FI960165A - Säädetty apoptoosi - Google Patents

Säädetty apoptoosi Download PDF

Info

Publication number: FI960165A
Authority: FI; Finland
Prior art keywords: regulated apoptosis; apoptosis; regulated
Prior art date: 1993-07-16

Application number

FI960165A

Other languages

English (en)

Finnish (fi)

Swedish (sv)

Other versions

FI960165A0 (fi

Inventor

Gerald R Crabtree

Stuart L Schreiber

David M Spencer

Thomas J Wandless

Peter Belshaw

Original Assignee

Univ Leland Stanford Junior

Harvard College

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-07-16

Filing date

1996-01-15

Publication date

1996-01-26

1994-02-14 Priority claimed from PCT/US1994/001617 external-priority patent/WO1994018317A1/en

1996-01-15 Application filed by Univ Leland Stanford Junior, Harvard College filed Critical Univ Leland Stanford Junior

1996-01-15 Publication of FI960165A0 publication Critical patent/FI960165A0/fi

1996-01-26 Publication of FI960165A publication Critical patent/FI960165A/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/035—Fusion polypeptide containing a localisation/targetting motif containing a signal for targeting to the external surface of a cell, e.g. to the outer membrane of Gram negative bacteria, GPI- anchored eukaryote proteins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/09—Fusion polypeptide containing a localisation/targetting motif containing a nuclear localisation signal
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
- C07K2319/42—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a HA(hemagglutinin)-tag
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
- C07K2319/43—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a FLAG-tag
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/71—Fusion polypeptide containing domain for protein-protein interaction containing domain for transcriptional activaation, e.g. VP16
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/71—Fusion polypeptide containing domain for protein-protein interaction containing domain for transcriptional activaation, e.g. VP16
- C07K2319/715—Fusion polypeptide containing domain for protein-protein interaction containing domain for transcriptional activaation, e.g. VP16 containing a domain for ligand dependent transcriptional activation, e.g. containing a steroid receptor domain
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/80—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor
- C07K2319/81—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor containing a Zn-finger domain for DNA binding
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/90—Fusion polypeptide containing a motif for post-translational modification

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Genetics & Genomics (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Biomedical Technology (AREA)
General Health & Medical Sciences (AREA)
Gastroenterology & Hepatology (AREA)
Medicinal Chemistry (AREA)
Biotechnology (AREA)
Wood Science & Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
General Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cell Biology (AREA)
Toxicology (AREA)
Plant Pathology (AREA)
Physics & Mathematics (AREA)
Microbiology (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Plant Substances (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

FI960165A 1993-07-16 1996-01-15 Säädetty apoptoosi FI960165A (fi)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US9349993A	1993-07-16	1993-07-16
US17914394A	1994-01-07	1994-01-07
PCT/US1994/001617 WO1994018317A1 (en)	1993-02-12	1994-02-14	Regulated transcription of targeted genes and other biological events
PCT/US1994/008008 WO1995002684A1 (en)	1993-07-16	1994-07-18	Regulated apoptosis

Publications (2)

Publication Number	Publication Date
FI960165A0 FI960165A0 (fi)	1996-01-15
FI960165A true FI960165A (fi)	1996-01-26

Family

ID=27377531

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI960165A FI960165A (fi)	1993-07-16	1996-01-15	Säädetty apoptoosi

Country Status (6)

Country	Link
JP (1)	JPH09503645A (ja)
AU (1)	AU696991B2 (ja)
CA (1)	CA2167282A1 (ja)
FI (1)	FI960165A (ja)
HU (1)	HUT73100A (ja)
WO (1)	WO1995002684A1 (ja)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP4470226B2 (ja) *	1994-08-18	2010-06-02	アリアド・ファーマシューティカルズ・インコーポレイテッド	新規な多量体化剤
EP0785992A4 (en) *	1994-10-25	1999-12-22	Univ Leland Stanford Junior	TRANSFORMATION OF THE STATE OF CELLS PRODUCED BY GENETIC ENGINEERING
WO1998039418A1 (en) *	1997-03-07	1998-09-11	Ariad Gene Therapeutics, Inc.	New applications of gene therapy technology
CA2219080A1 (en) *	1995-06-07	1996-12-27	Ariad Gene Therapeutics, Inc.	Rapamycin-based regulation of biological events
US6187757B1 (en)	1995-06-07	2001-02-13	Ariad Pharmaceuticals, Inc.	Regulation of biological events using novel compounds
DE69715621T2 (de) *	1996-04-26	2003-05-22	Massachusetts Institute Of Technology, Cambridge	Drei hybriden screening test
JPH10234372A (ja) *	1997-02-27	1998-09-08	Boehringer Mannheim Corp	キメラ受容体を有する細胞とその作成方法、並びにその利用
US6271244B1 (en)	1998-06-03	2001-08-07	Gpi Nil Holdings, Inc.	N-linked urea or carbamate of heterocyclic thioester hair growth compositions and uses
US6187796B1 (en)	1998-06-03	2001-02-13	Gpi Nil Holdings, Inc.	Sulfone hair growth compositions and uses
US6187784B1 (en)	1998-06-03	2001-02-13	Gpi Nil Holdings, Inc.	Pipecolic acid derivative hair growth compositions and uses
US6274602B1 (en)	1998-06-03	2001-08-14	Gpi Nil Holdings, Inc.	Heterocyclic thioester and ketone hair growth compositions and uses
US5945441A (en) *	1997-06-04	1999-08-31	Gpi Nil Holdings, Inc.	Pyrrolidine carboxylate hair revitalizing agents
US6855543B1 (en)	1997-06-27	2005-02-15	Ono Pharmaceutical Co., Ltd.	Plasmid DNA containing reporter gene DNA and use of the same
US6982082B1 (en)	1997-08-27	2006-01-03	President And Fellows Of Harvard College	Gene therapy by cell specific targeting
US6153383A (en)	1997-12-09	2000-11-28	Verdine; Gregory L.	Synthetic transcriptional modulators and uses thereof
FR2774289B1 (fr) *	1998-02-03	2002-05-24	Goemar Lab Sa	Medicament pour le traitement des dereglements de l'apoptose
US6984635B1 (en)	1998-02-13	2006-01-10	Board Of Trustees Of The Leland Stanford Jr. University	Dimerizing agents, their production and use
AU3454799A (en) *	1998-03-30	1999-10-18	Baylor College Of Medicine	Regulated apoptosis using chemically induced dimerization of apoptosis factors
ATE473759T1 (de)	1998-05-22	2010-07-15	Univ Leland Stanford Junior	Bifunktionelle moleküle sowie darauf basierende therapien.
AU770459B2 (en)	1998-06-03	2004-02-19	Gpi Nil Holdings, Inc.	Heterocyclic ester and amide hair growth compositions and uses
US6172087B1 (en)	1998-06-03	2001-01-09	Gpi Nil Holding, Inc.	N-oxide of heterocyclic ester, amide, thioester, or ketone hair growth compositions and uses
JP4704565B2 (ja) *	1998-09-23	2011-06-15	ザイモジェネティクス，インコーポレイテッド	サイトカインレセプターｚａｌｐｈａ１１
GB9914650D0 (en) *	1999-06-24	1999-08-25	Angyogene Pharmaceuticals Ltd	Chimeric proteins mediating targeted apoptosis
GB9915074D0 (en) *	1999-06-28	1999-08-25	Cortecs Plc	Ligand-binding composition
US7498025B1 (en)	1999-11-19	2009-03-03	The Board Of Trustees Of The Leland Stanford Junior University	Targeted bifunctional molecules and therapies based thereon
US6887842B1 (en)	1999-11-19	2005-05-03	The Board Of Trustees Of The Leland Stanford Junior University	Modulating a pharmacokinetic property of a drug by administering a bifunctional molecule containing the drug
US7220552B1 (en)	1999-11-19	2007-05-22	The Board Of Trustees Of The Leland Stanford Junior University	Bifunctional molecules and their use in the disruption of protein-protein interactions
JP4963142B2 (ja)	2000-12-14	2012-06-27	学校法人慶應義塾	遺伝子型と表現型の対応付け分子とその構成要素、および対応付け分子の製造方法と利用方法
JP4547911B2 (ja)	2002-02-01	2010-09-22	アリアド・ファーマシューティカルズ・インコーポレイテッド	リン含有化合物およびその用途
US7638331B2 (en)	2004-01-02	2009-12-29	The Administration of the Tulane Rducation Fund	Directed apoptosis in COX-2 overexpressing cancer cells through expression targeted gene delivery
US7968762B2 (en)	2004-07-13	2011-06-28	Van Andel Research Institute	Immune-compromised transgenic mice expressing human hepatocyte growth factor (hHGF)
NZ597557A (en)	2006-03-02	2013-10-25	Uab Research Foundation	Mycobacterial disease detection, treatment, and drug discovery
EP2258858A1 (en)	2009-06-05	2010-12-08	Universitätsklinikum Freiburg	Transgenic LSD1 animal model for cancer
US10634668B2 (en)	2012-09-13	2020-04-28	Takara Bio Usa, Inc.	Modifiable chemical inducers of proximity and methods of using the same
EP3663405B8 (en)	2013-06-11	2024-10-30	Takara Bio USA, Inc.	Protein enriched microvesicles and methods of making and using the same
US11446398B2 (en)	2016-04-11	2022-09-20	Obsidian Therapeutics, Inc.	Regulated biocircuit systems
US10828330B2 (en)	2017-02-22	2020-11-10	IO Bioscience, Inc.	Nucleic acid constructs comprising gene editing multi-sites and uses thereof
JP7577340B2 (ja) *	2019-10-24	2024-11-05	国立大学法人千葉大学	細胞内脂質代謝酵素活性定量測定法、細胞内脂質代謝酵素活性定量測定用キット及び脂質代謝酵素活性制御剤のスクリーニング方法
CN116179608B (zh) *	2023-01-05	2024-03-01	昆明理工大学	一种dsRNA在免疫缺陷中华蜜蜂模型构建中的应用

1994
- 1994-07-18 JP JP7504752A patent/JPH09503645A/ja active Pending
- 1994-07-18 HU HU9600083A patent/HUT73100A/hu unknown
- 1994-07-18 AU AU73363/94A patent/AU696991B2/en not_active Expired
- 1994-07-18 CA CA002167282A patent/CA2167282A1/en not_active Abandoned
- 1994-07-18 WO PCT/US1994/008008 patent/WO1995002684A1/en not_active Application Discontinuation
1996
- 1996-01-15 FI FI960165A patent/FI960165A/fi unknown

Also Published As

Publication number	Publication date
WO1995002684A1 (en)	1995-01-26
AU696991B2 (en)	1998-09-24
FI960165A0 (fi)	1996-01-15
HUT73100A (en)	1996-06-28
AU7336394A (en)	1995-02-13
HU9600083D0 (en)	1996-03-28
JPH09503645A (ja)	1997-04-15
CA2167282A1 (en)	1995-01-26

Publication	Publication Date	Title
FI960165A (fi)	1996-01-26	Säädetty apoptoosi
FI940154A (fi)	1994-07-16	Substituoidut dialkyylitioeetterit
NO933084L (no)	1995-06-19	Kalkberedningsanlegg
ATA146094A (de)	1996-04-15	Windsichter
FI943385A0 (fi)	1994-07-15	Putkiurituslaite
DE59403503D1 (de)	1997-09-04	Substituierte 1-Aryltriazolinone
DE59309062D1 (de)	1998-11-19	Mischer-Trockner
ATA194593A (de)	1996-01-15	Sportschuh
ATA179094A (de)	1997-07-15	Kettenschloss
ATA212793A (de)	1996-01-15	Sportschuh
BR9405830A (pt)	1996-01-16	Oxazois substituidos
KR950005495U (ko)	1995-03-20	조립식 가구
DE59407752D1 (de)	1999-03-11	Durchlaufofen
ITRC930003A0 (it)	1993-03-29	Ecomat c
KR940022970U (ko)	1994-10-20	조립식 가구
NO931756L (no)	1994-11-15	Splitte/stableverktöy
FI993U1 (fi)	1993-11-10	Hushaollspostlaoda
FI1378U1 (fi)	1994-06-09	Bakningsprodukt
FI1198U1 (fi)	1994-02-15	Dubbelroder
ATE144907T1 (de)	1996-11-15	Rollbrett
BR7301059U (pt)	1993-11-03	Touca termica
BR9301760A (pt)	1994-11-08	Stressímetro
BR7301545U (pt)	1995-04-18	Jogo-ecologia
BR7300755U (pt)	1993-08-31	Music-dance-decoration
BR7301580U (pt)	1995-04-18	Teclimp