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FI860842A - Labdan-derivat, foerfarande foer deras framstaellning och deras anvaendning som laekemedel. - Google Patents

Labdan-derivat, foerfarande foer deras framstaellning och deras anvaendning som laekemedel. Download PDF

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Publication number
FI860842A
FI860842A FI860842A FI860842A FI860842A FI 860842 A FI860842 A FI 860842A FI 860842 A FI860842 A FI 860842A FI 860842 A FI860842 A FI 860842A FI 860842 A FI860842 A FI 860842A
Authority
FI
Finland
Prior art keywords
deras
labdan
derivat
foerfarande foer
framstaellning och
Prior art date
Application number
FI860842A
Other languages
English (en)
Other versions
FI860842A0 (fi
Inventor
Jr Raymond W Kosley
Robert J Cherill
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of FI860842A0 publication Critical patent/FI860842A0/fi
Publication of FI860842A publication Critical patent/FI860842A/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/92Naphthopyrans; Hydrogenated naphthopyrans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65502Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a three-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fire-Extinguishing Compositions (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Lubricants (AREA)
  • Ink Jet (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FI860842A 1985-03-01 1986-02-27 Labdan-derivat, foerfarande foer deras framstaellning och deras anvaendning som laekemedel. FI860842A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US70728385A 1985-03-01 1985-03-01

Publications (2)

Publication Number Publication Date
FI860842A0 FI860842A0 (fi) 1986-02-27
FI860842A true FI860842A (fi) 1986-09-02

Family

ID=24841093

Family Applications (1)

Application Number Title Priority Date Filing Date
FI860842A FI860842A (fi) 1985-03-01 1986-02-27 Labdan-derivat, foerfarande foer deras framstaellning och deras anvaendning som laekemedel.

Country Status (15)

Country Link
EP (1) EP0193132B1 (fi)
JP (1) JPS61210081A (fi)
KR (1) KR910007967B1 (fi)
AT (1) ATE62683T1 (fi)
AU (1) AU577928B2 (fi)
DE (1) DE3678736D1 (fi)
DK (1) DK92786A (fi)
ES (4) ES8705414A1 (fi)
FI (1) FI860842A (fi)
GR (1) GR860571B (fi)
HU (1) HUT42080A (fi)
NO (1) NO860758L (fi)
PH (1) PH23778A (fi)
PT (1) PT82097B (fi)
ZA (1) ZA861505B (fi)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE60767T1 (de) * 1984-12-14 1991-02-15 Hoechst Roussel Pharma Aminoacyllabdane, verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung als arzneimittel.
IN163242B (fi) 1985-05-03 1988-08-27 Hoechst India
JPS6310783A (ja) * 1985-11-15 1988-01-18 Nippon Kayaku Co Ltd 新規フオルスコリン誘導体
AU591196B2 (en) * 1985-11-15 1989-11-30 Nippon Kayaku Kabushiki Kaisha Novel forskolin derivatives
US4740522A (en) * 1986-08-28 1988-04-26 Hoechst-Roussel Pharmaceuticals Inc. Oxolabdanes useful as pharmaceuticals for reducing intraocular pressure
US5247097A (en) * 1986-08-28 1993-09-21 Hoechst-Roussel Pharmaceuticals Incorporated Oxolabdanes
US5646175A (en) * 1987-12-28 1997-07-08 Hoechst Marion Roussel, Inc. Carbamoyloxylabdane compounds
US4920146A (en) * 1986-12-29 1990-04-24 Hoechst Roussel Pharmaceuticals Inc. Carbamoyloxylabdane compounds useful in reducing intraocular pressure
CA1307530C (en) * 1986-12-29 1992-09-15 Hoechst-Roussel Pharmaceuticals Inc. Carbamoyloxylabdanes, intermediates and a process for the preparation thereof and their use as medicaments
JPH0684367B2 (ja) * 1987-06-29 1994-10-26 日本化薬株式会社 フオルスコリン誘導体の新規製造法
US5302730A (en) * 1987-06-29 1994-04-12 Nippon Kayaku Kk Process for the preparation of 6,7-diacyl-7-deacetylforskolin derivatives
JP2504934B2 (ja) * 1987-06-29 1996-06-05 日本化薬株式会社 1,6,7−トリアシルフオルスコリン誘導体
US4902696A (en) * 1987-10-08 1990-02-20 Hoechst-Roussel Pharmaceuticals, Inc. Synergistic intraocular pressure lowering combinations
US5846992A (en) * 1987-10-08 1998-12-08 Hoechst Marion Roussel, Inc. Synergistic intraocular pressure lowering combinations
DE3737353A1 (de) * 1987-11-04 1989-05-18 Hoechst Ag Neue acyllabdan-derivate, ein verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
IN168181B (fi) * 1987-12-01 1991-02-16 Hoechst India
US4883793A (en) * 1988-05-09 1989-11-28 Hoechst-Roussel Pharmaceuticals Inc. Hydrazinocarbonyloxylabdanes for treating cardiac failure
US5051132A (en) * 1989-06-15 1991-09-24 Nippon Kayaku Kabushiki Kaisha Lyophilized preparation of 6-(3-dimethylaminopropionyl)forskolin
US5093336A (en) * 1989-07-06 1992-03-03 Hoechat-Roussel Pharmaceuticals, Inc. 6- and 7-deoxyforskolin and derivatives thereof
EP0447962A1 (en) * 1990-03-17 1991-09-25 Hoechst Aktiengesellschaft Labdanes and process for their preparation
IE911192A1 (en) * 1990-04-12 1991-10-23 Merck & Co Inc Substituted aromatic sulfonamides as antiglaucoma agents
JP3031498B2 (ja) * 1990-04-12 2000-04-10 メルク エンド カムパニー インコーポレーテッド 抗緑内障剤としての置換芳香族スルホンアミド類
YU128291A (sh) * 1990-07-24 1994-09-09 Joechst Aktiengesellschaft Postpak za dobijanje 6-(3-substituisanih aminopropionil) 7-deacetilforskolinskih derivata
KR102048856B1 (ko) * 2019-09-20 2019-11-26 주식회사 램프쿡 보조뚜껑을 구비하는 조리용기용 뚜껑

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4517200A (en) * 1982-12-27 1985-05-14 Schering-Plough Corporation Method for treating allergic reactions with forskolin
ATE60767T1 (de) * 1984-12-14 1991-02-15 Hoechst Roussel Pharma Aminoacyllabdane, verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung als arzneimittel.
IN163242B (fi) * 1985-05-03 1988-08-27 Hoechst India

Also Published As

Publication number Publication date
AU577928B2 (en) 1988-10-06
ES552465A0 (es) 1987-05-01
ES557152A0 (es) 1988-01-01
EP0193132A3 (en) 1987-07-29
NO860758L (fi) 1986-09-02
EP0193132B1 (en) 1991-04-17
ES8801241A1 (es) 1988-01-01
AU5423686A (en) 1986-09-04
DE3678736D1 (de) 1991-05-23
PH23778A (en) 1989-11-03
ES8801240A1 (es) 1988-01-01
ZA861505B (en) 1987-06-24
ES557151A0 (es) 1987-08-16
DK92786A (da) 1986-09-02
KR910007967B1 (ko) 1991-10-04
JPS61210081A (ja) 1986-09-18
ES8707724A1 (es) 1987-08-16
EP0193132A2 (en) 1986-09-03
ATE62683T1 (de) 1991-05-15
PT82097A (en) 1986-03-01
DK92786D0 (da) 1986-02-28
ES8705414A1 (es) 1987-05-01
ES557153A0 (es) 1988-01-01
PT82097B (pt) 1988-07-01
KR860007277A (ko) 1986-10-10
HUT42080A (en) 1987-06-29
FI860842A0 (fi) 1986-02-27
GR860571B (en) 1986-06-18

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FD Application lapsed

Owner name: HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED