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ES8700235A1 - Procedimiento para la obtencion de nuevos derivados de la piperidina - Google Patents

Procedimiento para la obtencion de nuevos derivados de la piperidina

Info

Publication number
ES8700235A1
ES8700235A1 ES543345A ES543345A ES8700235A1 ES 8700235 A1 ES8700235 A1 ES 8700235A1 ES 543345 A ES543345 A ES 543345A ES 543345 A ES543345 A ES 543345A ES 8700235 A1 ES8700235 A1 ES 8700235A1
Authority
ES
Spain
Prior art keywords
piperidine derivatives
image
denotes
preparation
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES543345A
Other languages
English (en)
Other versions
ES543345A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Sante SA
Original Assignee
Rhone Poulenc Sante SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante SA filed Critical Rhone Poulenc Sante SA
Publication of ES8700235A1 publication Critical patent/ES8700235A1/es
Publication of ES543345A0 publication Critical patent/ES543345A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Hydrogenated Pyridines (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE NUEVOS DERIVADOS DE PIPERIDINA DE FORMULA (I) EN EL QUE X REPRESENTA EL GRUPO -CHOH- Y AR UN CICLO AROMATICO SELECCIONADO ENTRE LOS CICLOS NAFTIL-1, ISOQUINOLEIL-1, DIMETOXI-6,7-ISOQUINOLEIL-1 Y (DIMETIL-1,1-ETIL)-2-QUINAZOLINIL-4-, ASI COMO DE SUS SALES DE ADICION CON ACIDOS MINERALES. CONSISTE EN REDUCIR LOS COMPUESTOS CORRESPONDIENTES EN EL QUE X ES EL GRUPO -CO-, CON UN HIDRURO METALICO REDUCTOR EN UN DISOLVENTE INERTE Y TRANSFORMARLOS EVENTUALMENTE EN LA SAL DE ADICION CON ACIDO. DE APLICACION EN EL TRATAMIENTO O PREVENCION DE TRASTORNOS DEL RITMO CARDIACO.
ES543345A 1984-03-09 1985-05-21 Procedimiento para la obtencion de nuevos derivados de la piperidina Expired ES8700235A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8403670A FR2560873B1 (fr) 1984-03-09 1984-03-09 Medicaments a base de derives de la piperidine, nouveaux derives de la piperidine et leurs procedes de preparation

Publications (2)

Publication Number Publication Date
ES8700235A1 true ES8700235A1 (es) 1986-10-01
ES543345A0 ES543345A0 (es) 1986-10-01

Family

ID=9301879

Family Applications (3)

Application Number Title Priority Date Filing Date
ES541109A Expired ES8602654A1 (es) 1984-03-09 1985-03-08 Procedimiento para la obtencion de nuevos derivados de la piperidina
ES543346A Granted ES543346A0 (es) 1984-03-09 1985-05-21 Procedimiento para la obtencion de nuevos derivados de la piperidina
ES543345A Expired ES8700235A1 (es) 1984-03-09 1985-05-21 Procedimiento para la obtencion de nuevos derivados de la piperidina

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES541109A Expired ES8602654A1 (es) 1984-03-09 1985-03-08 Procedimiento para la obtencion de nuevos derivados de la piperidina
ES543346A Granted ES543346A0 (es) 1984-03-09 1985-05-21 Procedimiento para la obtencion de nuevos derivados de la piperidina

Country Status (14)

Country Link
US (1) US4665076A (es)
EP (1) EP0173585B1 (es)
JP (1) JPS60204762A (es)
AT (1) ATE36705T1 (es)
AU (1) AU570541B2 (es)
CA (1) CA1217489A (es)
DE (1) DE3564572D1 (es)
DK (1) DK109285A (es)
ES (3) ES8602654A1 (es)
FR (1) FR2560873B1 (es)
HU (1) HU194846B (es)
IL (1) IL74533A (es)
MA (1) MA20369A1 (es)
ZA (1) ZA851698B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4921863A (en) * 1988-02-17 1990-05-01 Eisai Co., Ltd. Cyclic amine derivatives
GB9310582D0 (en) * 1993-05-22 1993-07-07 Smithkline Beecham Plc Pharmaceuticals
JP2006508113A (ja) * 2002-11-12 2006-03-09 ファイザー・プロダクツ・インク キノリン誘導体
US6894062B1 (en) 2002-11-12 2005-05-17 Pfizer Inc. Quinoline derivatives
CA2651732C (en) * 2006-05-18 2014-10-14 Mannkind Corporation Intracellular kinase inhibitors
CN106117138B (zh) * 2016-06-29 2018-06-15 云南中烟工业有限责任公司 一种具有抗菌活性的异喹啉生物碱类化合物、其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1197456B (de) * 1960-06-24 1965-07-29 Ruetgerswerke Ag Verfahren zur Herstellung von Vinyl-verbindungen der Pyridin- und Chinolinreihe
US3857847A (en) * 1968-07-02 1974-12-31 Hoffmann La Roche 6,7 substituted 4 (3{8 3(r) alkyl, 4(s)piperidyl{9 -2-oxopropyl)quinoline and racemates
BE791088A (fr) * 1971-11-09 1973-03-01 Richardson Merrell Inc Nouveaux derives d'aryl (piperidyl-4) cetone, utiles notamment comme analgesiques et anticoagulants, et leur procede de preparation
FR2443246A1 (fr) * 1978-12-05 1980-07-04 Pharmindustrie Nouveaux medicaments a base de derives de la phenyl-1 (piperidyl-4)-3 propanone-1
US4246268A (en) * 1979-02-09 1981-01-20 Richardson-Merrell Inc. Neuroleptic-4-(naphthylmethyl)piperidine derivatives

Also Published As

Publication number Publication date
EP0173585B1 (fr) 1988-08-24
ZA851698B (en) 1985-10-30
DK109285A (da) 1985-09-10
ES8603829A1 (es) 1986-01-01
AU3955785A (en) 1985-09-12
AU570541B2 (en) 1988-03-17
ES541109A0 (es) 1985-12-01
ES543346A0 (es) 1986-01-01
HUT37413A (en) 1985-12-28
MA20369A1 (fr) 1985-10-01
FR2560873B1 (fr) 1986-09-26
EP0173585A1 (fr) 1986-03-05
HU194846B (en) 1988-03-28
FR2560873A1 (fr) 1985-09-13
ES8602654A1 (es) 1985-12-01
DE3564572D1 (en) 1988-09-29
IL74533A (en) 1988-03-31
IL74533A0 (en) 1985-06-30
CA1217489A (fr) 1987-02-03
ATE36705T1 (de) 1988-09-15
ES543345A0 (es) 1986-10-01
DK109285D0 (da) 1985-03-08
JPS60204762A (ja) 1985-10-16
US4665076A (en) 1987-05-12

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