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FI972641A - Kalkonit ja niiden esterit, joilla on antiproliferatiivinen vaikutus kohtu-, munasarja- ja rintakasvaimiin - Google Patents

Kalkonit ja niiden esterit, joilla on antiproliferatiivinen vaikutus kohtu-, munasarja- ja rintakasvaimiin Download PDF

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Publication number
FI972641A
FI972641A FI972641A FI972641A FI972641A FI 972641 A FI972641 A FI 972641A FI 972641 A FI972641 A FI 972641A FI 972641 A FI972641 A FI 972641A FI 972641 A FI972641 A FI 972641A
Authority
FI
Finland
Prior art keywords
pct
chalcones
esters
date jun
breast tumors
Prior art date
Application number
FI972641A
Other languages
English (en)
Swedish (sv)
Other versions
FI972641A0 (fi
Inventor
Ezio Bombardelli
Salvatore Mancuso
Monache Franco Delle
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Publication of FI972641A0 publication Critical patent/FI972641A0/fi
Publication of FI972641A publication Critical patent/FI972641A/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/017—Esters of hydroxy compounds having the esterified hydroxy group bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
FI972641A 1994-12-20 1997-06-19 Kalkonit ja niiden esterit, joilla on antiproliferatiivinen vaikutus kohtu-, munasarja- ja rintakasvaimiin FI972641A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI942568A IT1271301B (it) 1994-12-20 1994-12-20 Calconi naturali e sintetici e loro esteri ad attivita' antiproliferativa nei tumori dell'utero,dell'ovaio e del seno e formulazioni che li contengono
PCT/EP1995/004770 WO1996019209A1 (en) 1994-12-20 1995-12-04 Chalcones and esters thereof with antiproliferative activity in uterus, ovary and breast tumours

Publications (2)

Publication Number Publication Date
FI972641A0 FI972641A0 (fi) 1997-06-19
FI972641A true FI972641A (fi) 1997-08-14

Family

ID=11370023

Family Applications (1)

Application Number Title Priority Date Filing Date
FI972641A FI972641A (fi) 1994-12-20 1997-06-19 Kalkonit ja niiden esterit, joilla on antiproliferatiivinen vaikutus kohtu-, munasarja- ja rintakasvaimiin

Country Status (22)

Country Link
US (1) US5808137A (fi)
EP (1) EP0800387B1 (fi)
JP (1) JP2004131509A (fi)
KR (1) KR100264369B1 (fi)
CN (1) CN1087609C (fi)
AT (1) ATE222756T1 (fi)
AU (1) AU689357B2 (fi)
CA (1) CA2208351C (fi)
CZ (1) CZ288043B6 (fi)
DE (1) DE69527980T2 (fi)
DK (1) DK0800387T3 (fi)
ES (1) ES2181806T3 (fi)
FI (1) FI972641A (fi)
HU (1) HU225501B1 (fi)
IT (1) IT1271301B (fi)
NO (1) NO307926B1 (fi)
PL (1) PL183772B1 (fi)
PT (1) PT800387E (fi)
RU (1) RU2181284C2 (fi)
SI (1) SI9520139B (fi)
SK (1) SK282259B6 (fi)
WO (1) WO1996019209A1 (fi)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9712966D0 (en) * 1997-06-19 1997-08-27 Indena Spa Novel chalcones
US6423740B1 (en) 1997-06-19 2002-07-23 Indena S.P.A. Chalcones having antiproliferative activity
US6239114B1 (en) * 1997-09-26 2001-05-29 Kgk Synergize Compositions and methods for treatment of neoplastic diseases with combinations of limonoids, flavonoids and tocotrienols
GB9920908D0 (en) * 1999-09-03 1999-11-10 Indena Spa Chalcone coumarins
GB9920910D0 (en) 1999-09-03 1999-11-10 Indena Spa Novel chalcones
CN1447804A (zh) 2000-06-20 2003-10-08 阿特罗吉尼克斯公司 1,3－二－(被取代的苯基)－2－丙烯－1－酮及其治疗vcam－1介导的疾病的用途
CA2428753C (en) 2000-11-17 2013-05-21 Idenix (Cayman) Limited Methods for inhibiting the transmission of hiv using topically applied substituted 6-benzyl-4-oxopyrimidines
US7094801B2 (en) * 2001-12-19 2006-08-22 Atherogenics, Inc. Chalcone derivatives and their use to treat diseases
US7514579B2 (en) 2002-06-13 2009-04-07 Johns Hopkins University Boronic chalcone derivatives and uses thereof
AU2003303239A1 (en) * 2002-12-19 2004-07-14 Atherogenics, Inc. Process of making chalcone derivatives
KR20060121273A (ko) 2003-12-05 2006-11-28 다카라 바이오 가부시키가이샤 치료제
US20060063828A1 (en) * 2004-06-28 2006-03-23 Weingarten M D 1,2-Bis-(substituted-phenyl)-2-propen-1-ones and pharmaceutical compositions thereof
CN100336797C (zh) * 2005-08-19 2007-09-12 浙江大学 四取代查耳酮衍生物及制备方法和用途
GB0609386D0 (en) * 2006-05-11 2006-06-21 Active Botan Ltd Treating drug resistant cancers
US9132117B2 (en) 2013-06-17 2015-09-15 Kgk Synergize, Inc Compositions and methods for glycemic control of subjects with impaired fasting glucose
ES2540457B2 (es) * 2013-06-19 2015-12-28 Universidad De Sevilla Procedimiento de obtención de extractos de hojas de Corema album y su aplicación terapéutica
KR101731159B1 (ko) 2015-02-04 2017-04-28 계명대학교 산학협력단 2',4'-디하이드록시칼콘 화합물을 유효성분으로 포함하는 항진균용 조성물
CZ307046B6 (cs) * 2015-09-02 2017-12-13 Univerzita PalackĂ©ho v Olomouci Komplexy mědi s deriváty (E)-1-(2´-hydroxyfenyl)-3-fenylprop-2-en-1-onu a jejich použití jako léčiv v protinádorové terapii
CN111138264B (zh) * 2019-11-29 2023-08-04 温州医科大学 一种丁香醛衍生物及其在制备抗妇科肿瘤药物中的应用
CN113564103B (zh) * 2021-05-17 2023-01-06 南京医科大学 4,4’-二甲氧基查耳酮在延缓卵母细胞体内外老化中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH593224A5 (fi) * 1973-10-30 1977-11-30 Taisho Pharmaceutical Co Ltd
US5234951A (en) * 1986-12-12 1993-08-10 Tsumura Juntendo, Inc. Anti-ulcer agent comprising chalcone derivative
WO1988004288A1 (en) * 1986-12-12 1988-06-16 Tsumura Juntendo, Inc. Anti-ulcerous agent containing chalcone derivative as effective ingredient and novel chalcone derivatives
JPH05509078A (ja) * 1990-05-17 1993-12-16 ベイラー カレッジ オブ メディシン 成長抑制因とガンおよび細胞増殖性疾患措置法
AU2393992A (en) * 1991-07-24 1993-02-23 Baylor College Of Medicine Combination therapy using bioflavonoid compounds with anti-cancer drugs

Also Published As

Publication number Publication date
WO1996019209A1 (en) 1996-06-27
ITMI942568A1 (it) 1996-06-20
HUT77438A (hu) 1998-04-28
DE69527980D1 (de) 2002-10-02
CZ186997A3 (en) 1997-11-12
AU4301996A (en) 1996-07-10
CN1087609C (zh) 2002-07-17
SK78197A3 (en) 1997-12-10
IT1271301B (it) 1997-05-27
PT800387E (pt) 2002-12-31
KR100264369B1 (ko) 2000-08-16
CZ288043B6 (cs) 2001-04-11
HU225501B1 (en) 2007-01-29
NO307926B1 (no) 2000-06-19
ATE222756T1 (de) 2002-09-15
DE69527980T2 (de) 2003-05-28
CA2208351C (en) 2002-06-25
US5808137A (en) 1998-09-15
JP2004131509A (ja) 2004-04-30
NO972842L (no) 1997-06-19
PL183772B1 (pl) 2002-07-31
RU2181284C2 (ru) 2002-04-20
NO972842D0 (no) 1997-06-19
ES2181806T3 (es) 2003-03-01
FI972641A0 (fi) 1997-06-19
SK282259B6 (sk) 2001-12-03
CN1170362A (zh) 1998-01-14
EP0800387B1 (en) 2002-08-28
SI9520139A (en) 1997-10-31
ITMI942568A0 (it) 1994-12-20
CA2208351A1 (en) 1996-06-27
DK0800387T3 (da) 2002-12-23
AU689357B2 (en) 1998-03-26
EP0800387A1 (en) 1997-10-15
PL320787A1 (en) 1997-10-27
SI9520139B (sl) 1999-02-28

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