ES8502092A1 - Un procedimiento de resolucion de trans-d1-1-n-propil-6-oxodecahidroquinolina en sus isomeros opticos - Google Patents
Un procedimiento de resolucion de trans-d1-1-n-propil-6-oxodecahidroquinolina en sus isomeros opticosInfo
- Publication number
- ES8502092A1 ES8502092A1 ES524454A ES524454A ES8502092A1 ES 8502092 A1 ES8502092 A1 ES 8502092A1 ES 524454 A ES524454 A ES 524454A ES 524454 A ES524454 A ES 524454A ES 8502092 A1 ES8502092 A1 ES 8502092A1
- Authority
- ES
- Spain
- Prior art keywords
- resolved
- novel
- keto compounds
- keto
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
PROCEDIMIENTO DE RESOLUCION DE TRANS-D1-1-N-PROPIL-6-OXODECAHIDROQUINOLINA EN SUS ISOMEROS OPTICOS, COMPONENTES DE FORMULAS (I) O (II), Y SUS SALES DE ADICION DE ACIDOS.COMPRENDE LAS SIGUIENTES OPERACIONES: PRIMERA, SE PONE EN CONTACTO UNA SOLUCION DEL RACEMATO CON UNA SOLUCION QUE CONTIENE POR LO MENOS 0,5 EQUIVALENTES DE UN ACIDO DI-P-TOLUOILTARTARICO OPTICAMENTE ACTIVO; SEGUNDA, SE SEPARA LA SAL FORMADA DEL ISOMERO OPTICAMENTE ACTIVO; TERCERA, SE TRATA DICHA SAL CON UNA BASE; Y POR ULTIMO, SE AISLA EL ISOMERO OPTICAMENTE ACTIVO TRANS-1-N-PROPIL-6-OXODECAHIDROQUINOLINA DE LA MEZCLA.DE APLICACION EN EL TRATAMIENTO DEL SINDROME DE PARKINSON.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/439,107 US4471121A (en) | 1982-11-03 | 1982-11-03 | Method of resolving trans-d alpha-1-n-propyl-6-oxodecahydroquinoline and di-p-toluoyltartaric acid salts thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES524454A0 ES524454A0 (es) | 1984-12-16 |
| ES8502092A1 true ES8502092A1 (es) | 1984-12-16 |
Family
ID=23743321
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES524454A Expired ES8502092A1 (es) | 1982-11-03 | 1983-07-26 | Un procedimiento de resolucion de trans-d1-1-n-propil-6-oxodecahidroquinolina en sus isomeros opticos |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4471121A (es) |
| EP (1) | EP0112604A1 (es) |
| JP (1) | JPS5982365A (es) |
| KR (1) | KR860001506B1 (es) |
| AU (1) | AU557306B2 (es) |
| CA (1) | CA1198115A (es) |
| CS (1) | CS234050B2 (es) |
| DD (1) | DD210045A5 (es) |
| DK (1) | DK343183A (es) |
| ES (1) | ES8502092A1 (es) |
| FI (1) | FI832720A (es) |
| GB (1) | GB2129422B (es) |
| GR (1) | GR79600B (es) |
| HU (1) | HU189311B (es) |
| IL (1) | IL69360A (es) |
| NZ (1) | NZ205030A (es) |
| PH (1) | PH20193A (es) |
| PL (1) | PL243198A1 (es) |
| PT (1) | PT77113B (es) |
| RO (1) | RO86512B (es) |
| SU (1) | SU1282815A3 (es) |
| ZA (1) | ZA835502B (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL73001A0 (en) * | 1983-09-26 | 1984-12-31 | Lilly Co Eli | Improvements in and relating to 6-oxodecahydroquinolines |
| US4778894A (en) * | 1983-09-26 | 1988-10-18 | Eli Lilly And Company | 6 oxo-decahydroquinolines |
| US4764609A (en) * | 1986-03-31 | 1988-08-16 | Eli Lilly And Company | Synthesis of 2-aminopyrimido[4,5-g]quinolines |
| US5134143A (en) * | 1986-06-16 | 1992-07-28 | Eli Lilly And Company | BCD tricyclic ergoline part-structure analogues |
| US4977160A (en) * | 1986-06-16 | 1990-12-11 | Eli Lilly And Company | BCD tricyclic ergoline part-structure analogues |
| US4826986A (en) * | 1986-06-16 | 1989-05-02 | Eli Lilly And Company | 6-Oxo-trans-octa- and decahydroquinolines |
| FR2600649B1 (fr) * | 1986-06-26 | 1989-02-24 | Rhone Poulenc Sante | Procede de preparation du maleate acide de levomepromazine |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4230861A (en) * | 1979-01-22 | 1980-10-28 | Eli Lilly And Company | 1-And/or 7-substituted-6-hydroxy (or oxo)-3-decahydroquinoline carboxylic acids |
| US4198415A (en) * | 1979-01-22 | 1980-04-15 | Eli Lilly And Company | Prolactin inhibiting octahydro pyrazolo[3,4-g]quinolines |
-
1982
- 1982-11-03 US US06/439,107 patent/US4471121A/en not_active Expired - Fee Related
-
1983
- 1983-07-26 ES ES524454A patent/ES8502092A1/es not_active Expired
- 1983-07-27 CA CA000433400A patent/CA1198115A/en not_active Expired
- 1983-07-27 CS CS835634A patent/CS234050B2/cs unknown
- 1983-07-27 PH PH29306A patent/PH20193A/en unknown
- 1983-07-27 DK DK343183A patent/DK343183A/da not_active Application Discontinuation
- 1983-07-27 RO RO111745A patent/RO86512B/ro unknown
- 1983-07-27 GB GB08320249A patent/GB2129422B/en not_active Expired
- 1983-07-27 NZ NZ205030A patent/NZ205030A/en unknown
- 1983-07-27 DD DD83253426A patent/DD210045A5/de unknown
- 1983-07-27 HU HU832645A patent/HU189311B/hu unknown
- 1983-07-27 PT PT77113A patent/PT77113B/pt unknown
- 1983-07-27 AU AU17340/83A patent/AU557306B2/en not_active Ceased
- 1983-07-27 KR KR1019830003504A patent/KR860001506B1/ko active
- 1983-07-27 GR GR72054A patent/GR79600B/el unknown
- 1983-07-27 JP JP58138680A patent/JPS5982365A/ja active Pending
- 1983-07-27 SU SU833622809A patent/SU1282815A3/ru active
- 1983-07-27 IL IL69360A patent/IL69360A/xx unknown
- 1983-07-27 EP EP83304342A patent/EP0112604A1/en not_active Ceased
- 1983-07-27 FI FI832720A patent/FI832720A/fi not_active Application Discontinuation
- 1983-07-27 ZA ZA835502A patent/ZA835502B/xx unknown
- 1983-07-27 PL PL24319883A patent/PL243198A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT77113A (en) | 1983-08-01 |
| RO86512B (ro) | 1985-03-31 |
| EP0112604A1 (en) | 1984-07-04 |
| GR79600B (es) | 1984-10-31 |
| KR860001506B1 (ko) | 1986-09-30 |
| CA1198115A (en) | 1985-12-17 |
| PH20193A (en) | 1986-10-16 |
| GB2129422B (en) | 1986-08-20 |
| IL69360A (en) | 1986-10-31 |
| ES524454A0 (es) | 1984-12-16 |
| CS234050B2 (en) | 1985-03-14 |
| GB8320249D0 (en) | 1983-09-01 |
| RO86512A (ro) | 1985-03-15 |
| FI832720A (fi) | 1984-05-04 |
| ZA835502B (en) | 1985-03-27 |
| AU1734083A (en) | 1984-05-10 |
| DD210045A5 (de) | 1984-05-30 |
| NZ205030A (en) | 1986-03-14 |
| AU557306B2 (en) | 1986-12-18 |
| FI832720A0 (fi) | 1983-07-27 |
| PL243198A1 (en) | 1984-08-13 |
| US4471121A (en) | 1984-09-11 |
| DK343183D0 (da) | 1983-07-27 |
| PT77113B (en) | 1986-04-11 |
| KR840006626A (ko) | 1984-12-01 |
| JPS5982365A (ja) | 1984-05-12 |
| GB2129422A (en) | 1984-05-16 |
| DK343183A (da) | 1984-05-04 |
| SU1282815A3 (ru) | 1987-01-07 |
| HU189311B (en) | 1986-06-30 |
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