FI875235A - Menetelmä valmistaa terapeuttisesti aktiivisia tetrahydro(imidatsolyylimetyyli)-4H-karbatsol-4-oneja - Google Patents

Menetelmä valmistaa terapeuttisesti aktiivisia tetrahydro(imidatsolyylimetyyli)-4H-karbatsol-4-oneja Download PDF

Info

Publication number: FI875235A
Authority: FI; Finland
Prior art keywords: imidazolylmethyl; carbazol; preparation; therapeutically active; active tetrahydro
Prior art date: 1986-11-28

Application number

FI875235A

Other languages

English (en)

Swedish (sv)

Other versions

FI875235A0 (fi

FI92062B (fi

FI92062C (fi

Inventor

Ian Harold Coates

John Bradshaw

James Angus Bell

David Cedric Humber

George Blanch Ewan

William Leonard Mitchell

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-11-28

Filing date

1987-11-27

Publication date

1988-05-29

1986-11-28 Priority claimed from GB868628473A external-priority patent/GB8628473D0/en

1987-11-12 Priority claimed from GB878726537A external-priority patent/GB8726537D0/en

1987-11-27 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

1987-11-27 Publication of FI875235A0 publication Critical patent/FI875235A0/fi

1988-05-29 Publication of FI875235A publication Critical patent/FI875235A/fi

1994-06-15 Publication of FI92062B publication Critical patent/FI92062B/fi

1994-09-26 Application granted granted Critical

1994-09-26 Publication of FI92062C publication Critical patent/FI92062C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

FI875235A 1986-11-28 1987-11-27 Menetelmä valmistaa terapeuttisesti aktiivisia tetrahydro(imidatsolyylimetyyli)-4H-karbatsol-4-oneja FI92062C (fi)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GB868628473A GB8628473D0 (en)	1986-11-28	1986-11-28	Chemical compounds
GB8628473		1986-11-28
GB878726537A GB8726537D0 (en)	1987-11-12	1987-11-12	Tricyclic ketones
GB8726537		1987-11-12

Publications (4)

Publication Number	Publication Date
FI875235A0 FI875235A0 (fi)	1987-11-27
FI875235A true FI875235A (fi)	1988-05-29
FI92062B FI92062B (fi)	1994-06-15
FI92062C FI92062C (fi)	1994-09-26

Family

ID=26291603

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI875235A FI92062C (fi)	1986-11-28	1987-11-27	Menetelmä valmistaa terapeuttisesti aktiivisia tetrahydro(imidatsolyylimetyyli)-4H-karbatsol-4-oneja

Country Status (24)

Country	Link
US (1)	US4822881A (fi)
AT (1)	AT396933B (fi)
AU (1)	AU605805B2 (fi)
BE (1)	BE1001004A4 (fi)
CA (1)	CA1326032C (fi)
CH (1)	CH676120A5 (fi)
CZ (1)	CZ404591A3 (fi)
DE (1)	DE3740352A1 (fi)
DK (1)	DK169675B1 (fi)
ES (1)	ES2008360A6 (fi)
FI (1)	FI92062C (fi)
FR (1)	FR2611366B1 (fi)
GB (1)	GB2202530B (fi)
GR (1)	GR871809B (fi)
HK (1)	HK51591A (fi)
IE (1)	IE61510B1 (fi)
IL (1)	IL84635A (fi)
IT (1)	IT1211936B (fi)
NL (1)	NL8702851A (fi)
NO (1)	NO172581C (fi)
NZ (1)	NZ222725A (fi)
PH (1)	PH30436A (fi)
SE (1)	SE467255B (fi)
SG (1)	SG46591G (fi)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8518742D0 (en) *	1985-07-24	1985-08-29	Glaxo Group Ltd	Process
GB8812002D0 (en) *	1988-05-20	1988-06-22	Glaxo Group Ltd	Chemical compounds
US5202343A (en) *	1986-11-28	1993-04-13	Glaxo Group Limited	Tricyclic ketones useful as HT3 -receptor antagonists
DE3822792C2 (de) *	1987-07-11	1997-11-27	Sandoz Ag	Neue Verwendung von 5HT¶3¶-Antagonisten
GB8720693D0 (en) *	1987-09-03	1987-10-07	Glaxo Group Ltd	Chemical compounds
US5360800A (en) *	1987-09-03	1994-11-01	Glaxo Group Limited	Tetrahydro-1H-pyrido[4,3-b]indol-1-one derivatives
EP0317088A1 (en) *	1987-10-22	1989-05-24	Glaxo Group Limited	Ketone derivatives
US5116984A (en) *	1988-04-07	1992-05-26	Glaxo Group Limited	Imidazole derivatives
DK185489A (da) *	1988-04-22	1989-10-23	Duphar Int Res	Imidazolylmethyl-cycloalkanoebaaindoloner, deres fremstilling og anvendelse
EP0339959A3 (en) *	1988-04-27	1991-03-20	Glaxo Group Limited	Lactam derivatives
GB8812636D0 (en) *	1988-05-27	1988-06-29	Glaxo Group Ltd	Chemical compounds
EP0350129A1 (en) *	1988-07-07	1990-01-10	Duphar International Research B.V	New annelated indoleketones with an imidazolylalkyl substituent
HU207078B (en) *	1988-08-02	1993-03-01	Glaxo Group Ltd	Process for producing lactam derivatives and pharmaceutical compositions comprising such compounds
DK169922B1 (da) *	1988-08-02	1995-04-03	Glaxo Group Ltd	Substituerede (imidazol-4-yl)methylpyrido-, og -azepino-, indolonderivater, fremgangsmåde til fremstilling deraf samt farmaceutiske præparater indeholdende derivaterne
JPH02167280A (ja) *	1988-08-15	1990-06-27	Glaxo Group Ltd	ラクタム誘導体
EP0357417A1 (en) *	1988-09-01	1990-03-07	Glaxo Group Limited	Lactam derivatives
GB8820650D0 (en) *	1988-09-01	1988-10-05	Glaxo Group Ltd	Medicaments
GB8820651D0 (en) *	1988-09-01	1988-10-05	Glaxo Group Ltd	Medicaments
GB8820653D0 (en) *	1988-09-01	1988-10-05	Glaxo Group Ltd	Medicaments
AU627221B2 (en) *	1988-09-27	1992-08-20	Fujisawa Pharmaceutical Co., Ltd.	Pyridoindole derivatives and processes for preparation thereof
GB8823980D0 (en) *	1988-10-13	1988-11-23	Glaxo Group Ltd	Chemical compounds
US5223625A (en) *	1988-12-22	1993-06-29	Duphar International Research B.V.	Annelated indolo [3,2,-C]lactams
GB8904551D0 (en) *	1989-02-28	1989-04-12	Glaxo Group Ltd	Chemical compounds
GB8904552D0 (en)	1989-02-28	1989-04-12	Glaxo Group Ltd	Chemical process
HU204049B (en) *	1989-02-28	1991-11-28	Glaxo Group Ltd	Process for producing lactam derivatives and pharmaceutical compositions comprising same
WO1990012569A1 (en)	1989-04-21	1990-11-01	Sandoz Ag	Therapeutic use of 5-ht3 receptor antagonists
GB8928208D0 (en) *	1989-12-13	1990-02-14	Glaxo Group Ltd	Medicaments
HU211081B (en) *	1990-12-18	1995-10-30	Sandoz Ag	Process for producing indole derivatives as serotonin antagonists and pharmaceutical compositions containing the same
KR100368895B1 (ko) *	2000-03-30	2003-01-24	하나제약 주식회사	1,2,3,9-테트라하이드로-9-메틸-3-[(2-메틸-1ｈ-이미다졸-1-일)메틸]-4ｈ-카바졸-4-온의 제조방법
CA2473392A1 (en) *	2002-01-18	2003-07-31	Aryx Therapeutics	5-ht3 receptor antagonists and methods of use
ES2432618T3 (es)	2009-05-20	2013-12-04	Inserm (Institut National De La Santé Et De La Recherche Medicale)	Antagonistas del receptor 5-HT3 de serotonina para usar en el tratamiento o prevención de una patología del oído interno con déficit vestibular
CA2761762C (en)	2009-05-20	2018-09-04	Inserm (Institut National De La Sante Et De La Recherche Medicale)	Serotonin 5-ht3 receptor antagonists for use in the treatment of lesional vestibular disorders

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3634420A (en) *	1969-05-09	1972-01-11	American Cyanamid Co	3(morpholinomethyl)-2 3-dihydro-carbazol-4(1h)-ones
US3740404A (en) *	1969-05-09	1973-06-19	American Cyanamid Co	Piperidinomethylenedihydrocarbazolones
GB1365296A (en) *	1970-10-30	1974-08-29	Unilever Ltd	Dentifrice compositions
US4176230A (en) *	1977-08-04	1979-11-27	Hoffmann-La Roche Inc.	5-(6-Alkylindol-3-ylmethylene)-1,3-dimethyl-2-(methylimino)-4-imidazolidinones
PH14576A (en) *	1978-11-01	1981-09-24	Wellcome Found	9-(3-(3,5-cis-dimethylpiperazino)prophyl)carrazole,salts and solvates thereof and pharmaceutical compositions containing same
DK151884C (da) *	1979-03-07	1988-06-13	Pfizer	Analogifremgangsmaade til fremstilling af 3-(1-imidazolylalkyl)indolderivater eller farmaceutisk acceptable syreadditionssalte deraf
BE901576A (fr) *	1984-01-25	1985-07-25	Glaxo Group Ltd	Composes heterocycliques.
US4695578A (en) *	1984-01-25	1987-09-22	Glaxo Group Limited	1,2,3,9-tetrahydro-3-imidazol-1-ylmethyl-4H-carbazol-4-ones, composition containing them, and method of using them to treat neuronal 5HT function disturbances
DE3680123D1 (en) *	1985-01-23	1991-08-14	Glaxo Group Ltd	Tetrahydrocarbazolonderivate.
GB8518741D0 (en) *	1985-07-24	1985-08-29	Glaxo Group Ltd	Process
GB8518745D0 (en) *	1985-07-24	1985-08-29	Glaxo Group Ltd	Heterocyclic compounds
GB8518743D0 (en) *	1985-07-24	1985-08-29	Glaxo Group Ltd	Heterocyclic compounds

1987
- 1987-11-26 GR GR871809A patent/GR871809B/el unknown
- 1987-11-27 CA CA000552963A patent/CA1326032C/en not_active Expired - Fee Related
- 1987-11-27 US US07/126,202 patent/US4822881A/en not_active Expired - Fee Related
- 1987-11-27 CH CH4614/87A patent/CH676120A5/fr not_active IP Right Cessation
- 1987-11-27 DE DE19873740352 patent/DE3740352A1/de not_active Ceased
- 1987-11-27 GB GB8727835A patent/GB2202530B/en not_active Expired - Fee Related
- 1987-11-27 BE BE8701353A patent/BE1001004A4/fr not_active IP Right Cessation
- 1987-11-27 IT IT8748642A patent/IT1211936B/it active
- 1987-11-27 NO NO874959A patent/NO172581C/no unknown
- 1987-11-27 ES ES8703405A patent/ES2008360A6/es not_active Expired
- 1987-11-27 AT AT0312487A patent/AT396933B/de not_active IP Right Cessation
- 1987-11-27 IE IE323287A patent/IE61510B1/en not_active IP Right Cessation
- 1987-11-27 AU AU81845/87A patent/AU605805B2/en not_active Ceased
- 1987-11-27 NL NL8702851A patent/NL8702851A/nl not_active Application Discontinuation
- 1987-11-27 DK DK624887A patent/DK169675B1/da active
- 1987-11-27 IL IL84635A patent/IL84635A/xx not_active IP Right Cessation
- 1987-11-27 PH PH36132A patent/PH30436A/en unknown
- 1987-11-27 SE SE8704746A patent/SE467255B/sv not_active IP Right Cessation
- 1987-11-27 FI FI875235A patent/FI92062C/fi not_active IP Right Cessation
- 1987-11-27 NZ NZ222725A patent/NZ222725A/xx unknown
- 1987-11-27 FR FR878716488A patent/FR2611366B1/fr not_active Expired - Fee Related
1991
- 1991-06-18 SG SG46591A patent/SG46591G/en unknown
- 1991-07-04 HK HK515/91A patent/HK51591A/xx not_active IP Right Cessation
- 1991-12-23 CZ CS914045A patent/CZ404591A3/cs unknown

Also Published As

Publication number	Publication date
SE8704746D0 (sv)	1987-11-27
DK624887A (da)	1988-05-29
SG46591G (en)	1991-07-26
SE8704746L (sv)	1988-05-29
NL8702851A (nl)	1988-06-16
IT1211936B (it)	1989-11-08
IT8748642A0 (it)	1987-11-27
US4822881A (en)	1989-04-18
PH30436A (en)	1997-05-09
IL84635A (en)	1993-01-31
FR2611366B1 (fr)	1990-03-16
NO874959L (no)	1988-05-30
GR871809B (en)	1988-03-07
FR2611366A1 (fr)	1988-09-02
HK51591A (en)	1991-07-12
FI875235A0 (fi)	1987-11-27
DE3740352A1 (de)	1988-06-09
NO172581C (no)	1993-08-11
NO172581B (no)	1993-05-03
NO874959D0 (no)	1987-11-27
DK624887D0 (da)	1987-11-27
SE467255B (sv)	1992-06-22
AU8184587A (en)	1988-06-02
IE61510B1 (en)	1994-11-16
ATA312487A (de)	1993-05-15
GB2202530A (en)	1988-09-28
BE1001004A4 (fr)	1989-06-06
CA1326032C (en)	1994-01-11
CZ404591A3 (en)	1993-08-11
FI92062B (fi)	1994-06-15
GB8727835D0 (en)	1987-12-31
AU605805B2 (en)	1991-01-24
DK169675B1 (da)	1995-01-09
IL84635A0 (en)	1988-04-29
GB2202530B (en)	1990-04-18
IE873232L (en)	1988-05-28
NZ222725A (en)	1990-08-28
FI92062C (fi)	1994-09-26
CH676120A5 (fi)	1990-12-14
AT396933B (de)	1993-12-27
ES2008360A6 (es)	1989-07-16

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Legal Events

Date	Code	Title	Description
1994-05-16	BB	Publication of examined application
1998-11-27	MM	Patent lapsed
2004-08-31	MM	Patent lapsed	Owner name: GLAXO GROUP LIMITED