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FI853763L - 1,3-dimetyl-1h-purin-2,6-dioner, som innehaoller 1h-indol-3-yl. - Google Patents

1,3-dimetyl-1h-purin-2,6-dioner, som innehaoller 1h-indol-3-yl.

Info

Publication number
FI853763L
FI853763L FI853763A FI853763A FI853763L FI 853763 L FI853763 L FI 853763L FI 853763 A FI853763 A FI 853763A FI 853763 A FI853763 A FI 853763A FI 853763 L FI853763 L FI 853763L
Authority
FI
Finland
Prior art keywords
indol
dimethyl
dioner
purin
compounds
Prior art date
Application number
FI853763A
Other languages
English (en)
Other versions
FI853763A0 (fi
FI83220C (fi
FI83220B (fi
Inventor
Ludo Edmond Josephine Kennis
Jan Vandenberk
Jozef Martin Boey
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of FI853763A0 publication Critical patent/FI853763A0/fi
Publication of FI853763L publication Critical patent/FI853763L/fi
Application granted granted Critical
Publication of FI83220B publication Critical patent/FI83220B/fi
Publication of FI83220C publication Critical patent/FI83220C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
FI853763A 1984-10-01 1985-09-30 Foerfarande foer framstaellning av terapeutiskt anvaendbara 1,3-dimetyl-1h-purin-2,6-dionderivat. FI83220C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/656,561 US4548939A (en) 1984-10-01 1984-10-01 1H-Indol-3-yl containing 1,3-dimethyl-1H-purine-2,6-diones
US65656184 1984-10-01

Publications (4)

Publication Number Publication Date
FI853763A0 FI853763A0 (fi) 1985-09-30
FI853763L true FI853763L (fi) 1986-04-02
FI83220B FI83220B (fi) 1991-02-28
FI83220C FI83220C (fi) 1991-06-10

Family

ID=24633577

Family Applications (1)

Application Number Title Priority Date Filing Date
FI853763A FI83220C (fi) 1984-10-01 1985-09-30 Foerfarande foer framstaellning av terapeutiskt anvaendbara 1,3-dimetyl-1h-purin-2,6-dionderivat.

Country Status (17)

Country Link
US (1) US4548939A (fi)
EP (1) EP0177087B1 (fi)
JP (1) JPH0653742B2 (fi)
CN (1) CN1011311B (fi)
AT (1) ATE60604T1 (fi)
AU (1) AU576386B2 (fi)
CA (1) CA1262348A (fi)
DE (1) DE3581577D1 (fi)
DK (1) DK163996C (fi)
ES (1) ES8609324A1 (fi)
FI (1) FI83220C (fi)
GR (1) GR852375B (fi)
IE (1) IE58747B1 (fi)
NO (1) NO162069C (fi)
NZ (1) NZ213498A (fi)
PT (1) PT81229B (fi)
ZA (1) ZA857553B (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH648559A5 (de) * 1981-07-20 1985-03-29 Siegfried Ag Theophyllinderivate und verfahren zu deren herstellung.
US4742057A (en) * 1985-12-05 1988-05-03 Fujisawa Pharmaceutical Co., Ltd. Antiallergic thiazole compounds
GB8719167D0 (en) * 1987-08-13 1987-09-23 Glaxo Group Ltd Chemical compounds
PH24976A (en) * 1987-08-13 1990-12-26 Glaxo Group Ltd Indole derivatives
DK733788A (da) * 1988-01-14 1989-07-15 Fujisawa Pharmaceutical Co Indolylpiperidinderivater og fremgangsmaade til fremstilling deraf
GB8819024D0 (en) * 1988-08-10 1988-09-14 Glaxo Group Ltd Chemical compounds
DE8817122U1 (de) * 1988-12-22 1993-02-04 Boehringer Ingelheim Kg, 55218 Ingelheim Neue Xanthinderivate mit Adenosinantogenistischer Wirkung
DK292A (da) * 1991-11-29 1992-01-02 Tanisake Kk Middel
DE4414113A1 (de) * 1994-04-22 1995-10-26 Merck Patent Gmbh 3-Indolylpiperidine
CN101801362B (zh) * 2007-06-22 2014-01-22 海德拉生物科学公司 用于治疗病症的方法和组合物
WO2009140517A1 (en) 2008-05-14 2009-11-19 Hydra Biosciences, Inc. Compounds and compositions for treating chemical warfare agent-induced injuries
WO2010039289A2 (en) 2008-05-14 2010-04-08 Hydra Biosciences, Inc. Compounds and compositions for treating chemical warfare agent-induced injuries

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2322470A1 (de) * 1973-05-04 1974-11-21 Boehringer Sohn Ingelheim Neue indolyl-piperidino-(bzw. 1,2,5,6tetrahydro-pyridyl-)butyrophenone und verfahren zu ihrer herstellung
FR2334358A1 (fr) * 1975-12-12 1977-07-08 Sogeras Nouveaux medicaments derives de l'indole
FR2362628A1 (fr) * 1976-08-26 1978-03-24 Roussel Uclaf Nouveaux derives du piperidyl-indole et leurs sels, procede de preparation et application a titre de medicaments
EP0011399A1 (en) * 1978-11-11 1980-05-28 FISONS plc N-substituted theophyllines, processes for their preparation and pharmaceutical compositions containing them
DE2922159A1 (de) * 1979-05-31 1980-12-04 Boehringer Mannheim Gmbh Neue xanthin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4342870A (en) * 1980-03-28 1982-08-03 Janssen Pharmaceutica N.V. Novel 3-(1-piperidinylalkyl)-4H-pyrido[1,2-a]pyrimidin-4-one derivatives
US4426383A (en) * 1980-09-04 1984-01-17 Eisai Co., Ltd. Theophylline and theobromine derivatives
US4359468A (en) * 1981-02-25 1982-11-16 Boehringer Ingelheim Ltd. Antiallergic N-[4-(indolyl)-piperidino-alkyl]-benzimidazolones
US4443451A (en) * 1981-07-15 1984-04-17 Janssen Pharmaceutica N.V. Bicyclic pyrimidin-5-one derivatives
CH648559A5 (de) * 1981-07-20 1985-03-29 Siegfried Ag Theophyllinderivate und verfahren zu deren herstellung.

Also Published As

Publication number Publication date
DK444085A (da) 1986-04-02
PT81229B (pt) 1987-11-30
AU4812485A (en) 1986-04-10
IE852403L (en) 1986-04-01
DK444085D0 (da) 1985-09-30
GR852375B (fi) 1986-01-31
AU576386B2 (en) 1988-08-25
ZA857553B (en) 1987-05-27
NO162069B (no) 1989-07-24
NO853856L (no) 1986-04-02
EP0177087A3 (en) 1986-06-11
DK163996B (da) 1992-04-27
FI853763A0 (fi) 1985-09-30
JPS6187681A (ja) 1986-05-06
ATE60604T1 (de) 1991-02-15
ES8609324A1 (es) 1986-07-16
FI83220C (fi) 1991-06-10
NZ213498A (en) 1988-04-29
EP0177087B1 (en) 1991-01-30
DE3581577D1 (de) 1991-03-07
DK163996C (da) 1992-09-21
JPH0653742B2 (ja) 1994-07-20
CN85105804A (zh) 1986-10-22
IE58747B1 (en) 1993-11-03
NO162069C (no) 1989-11-01
PT81229A (en) 1985-11-01
CN1011311B (zh) 1991-01-23
FI83220B (fi) 1991-02-28
ES547447A0 (es) 1986-07-16
US4548939A (en) 1985-10-22
EP0177087A2 (en) 1986-04-09
CA1262348A (en) 1989-10-17

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Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: JANSSEN PHARMACEUTICA N.V.