FI924077A0 - Nya omaettade acykliska purin- och pyrimidinfosfonatderivat. - Google Patents
Nya omaettade acykliska purin- och pyrimidinfosfonatderivat.Info
- Publication number
- FI924077A0 FI924077A0 FI924077A FI924077A FI924077A0 FI 924077 A0 FI924077 A0 FI 924077A0 FI 924077 A FI924077 A FI 924077A FI 924077 A FI924077 A FI 924077A FI 924077 A0 FI924077 A0 FI 924077A0
- Authority
- FI
- Finland
- Prior art keywords
- pyrimidinphosphonatderivat
- omaettade
- acykliska
- nya
- purin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6509—Six-membered rings
- C07F9/6512—Six-membered rings having the nitrogen atoms in positions 1 and 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP91402427A EP0531597A1 (en) | 1991-09-12 | 1991-09-12 | Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI924077A0 true FI924077A0 (fi) | 1992-09-11 |
| FI924077A FI924077A (fi) | 1993-03-13 |
Family
ID=8208612
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI924077A FI924077A (fi) | 1991-09-12 | 1992-09-11 | Nya omaettade acykliska purin- och pyrimidinfosfonatderivat |
Country Status (9)
| Country | Link |
|---|---|
| EP (2) | EP0531597A1 (fi) |
| JP (1) | JPH05247070A (fi) |
| KR (1) | KR930006036A (fi) |
| AU (1) | AU646758B2 (fi) |
| CA (1) | CA2078030A1 (fi) |
| FI (1) | FI924077A (fi) |
| HU (1) | HUT62009A (fi) |
| IL (1) | IL103125A0 (fi) |
| NO (1) | NO923539L (fi) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0618214A1 (en) * | 1993-04-01 | 1994-10-05 | Merrell Dow Pharmaceuticals Inc. | Unsaturated phosphonate derivatives of purines and pyrimidines |
| US5817647A (en) * | 1993-04-01 | 1998-10-06 | Merrell Pharmaceuticals Inc. | Unsaturated acetylene phosphonate derivatives of purines |
| CA2171868A1 (en) * | 1993-09-17 | 1995-03-23 | Petr Alexander | Method for dosing therapeutic compounds |
| US5656745A (en) * | 1993-09-17 | 1997-08-12 | Gilead Sciences, Inc. | Nucleotide analogs |
| US5798340A (en) | 1993-09-17 | 1998-08-25 | Gilead Sciences, Inc. | Nucleotide analogs |
| US5446045A (en) * | 1993-12-20 | 1995-08-29 | Revankar; Ganapathi R. | Antiviral guanine analogs |
| US5994321A (en) * | 1993-12-20 | 1999-11-30 | Aronex Pharmaceuticals, Inc. | Antiviral guanine analogs |
| EP1259520B1 (en) * | 1999-12-17 | 2006-05-24 | Ariad Pharmaceuticals, Inc. | Novel purines |
| IL150062A0 (en) | 1999-12-17 | 2002-12-01 | Ariad Pharma Inc | Proton pump inhibitors |
| CZ297267B6 (cs) * | 2001-06-29 | 2006-10-11 | Ústav organické chemie a biochemie AV CR | Deriváty pyrimidinu nesoucí fosfonátovou skupinu,zpusob jejich prípravy, jejich pouzití pro lécbu a farmaceutické prípravky tyto látky obsahující |
| JP2005523922A (ja) | 2002-04-26 | 2005-08-11 | ギリアード サイエンシーズ， インコーポレイテッド | 非ヌクレオシド逆転写酵素阻害剤 |
| ATE490788T1 (de) | 2003-04-25 | 2010-12-15 | Gilead Sciences Inc | Antivirale phosphonate analoge |
| US7452901B2 (en) | 2003-04-25 | 2008-11-18 | Gilead Sciences, Inc. | Anti-cancer phosphonate analogs |
| WO2004096285A2 (en) | 2003-04-25 | 2004-11-11 | Gilead Sciences, Inc. | Anti-infective phosphonate conjugates |
| US7470724B2 (en) | 2003-04-25 | 2008-12-30 | Gilead Sciences, Inc. | Phosphonate compounds having immuno-modulatory activity |
| US7432261B2 (en) | 2003-04-25 | 2008-10-07 | Gilead Sciences, Inc. | Anti-inflammatory phosphonate compounds |
| WO2004096287A2 (en) | 2003-04-25 | 2004-11-11 | Gilead Sciences, Inc. | Inosine monophosphate dehydrogenase inhibitory phosphonate compounds |
| US7407965B2 (en) | 2003-04-25 | 2008-08-05 | Gilead Sciences, Inc. | Phosphonate analogs for treating metabolic diseases |
| CA2522845A1 (en) | 2003-04-25 | 2004-11-11 | Gilead Sciences, Inc. | Kinase inhibitor phosphonate conjugates |
| WO2005002626A2 (en) | 2003-04-25 | 2005-01-13 | Gilead Sciences, Inc. | Therapeutic phosphonate compounds |
| NZ544988A (en) | 2003-07-30 | 2009-11-27 | Gilead Sciences Inc | Nucleobase phosphonate analogs for antiviral treatment |
| WO2005044308A1 (en) | 2003-10-24 | 2005-05-19 | Gilead Sciences, Inc. | Phosphonate analogs of antimetabolites |
| WO2005044279A1 (en) * | 2003-10-24 | 2005-05-19 | Gilead Sciences, Inc. | Purine nucleoside phosphonate conjugates |
| EP1680512A1 (en) | 2003-10-24 | 2006-07-19 | Gilead Sciences, Inc. | Methods and compositions for identifying therapeutic compounds |
| KR20060127906A (ko) | 2003-12-22 | 2006-12-13 | 길리애드 사이언시즈, 인코포레이티드 | 4'-치환된 카보버와 아바카비어 유도체 및 ｈｉｖ와 ｈｃｖ항바이러스 활성을 갖는 관련 화합물 |
| EP1778251B1 (en) | 2004-07-27 | 2011-04-13 | Gilead Sciences, Inc. | Nucleoside phosphonate conjugates as anti hiv agents |
| EP1866319B1 (en) * | 2005-04-01 | 2011-11-23 | The Regents of The University of California | Phosphono-pent-2-en-1-yl nucleosides and analogs |
| WO2007014352A2 (en) * | 2005-07-27 | 2007-02-01 | Gilead Sciences, Inc. | Antiviral phosphonate conjugates for inhibition of hiv |
| WO2008100447A2 (en) | 2007-02-09 | 2008-08-21 | Gilead Sciences, Inc. | Nucleoside analogs for antiviral treatment |
| ES2393962T3 (es) | 2008-07-08 | 2013-01-03 | Gilead Sciences, Inc. | Sales de compuestos inhibidores del VIH. |
| ES2734495T3 (es) | 2011-12-22 | 2019-12-10 | Geron Corp | Análogos de guanina como sustratos de telomerasa y afectores de la longitud de los telómeros |
| PT3661937T (pt) | 2017-08-01 | 2021-09-24 | Gilead Sciences Inc | Formas cristalinas de ((s)-((((2r,5r)-5-(6-amino-9h-purin-9-il)-4-fluoro-2,5-dihidrofurano-2-il)oxi)metil)(fenoxi)fosforil)-l-alaninato de etil (gs-9131) para tratamento de infeções virais |
| EP3691657A4 (en) | 2017-10-04 | 2021-07-21 | Avidity Biosciences, Inc. | NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF |
| WO2019136180A2 (en) * | 2018-01-04 | 2019-07-11 | Avidity Biosciences Llc | Heteroduplex nucleic acid molecules and uses thereof |
| EP3784680A1 (en) * | 2018-04-23 | 2021-03-03 | Centre national de la recherche scientifique | New antiviral acyclonucleoside analogues |
| US11578090B2 (en) | 2019-06-06 | 2023-02-14 | Avidity Biosciences, Inc. | Nucleic acid-polypeptide compositions and uses thereof |
| WO2020247818A1 (en) | 2019-06-06 | 2020-12-10 | Avidity Biosciences, Inc. | Una amidites and uses thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0353955A3 (en) * | 1988-08-02 | 1991-08-14 | Beecham Group Plc | Novel compounds |
| ES2085446T3 (es) * | 1990-07-04 | 1996-06-01 | Merrell Pharma Inc | Derivados de acido 9-purinil fosfonico. |
| US5356886A (en) * | 1990-07-19 | 1994-10-18 | Beecham Group P.L.C. | Antiviral phosphono-alken derivatives of purines |
-
1991
- 1991-09-12 EP EP91402427A patent/EP0531597A1/en not_active Withdrawn
-
1992
- 1992-09-08 AU AU22197/92A patent/AU646758B2/en not_active Ceased
- 1992-09-09 KR KR1019920016534A patent/KR930006036A/ko not_active Application Discontinuation
- 1992-09-10 IL IL103125A patent/IL103125A0/xx unknown
- 1992-09-11 CA CA002078030A patent/CA2078030A1/en not_active Abandoned
- 1992-09-11 EP EP92402487A patent/EP0532423A1/en not_active Withdrawn
- 1992-09-11 HU HU9202924A patent/HUT62009A/hu unknown
- 1992-09-11 FI FI924077A patent/FI924077A/fi unknown
- 1992-09-11 JP JP4267791A patent/JPH05247070A/ja active Pending
- 1992-09-11 NO NO92923539A patent/NO923539L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUT62009A (en) | 1993-03-29 |
| AU646758B2 (en) | 1994-03-03 |
| FI924077A (fi) | 1993-03-13 |
| KR930006036A (ko) | 1993-04-20 |
| NO923539L (no) | 1993-03-15 |
| NO923539D0 (no) | 1992-09-11 |
| EP0532423A1 (en) | 1993-03-17 |
| AU2219792A (en) | 1993-03-18 |
| CA2078030A1 (en) | 1993-03-13 |
| JPH05247070A (ja) | 1993-09-24 |
| IL103125A0 (en) | 1993-02-21 |
| EP0531597A1 (en) | 1993-03-17 |
| HU9202924D0 (en) | 1992-11-30 |
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