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FI980862A0 - Kirala metylfenyloxazolidinoner - Google Patents

Kirala metylfenyloxazolidinoner

Info

Publication number
FI980862A0
FI980862A0 FI980862A FI980862A FI980862A0 FI 980862 A0 FI980862 A0 FI 980862A0 FI 980862 A FI980862 A FI 980862A FI 980862 A FI980862 A FI 980862A FI 980862 A0 FI980862 A0 FI 980862A0
Authority
FI
Finland
Prior art keywords
methylphenyloxazolidinones
kirala
production
relates
pharmaceutical agents
Prior art date
Application number
FI980862A
Other languages
English (en)
Finnish (fi)
Other versions
FI980862A (sv
Inventor
Henry Laurent
Eckhard Ottow
Gerald Kirsch
Helmut Wachtel
Herbert Schneider
Daryl Faulds
Harald Dinter
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of FI980862A0 publication Critical patent/FI980862A0/sv
Publication of FI980862A publication Critical patent/FI980862A/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
FI980862A 1995-10-20 1998-04-17 Kirala metylfenyloxazolidinoner FI980862A (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19540475A DE19540475A1 (de) 1995-10-20 1995-10-20 Chirale Methylphenyloxazolidinone
PCT/DE1996/000259 WO1997015561A1 (de) 1995-10-20 1996-02-09 Chirale methylphenyloxazolidinone

Publications (2)

Publication Number Publication Date
FI980862A0 true FI980862A0 (sv) 1998-04-17
FI980862A FI980862A (sv) 1998-04-17

Family

ID=7776217

Family Applications (1)

Application Number Title Priority Date Filing Date
FI980862A FI980862A (sv) 1995-10-20 1998-04-17 Kirala metylfenyloxazolidinoner

Country Status (25)

Country Link
US (1) US6025376A (sv)
EP (1) EP0859766B1 (sv)
JP (1) JPH11513693A (sv)
KR (1) KR100417359B1 (sv)
CN (1) CN1077103C (sv)
AT (1) ATE201203T1 (sv)
AU (1) AU715344B2 (sv)
CZ (1) CZ292167B6 (sv)
DE (2) DE19540475A1 (sv)
DK (1) DK0859766T3 (sv)
ES (1) ES2158284T3 (sv)
FI (1) FI980862A (sv)
GR (1) GR3036305T3 (sv)
HK (1) HK1015788A1 (sv)
HU (1) HUP9802630A3 (sv)
IL (1) IL117091A (sv)
NO (1) NO310772B1 (sv)
NZ (1) NZ301645A (sv)
PL (1) PL185526B1 (sv)
PT (1) PT859766E (sv)
RU (1) RU2156243C2 (sv)
SK (1) SK282653B6 (sv)
TR (1) TR199800679T2 (sv)
WO (1) WO1997015561A1 (sv)
ZA (1) ZA961074B (sv)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1007038A2 (en) * 1997-08-21 2000-06-14 Takeda Chemical Industries, Ltd. Anti-inflammatory agent
DE19928312A1 (de) * 1999-06-16 2000-12-21 Schering Ag Arzneimittelzubereitung mit verzögerter Wirkstoffabgabe
US6808902B1 (en) 1999-11-12 2004-10-26 Amgen Inc. Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
EP1216700A1 (de) * 2000-12-21 2002-06-26 Schering Aktiengesellschaft Transdermalsysteme (TDS) enthaltend (R)-(-)-Methylphenyloxazolidinon-Derivate, Inhibitoren der Phosphodiesterase IV
GB0111872D0 (en) * 2001-05-15 2001-07-04 Northwick Park Inst For Medica Therapeutic agents and methods
DE60235989D1 (de) 2001-06-26 2010-05-27 Amgen Fremont Inc Antikörper gegen opgl
EP1414517A4 (en) * 2001-06-26 2008-02-06 Photomed Technologies Inc MULTIPLE WAVELENGTH ILLUMINATOR
US20080026984A1 (en) * 2002-02-04 2008-01-31 Alfama - Investigacao E Desenvolvimento De Productos Farmaceuticos Lda Methods for treating inflammatory disease by administering aldehydes and derivatives thereof
NZ534912A (en) * 2002-02-04 2007-08-31 Alfama Investigacao E Desenvol supramolecule aggregate comprising CO containing organometallic or transition metal complex and anti-inflammatory agent or biphosphonate phosphonate derivative
US6962940B2 (en) 2002-03-20 2005-11-08 Celgene Corporation (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione: methods of using and compositions thereof
ES2211344B1 (es) * 2002-12-26 2005-10-01 Almirall Prodesfarma, S.A. Nuevos derivados de piridazin-3(2h)-ona.
CA2511823A1 (en) * 2002-12-30 2004-07-22 Amgen Inc. Combination therapy with co-stimulatory factors
WO2004098592A1 (ja) * 2003-05-06 2004-11-18 Senju Pharmaceutical Co. Ltd. オキサゾリジノン誘導体含有組成物
ES2251866B1 (es) 2004-06-18 2007-06-16 Laboratorios Almirall S.A. Nuevos derivados de piridazin-3(2h)-ona.
ES2251867B1 (es) * 2004-06-21 2007-06-16 Laboratorios Almirall S.A. Nuevos derivados de piridazin-3(2h)-ona.
WO2006115509A2 (en) 2004-06-24 2006-11-02 Novartis Vaccines And Diagnostics Inc. Small molecule immunopotentiators and assays for their detection
WO2007073226A1 (en) * 2005-12-20 2007-06-28 Alfama - Investigação E Desenvolvimento De Produtos Farmacêuticos Lda Method for treating a mammal by administration of a compound having the ability to release co
GB0601394D0 (en) 2006-01-24 2006-03-01 Hemocorm Ltd Therapeutic delivery of carbon monoxide
ES2320954B1 (es) * 2007-03-02 2010-03-16 Laboratorio Almirall S.A. Nuevo procedimiento de preparacion de 3-metil-4-fenilisoxazolo (3,4-d)iridazin-7(6h)-ona.
US9163044B2 (en) 2011-04-19 2015-10-20 Alfama, Inc. Carbon monoxide releasing molecules and uses thereof
EP2734235B1 (en) 2011-07-21 2017-03-22 Alfama, Inc. Ruthenium carbon monoxide releasing molecules and uses thereof
EP3402777B1 (en) 2015-12-16 2023-12-13 Merck Sharp & Dohme Corp. Oxazolidinones as taro inhibitors
US10736905B1 (en) 2016-09-09 2020-08-11 Shahin Fatholahi Nefopam dosage forms and methods of treatment
US10736874B1 (en) 2017-09-08 2020-08-11 Shahin Fatholahi Methods for treating pain associated with sickle cell disease
US11446311B2 (en) 2017-09-08 2022-09-20 Shahin Fatholahi Methods for treating pain associated with sickle cell disease
WO2019193091A1 (en) * 2018-04-05 2019-10-10 Universiteit Hasselt Selective pde4d inhibitors against demyelinating diseases

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2413935A1 (de) * 1974-03-20 1975-10-16 Schering Ag 4-(polyalkoxy-phenyl)-2-pyrrolidone
DE2541855A1 (de) * 1975-09-18 1977-03-31 Schering Ag 4-(polyalkoxy-phenyl)-2-pyrrolidone ii
FR2358155A1 (fr) * 1976-07-15 1978-02-10 Lapinet Eugene Composition pour le traitement et la prevention de l'irritation et de l'inflammation de la peau, de l'oeil et des muqueuses
DE2655369A1 (de) * 1976-12-03 1978-06-08 Schering Ag 5-(subst. phenyl)-oxazolidinone und deren schwefelanaloga sowie verfahren zu deren herstellung
DE3438839A1 (de) * 1984-10-19 1986-04-24 Schering AG, 1000 Berlin und 4709 Bergkamen Pharmazeutische praeparate
US5783591A (en) * 1984-10-19 1998-07-21 Schering Aktiengesellschaft Administration of oxazolidinone and pyrolidinone compounds for the treatment of inflammation
DE3639225A1 (de) * 1986-11-14 1988-05-19 Schering Ag Verwendung von 5-(subst. phenyl)-oxazolidinonderiaten als psychopharmaka
WO1991000092A1 (en) * 1989-06-13 1991-01-10 Smithkline Beecham Corporation Inhibition of interleukin-1 and tumor necrosis factor production by monocytes and/or macrophages
JPH06500078A (ja) * 1990-08-03 1994-01-06 スミスクライン・ビーチャム・コーポレイション Ｔｎｆ抑制剤
PT100441A (pt) * 1991-05-02 1993-09-30 Smithkline Beecham Corp Pirrolidinonas, seu processo de preparacao, composicoes farmaceuticas que as contem e uso
US5227369A (en) * 1991-07-11 1993-07-13 The Regents Of The University Of California Compositions and methods for inhibiting leukocyte adhesion to cns myelin
EP0628628A4 (en) * 1992-02-24 1995-11-15 Q P Corp GLA OGENE BACTERIA, CULTURE OF THE SAME BACTERIA, GLA OGENE SUBSTANCE CONTAINING THE SAME AND USE OF THE SAME.
GB9204808D0 (en) * 1992-03-04 1992-04-15 Rhone Poulenc Rorer Ltd Novel compositions of matter
US5264437A (en) * 1992-03-20 1993-11-23 Syntex (U.S.A.) Inc. Optionally substituted pyrido[2,3-d]pyridine-2,4(1H,3H)-diones and pyrido[2,]pyrimidine-2(1H,3H)-ones
US5672622A (en) * 1994-04-21 1997-09-30 Berlex Laboratories, Inc. Treatment of multiple sclerosis

Also Published As

Publication number Publication date
NO981688D0 (no) 1998-04-15
SK49598A3 (en) 1998-09-09
TR199800679T2 (xx) 1998-07-21
ES2158284T3 (es) 2001-09-01
HUP9802630A2 (hu) 1999-04-28
WO1997015561A1 (de) 1997-05-01
EP0859766B1 (de) 2001-05-16
SK282653B6 (sk) 2002-11-06
IL117091A (en) 2000-07-26
JPH11513693A (ja) 1999-11-24
IL117091A0 (en) 1996-06-18
RU2156243C2 (ru) 2000-09-20
ATE201203T1 (de) 2001-06-15
NO981688L (no) 1998-04-15
NZ301645A (en) 1999-11-29
HUP9802630A3 (en) 2000-01-28
FI980862A (sv) 1998-04-17
DK0859766T3 (da) 2001-08-13
CN1200115A (zh) 1998-11-25
EP0859766A1 (de) 1998-08-26
AU715344B2 (en) 2000-01-20
NO310772B1 (no) 2001-08-27
PL326322A1 (en) 1998-09-14
PL185526B1 (pl) 2003-05-30
US6025376A (en) 2000-02-15
CZ120198A3 (cs) 1998-07-15
PT859766E (pt) 2001-10-30
CZ292167B6 (cs) 2003-08-13
KR19990064339A (ko) 1999-07-26
GR3036305T3 (en) 2001-10-31
AU4712396A (en) 1997-05-15
HK1015788A1 (en) 1999-10-22
ZA961074B (en) 1997-02-26
DE59606920D1 (de) 2001-06-21
KR100417359B1 (ko) 2004-03-19
DE19540475A1 (de) 1997-04-24
CN1077103C (zh) 2002-01-02

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