetown University filed Critical Georgetown University
Publication of FR07C0073I1 publication Critical patent/FR07C0073I1/fr
Application granted granted Critical
Publication of FR07C0073I2 publication Critical patent/FR07C0073I2/en
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

A recombinantly produced L1 major capsid protein which mimics conformational neutralizing epitopes on human and animal papilloma virions is provided. The recombinant proteins are useful as vaccines protective against papillomavirus infection. Antibodies to the recombinant protein are also provided. Such antibodies are useful in the diagnosis and treatment of viral infection.
FR07C0073C 1992-06-25 2007-12-21 PAPILLOMAVIRUS VACCINE Active FR07C0073I2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90310992A 1992-06-25 1992-06-25
PCT/US1993/006109 WO1994000152A1 (en) 1992-06-25 1993-06-24 Papillomavirus vaccines

Publications (2)

Publication Number Publication Date
FR07C0073I1 FR07C0073I1 (en) 2008-01-02
FR07C0073I2 true FR07C0073I2 (en) 2012-08-03

Family

ID=25416951

Family Applications (1)

Application Number Title Priority Date Filing Date
FR07C0073C Active FR07C0073I2 (en) 1992-06-25 2007-12-21 PAPILLOMAVIRUS VACCINE

Country Status (12)

Country Link
US (2) US20020068326A1 (en)
EP (2) EP0647140B1 (en)
AT (1) ATE380871T1 (en)
AU (1) AU697743C (en)
DE (9) DE122007000096I1 (en)
DK (1) DK0647140T3 (en)
ES (1) ES2294778T3 (en)
FR (1) FR07C0073I2 (en)
LU (8) LU91395I2 (en)
NL (8) NL300317I1 (en)
PT (1) PT647140E (en)
WO (1) WO1994000152A1 (en)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2113712C (en) 1991-07-19 2007-06-12 Ian Frazer Papilloma virus vaccine
US5437951A (en) * 1992-09-03 1995-08-01 The United States Of America As Represented By The Department Of Health And Human Services Self-assembling recombinant papillomavirus capsid proteins
US6153201A (en) * 1993-03-09 2000-11-28 University Of Rochester Oral immunization with papillomavirus virus-like particles
US8062642B1 (en) 1993-03-09 2011-11-22 University Of Rochester Production of papillomavirus capsid protein and virus-like particles
DE4415743C2 (en) * 1994-05-04 1996-10-10 Deutsches Krebsforsch Papillomaviruses, means for their detection and for the therapy of diseases caused by them
US5888516A (en) * 1994-05-16 1999-03-30 Merck & Co. Inc. Recombinant papillomavirus vaccines
RO117541B1 (en) * 1994-05-16 2002-04-30 Merck & Co Inc Process for preparing a human papillomavirus vaccine for the administration to humans
AUPM566794A0 (en) * 1994-05-17 1994-06-09 University Of Queensland, The Process and product
AU683564B2 (en) * 1994-05-17 1997-11-13 University Of Queensland, The Recombinant papilloma virus L1
NZ293461A (en) * 1994-09-22 1998-04-27 Merck & Co Inc Dna encoding human papillomavirus type 6a, compounds derived therefrom
JPH11504801A (en) 1994-10-07 1999-05-11 ラッツ ギッスマン Papillomavirus-like particles, fusion proteins and methods for their production
US5840306A (en) * 1995-03-22 1998-11-24 Merck & Co., Inc. DNA encoding human papillomavirus type 18
IL117459A (en) * 1995-03-22 2005-11-20 Merck & Co Inc Dna encoding human papillomavirus type 18
US5820870A (en) * 1995-03-22 1998-10-13 Merck & Co., Inc. Recombinant human papillomavirus type 18 vaccine
US6908615B1 (en) 1996-03-18 2005-06-21 Merck & Co., Inc. DNA encoding human papilloma virus type 18
GB9621091D0 (en) 1996-10-09 1996-11-27 Fondation Pour Le Perfectionem Attenuated microorganisms strains and their uses
CA2295316C (en) * 1997-07-03 2007-06-26 University Of Colorado, University Technology Corporation Homogeneous human papilloma virus capsomere containing compositions, methods for manufacture, and the use thereof as diagnostic, prophylactic or therapy
US6228368B1 (en) 1997-10-06 2001-05-08 Loyola University Of Chicago Papilloma virus capsomere formulations and method of use
CA2229955C (en) 1998-02-20 2003-12-09 Medigene Gmbh Papilloma virus capsomere vaccine formulations and methods of use
US7182947B2 (en) 1998-02-20 2007-02-27 Medigene Ag Papillomavirus truncated L1 protein and fusion protein constructs
US7494658B2 (en) 1998-02-20 2009-02-24 Medigene Ag Papilloma virus truncated L1 protein and fusion protein constructs
US20020039584A1 (en) 1998-02-20 2002-04-04 Medigene Ag Papilloma virus capsomere vaccine formulations and methods of use
US6926897B1 (en) 1998-03-24 2005-08-09 Medigene Aktiengesellschaft Medicament for the avoidance or treatment of papillomavirus-specific tumour
WO2000002924A1 (en) * 1998-07-13 2000-01-20 Loyola University Of Chicago Papillomavirus cellular receptor
US6692752B1 (en) 1999-09-08 2004-02-17 Smithkline Beecham Biologicals S.A. Methods of treating human females susceptible to HSV infection
WO2000023105A2 (en) * 1998-10-16 2000-04-27 Smithkline Beecham Biologicals S.A. Adjuvant systems and vaccines
GB0109297D0 (en) 2001-04-12 2001-05-30 Glaxosmithkline Biolog Sa Vaccine
WO2003103570A2 (en) 2001-08-01 2003-12-18 University Of Rochester Transcutaneous immunization against papillomavirus with papillomavirus virus-like particles
GB0206360D0 (en) 2002-03-18 2002-05-01 Glaxosmithkline Biolog Sa Viral antigens
DK1944318T3 (en) 2003-07-21 2011-06-14 Transgene Sa Multifunctional cytokines
TWI457133B (en) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa Novel composition
ES2675915T3 (en) 2006-09-26 2018-07-13 Infectious Disease Research Institute Vaccine composition containing a synthetic adjuvant
US20090181078A1 (en) 2006-09-26 2009-07-16 Infectious Disease Research Institute Vaccine composition containing synthetic adjuvant
CA2896131C (en) 2007-03-02 2020-04-07 Glaxosmithkline Biologicals S.A. Novel method and compositions
CN102099053A (en) 2008-05-26 2011-06-15 卡迪拉保健有限公司 Combined measles-human papilloma vaccine
GB0815872D0 (en) 2008-09-01 2008-10-08 Pasteur Institut Novel method and compositions
GB0820822D0 (en) 2008-11-13 2008-12-24 Inst Catala D Oncologia Novel product and processes
US20120115207A1 (en) * 2009-04-03 2012-05-10 Deutsches Krebsforschungszentrum Enhanced production of papillomavirus-like particles with a modified baculovirus expression system
HUE031051T2 (en) 2009-06-05 2017-06-28 Infectious Disease Res Inst Synthetic glucopyranosyl lipid adjuvants and vaccine compositions containing them
WO2011026111A1 (en) 2009-08-31 2011-03-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Oral delivery of a vaccine to the large intestine to induce mucosal immunity
CA2795403C (en) 2010-04-08 2019-01-15 University Of Pittsburgh-Of The Commonwealth System Of Higher Education B-cell antigen presenting cell assay
JP6054942B2 (en) 2011-04-08 2016-12-27 イミューン デザイン コーポレイション Immunogenic compositions and methods of using the compositions to elicit humoral and cellular immune responses
EP2811981B1 (en) 2012-02-07 2019-05-08 Infectious Disease Research Institute Improved adjuvant formulations comprising tlr4 agonists and methods of using the same
US9555099B2 (en) 2012-05-16 2017-01-31 Immune Design Corp. Vaccines for HSV-2
JP6430949B2 (en) 2012-10-23 2018-11-28 エモリー ユニバーシティ Conjugates, compositions, and related methods of GM-CSF and IL-4
EP3711768A1 (en) 2013-04-18 2020-09-23 Immune Design Corp. Gla monotherapy for use in cancer treatment
US9463198B2 (en) 2013-06-04 2016-10-11 Infectious Disease Research Institute Compositions and methods for reducing or preventing metastasis
EP3915579A1 (en) 2013-12-31 2021-12-01 Infectious Disease Research Institute Single vial vaccine formulations
CN108885212B (en) 2016-02-22 2022-05-31 勃林格殷格翰维特梅迪卡有限公司 Method for immobilizing biomolecules
WO2017200852A1 (en) 2016-05-16 2017-11-23 Infectious Disease Research Institute Formulation containing tlr agonist and methods of use
WO2017200957A1 (en) 2016-05-16 2017-11-23 Infectious Disease Research Institute Pegylated liposomes and methods of use
WO2017210364A1 (en) 2016-06-01 2017-12-07 Infectious Disease Research Institute Nanoalum particles containing a sizing agent
KR20240096685A (en) 2017-06-15 2024-06-26 액세스 투 어드밴스드 헬스 인스티튜트 Nanostructured lipid carriers and stable emulsions and uses thereof
JP7339942B2 (en) 2017-09-08 2023-09-06 アクセス ツー アドバンスト ヘルス インスティチュート Liposomal formulation containing saponin and method of use
JP2022532944A (en) 2019-05-25 2022-07-20 アクセス ツー アドバンスト ヘルス インスティチュート Compositions and Methods for Spray Drying of adjuvant Vaccine Emulsions
US20230310323A1 (en) 2020-09-04 2023-10-05 Access To Advanced Health Institute Co-lyophilized rna and nanostructured lipid carrier
WO2024052882A1 (en) 2022-09-09 2024-03-14 Access To Advanced Health Institute Immunogenic vaccine composition incorporating a saponin

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57106626A (en) * 1980-12-22 1982-07-02 Teijin Ltd Cytotoxic protein complex and its preparation
US4455296A (en) * 1982-02-02 1984-06-19 Board Of Regents, The University Of Texas System Hybrid cell lines producing monoclonal antibodies directed against Haemophilus influenzae
US4671958A (en) * 1982-03-09 1987-06-09 Cytogen Corporation Antibody conjugates for the delivery of compounds to target sites
FR2524487B1 (en) * 1982-04-05 1985-11-22 Pasteur Institut DNA FRAGMENTS ENCODING POLYPEPTIDES CONTAINING AT LEAST ONE ANTIGENIC DETERMINANT OF PAPILLOMAVIRUS, IN PARTICULAR OF THE HPV 1A TYPE AND CORRESPONDING POLYPEPTIDES
US4596674A (en) * 1984-09-11 1986-06-24 Merck & Co., Inc. Immunogenic HAV peptides
DE3625257A1 (en) * 1986-07-23 1988-02-04 Behringwerke Ag EXPRESSION PRODUCTS OF THE HUMAN PAPILLOMVIRUS TYPE 16 AND 18, FOR THESE PROTEINS, SPECIFIC ANTIBODIES AND THESE ANTIBODIES OR. CORRESPONDING DNA-CONTAINING DIAGNOSTICS
NZ223009A (en) * 1986-12-31 1990-06-26 Nl Rivm Of Thoven Oligosaccharides containing d-ribose d-ribitol and phosphate units mimicing haemophilus influenzae type b antigens
EP0320942A3 (en) * 1987-12-18 1989-10-04 American Cyanamid Company Novel polysaccharides novel macromolecular conjugates of the polysaccharides
CA2038581A1 (en) * 1990-03-20 1991-09-21 Martin Muller Seroreactive epitopes of human papillomavirus (hpv) 16 proteins
CA2113712C (en) 1991-07-19 2007-06-12 Ian Frazer Papilloma virus vaccine

Also Published As

Publication number Publication date
DE122007000099I1 (en) 2008-03-27
LU91398I2 (en) 2008-02-14
US20020068326A1 (en) 2002-06-06
DE122007000101I1 (en) 2008-03-27
EP0647140B1 (en) 2007-12-12
DE69334192D1 (en) 2008-01-24
LU91399I2 (en) 2008-02-14
EP0647140A4 (en) 1997-03-19
NL300315I1 (en) 2008-02-01
WO1994000152A1 (en) 1994-01-06
DE122007000097I1 (en) 2008-03-27
AU1135295A (en) 1996-02-08
EP0647140A1 (en) 1995-04-12
DK0647140T3 (en) 2008-02-04
LU91397I2 (en) 2008-02-14
DE122007000100I1 (en) 2008-03-27
LU91400I2 (en) 2008-02-14
LU91396I2 (en) 2008-02-14
NL300319I1 (en) 2008-03-03
LU91393I2 (en) 2008-02-14
EP1835029A1 (en) 2007-09-19
DE122007000096I1 (en) 2008-03-27
NL300315I2 (en) 2008-03-03
NL300322I1 (en) 2008-03-03
AU697743B2 (en) 1998-10-15
NL300316I1 (en) 2008-02-01
US8012679B1 (en) 2011-09-06
NL300321I1 (en) 2008-03-03
ES2294778T3 (en) 2008-04-01
ATE380871T1 (en) 2007-12-15
FR07C0073I1 (en) 2008-01-02
NL300317I1 (en) 2008-02-01
NL300318I1 (en) 2008-02-01
DE122007000094I1 (en) 2008-03-27
DE69334192T2 (en) 2008-12-04
LU91395I2 (en) 2008-02-14
DE122007000098I1 (en) 2008-03-27
NL300318I2 (en) 2008-03-03
DE122007000095I1 (en) 2008-03-27
NL300320I1 (en) 2008-03-03
PT647140E (en) 2007-12-27
LU91394I2 (en) 2008-02-14
AU697743C (en) 2007-06-14

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