ES8609351A1 - Hydrosoluble antibiotic pharmaceutical compositions - Google Patents
Hydrosoluble antibiotic pharmaceutical compositionsInfo
- Publication number
- ES8609351A1 ES8609351A1 ES547625A ES547625A ES8609351A1 ES 8609351 A1 ES8609351 A1 ES 8609351A1 ES 547625 A ES547625 A ES 547625A ES 547625 A ES547625 A ES 547625A ES 8609351 A1 ES8609351 A1 ES 8609351A1
- Authority
- ES
- Spain
- Prior art keywords
- hydrosoluble
- pharmaceutical compositions
- antibiotic pharmaceutical
- antibiotic
- salified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000003115 biocidal effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 235000001014 amino acid Nutrition 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 2
- 239000004475 Arginine Substances 0.000 abstract 1
- XUJNEKJLAYXESH-REOHCLBHSA-N L-Cysteine Chemical compound SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 abstract 1
- AHLPHDHHMVZTML-BYPYZUCNSA-N L-Ornithine Chemical compound NCCC[C@H](N)C(O)=O AHLPHDHHMVZTML-BYPYZUCNSA-N 0.000 abstract 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 abstract 1
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 abstract 1
- 239000004472 Lysine Substances 0.000 abstract 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 abstract 1
- AHLPHDHHMVZTML-UHFFFAOYSA-N Orn-delta-NH2 Natural products NCCCC(N)C(O)=O AHLPHDHHMVZTML-UHFFFAOYSA-N 0.000 abstract 1
- UTJLXEIPEHZYQJ-UHFFFAOYSA-N Ornithine Natural products OC(=O)C(C)CCCN UTJLXEIPEHZYQJ-UHFFFAOYSA-N 0.000 abstract 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 abstract 1
- 235000018417 cysteine Nutrition 0.000 abstract 1
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229960003104 ornithine Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/65502—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a three-membered ring
- C07F9/65505—Phosphonic acids containing oxirane groups; esters thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The compositions contain salts of (-)cis-1,2-epoxypropylphosphonic acid with aminoacids e.g. arginine, ornithine, lysine, or cysteine and are characterised by containing an excess of a not salified aminoacid.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH4792/84A CH660306A5 (en) | 1984-10-05 | 1984-10-05 | WATER-SOLUBLE PHARMACEUTICAL COMPOSITIONS BASED ON SALTS OF (-)CIS-1,2-EPOXYPROPYLPHOSPHONIC ACID WITH AMINO ACIDS. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES547625A0 ES547625A0 (en) | 1986-09-01 |
ES8609351A1 true ES8609351A1 (en) | 1986-09-01 |
Family
ID=4282621
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES547625A Expired ES8609351A1 (en) | 1984-10-05 | 1985-10-04 | Hydrosoluble antibiotic pharmaceutical compositions |
Country Status (11)
Country | Link |
---|---|
JP (1) | JPS62223121A (en) |
KR (1) | KR860003012A (en) |
AT (1) | AT383736B (en) |
BE (1) | BE903369A (en) |
CH (1) | CH660306A5 (en) |
DE (1) | DE3535356A1 (en) |
ES (1) | ES8609351A1 (en) |
FR (1) | FR2571255B1 (en) |
GB (1) | GB2165152B (en) |
IT (1) | IT1201479B (en) |
NL (1) | NL8502712A (en) |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH310498A (en) * | 1951-11-14 | 1955-10-31 | Waldhof Zellstoff Fab | Process for stabilizing alkali salts of adenosine polyphosphoric acids. |
DE1767212B1 (en) * | 1967-04-13 | 1971-05-06 | Sumitomo Chemical Co | Process for making injectable drugs |
US3639590A (en) * | 1967-07-25 | 1972-02-01 | Merck & Co Inc | Antibacterial composition containing (-) (cis-1 2-epoxypropyl) phosphoric acid |
BE756953A (en) * | 1969-10-02 | 1971-04-01 | Merck & Co Inc | POTENTIALIZATION OF ANTIBIOTICS |
IT1161974B (en) * | 1978-02-02 | 1987-03-18 | Italchemi Spa | CIS.I 2 EPOXYPROPYLPHOSPHONIC ACID DERIVATIVES THEIR PREPARATION PROCEDURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
DE2813814A1 (en) * | 1978-03-31 | 1979-10-18 | Boehringer Mannheim Gmbh | Increasing the enteral reabsorption of pharmaceuticals - by administration together with an aminoacid or a peptide |
IT1112282B (en) * | 1978-07-19 | 1986-01-13 | Zambon Spa | Bis- (2-AMMONIUM-2-hydroxymethyl-1,3-propanediol) (2R-CIS) - (3-METILOSSIRANIL) phosphonate |
IT1097578B (en) * | 1978-07-31 | 1985-08-31 | Italchemi Spa | METHOD FOR PREPARING ACID SALTS (-) |
US4235900A (en) * | 1978-11-15 | 1980-11-25 | E. R. Squibb & Sons, Inc. | Cephradine compositions |
-
1984
- 1984-10-05 CH CH4792/84A patent/CH660306A5/en not_active IP Right Cessation
-
1985
- 1985-10-02 JP JP60219969A patent/JPS62223121A/en active Pending
- 1985-10-03 AT AT0287185A patent/AT383736B/en not_active IP Right Cessation
- 1985-10-03 DE DE19853535356 patent/DE3535356A1/en not_active Withdrawn
- 1985-10-04 IT IT22367/85A patent/IT1201479B/en active
- 1985-10-04 ES ES547625A patent/ES8609351A1/en not_active Expired
- 1985-10-04 BE BE2/60807A patent/BE903369A/en not_active IP Right Cessation
- 1985-10-04 GB GB08524550A patent/GB2165152B/en not_active Expired
- 1985-10-04 NL NL8502712A patent/NL8502712A/en not_active Application Discontinuation
- 1985-10-05 KR KR1019850007328A patent/KR860003012A/en not_active IP Right Cessation
- 1985-10-07 FR FR8514800A patent/FR2571255B1/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
IT8522367A0 (en) | 1985-10-04 |
ATA287185A (en) | 1987-01-15 |
GB8524550D0 (en) | 1985-11-06 |
GB2165152A (en) | 1986-04-09 |
GB2165152B (en) | 1988-03-16 |
FR2571255B1 (en) | 1988-09-16 |
BE903369A (en) | 1986-02-03 |
IT1201479B (en) | 1989-02-02 |
NL8502712A (en) | 1986-05-01 |
AT383736B (en) | 1987-08-10 |
DE3535356A1 (en) | 1986-04-24 |
FR2571255A1 (en) | 1986-04-11 |
ES547625A0 (en) | 1986-09-01 |
JPS62223121A (en) | 1987-10-01 |
KR860003012A (en) | 1986-05-19 |
CH660306A5 (en) | 1987-04-15 |
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