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FI931079A - Mikrobmotverkande karbapenemderivat, deras framstaellning och terapeutiska anvaendning - Google Patents

Mikrobmotverkande karbapenemderivat, deras framstaellning och terapeutiska anvaendning Download PDF

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Publication number
FI931079A
FI931079A FI931079A FI931079A FI931079A FI 931079 A FI931079 A FI 931079A FI 931079 A FI931079 A FI 931079A FI 931079 A FI931079 A FI 931079A FI 931079 A FI931079 A FI 931079A
Authority
FI
Finland
Prior art keywords
hydrogen
microbother
machinery
useful
acylimidoyl
Prior art date
Application number
FI931079A
Other languages
English (en)
Other versions
FI931079A0 (fi
FI103046B (fi
FI103046B1 (fi
Inventor
Isao Kawamoto
Rokuro Endo
Masao Miyauchi
Katsuya Ishikawa
Katsuhiko Watanabe
Hiroshi Yasuda
Satoshi Ohya
Yukio Utsui
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of FI931079A0 publication Critical patent/FI931079A0/fi
Publication of FI931079A publication Critical patent/FI931079A/fi
Application granted granted Critical
Publication of FI103046B publication Critical patent/FI103046B/fi
Publication of FI103046B1 publication Critical patent/FI103046B1/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI931079A 1992-03-11 1993-03-10 Menetelmä lääkeaineina käyttökelpoisten pyrrolidinyylitiokarbapeneemijohdannaisten valmistamiseksi FI103046B1 (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP5216392 1992-03-11
JP5216392 1992-03-11
JP24495392 1992-09-14
JP24495392 1992-09-14
JP24657892 1992-09-16
JP24657892 1992-09-16

Publications (4)

Publication Number Publication Date
FI931079A0 FI931079A0 (fi) 1993-03-10
FI931079A true FI931079A (fi) 1993-09-12
FI103046B FI103046B (fi) 1999-04-15
FI103046B1 FI103046B1 (fi) 1999-04-15

Family

ID=27294566

Family Applications (1)

Application Number Title Priority Date Filing Date
FI931079A FI103046B1 (fi) 1992-03-11 1993-03-10 Menetelmä lääkeaineina käyttökelpoisten pyrrolidinyylitiokarbapeneemijohdannaisten valmistamiseksi

Country Status (19)

Country Link
EP (1) EP0560613B1 (fi)
KR (1) KR100258225B1 (fi)
CN (1) CN1037180C (fi)
AT (1) ATE173733T1 (fi)
AU (1) AU664422B2 (fi)
CA (1) CA2091486A1 (fi)
CZ (1) CZ290002B6 (fi)
DE (1) DE69322188T2 (fi)
DK (1) DK0560613T3 (fi)
ES (1) ES2125945T3 (fi)
FI (1) FI103046B1 (fi)
HK (1) HK1011976A1 (fi)
HU (1) HU218676B (fi)
IL (1) IL105020A (fi)
MX (1) MX9301361A (fi)
NO (1) NO303730B1 (fi)
NZ (1) NZ247129A (fi)
RU (1) RU2097383C1 (fi)
TW (1) TW249803B (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ167792A3 (en) * 1991-06-04 1995-12-13 Sankyo Co 1-methylcarbapenem derivatives process of their preparation and use
GB9515975D0 (en) 1995-08-04 1995-10-04 Zeneca Ltd Chemical compounds
CZ298246B6 (cs) * 1995-12-21 2007-08-01 Sankyo Company Limited Deriváty 1-methylkarbapenu, zpusob jejich prípravy a farmaceutické prostredky, které je obsahují
WO1997041123A1 (fr) * 1996-04-26 1997-11-06 Sankyo Company, Limited Derives de 1-methylcarbapeneme
US6946468B1 (en) 1996-08-17 2005-09-20 Zeneca Limited 3-mercaptopyrrolidines as farnesyl protein transferase inhibitors
WO2000034282A1 (fr) * 1998-12-07 2000-06-15 Sankyo Company, Limited Derives de 1-methylcarbapenem
US7041660B2 (en) 1999-07-06 2006-05-09 Sankyo Company, Limited Crystalline 1-methylcarbapenem derivatives
GB9930317D0 (en) 1999-12-22 2000-02-09 Zeneca Ltd Novel compounds
GB9930318D0 (en) 1999-12-22 2000-02-09 Zeneca Ltd Novel compounds
CN100338064C (zh) * 2001-09-26 2007-09-19 默克公司 用于生产碳青霉烯化合物的方法
EP1698375B1 (en) * 2003-12-25 2014-04-02 Ono Pharmaceutical Co., Ltd. Azetidine ring compounds and drugs comprising the same
CN101367814B (zh) * 2007-06-28 2010-12-15 山东轩竹医药科技有限公司 被巯基吡咯烷甲酰哌啶取代的培南衍生物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1283906C (en) * 1983-05-09 1991-05-07 Makoto Sunagawa .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF
DE3780344T2 (de) * 1986-03-27 1993-01-28 Sumitomo Pharma Beta-lactam-verbindungen und deren herstellung.
CA2036163C (en) * 1990-02-14 2001-06-19 Makoto Sunagawa Novel beta-lactam compounds and their production
FI96863C (fi) * 1990-02-23 1996-09-10 Sankyo Co Menetelmä lääkeaineina käyttökelpoisten /2-(1-homopiperatsiinikarbonyyli)pyrrolidin-4-yylitio/-6-(1-hydroksietyyli)-1-karbapen-2-eemi-3-karboksylaattisuolojen valmistamiseksi
GB9107363D0 (en) * 1991-04-08 1991-05-22 Ici Plc Antibiotic compounds
CZ167792A3 (en) * 1991-06-04 1995-12-13 Sankyo Co 1-methylcarbapenem derivatives process of their preparation and use
AU3904493A (en) * 1992-04-13 1993-11-18 Fujisawa Pharmaceutical Co., Ltd. Substituted 3-pyrrolidinylthio-carbapenems as antimicrobial agents

Also Published As

Publication number Publication date
EP0560613B1 (en) 1998-11-25
ATE173733T1 (de) 1998-12-15
CZ290002B6 (cs) 2002-05-15
RU2097383C1 (ru) 1997-11-27
HU9300677D0 (en) 1993-05-28
CZ39393A3 (en) 1993-12-15
FI931079A0 (fi) 1993-03-10
FI103046B (fi) 1999-04-15
EP0560613A1 (en) 1993-09-15
NO930884L (no) 1993-09-13
DE69322188D1 (de) 1999-01-07
TW249803B (fi) 1995-06-21
KR930019674A (ko) 1993-10-18
AU3515193A (en) 1993-09-16
FI103046B1 (fi) 1999-04-15
MX9301361A (es) 1994-01-31
IL105020A (en) 1997-04-15
NO930884D0 (no) 1993-03-11
CN1037180C (zh) 1998-01-28
HK1011976A1 (en) 1999-07-23
HUT64071A (en) 1993-11-29
IL105020A0 (en) 1993-07-08
HU218676B (hu) 2000-10-28
AU664422B2 (en) 1995-11-16
NZ247129A (en) 1994-09-27
NO303730B1 (no) 1998-08-24
ES2125945T3 (es) 1999-03-16
CA2091486A1 (en) 1993-09-12
DK0560613T3 (da) 1999-08-09
KR100258225B1 (ko) 2000-08-01
DE69322188T2 (de) 1999-07-29
CN1079472A (zh) 1993-12-15

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Owner name: SANKYO COMPANY LIMITED