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FI20011507A0 - Uusia yhdisteitä - Google Patents

Uusia yhdisteitä

Info

Publication number
FI20011507A0
FI20011507A0 FI20011507A FI20011507A FI20011507A0 FI 20011507 A0 FI20011507 A0 FI 20011507A0 FI 20011507 A FI20011507 A FI 20011507A FI 20011507 A FI20011507 A FI 20011507A FI 20011507 A0 FI20011507 A0 FI 20011507A0
Authority
FI
Finland
Prior art keywords
new compounds
compounds
new
Prior art date
Application number
FI20011507A
Other languages
English (en)
Swedish (sv)
Inventor
Tuula Koskelainen
Leena Otsomaa
Arto Karjalainen
Pekka Kotovuori
Jukka Tenhunen
Original Assignee
Orion Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Corp filed Critical Orion Corp
Priority to FI20011507A priority Critical patent/FI20011507A0/fi
Publication of FI20011507A0 publication Critical patent/FI20011507A0/fi
Priority to MXPA04000267A priority patent/MXPA04000267A/es
Priority to HU0400391A priority patent/HUP0400391A3/hu
Priority to PCT/FI2002/000621 priority patent/WO2003006452A1/en
Priority to KR10-2004-7000332A priority patent/KR20040025697A/ko
Priority to SI200230422T priority patent/SI1412343T1/sl
Priority to CA2452918A priority patent/CA2452918C/en
Priority to YUP-6/04A priority patent/RS50886B/sr
Priority to CNB028138635A priority patent/CN1281597C/zh
Priority to DK02755036T priority patent/DK1412343T3/da
Priority to EA200400161A priority patent/EA006580B1/ru
Priority to AU2002321339A priority patent/AU2002321339B2/en
Priority to ES02755036T priority patent/ES2269746T3/es
Priority to AT02755036T priority patent/ATE338038T1/de
Priority to PT02755036T priority patent/PT1412343E/pt
Priority to NZ530490A priority patent/NZ530490A/en
Priority to EP02755036A priority patent/EP1412343B1/en
Priority to ARP020102586A priority patent/AR036236A1/es
Priority to IL15964702A priority patent/IL159647A0/xx
Priority to US10/482,396 priority patent/US7425568B2/en
Priority to PL02367958A priority patent/PL367958A1/xx
Priority to BR0211070-9A priority patent/BR0211070A/pt
Priority to DE60214388T priority patent/DE60214388T2/de
Priority to JP2003512224A priority patent/JP4113839B2/ja
Priority to UA2004020928A priority patent/UA76168C2/uk
Priority to NO20035821A priority patent/NO20035821L/no
Priority to IL159647A priority patent/IL159647A/en
Priority to ZA200400145A priority patent/ZA200400145B/en
Priority to HR20040133A priority patent/HRP20040133A2/hr
Priority to HK05100708A priority patent/HK1068611A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/78—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C217/80—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings
    • C07C217/82—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring
    • C07C217/90—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring the oxygen atom of at least one of the etherified hydroxy groups being further bound to a carbon atom of a six-membered aromatic ring, e.g. amino-diphenylethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D411/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Pyrane Compounds (AREA)
FI20011507A 2001-07-10 2001-07-10 Uusia yhdisteitä FI20011507A0 (fi)

Priority Applications (30)

Application Number Priority Date Filing Date Title
FI20011507A FI20011507A0 (fi) 2001-07-10 2001-07-10 Uusia yhdisteitä
JP2003512224A JP4113839B2 (ja) 2001-07-10 2002-07-10 Ｎａ＋／Ｃａ２＋交換機構の強力な阻害剤であり、不整脈の処置において有用である新規化合物
PT02755036T PT1412343E (pt) 2001-07-10 2002-07-10 Compostos que são potentes inibidores do mecanismo de permuta na+/ca2+ e úteis no tratamento de arritmias
EP02755036A EP1412343B1 (en) 2001-07-10 2002-07-10 Compounds, which are potent inhibitors of na+/ca2+ exchange mechanism and are useful in the treatment of arrhythmias
NZ530490A NZ530490A (en) 2001-07-10 2002-07-10 New compounds, which are potent inhibitors of Na+/Ca2+ exchange mechanism and are useful in the treatment of arrhythmias
KR10-2004-7000332A KR20040025697A (ko) 2001-07-10 2002-07-10 소디움 이온/칼슘 이온 교환 메카니즘의 강력한저해제이며, 부정맥 치료에 유용한 신규 화합물
HU0400391A HUP0400391A3 (en) 2001-07-10 2002-07-10 New compounds, which are potent inhibitors of na+/ca2+ exchange and pharmaceutical compositions containing them
CA2452918A CA2452918C (en) 2001-07-10 2002-07-10 New compounds, which are potent inhibitors of na+/ca2+ exchange mechanism and are useful in the treatment of arrhythmias
YUP-6/04A RS50886B (sr) 2001-07-10 2002-07-10 Nova jedinjenja koja su jaki inhibitori mehanizma za izmenu na+/ca2+ i korisni su kod lečenja aritmija
CNB028138635A CN1281597C (zh) 2001-07-10 2002-07-10 可用作Na+/Ca2+交换机制的有效抑制剂并可用于治疗心律失常的新化合物
DK02755036T DK1412343T3 (da) 2001-07-10 2002-07-10 Forbindelser, som er stærke inhibitorer af Na+/Ca2+udbytningsmekanismen og er nyttige til behandling af arytmier
EA200400161A EA006580B1 (ru) 2001-07-10 2002-07-10 Новые соединения, являющиеся сильнодействующими ингибиторами механизма обмена ионов na+/ca2+ при лечении аритмии
AU2002321339A AU2002321339B2 (en) 2001-07-10 2002-07-10 New compounds, which are potent inhibitors of NA+/CA2+ exchange mechanism and are useful in the treatment of arrhythmias
ARP020102586A AR036236A1 (es) 2001-07-10 2002-07-10 Inhibidores del mecanismo de intercambio na+/ca2+ y metodo para la inhibicion del mecanismo de intercambio na+/ca2+ en celulas y para el tratamiento de arritmias
AT02755036T ATE338038T1 (de) 2001-07-10 2002-07-10 Verbindungen, bei denen es sich um wirksame inhibitoren des na+/ca2+ austauschmechanismus handelt und die sich zur behandlung von arrhythmien eignen
MXPA04000267A MXPA04000267A (es) 2001-07-10 2002-07-10 Compuestos novedosos, los cuales son inhibidores potentes del mecanismo de intercambio de na+/ca2+ y son utiles en el tratamiento de arritmias.
PCT/FI2002/000621 WO2003006452A1 (en) 2001-07-10 2002-07-10 New compounds, which are potent inhibitors of na+/ca2+ exchange mechanism and are useful in the treatment of arrhythmias
SI200230422T SI1412343T1 (sl) 2001-07-10 2002-07-10 Spojine, ki so ucinkoviti inhibitorji mehanizma izmenjave Na+/Ca2+ in so uporabne pri zdravljenju aritmij
ES02755036T ES2269746T3 (es) 2001-07-10 2002-07-10 Compuestos, que son potentes inhibidores del mecanismo de intercambio na+/ca2+ y que son utiles en el tratamiento de arritmias.
IL15964702A IL159647A0 (en) 2001-07-10 2002-07-10 NEW COMPOUNDS, WHICH ARE POTENT INHIBITORS OF Na+/Ca2+ EXCHANGE MECHANISM AND ARE USEFUL IN THE TREATMENT OF ARRHYTHMIAS
US10/482,396 US7425568B2 (en) 2001-07-10 2002-07-10 Compounds, which are potent inhibitors of Na+ /Ca2+ exchange mechanism and are useful in the treatment of arrhythmias
PL02367958A PL367958A1 (en) 2001-07-10 2002-07-10 New compounds, which are potent inhibitors of na+/ca2+ exchange mechanism and are useful in the treatment of arrhythmias
BR0211070-9A BR0211070A (pt) 2001-07-10 2002-07-10 Compostos inovadores que são inibidores potentes do mecanismo de troca na+/ca2+ e são úteis no tratamento de arritmias
DE60214388T DE60214388T2 (de) 2001-07-10 2002-07-10 Verbindungen, bei denen es sich um wirksame inhibitoren des na+/ca2+ austauschmechanismus handelt und die sich zur behandlung von arrhythmien eignen
UA2004020928A UA76168C2 (en) 2001-07-10 2002-10-07 COMPOUNDS BEING DRASTIC INHIBITORS OF Na+/Ca+2 EXCHANGE MECHANISM IN TREATMENT OF ARRHYTHMIA
NO20035821A NO20035821L (no) 2001-07-10 2003-12-23 Nye forbindelser som er kraftige inhibitoer av Na<O>+</O>/Ca<O>+</O> utvekslingsmekanismer og som nyttige i behandlingen av arrytmier
IL159647A IL159647A (en) 2001-07-10 2003-12-30 Compounds that suppress the activity of mechanase + NA + / CA² replacement and are useful in the treatment of disorders
ZA200400145A ZA200400145B (en) 2001-07-10 2004-01-08 New compounds, which are potent inhibitors of Na<+>/Ca<2+> exchange mechanism and are useful in the treatment of arrhythmias.
HR20040133A HRP20040133A2 (en) 2001-07-10 2004-02-09 NEW COMPOUNDS, WHICH ARE POTENT INHIBITORS OF Na+/Ca2+ EXCHANGE MECHANISM AND ARE USEFUL IN THE TREATMENT OF ARRHYTHMIAS
HK05100708A HK1068611A1 (en) 2001-07-10 2005-01-27 New compounds, which are potent inhibitors of na+/ca2+ exchange mechanism and are useful in the treatment of arrhythmias

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI20011507A FI20011507A0 (fi) 2001-07-10 2001-07-10 Uusia yhdisteitä

Publications (1)

Publication Number Publication Date
FI20011507A0 true FI20011507A0 (fi) 2001-07-10

Family

ID=8561628

Family Applications (1)

Application Number Title Priority Date Filing Date
FI20011507A FI20011507A0 (fi) 2001-07-10 2001-07-10 Uusia yhdisteitä

Country Status (28)

Country Link
US (1) US7425568B2 (fi)
EP (1) EP1412343B1 (fi)
JP (1) JP4113839B2 (fi)
KR (1) KR20040025697A (fi)
CN (1) CN1281597C (fi)
AR (1) AR036236A1 (fi)
AT (1) ATE338038T1 (fi)
AU (1) AU2002321339B2 (fi)
BR (1) BR0211070A (fi)
CA (1) CA2452918C (fi)
DE (1) DE60214388T2 (fi)
DK (1) DK1412343T3 (fi)
EA (1) EA006580B1 (fi)
ES (1) ES2269746T3 (fi)
FI (1) FI20011507A0 (fi)
HK (1) HK1068611A1 (fi)
HR (1) HRP20040133A2 (fi)
HU (1) HUP0400391A3 (fi)
IL (2) IL159647A0 (fi)
MX (1) MXPA04000267A (fi)
NO (1) NO20035821L (fi)
NZ (1) NZ530490A (fi)
PL (1) PL367958A1 (fi)
PT (1) PT1412343E (fi)
RS (1) RS50886B (fi)
UA (1) UA76168C2 (fi)
WO (1) WO2003006452A1 (fi)
ZA (1) ZA200400145B (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI20030030A0 (fi) * 2003-01-09 2003-01-09 Orion Corp Uusia yhdisteitä
CN101137639B (zh) 2005-03-11 2012-05-23 霍华德弗洛里生理医学实验研究所 类黄酮化合物及其用途
US8912224B2 (en) 2011-09-12 2014-12-16 Sanofi Substituted 2-(chroman-6-yloxy)-thiazoles and their use as pharmaceuticals
JP5941637B2 (ja) * 2011-09-12 2016-06-29 サノフイ 置換２−（クロマン−６−イルオキシ）−チアゾール及び医薬としてのその使用
RS53748B1 (en) * 2011-09-12 2015-06-30 Sanofi 2- (CHROMAN-6-ILOXY) -THIAZOLES AND THEIR USE AS PHARMACEUTICAL PRODUCTS
CA2846347C (en) * 2011-09-12 2019-05-21 Sanofi Substituted 2-(chroman-6-yloxy)-thiazoles and their use as pharmaceuticals
CN102993195B (zh) * 2011-09-14 2017-05-17 赛诺菲 取代的2‑(色满‑6‑基氧基)噻唑及其作为药物的用途
CN103030646B (zh) * 2011-09-29 2016-08-24 上海恒瑞医药有限公司 苯并二氧六环类衍生物、其制备方法及其在医药上的应用
TWI633095B (zh) * 2013-03-08 2018-08-21 賽諾菲公司 經取代－６－基氧基－環烷類及其作為醫藥品之用途
GB201416186D0 (en) 2014-09-12 2014-10-29 Redx Pharma Ltd Compounds
WO2019175464A1 (en) 2018-03-14 2019-09-19 Orion Corporation Compounds useful as inhibitors of sodium-calcium exchanger (ncx)
MX2023001275A (es) 2020-07-28 2023-04-24 Jazz Pharmaceuticals Ireland Ltd Inhibidores de raf biciclicos fusionados y metodos para su uso.

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GB1154119A (en) 1968-05-20 1969-06-04 Merck Ag E 3-Alkyl-Flavanones
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RS604A (en) 2006-12-15
PL367958A1 (en) 2005-03-07
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EA006580B1 (ru) 2006-02-24
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RS50886B (sr) 2010-08-31
BR0211070A (pt) 2004-06-15
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CA2452918A1 (en) 2003-01-23
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