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ES8707939A1 - Procedimiento para preparar derivados de n-carboxialquil-2--oxo-3-diaril-5,6-triazinas - Google Patents

Procedimiento para preparar derivados de n-carboxialquil-2--oxo-3-diaril-5,6-triazinas

Info

Publication number
ES8707939A1
ES8707939A1 ES550817A ES550817A ES8707939A1 ES 8707939 A1 ES8707939 A1 ES 8707939A1 ES 550817 A ES550817 A ES 550817A ES 550817 A ES550817 A ES 550817A ES 8707939 A1 ES8707939 A1 ES 8707939A1
Authority
ES
Spain
Prior art keywords
diaryl
oxo
carboxyalcoyl
therapeutic agents
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES550817A
Other languages
English (en)
Other versions
ES550817A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
Original Assignee
Pierre Fabre Medicament SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre Medicament SA filed Critical Pierre Fabre Medicament SA
Publication of ES550817A0 publication Critical patent/ES550817A0/es
Publication of ES8707939A1 publication Critical patent/ES8707939A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE TRIAZINAS, DE FORMULA (I). COMPRENDE LA REACCION DE UNA TRIAZINA DE FORMULA (II) CON UN COMPUESTO DE FORMULA R1-(O)1-N-CO-(O)N(A)N''X PARA OBTENER UN COMPUESTO DE FORMULA (I), EN LAS QUE A, R Y RK PUEDEN SER VARIOS TIPOS DE RADICALES, R1 REPRESENTA HIDROGENO O ALQUILO, X ES HALOGENO Y N Y NK VALEN 0 O 1. LA REACCION SE LLEVA A CABO EN UN DISOLVENTE INERTE, EN PRESENCIA DE UNA BASE, A UNA TEMPERATURA COMPRENDIDA ENTRE 20JC Y 70JC. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SUS PROPIEDADES ANTIINFLAMATORIAS.
ES550817A 1985-02-04 1986-01-13 Procedimiento para preparar derivados de n-carboxialquil-2--oxo-3-diaril-5,6-triazinas Expired ES8707939A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8501613A FR2576899A1 (fr) 1985-02-04 1985-02-04 N-carboxyalcoyl-2 oxo-3 diaryl 5-6 triazines utiles en therapeutique

Publications (2)

Publication Number Publication Date
ES550817A0 ES550817A0 (es) 1987-09-01
ES8707939A1 true ES8707939A1 (es) 1987-09-01

Family

ID=9315966

Family Applications (1)

Application Number Title Priority Date Filing Date
ES550817A Expired ES8707939A1 (es) 1985-02-04 1986-01-13 Procedimiento para preparar derivados de n-carboxialquil-2--oxo-3-diaril-5,6-triazinas

Country Status (10)

Country Link
US (1) US4677105A (es)
EP (1) EP0194164B1 (es)
JP (1) JPS61183273A (es)
AT (1) ATE61585T1 (es)
AU (1) AU568967B2 (es)
CA (1) CA1263391A (es)
DE (1) DE3678015D1 (es)
ES (1) ES8707939A1 (es)
FR (1) FR2576899A1 (es)
ZA (1) ZA86543B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5021415A (en) * 1990-02-13 1991-06-04 Bristol-Myers Squibb Co. Triazine carboxylic acids and esters
EP0442448A3 (en) 1990-02-13 1992-08-12 Bristol-Myers Squibb Company Heterocyclic carboxylic acids and esters
KR100271815B1 (ko) * 1996-05-28 2000-11-15 세구찌 류이찌 장궤식 차량의 주행장치

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2368278A1 (fr) * 1976-10-25 1978-05-19 Fabre Sa Pierre Nouveaux medicaments antalgiques contenant des triazines 1-2-4
NL7802514A (nl) * 1977-03-09 1978-09-12 Fabre Sa Pierre 5,6-diaryl-1,2,4-triazinederivaten en werkwijze ter bereiding van deze verbindingen.
FR2383176A1 (fr) * 1977-03-09 1978-10-06 Fabre Sa Pierre Amino aryl triazines 1-2-4 utilisables dans le traitement d'algies diverses
FR2478095A1 (fr) * 1980-03-14 1981-09-18 Fabre Sa Pierre Derives cetoniques de diaryl 5-6 triazines 1-2-4 antalgiques et antiagregants utilisables dans le traitement de fond des migraines
FR2500830A1 (fr) * 1981-03-02 1982-09-03 Fabre Sa Pierre Diaryl as-triazines fonctionnalisees en 2, leur procede de preparation et leur utilisation comme medicaments

Also Published As

Publication number Publication date
DE3678015D1 (en) 1991-04-18
EP0194164A2 (fr) 1986-09-10
US4677105A (en) 1987-06-30
EP0194164B1 (fr) 1991-03-13
ES550817A0 (es) 1987-09-01
AU5274086A (en) 1986-08-07
AU568967B2 (en) 1988-01-14
FR2576899A1 (fr) 1986-08-08
ATE61585T1 (de) 1991-03-15
CA1263391A (fr) 1989-11-28
EP0194164A3 (en) 1987-06-16
ZA86543B (en) 1986-09-24
JPS61183273A (ja) 1986-08-15

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