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FI822632L - Nya kefemfoerbindningar och metoder foer deras framstaellning - Google Patents

Nya kefemfoerbindningar och metoder foer deras framstaellning

Info

Publication number
FI822632L
FI822632L FI822632A FI822632A FI822632L FI 822632 L FI822632 L FI 822632L FI 822632 A FI822632 A FI 822632A FI 822632 A FI822632 A FI 822632A FI 822632 L FI822632 L FI 822632L
Authority
FI
Finland
Prior art keywords
framework
new methods
new
methods
Prior art date
Application number
FI822632A
Other languages
English (en)
Other versions
FI73688C (fi
FI822632A0 (fi
FI73688B (fi
Inventor
Takao Takaya
Hisashi Takasugi
Hideaki Yamanaka
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of FI822632A0 publication Critical patent/FI822632A0/fi
Publication of FI822632L publication Critical patent/FI822632L/fi
Application granted granted Critical
Publication of FI73688B publication Critical patent/FI73688B/fi
Publication of FI73688C publication Critical patent/FI73688C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI822632A 1981-08-03 1982-07-28 Foerfarande foer framstaellning av farmakologiskt verksamma 7-/2-(4-tiazolyl)-2-oxiimino-acetamido/-3- cefem-4-karboxylsyraderivats syn-isomerer. FI73688C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8123683 1981-08-03
GB8123683 1981-08-03
GB8131261 1981-10-16
GB8131261 1981-10-16

Publications (4)

Publication Number Publication Date
FI822632A0 FI822632A0 (fi) 1982-07-28
FI822632L true FI822632L (fi) 1983-02-04
FI73688B FI73688B (fi) 1987-07-31
FI73688C FI73688C (fi) 1987-11-09

Family

ID=26280336

Family Applications (1)

Application Number Title Priority Date Filing Date
FI822632A FI73688C (fi) 1981-08-03 1982-07-28 Foerfarande foer framstaellning av farmakologiskt verksamma 7-/2-(4-tiazolyl)-2-oxiimino-acetamido/-3- cefem-4-karboxylsyraderivats syn-isomerer.

Country Status (15)

Country Link
US (3) US4515788A (fi)
EP (1) EP0071891B1 (fi)
KR (1) KR880001411B1 (fi)
AU (1) AU556624B2 (fi)
CA (1) CA1209125A (fi)
DE (1) DE3274548D1 (fi)
DK (1) DK335882A (fi)
ES (2) ES514652A0 (fi)
FI (1) FI73688C (fi)
GR (1) GR76166B (fi)
HU (1) HU188586B (fi)
IE (1) IE53429B1 (fi)
NO (1) NO160079C (fi)
PT (1) PT75349B (fi)
SU (1) SU1155159A3 (fi)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE53429B1 (en) * 1981-08-03 1988-11-09 Fujisawa Pharmaceutical Co New cephem compounds and processes for preparation thereof
US4708955A (en) * 1985-06-24 1987-11-24 Bristol-Myers Company 3-(substituted)propenyl-7-aminothiazol-ylcephalosporanic acids and esters thereof
US4874856A (en) * 1985-06-24 1989-10-17 Bristol-Myers Company 3-(substituted)propenyl-7-(aminothiazolylacetamido) ceph-3-em-4-carboxylic acids and esters thereof
US4731362A (en) * 1985-08-05 1988-03-15 Shionogi & Co., Ltd. Alkylcarbamoyloxymethylcephem compounds
US20130065874A1 (en) 2011-09-09 2013-03-14 Cubist Pharmaceuticals, Inc. Methods for treating intrapulmonary infections
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
US20140274996A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Tazobactam and ceftolozane antibiotic compositions
MX2020004205A (es) 2013-03-15 2021-11-16 Merck Sharp & Dohme Llc Composiciones antibioticas de ceftolozano.
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
EP3043797B1 (en) 2013-09-09 2020-04-08 Merck Sharp & Dohme Corp. Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
US8906898B1 (en) 2013-09-27 2014-12-09 Calixa Therapeutics, Inc. Solid forms of ceftolozane
KR102192524B1 (ko) * 2019-06-28 2020-12-17 에스케이씨 주식회사 폴리비닐아세탈 수지 조성물의 제조방법, 폴리비닐아세탈 수지 조성물 및 이를 포함하는 접합용 필름

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3971778A (en) * 1972-05-12 1976-07-27 Glaxo Laboratories Limited Cephalosporins having (α-etherified oximino)acylamido groups at the 7-position
US4364943A (en) * 1976-04-12 1982-12-21 Fujisawa Pharmaceutical Co., Ltd. Syn-isomer of 7-[2-alkoxyimino-2-(2-amino-alkanoylamino-or haloalkanoylamino-thiazol-4-yl) acetamids]-3-[hexanoyl-, or phenylalkanoyl-oxymethyl or benzothiazolylthiomethyl]-3-cephem-4-carboxylic acid
GB1592149A (en) * 1976-10-08 1981-07-01 Fujisawa Pharmaceutical Co 3 7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for preparation thereof
SE439312B (sv) * 1977-03-25 1985-06-10 Roussel Uclaf Sett att framstella nya oximderivat av 3-acetoximetyl-7-aminotiazolylacetamido cefalosporansyra
FR2421907A1 (fr) * 1978-04-07 1979-11-02 Roussel Uclaf Nouvelles cephalosporines derivees de l'acide 7-/2-(2-amino 4-thiazolyl)2-(carboxymethoxyimino/acetamido 3-substitue cephalosporanique, leur procede de preparation et leur application comme medicaments
DE2822860A1 (de) * 1978-05-26 1979-11-29 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
FR2445830A1 (fr) * 1979-01-05 1980-08-01 Roussel Uclaf Nouveaux derives de l'acide (4-thiazolyl) acetique procede de preparation
JPS55133385A (en) * 1979-04-03 1980-10-17 Fujisawa Pharmaceut Co Ltd Novel cephem compound, its preparation, and remedy and preventive against microbism
DE2914327A1 (de) * 1979-04-09 1980-10-30 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
US4409215A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical Co., Ltd. 7-Acylamino-3-substituted cephalosporanic acid derivatives and processes for the preparation thereof
US4409214A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
US4572801A (en) * 1981-04-30 1986-02-25 Takeda Chemical Industries, Ltd. 4-Carbamoyloxymethyl-1-sulfo-2-oxoazetidine derivatives and their production
IE53429B1 (en) * 1981-08-03 1988-11-09 Fujisawa Pharmaceutical Co New cephem compounds and processes for preparation thereof
US4499088A (en) * 1983-01-04 1985-02-12 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds

Also Published As

Publication number Publication date
ES8308569A1 (es) 1983-08-16
FI73688C (fi) 1987-11-09
FI822632A0 (fi) 1982-07-28
EP0071891B1 (en) 1986-12-03
US4515788A (en) 1985-05-07
FI73688B (fi) 1987-07-31
EP0071891A2 (en) 1983-02-16
ES514652A0 (es) 1983-08-16
EP0071891A3 (en) 1984-05-16
GR76166B (fi) 1984-08-03
US4649136A (en) 1987-03-10
KR880001411B1 (ko) 1988-08-01
ES521047A0 (es) 1985-05-01
SU1155159A3 (ru) 1985-05-07
PT75349A (en) 1982-08-01
DE3274548D1 (en) 1987-01-15
AU8642382A (en) 1983-02-24
NO160079B (no) 1988-11-28
AU556624B2 (en) 1986-11-13
CA1209125A (en) 1986-08-05
KR840000565A (ko) 1984-02-25
DK335882A (da) 1983-02-04
HU188586B (en) 1986-04-28
IE821772L (en) 1983-02-03
IE53429B1 (en) 1988-11-09
NO822634L (no) 1983-02-04
NO160079C (no) 1989-03-08
US4736039A (en) 1988-04-05
ES8504817A1 (es) 1985-05-01
PT75349B (en) 1984-07-31

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: FUJISAWA PHARMACEUTICAL CO., LTD