FI881877A0 - 17 -(cyklopropylamino) androst-5 -en-3 -ol och naerstaoende foereningar, som aer anvaendbara som c17-20-lyas-inhibitorer. - Google Patents

17 -(cyklopropylamino) androst-5 -en-3 -ol och naerstaoende foereningar, som aer anvaendbara som c17-20-lyas-inhibitorer.

Info

Publication number: FI881877A0
Authority: FI; Finland
Prior art keywords: som; androst; cyclopropylamino; inhibitorer; lyas
Prior art date: 1987-04-22

Application number

FI881877A

Other languages

English (en)

Other versions

FI881877A (fi

FI88397B (fi

FI88397C (fi

Inventor

Michael R Angelastro

Thomas R Blohm

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-04-22

Filing date

1988-04-21

Publication date

1988-04-21

1988-04-21 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1988-04-21 Publication of FI881877A0 publication Critical patent/FI881877A0/fi

1988-10-23 Publication of FI881877A publication Critical patent/FI881877A/fi

1993-01-29 Publication of FI88397B publication Critical patent/FI88397B/fi

1993-05-10 Application granted granted Critical

1993-05-10 Publication of FI88397C publication Critical patent/FI88397C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Urology & Nephrology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Epidemiology (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Enzymes And Modification Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Detergent Compositions (AREA)

FI881877A 1987-04-22 1988-04-21 Foerfarande foer framstaellning av 17 -(cyklopropylamino)androst-5-en-3 -ol och naestaende foereningar, som aer anvaendbara som c17-20-lyas in hibitorer FI88397C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US4117287A	1987-04-22	1987-04-22
US4117287		1987-04-22

Publications (4)

Publication Number	Publication Date
FI881877A0 true FI881877A0 (fi)	1988-04-21
FI881877A FI881877A (fi)	1988-10-23
FI88397B FI88397B (fi)	1993-01-29
FI88397C FI88397C (fi)	1993-05-10

Family

ID=21915133

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI881877A FI88397C (fi)	1987-04-22	1988-04-21	Foerfarande foer framstaellning av 17 -(cyklopropylamino)androst-5-en-3 -ol och naestaende foereningar, som aer anvaendbara som c17-20-lyas in hibitorer

Country Status (19)

Country	Link
EP (1)	EP0288053B1 (fi)
JP (1)	JP2711672B2 (fi)
KR (1)	KR960015037B1 (fi)
CN (1)	CN88102176A (fi)
AT (1)	ATE67211T1 (fi)
AU (1)	AU606677B2 (fi)
CA (1)	CA1326234C (fi)
DE (1)	DE3864725D1 (fi)
DK (1)	DK217588A (fi)
ES (1)	ES2038712T3 (fi)
FI (1)	FI88397C (fi)
GR (1)	GR3002713T3 (fi)
HU (1)	HU198511B (fi)
IL (1)	IL86139A (fi)
NO (1)	NO169346C (fi)
NZ (1)	NZ224288A (fi)
PH (1)	PH24090A (fi)
PT (1)	PT87294B (fi)
ZA (1)	ZA882717B (fi)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4891367A (en) *	1987-04-22	1990-01-02	Merrell Dow Pharmaceuticals Inc.	17β-(cyclopropyloxy)androst-5-en-3β-ol and related compounds useful as C17-20 lyase inhibitors
US4954488A (en) *	1989-06-14	1990-09-04	Merrell Dow Pharmaceuticals Inc.	Method of treating hyperaldosteronism using 17β-cyclopropylaminoandrostene derivatives
US4966898A (en) *	1989-08-15	1990-10-30	Merrell Dow Pharmaceuticals Inc.	4-substituted 17β-(cyclopropylamino)androst-5-en-3β-ol and related compounds useful as C17-20 lyase inhibitors
US5252319A (en) *	1990-06-12	1993-10-12	Insite Vision Incorporated	Aminosteroids for ophthalmic use
US5124154A (en) *	1990-06-12	1992-06-23	Insite Vision Incorporated	Aminosteroids for ophthalmic use
US5256408A (en) *	1990-06-12	1993-10-26	Insite Vision Incorporated	Aminosteroids for ophthalmic use
US5209926A (en) *	1990-06-12	1993-05-11	Insite Vision Incorporated	Aminosteroids for ophthalmic use
NZ249911A (en) *	1992-03-31	1996-06-25	British Tech Group	17-(3-pyridyl) substituted steroids and use in pharmaceutical compositions
US5604213A (en) *	1992-03-31	1997-02-18	British Technology Group Limited	17-substituted steroids useful in cancer treatment
US5486511A (en) *	1993-05-25	1996-01-23	Merrell Dow Pharmaceuticals Inc.	4-amino-17β-(cyclopropyloxy)androst-4-en-3-one, 4-amino-17β-(cyclopropylamino)androst-4-en-3-one and related compounds as C17-20 lyase and 5α-reductase
DE60119963T2 (de)	2000-11-17	2006-10-05	Takeda Pharmaceutical Co. Ltd.	Imidazol derivate, ihre herstellung und ihre verwendung
EP1344777B1 (en)	2000-11-20	2011-03-16	Takeda Pharmaceutical Company Limited	Imidazole derivatives, process for their preparation and their use
DE60139639D1 (de)	2000-12-08	2009-10-01	Takeda Pharmaceutical	Substituierte thiazolderivate mit 3-pyridylgruppen, verfahren zu deren herstellung und deren verwendung
JO2892B1 (en)	2009-06-26	2015-09-15	نوفارتيس ايه جي	CYP inhibitors 17
CA2807149C (en)	2010-08-04	2017-05-02	Pellficure Pharmaceuticals, Inc.	Novel treatment of prostate carcinoma
US8946260B2 (en)	2010-09-16	2015-02-03	Novartis Ag	17α-hydroxylase/C17,20-lyase inhibitors
CA2834224A1 (en)	2011-04-28	2012-11-01	Novartis Ag	17.alpha.-hydroxylase/c17,20-lyase inhibitors
US20160022606A1 (en)	2013-03-14	2016-01-28	Pellficure Pharmaceuticals Inc.	Novel therapy for prostate carcinoma
EP3191087A1 (en)	2014-09-12	2017-07-19	Pellficure Pharmaceuticals, Inc.	Compositions and methods for treatment of prostate carcinoma
WO2018080933A1 (en)	2016-10-24	2018-05-03	Pellficure Pharmaceuticals Inc.	Pharmaceutical compositions of 5-hydroxy-2-methylnaphthalene-1, 4-dione

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL302932A (fi) *	1962-12-31
US4891367A (en) *	1987-04-22	1990-01-02	Merrell Dow Pharmaceuticals Inc.	17β-(cyclopropyloxy)androst-5-en-3β-ol and related compounds useful as C17-20 lyase inhibitors

1988
- 1988-04-18 ZA ZA882717A patent/ZA882717B/xx unknown
- 1988-04-18 NZ NZ224288A patent/NZ224288A/xx unknown
- 1988-04-18 AU AU14719/88A patent/AU606677B2/en not_active Ceased
- 1988-04-18 CA CA000564364A patent/CA1326234C/en not_active Expired - Fee Related
- 1988-04-19 PH PH36817A patent/PH24090A/en unknown
- 1988-04-20 IL IL86139A patent/IL86139A/xx unknown
- 1988-04-21 AT AT88106397T patent/ATE67211T1/de not_active IP Right Cessation
- 1988-04-21 FI FI881877A patent/FI88397C/fi not_active IP Right Cessation
- 1988-04-21 CN CN198888102176A patent/CN88102176A/zh active Pending
- 1988-04-21 KR KR1019880004512A patent/KR960015037B1/ko not_active IP Right Cessation
- 1988-04-21 JP JP63096969A patent/JP2711672B2/ja not_active Expired - Fee Related
- 1988-04-21 DE DE8888106397T patent/DE3864725D1/de not_active Expired - Fee Related
- 1988-04-21 NO NO881746A patent/NO169346C/no unknown
- 1988-04-21 DK DK217588A patent/DK217588A/da not_active Application Discontinuation
- 1988-04-21 PT PT87294A patent/PT87294B/pt not_active IP Right Cessation
- 1988-04-21 ES ES198888106397T patent/ES2038712T3/es not_active Expired - Lifetime
- 1988-04-21 HU HU882029A patent/HU198511B/hu not_active IP Right Cessation
- 1988-04-21 EP EP88106397A patent/EP0288053B1/en not_active Expired - Lifetime
1991
- 1991-09-12 GR GR91401315T patent/GR3002713T3/el unknown

Also Published As

Publication number	Publication date
EP0288053A1 (en)	1988-10-26
ZA882717B (en)	1988-10-17
FI881877A (fi)	1988-10-23
CA1326234C (en)	1994-01-18
NZ224288A (en)	1989-12-21
GR3002713T3 (en)	1993-01-25
NO169346B (no)	1992-03-02
ATE67211T1 (de)	1991-09-15
NO881746D0 (no)	1988-04-21
PT87294B (pt)	1992-08-31
DK217588D0 (da)	1988-04-21
DE3864725D1 (de)	1991-10-17
AU1471988A (en)	1988-10-27
EP0288053B1 (en)	1991-09-11
IL86139A (en)	1993-02-21
NO881746L (no)	1988-10-24
IL86139A0 (en)	1988-11-15
JP2711672B2 (ja)	1998-02-10
KR960015037B1 (ko)	1996-10-24
ES2038712T3 (es)	1993-08-01
DK217588A (da)	1988-10-23
AU606677B2 (en)	1991-02-14
FI88397B (fi)	1993-01-29
HUT47307A (en)	1989-02-28
KR880012633A (ko)	1988-11-28
FI88397C (fi)	1993-05-10
PT87294A (pt)	1988-05-01
JPS63284195A (ja)	1988-11-21
NO169346C (no)	1992-06-10
HU198511B (en)	1989-10-30
PH24090A (en)	1990-03-05
CN88102176A (zh)	1988-11-23

Publication	Publication Date	Title
FI881877A (fi)	1988-10-23	17 -(cyklopropylamino) androst-5 -en-3 -ol och naerstaoende foereningar, som aer anvaendbara som c17-20-lyas-inhibitorer.
LTIP919A (en)	1995-03-27	Drugs and process for preparing thereof
NO903564L (no)	1991-02-18	Fremgangsmaate for fremstilling av 4-substituerte 17beta-(cyklopropylamino)androst-5-en-3beta-ol-derivater.
ATE38036T1 (de)	1988-11-15	Benzothiophenderivate als bronchodilatoren.
FI881878A (fi)	1988-10-23	17 -(cyklopropyloxi) androst-5-en -3 -ol och naerstaoende foereningar, som aer anvaendbara som c17-20 lyas inhibitorer.
DK0655243T3 (da)	2002-10-07	Melatoninderivater til anvendelse ved behandling af søvnlidelser
EP0319962A3 (en)	1990-08-22	Piperidinyl methanol derivatives for the treatment of anxiety
DE69432626D1 (de)	2003-06-12	Melatonin-Derivate zur Verwendung in der Behandlung von Desynchronisierungs-Erkankungen
NO903338L (no)	1991-01-29	Fremgangsmaate for mikrobiologisk fremstilling av l-carnitin.
FI903143A0 (fi)	1990-06-21	Menetelmä ihmisen nuhaviruksen serotyypittämiseksi
EP0253650A3 (en)	1989-09-13	Improvements relating to benzothiophene derivatives

Legal Events

Date	Code	Title	Description
1993-01-04	BB	Publication of examined application
1994-04-21	MM	Patent lapsed
2004-08-31	MM	Patent lapsed	Owner name: MERRELL DOW PHARMACEUTICALS INC.