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ES8700658A1 - Un procedimiento para preparar compuestos relacionados con histargina - Google Patents

Un procedimiento para preparar compuestos relacionados con histargina

Info

Publication number
ES8700658A1
ES8700658A1 ES546669A ES546669A ES8700658A1 ES 8700658 A1 ES8700658 A1 ES 8700658A1 ES 546669 A ES546669 A ES 546669A ES 546669 A ES546669 A ES 546669A ES 8700658 A1 ES8700658 A1 ES 8700658A1
Authority
ES
Spain
Prior art keywords
preparation
compounds
histargin
medicaments
related compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES546669A
Other languages
English (en)
Other versions
ES546669A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Publication of ES546669A0 publication Critical patent/ES546669A0/es
Publication of ES8700658A1 publication Critical patent/ES8700658A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR COMPUESTOS RELACIONADOS CON HISTARGINA, DE FORMULA GENERAL (I). CONSISTE EN UNA SINTESIS ESCALONADA EN LA QUE SE HACE REACCIONAR UN COMPUESTO DE FORMULA GENERAL (II) CON UN A-AMINOACIDO, EN PRESENCIA DE UN DERIVADO DE BOROHIDRURO Y SEPARAR LOS GRUPOS PROTECTORES. LOS COMPUESTOS INHIBEN LA ACCION DE LA ENZIMA CONVERTIDORA DE LA ANGIOTENSINA Y PUEDEN UTILIZARSE COMO AGENTES ANTIHIPERTENSORES.-
ES546669A 1984-09-05 1985-09-03 Un procedimiento para preparar compuestos relacionados con histargina Expired ES8700658A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59184384A JPS6163661A (ja) 1984-09-05 1984-09-05 ヒスタジン関連化合物

Publications (2)

Publication Number Publication Date
ES546669A0 ES546669A0 (es) 1986-10-16
ES8700658A1 true ES8700658A1 (es) 1986-10-16

Family

ID=16152240

Family Applications (1)

Application Number Title Priority Date Filing Date
ES546669A Expired ES8700658A1 (es) 1984-09-05 1985-09-03 Un procedimiento para preparar compuestos relacionados con histargina

Country Status (8)

Country Link
EP (1) EP0175180A1 (es)
JP (1) JPS6163661A (es)
DK (1) DK403585A (es)
ES (1) ES8700658A1 (es)
GR (1) GR852138B (es)
HU (1) HUT40630A (es)
PT (1) PT81086B (es)
ZA (1) ZA856775B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4761483A (en) * 1985-06-26 1988-08-02 G. D. Searle & Co. Chloro-substituted ketone imidazole derivatives
US5424447A (en) * 1993-07-07 1995-06-13 The Medical College Of Wisconsin Research Foundation, Inc. Heme binding compounds and use thereof
DE69734783T2 (de) * 1996-07-24 2006-08-17 Buchardt, Dorte Peptidnukleinsäuren mit erhöhter bindungsaffinität, sequenzspezifität und löslichkeit
EP0851287B1 (en) * 1996-12-27 2002-03-27 Fuji Photo Film Co., Ltd. Aminopolycarboxylic acid-series chelating agent, heavy metal compound thereof, photographic additive, and processing method
HUP0303763A3 (en) * 2000-08-17 2004-06-28 Pfizer Substituted imidazoles as tafia inhibitors, process for their preparation and pharmaceutical compositions containing them

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59216597A (ja) * 1983-05-23 1984-12-06 Microbial Chem Res Found 新生理活性物質ヒスタジン

Also Published As

Publication number Publication date
ES546669A0 (es) 1986-10-16
PT81086B (en) 1987-03-31
GR852138B (es) 1986-01-03
JPH0577667B2 (es) 1993-10-27
DK403585D0 (da) 1985-09-04
HUT40630A (en) 1987-01-28
ZA856775B (en) 1986-04-30
DK403585A (da) 1986-03-06
EP0175180A1 (en) 1986-03-26
JPS6163661A (ja) 1986-04-01
PT81086A (en) 1985-10-01

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