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FI103381B1 - Hyaluronihapon veteen liukenemattomia geelejä ja menetelmä sen valmistamiseksi - Google Patents

Hyaluronihapon veteen liukenemattomia geelejä ja menetelmä sen valmistamiseksi

Info

Publication number
FI103381B1
FI103381B1 FI925802A FI925802A FI103381B1 FI 103381 B1 FI103381 B1 FI 103381B1 FI 925802 A FI925802 A FI 925802A FI 925802 A FI925802 A FI 925802A FI 103381 B1 FI103381 B1 FI 103381B1
Authority
FI
Finland
Prior art keywords
hyaluronic acid
insoluble
preparation
water
acid gels
Prior art date
Application number
FI925802A
Other languages
English (en)
Swedish (sv)
Other versions
FI925802A (fi
FI103381B (fi
FI925802A0 (fi
Inventor
James W Burns
Steven Cox
Alan E Walts
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of FI925802A publication Critical patent/FI925802A/fi
Publication of FI925802A0 publication Critical patent/FI925802A0/fi
Application granted granted Critical
Publication of FI103381B publication Critical patent/FI103381B/fi
Publication of FI103381B1 publication Critical patent/FI103381B1/fi

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • A61L31/041Mixtures of macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • A61L31/042Polysaccharides
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
  • Saccharide Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI925802A 1990-06-25 1992-12-21 Hyaluronihapon veteen liukenemattomia geelejä ja menetelmä sen valmistamiseksi FI103381B1 (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US54316390 1990-06-25
US07/543,163 US5017229A (en) 1990-06-25 1990-06-25 Water insoluble derivatives of hyaluronic acid
US9104543 1991-06-25
PCT/US1991/004543 WO1992000105A1 (en) 1990-06-25 1991-06-25 Water insoluble derivatives of hyaluronic acid

Publications (4)

Publication Number Publication Date
FI925802A FI925802A (fi) 1992-12-21
FI925802A0 FI925802A0 (fi) 1992-12-21
FI103381B FI103381B (fi) 1999-06-30
FI103381B1 true FI103381B1 (fi) 1999-06-30

Family

ID=24166845

Family Applications (1)

Application Number Title Priority Date Filing Date
FI925802A FI103381B1 (fi) 1990-06-25 1992-12-21 Hyaluronihapon veteen liukenemattomia geelejä ja menetelmä sen valmistamiseksi

Country Status (12)

Country Link
US (1) US5017229A (fi)
EP (1) EP0537292B1 (fi)
JP (1) JP3399526B2 (fi)
AT (1) ATE151294T1 (fi)
AU (1) AU660282B2 (fi)
DE (1) DE69125609T2 (fi)
DK (1) DK0537292T3 (fi)
ES (1) ES2100954T3 (fi)
FI (1) FI103381B1 (fi)
GR (1) GR3023436T3 (fi)
NO (1) NO306380B1 (fi)
WO (1) WO1992000105A1 (fi)

Families Citing this family (213)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5527893A (en) * 1987-09-18 1996-06-18 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
US6030958A (en) * 1987-09-18 2000-02-29 Genzyme Corporation Water insoluble derivatives of hyaluronic acid
US6174999B1 (en) * 1987-09-18 2001-01-16 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
US6610669B1 (en) * 1987-09-18 2003-08-26 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
US6235726B1 (en) * 1987-09-18 2001-05-22 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
IT1219587B (it) * 1988-05-13 1990-05-18 Fidia Farmaceutici Polisaccaridi carbossiilici autoreticolati
US5510418A (en) * 1988-11-21 1996-04-23 Collagen Corporation Glycosaminoglycan-synthetic polymer conjugates
US5356883A (en) 1989-08-01 1994-10-18 Research Foundation Of State University Of N.Y. Water-insoluble derivatives of hyaluronic acid and their methods of preparation and use
US5234914A (en) * 1991-06-11 1993-08-10 Patent Biopharmaceutics, Inc. Methods of treating hemorrhoids and anorecial disease
AU636544B1 (en) * 1991-11-27 1993-04-29 Lignyte Co., Ltd. Water insoluble biocompatible hyaluronic acid polyion complex and method of making the same
CA2072918A1 (en) * 1992-02-14 1993-08-15 Jian Qin Modified polysaccharides having improved absorbent properties and process for the preparation thereof
WO1994021299A1 (en) * 1993-03-19 1994-09-29 Medinvent A composition and a method for tissue augmentation
US5616568A (en) * 1993-11-30 1997-04-01 The Research Foundation Of State University Of New York Functionalized derivatives of hyaluronic acid
ITPD940054A1 (it) * 1994-03-23 1995-09-23 Fidia Advanced Biopolymers Srl Polisaccaridi solfatati
US5585361A (en) 1994-06-07 1996-12-17 Genzyme Corporation Methods for the inhibition of platelet adherence and aggregation
US5931165A (en) * 1994-09-06 1999-08-03 Fusion Medical Technologies, Inc. Films having improved characteristics and methods for their preparation and use
US6294202B1 (en) 1994-10-06 2001-09-25 Genzyme Corporation Compositions containing polyanionic polysaccharides and hydrophobic bioabsorbable polymers
US6063116A (en) * 1994-10-26 2000-05-16 Medarex, Inc. Modulation of cell proliferation and wound healing
US6063396A (en) * 1994-10-26 2000-05-16 Houston Biotechnology Incorporated Methods and compositions for the modulation of cell proliferation and wound healing
US5498705A (en) * 1995-02-22 1996-03-12 Kimberly-Clark Corporation Modified polysaccharides having improved absorbent properties and process for the preparation thereof
US6262255B1 (en) * 1995-04-05 2001-07-17 Biomm, Inc. Non-immunogenic, biocompatible macromolecular membrane compositions, and methods for making them
US5827937A (en) * 1995-07-17 1998-10-27 Q Med Ab Polysaccharide gel composition
US6036977A (en) * 1995-09-29 2000-03-14 L.A.M. Pharmaceutical Corp. Drug preparations for treating sexual dysfunction
US6251436B1 (en) 1995-09-29 2001-06-26 L.A.M. Pharmaceutical Corporation Drug preparations for treating sexual dysfunction
US5952006A (en) * 1995-09-29 1999-09-14 L.A.M. Pharmaceuticals, Llc Drug preparations for treating impotency
US6387407B1 (en) 1995-09-29 2002-05-14 L.A.M. Pharmaceutical Corporation Topical drug preparations
US5716631A (en) * 1995-09-29 1998-02-10 Rdn Therapeutics Inc. Long acting narcotic analgesics and antagonists
US5897880A (en) 1995-09-29 1999-04-27 Lam Pharmaceuticals, Llc. Topical drug preparations
EP1704878B1 (en) * 1995-12-18 2013-04-10 AngioDevice International GmbH Crosslinked polymer compositions and methods for their use
US6833408B2 (en) * 1995-12-18 2004-12-21 Cohesion Technologies, Inc. Methods for tissue repair using adhesive materials
US7883693B2 (en) 1995-12-18 2011-02-08 Angiodevice International Gmbh Compositions and systems for forming crosslinked biomaterials and methods of preparation of use
US5791352A (en) * 1996-06-19 1998-08-11 Fusion Medical Technologies, Inc. Methods and compositions for inhibiting tissue adhesion
US8303981B2 (en) 1996-08-27 2012-11-06 Baxter International Inc. Fragmented polymeric compositions and methods for their use
US7435425B2 (en) * 2001-07-17 2008-10-14 Baxter International, Inc. Dry hemostatic compositions and methods for their preparation
US6066325A (en) * 1996-08-27 2000-05-23 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
US7871637B2 (en) 1996-08-27 2011-01-18 Baxter International Inc. Dry hemostatic compositions and methods for their preparation
US6063061A (en) * 1996-08-27 2000-05-16 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
US8603511B2 (en) 1996-08-27 2013-12-10 Baxter International, Inc. Fragmented polymeric compositions and methods for their use
FR2752843B1 (fr) * 1996-08-30 1998-10-16 Sod Conseils Rech Applic Copolymeres reticules a base de polymeres polycarboxyliques et leur utilisation comme support de composition pharmaceutique
US8003705B2 (en) 1996-09-23 2011-08-23 Incept Llc Biocompatible hydrogels made with small molecule precursors
DE19712708A1 (de) * 1997-03-26 1998-10-01 Thueringisches Inst Textil Getrocknete kontaminationsarme Hydrokolloide und Hydrogele
US7192984B2 (en) * 1997-06-17 2007-03-20 Fziomed, Inc. Compositions of polyacids and polyethers and methods for their use as dermal fillers
US5906997A (en) * 1997-06-17 1999-05-25 Fzio Med, Inc. Bioresorbable compositions of carboxypolysaccharide polyether intermacromolecular complexes and methods for their use in reducing surgical adhesions
US20050074495A1 (en) * 1997-06-17 2005-04-07 Fziomed, Inc. Compositions of polyacids and methods for their use in reducing adhesions
US20040096422A1 (en) * 1997-06-17 2004-05-20 Schwartz Herbert E. Compositions of polyacids and polyethers and methods for their use in reducing pain
US6869938B1 (en) 1997-06-17 2005-03-22 Fziomed, Inc. Compositions of polyacids and polyethers and methods for their use in reducing adhesions
US6229009B1 (en) 1997-08-29 2001-05-08 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) Polycarboxylic based cross-linked copolymers
US6958148B1 (en) 1998-01-20 2005-10-25 Pericor Science, Inc. Linkage of agents to body tissue using microparticles and transglutaminase
US6919076B1 (en) 1998-01-20 2005-07-19 Pericor Science, Inc. Conjugates of agents and transglutaminase substrate linking molecules
US6630457B1 (en) * 1998-09-18 2003-10-07 Orthogene Llc Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same
JP2002531217A (ja) 1998-12-04 2002-09-24 チャンドラシェカー ピー. パサック, 生体適合性架橋ポリマー
FR2790391B1 (fr) 1999-03-02 2002-11-15 Flamel Tech Sa Moyen pour la prevention des adherences post-chirurgicales,a base de peptides collagenique reticule
WO2000054762A2 (en) * 1999-03-15 2000-09-21 Trustees Of Boston University Use of cross linked polysaccharides for the inhibition of angiogenesis
US20040048021A1 (en) * 1999-03-19 2004-03-11 Wan Barbara Y. F. Surface modification of substrates
CA2366897C (en) * 1999-04-06 2009-11-17 Andrew B. Onderdonk Immunomodulatory compositions and methods of use thereof
FR2799196B1 (fr) 1999-10-04 2002-02-08 Sod Conseils Rech Applic Copolymeres reticules a base de copolymeres polycarboxyliques non reticules
US7651703B2 (en) 1999-10-15 2010-01-26 Genentech, Inc. Injection vehicle for polymer-based formulations
US7582311B1 (en) 1999-10-15 2009-09-01 Genentech, Inc. Injection vehicle for polymer-based formulations
KR20020062301A (ko) * 1999-11-09 2002-07-25 덴끼 가가꾸 고교 가부시키가이샤 수난용성화된 가용성 셀룰로오스 유도체의 용도 및 그제조방법
US20030211166A1 (en) * 2001-07-31 2003-11-13 Yamamoto Ronald K Microparticulate biomaterial composition for medical use
DE60016455T2 (de) 1999-12-17 2005-12-15 Genzyme Corp., Cambridge Chirurgische prothese
CA2397578A1 (en) 1999-12-21 2001-06-28 Ajinomoto Co., Inc. A partial ester of a nitrogenous carboxylic acid with cellulose and a process for preparing the same
US6566345B2 (en) 2000-04-28 2003-05-20 Fziomed, Inc. Polyacid/polyalkylene oxide foams and gels and methods for their delivery
US20040215231A1 (en) * 2000-02-03 2004-10-28 David Fortune Device for the closure of a surgical puncture
US6521223B1 (en) * 2000-02-14 2003-02-18 Genzyme Corporation Single phase gels for the prevention of adhesions
US6749865B2 (en) * 2000-02-15 2004-06-15 Genzyme Corporation Modification of biopolymers for improved drug delivery
JP2003531682A (ja) * 2000-04-28 2003-10-28 フジオメッド インコーポレイテッド ポリ酸及びポリアルキレンオキシドの止血性組成物、並びにその使用方法
EP1305062B1 (de) * 2000-08-02 2006-11-08 Aesculap AG & Co. KG Medizintechnisches produkt, verfahren zu seiner herstellung und bereitstellung für die chirurgie
WO2002017853A2 (en) * 2000-08-31 2002-03-07 Genzyme Biosurgery Corporation Hyaluronan-based antiadhesion compositions, their preparation and use
KR100375299B1 (ko) 2000-10-10 2003-03-10 주식회사 엘지생명과학 히알루론산의 가교결합형 아마이드 유도체와 이의 제조방법
DK1328300T3 (da) * 2000-10-23 2005-03-21 Tissuemed Ltd Selvklæbende hydratiserbar matrix til topisk terapeutisk anvendelse
US6710162B2 (en) * 2001-02-16 2004-03-23 Genzyme Corporation Method of drying a material having a cohesive phase
EP1368309B2 (en) * 2001-02-22 2014-10-01 Anika Therapeutics Inc. Thiol-modified hyaluronan
US20020172712A1 (en) * 2001-03-19 2002-11-21 Alan Drizen Antiemetic, anti-motion sustained release drug delivery system
US20030138494A1 (en) * 2001-05-15 2003-07-24 L.A.M. Pharmaceutical Corporation Drug preparations for treating sexual dysfunction
WO2003057274A2 (en) * 2001-12-28 2003-07-17 Genzyme Corporation Bioresorbable foam packing device and use thereof
US20050142208A1 (en) * 2002-05-09 2005-06-30 Won Min Yoo Pharmceutical composition for treatment of wounds conntaining blood plasma or serum
US7299805B2 (en) 2002-06-07 2007-11-27 Marctec, Llc Scaffold and method for implanting cells
IL165910A0 (en) * 2002-07-03 2006-01-15 Pericor Science Inc Compositions of hyaluronic acid and methods of use
AU2003264498A1 (en) * 2002-09-18 2004-04-08 Wakamoto Pharmaceutical Co., Ltd. Transparent and reversibly heat-gelling aqueous compositions
US8673333B2 (en) * 2002-09-25 2014-03-18 The Johns Hopkins University Cross-linked polymer matrices, and methods of making and using same
US7862831B2 (en) * 2002-10-09 2011-01-04 Synthasome, Inc. Method and material for enhanced tissue-biomaterial integration
US20050069572A1 (en) * 2002-10-09 2005-03-31 Jennifer Elisseeff Multi-layered polymerizing hydrogels for tissue regeneration
TWI251596B (en) * 2002-12-31 2006-03-21 Ind Tech Res Inst Method for producing a double-crosslinked hyaluronate material
US7186725B2 (en) 2003-01-03 2007-03-06 Genzyme Corporation Anti-inflammatory compositions and methods
US6982298B2 (en) * 2003-01-10 2006-01-03 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US8138265B2 (en) * 2003-01-10 2012-03-20 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US8137688B2 (en) * 2003-01-10 2012-03-20 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US7465766B2 (en) * 2004-01-08 2008-12-16 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
JP2006523113A (ja) * 2003-04-04 2006-10-12 ティシュームド リミテッド 組織接着構成物
FR2861734B1 (fr) 2003-04-10 2006-04-14 Corneal Ind Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus
US8834864B2 (en) * 2003-06-05 2014-09-16 Baxter International Inc. Methods for repairing and regenerating human dura mater
US20070020314A1 (en) * 2003-06-30 2007-01-25 Hirotaka Haro Adhesion inhibiting material for vertebral/spinal operation
DE602004023516D1 (de) 2003-08-07 2009-11-19 Allergan Inc Zusammensetzungen zur abgabe von therapeutika in die augen und verfahren zu ihrer herstellung und verwendung
US7927626B2 (en) * 2003-08-07 2011-04-19 Ethicon, Inc. Process of making flowable hemostatic compositions and devices containing such compositions
US7625581B2 (en) * 2003-12-19 2009-12-01 Ethicon, Inc. Tissue scaffolds for use in muscoloskeletal repairs
US7091191B2 (en) * 2003-12-19 2006-08-15 Ethicon, Inc. Modified hyaluronic acid for use in musculoskeletal tissue repair
JP2005261608A (ja) * 2004-03-18 2005-09-29 Masato Kusunoki 薬物を担持した生体吸収性ゲル、パウダーおよびフィルム
US8323675B2 (en) 2004-04-20 2012-12-04 Genzyme Corporation Soft tissue prosthesis for repairing a defect of an abdominal wall or a pelvic cavity wall
BRPI0510477B1 (pt) 2004-04-28 2023-01-17 Angiotech Biomaterials Corporation Método para formar um gel e dispositivo para uso em aplicações médicas
EP1595528A1 (de) * 2004-05-14 2005-11-16 Fibona Health Products GmbH Hyaferm-Komposite
BRPI0514106A (pt) * 2004-08-03 2008-05-27 Tissuemed Ltd materiais adesivos a tecidos
US7858107B2 (en) * 2004-09-10 2010-12-28 Medtronic Xomed, Inc. Flexible bioresorbable hemostatic packing and stent having a preselectable in-vivo residence time
WO2006034128A2 (en) 2004-09-17 2006-03-30 Angiotech Biomaterials Corporation Multifunctional compounds for forming crosslinked biomaterials and methods of preparation and use
US20060069063A1 (en) * 2004-09-27 2006-03-30 Yng-Jiin Wang Crosslinked polygalacturonic acid used for postsurgical tissue adhesion prevention
US8001922B2 (en) 2004-09-28 2011-08-23 Atrium Medical Corporation Application of a coating on a medical device
US8367099B2 (en) 2004-09-28 2013-02-05 Atrium Medical Corporation Perforated fatty acid films
US8312836B2 (en) * 2004-09-28 2012-11-20 Atrium Medical Corporation Method and apparatus for application of a fresh coating on a medical device
US9012506B2 (en) 2004-09-28 2015-04-21 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
US9000040B2 (en) 2004-09-28 2015-04-07 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
EP1811933B1 (en) * 2004-09-28 2016-03-23 Atrium Medical Corporation Barrier layer
US9801982B2 (en) 2004-09-28 2017-10-31 Atrium Medical Corporation Implantable barrier device
US8481080B2 (en) 2004-11-24 2013-07-09 Novozymes Biopolymer A/S Method of cross-linking hyaluronic acid with divinulsulfone
CN1325125C (zh) * 2004-12-23 2007-07-11 中国人民解放军第二军医大学 一种防粘连生物膜
ITTO20040918A1 (it) * 2004-12-29 2005-03-29 Luigi Ambrosio Idrogel polimerici superassorbenti biodegradabili e procedimento per la loro preparazione
WO2006089119A2 (en) * 2005-02-18 2006-08-24 Cartilix, Inc. Biological adhesive
CN101238151B (zh) 2005-08-04 2011-11-16 帝人株式会社 纤维素衍生物
US7323184B2 (en) * 2005-08-22 2008-01-29 Healagenics, Inc. Compositions and methods for the treatment of wounds and the reduction of scar formation
US9278161B2 (en) 2005-09-28 2016-03-08 Atrium Medical Corporation Tissue-separating fatty acid adhesion barrier
US9427423B2 (en) 2009-03-10 2016-08-30 Atrium Medical Corporation Fatty-acid based particles
EP1933991A4 (en) 2005-10-15 2012-05-02 Atrium Medical Corp HYDROPHOBIC NETWORKED GEL FOR BIOABSORBIBLE MEDICINAL CARRIER COVERS
US20070110788A1 (en) * 2005-11-14 2007-05-17 Hissong James B Injectable formulation capable of forming a drug-releasing device
MX2008009752A (es) 2006-02-03 2008-09-19 Tissuemed Ltd Materiales adhesivos a tejidos.
US20090018575A1 (en) * 2006-03-01 2009-01-15 Tissuemed Limited Tissue-adhesive formulations
WO2007108775A1 (en) * 2006-03-21 2007-09-27 Agency For Science, Technology And Research Cell-adhesive polyelectrolyte material for use as membrane and coating
EP2010117A4 (en) * 2006-04-12 2010-12-01 Massachusetts Inst Technology COMPOSITIONS AND METHODS FOR ADHESION INHIBITION
US7976873B2 (en) * 2006-05-10 2011-07-12 Medtronic Xomed, Inc. Extracellular polysaccharide solvating system for treatment of bacterial ear conditions
US20070264296A1 (en) * 2006-05-10 2007-11-15 Myntti Matthew F Biofilm extracellular polysachharide solvating system
US7993675B2 (en) * 2006-05-10 2011-08-09 Medtronic Xomed, Inc. Solvating system and sealant for medical use in the sinuses and nasal passages
US7959943B2 (en) * 2006-05-10 2011-06-14 Medtronics Xomed, Inc. Solvating system and sealant for medical use in the middle or inner ear
MX2008014847A (es) * 2006-05-31 2009-04-30 Baxter Int Metodo para crecimiento interno en la celula dirigido y regeneracion controlada de los tejidos en la cirugia espinal.
US8313762B2 (en) 2006-07-05 2012-11-20 Medtronic Xomed, Inc. Flexible bioresorbable hemostatic packing and stent
TWI436793B (zh) 2006-08-02 2014-05-11 Baxter Int 快速作用之乾密封膠及其使用和製造方法
ITMI20061726A1 (it) * 2006-09-11 2008-03-12 Fidia Farmaceutici Derivati crosslinkati a base di acido ialuronico reticolato via click chemistry
EP2083875B1 (en) 2006-11-06 2013-03-27 Atrium Medical Corporation Coated surgical mesh
US9492596B2 (en) 2006-11-06 2016-11-15 Atrium Medical Corporation Barrier layer with underlying medical device and one or more reinforcing support structures
US8114159B2 (en) 2006-11-20 2012-02-14 Depuy Spine, Inc. Anterior spinal vessel protector
US8455001B2 (en) 2007-02-06 2013-06-04 Teijin Limited Cellulose derivative and method for production thereof
JP5242921B2 (ja) * 2007-02-06 2013-07-24 帝人株式会社 ホスファチジルエタノールアミン結合多糖類の製造方法
US8088095B2 (en) 2007-02-08 2012-01-03 Medtronic Xomed, Inc. Polymeric sealant for medical use
US8658148B2 (en) 2007-06-22 2014-02-25 Genzyme Corporation Chemically modified dendrimers
GB0715514D0 (en) * 2007-08-10 2007-09-19 Tissuemed Ltd Coated medical devices
JP2011500237A (ja) 2007-10-30 2011-01-06 バクスター・インターナショナル・インコーポレイテッド 内臓または体腔壁の欠陥を治療するための再生性の生体機能性コラーゲン生物基質の使用
SI2818184T1 (sl) 2007-11-16 2019-03-29 Aclaris Therapeutics, Inc. Sestava in postopki za zdravljenje purpure
US9345809B2 (en) * 2007-11-28 2016-05-24 Fziomed, Inc. Carboxymethylcellulose polyethylene glycol compositions for medical uses
US8394782B2 (en) * 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having increased longevity
CN101878230B (zh) * 2007-12-19 2012-11-21 赢创高施米特有限公司 乳液中的交联透明质酸
EP2249891B1 (en) 2008-02-13 2016-05-25 The Cleveland Clinic Foundation Molecular enhancement of extracellular matrix and methods of use
US8668863B2 (en) 2008-02-26 2014-03-11 Board Of Regents, The University Of Texas System Dendritic macroporous hydrogels prepared by crystal templating
JP5569398B2 (ja) 2008-02-29 2014-08-13 フェッローサン メディカル ディバイス エー/エス 止血および/または創傷治癒を促進するための装置
US7842714B2 (en) * 2008-03-03 2010-11-30 Allergan, Inc. Ketorolac tromethamine compositions for treating ocular pain
US9192571B2 (en) * 2008-03-03 2015-11-24 Allergan, Inc. Ketorolac tromethamine compositions for treating or preventing ocular pain
WO2009135029A2 (en) * 2008-04-30 2009-11-05 The Cleveland Clinic Foundation Compositions and methods to treat urinary incontinence
US8932622B2 (en) * 2008-06-03 2015-01-13 Actamax Surgical Materials, Llc Tissue coating for preventing undesired tissue-to-tissue adhesions
CA2727432C (en) 2008-06-12 2016-10-11 Medtronic Xomed, Inc. Method for treating chronic wounds with an extracellular polymeric substance solvating system
US8450475B2 (en) 2008-08-04 2013-05-28 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
EP2311883A1 (en) * 2008-08-05 2011-04-20 Teijin Limited Hydrogel
CA2735173C (en) 2008-09-02 2017-01-10 Tautona Group Lp Threads of hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof
WO2010042427A2 (en) 2008-10-06 2010-04-15 Microbial Defense Systems, Llc Antimicrobial composition and methods of making and using same
US9039783B2 (en) * 2009-05-18 2015-05-26 Baxter International, Inc. Method for the improvement of mesh implant biocompatibility
PT2442835E (pt) * 2009-06-16 2015-03-23 Baxter Healthcare Sa Esponja hemostática
US20110038910A1 (en) 2009-08-11 2011-02-17 Atrium Medical Corporation Anti-infective antimicrobial-containing biomaterials
CN102753203A (zh) 2009-12-16 2012-10-24 巴克斯特国际公司 止血海绵
CN102665780B (zh) 2009-12-28 2015-04-22 川澄化学工业株式会社 防粘连材料
US9114188B2 (en) 2010-01-13 2015-08-25 Allergan, Industrie, S.A.S. Stable hydrogel compositions including additives
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
WO2011110894A2 (en) 2010-03-12 2011-09-15 Allergan Industrie Sas Fluid composition for improving skin conditions
HUE030138T2 (en) 2010-03-22 2017-04-28 Allergan Inc Crosslinked polysaccharide and protein polysaccharide hydrogels for soft tissue augmentation
SA111320355B1 (ar) 2010-04-07 2015-01-08 Baxter Heathcare S A إسفنجة لايقاف النزف
AU2011260274B2 (en) 2010-06-01 2015-07-02 Baxter Healthcare S.A. Process for making dry and stable hemostatic compositions
JP5973997B2 (ja) 2010-06-01 2016-08-23 バクスター・インターナショナル・インコーポレイテッドBaxter International Incorp0Rated 乾燥した安定な止血用組成物を作製するためのプロセス
US8940335B2 (en) 2010-06-01 2015-01-27 Baxter International Inc. Process for making dry and stable hemostatic compositions
WO2012009707A2 (en) 2010-07-16 2012-01-19 Atrium Medical Corporation Composition and methods for altering the rate of hydrolysis of cured oil-based materials
US8883139B2 (en) 2010-08-19 2014-11-11 Allergan Inc. Compositions and soft tissue replacement methods
US9005605B2 (en) 2010-08-19 2015-04-14 Allergan, Inc. Compositions and soft tissue replacement methods
US8889123B2 (en) 2010-08-19 2014-11-18 Allergan, Inc. Compositions and soft tissue replacement methods
JP6042815B2 (ja) 2010-10-08 2016-12-14 ザ ボード オブ リージェンツ オブ ザ ユニバーシティ オブ テキサス システム 生物医学的応用のためのアルギン酸塩及びヒアルロン酸を用いる抗癒着性バリア膜
US8946194B2 (en) 2010-10-08 2015-02-03 Board Of Regents, University Of Texas System One-step processing of hydrogels for mechanically robust and chemically desired features
EP2706845B1 (en) 2011-05-10 2021-06-23 Next Science IP Holdings Pty Ltd Antimicrobial solid and methods of making and using same
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
EP2714002B1 (en) 2011-06-03 2019-04-03 Allergan, Inc. Dermal filler compositions including antioxidants
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
ES2899992T3 (es) 2011-08-10 2022-03-15 Glycores 2000 Srl Acido hialurónico reticulado de bajo peso molecular resistente a la degradación
US9662422B2 (en) 2011-09-06 2017-05-30 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
US20130090291A1 (en) 2011-10-11 2013-04-11 Baxter Healthcare S.A. Hemostatic compositions
JP6195569B2 (ja) 2011-10-11 2017-09-13 バクスター・インターナショナル・インコーポレイテッドBaxter International Incorp0Rated 止血組成物
JP6038164B2 (ja) 2011-10-27 2016-12-07 バクスター・インターナショナル・インコーポレイテッドBaxter International Incorp0Rated 止血組成物
RU2657955C2 (ru) 2012-03-06 2018-06-18 Ферросан Медикал Дивайсиз А/С Контейнер под давлением, содержащий гемостатическую пасту
FR2988585B1 (fr) 2012-03-28 2015-04-03 Cousin Biotech Plaque viscerale destinee a la coelioscopie
EP2825216B1 (en) 2012-06-12 2015-08-19 Ferrosan Medical Devices A/S Dry haemostatic composition
US9867880B2 (en) 2012-06-13 2018-01-16 Atrium Medical Corporation Cured oil-hydrogel biomaterial compositions for controlled drug delivery
US11565027B2 (en) 2012-12-11 2023-01-31 Board Of Regents, The University Of Texas System Hydrogel membrane for adhesion prevention
CN104981259B (zh) 2012-12-11 2017-03-08 得克萨斯系统大学评议会 包含防粘连的水凝胶膜的试剂盒
AU2014212025A1 (en) 2013-02-01 2015-08-20 Allergan, Inc. Artificial tears comprising sodium hyaluronate and carboxymethylcellulose
US20140315828A1 (en) 2013-04-22 2014-10-23 Allergan, Inc. Cross-linked silk-hyaluronic acid compositions
JP6390873B2 (ja) 2013-06-21 2018-09-19 フェッローサン メディカル ディバイス エー/エス 減圧膨張させた乾燥組成物およびそれを保持するためのシリンジ
RU2678592C1 (ru) 2013-12-11 2019-01-30 Ферросан Медикал Дивайсиз А/С Сухая композиция, содержащая компонент, улучшающий экструзию
EP3200838B1 (en) 2014-09-30 2019-09-18 Allergan Industrie, SAS Stable hydrogel compositions including additives
US11046818B2 (en) 2014-10-13 2021-06-29 Ferrosan Medical Devices A/S Dry composition for use in haemostasis and wound healing
CN107206165B (zh) 2014-12-24 2020-10-23 弗罗桑医疗设备公司 用于保持并混合第一和第二物质的注射器
WO2016128783A1 (en) 2015-02-09 2016-08-18 Allergan Industrie Sas Compositions and methods for improving skin appearance
AU2016290433B2 (en) 2015-07-03 2018-05-24 Ferrosan Medical Devices A/S Syringe for mixing two components and for retaining a vacuum in a storage condition
CN105381501A (zh) * 2015-12-15 2016-03-09 日照天一生物医疗科技有限公司 可降解生物复合止血膜及其制备方法
CA3033536A1 (en) 2016-08-24 2018-03-01 Allergan, Inc. Co-crosslinked hyaluronic acid-silk fibroin hydrogels for improving tissue graft viability and for soft tissue augmentation
US11980700B2 (en) 2017-03-08 2024-05-14 Alafair Biosciences, Inc. Hydrogel medium for the storage and preservation of tissue
ES2968412T3 (es) 2018-05-09 2024-05-09 Ferrosan Medical Devices As Método para preparar una composición hemostática
JP7311983B2 (ja) * 2019-03-01 2023-07-20 大日本印刷株式会社 ゲル膜の製造方法およびゲル膜
JP7396804B2 (ja) * 2019-03-01 2023-12-12 大日本印刷株式会社 ゲル膜の製造方法およびゲル膜
RU2744752C1 (ru) * 2020-08-28 2021-03-15 Федеральное государственное бюджетное учреждение науки Институт проблем химико-энергетических технологий Сибирского отделения Российской академии наук (ИПХЭТ СО РАН) Способ получения противоспаечного материала
WO2023030435A1 (en) 2021-09-01 2023-03-09 Shanghai Qisheng Biological Preparation Co., Ltd. Cartilage regeneration using injectable, in situ polymerizable collagen compositions containing chondrocytes or stem cells
WO2023056433A1 (en) * 2021-10-01 2023-04-06 Northwestern University Supramolecular-covalent composite slurry for cartilage repair

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1238043A (en) * 1983-12-15 1988-06-14 Endre A. Balazs Water insoluble preparations of hyaluronic acid and processes therefor
SE442820B (sv) * 1984-06-08 1986-02-03 Pharmacia Ab Gel av tverbunden hyaluronsyra for anvendning som glaskroppssubstitut
SE456346B (sv) * 1984-07-23 1988-09-26 Pharmacia Ab Gel for att forhindra adhesion mellan kroppsvevnader och sett for dess framstellning
US4582865A (en) * 1984-12-06 1986-04-15 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
SE8501022L (sv) * 1985-03-01 1986-09-02 Pharmacia Ab Format alster och forfarande for dess framstellning
US4774093A (en) * 1985-06-25 1988-09-27 Fmc Corporation Polysaccharide compositions, preparation and uses
DE3684887D1 (de) * 1985-11-29 1992-05-21 Biomatrix Inc Arzneistoffabgabesysteme auf basis von hyaluronan, dessen derivaten und salzen sowie verfahren zu deren herstellung.
EP0244178A3 (en) * 1986-04-28 1989-02-08 Iolab, Inc Intraocular dosage compositions and method of use
US4795741A (en) * 1987-05-06 1989-01-03 Biomatrix, Inc. Compositions for therapeutic percutaneous embolization and the use thereof
EP0416250A3 (en) * 1989-08-01 1991-08-28 The Research Foundation Of State University Of New York N-acylurea and o-acylisourea derivatives of hyaluronic acid

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FI925802A (fi) 1992-12-21
US5017229A (en) 1991-05-21
ES2100954T3 (es) 1997-07-01
AU8392491A (en) 1992-01-23
EP0537292B1 (en) 1997-04-09
FI103381B (fi) 1999-06-30
GR3023436T3 (en) 1997-08-29
DE69125609D1 (de) 1997-05-15
ATE151294T1 (de) 1997-04-15
EP0537292A1 (en) 1993-04-21
NO306380B1 (no) 1999-11-01
NO924875L (no) 1992-12-16
AU660282B2 (en) 1995-06-22
WO1992000105A1 (en) 1992-01-09
FI925802A0 (fi) 1992-12-21
NO924875D0 (no) 1992-12-16
EP0537292A4 (en) 1993-07-28
DE69125609T2 (de) 1997-07-17
JP3399526B2 (ja) 2003-04-21
DK0537292T3 (da) 1997-08-04

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