ES8308832A1 - Procedimiento para preparar derivados fluorados de diaminohepteno o -heptina. - Google Patents
Procedimiento para preparar derivados fluorados de diaminohepteno o -heptina.Info
- Publication number
- ES8308832A1 ES8308832A1 ES515094A ES515094A ES8308832A1 ES 8308832 A1 ES8308832 A1 ES 8308832A1 ES 515094 A ES515094 A ES 515094A ES 515094 A ES515094 A ES 515094A ES 8308832 A1 ES8308832 A1 ES 8308832A1
- Authority
- ES
- Spain
- Prior art keywords
- heptene
- diamino
- heptyne
- derivatives
- fluorinated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- UYXJVBAGMQWSOS-UHFFFAOYSA-N hept-1-ene-1,1-diamine Chemical class CCCCCC=C(N)N UYXJVBAGMQWSOS-UHFFFAOYSA-N 0.000 title abstract 2
- 102000052812 Ornithine decarboxylases Human genes 0.000 abstract 1
- 108700005126 Ornithine decarboxylases Proteins 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C211/09—Diamines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS FLUORADOS DE DIAMINO-HEPTENO O -HEPTINA Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE P VALE 1 O 2; E Y ES CH<2=CH- O CH=C-. CONSISTE EN LA REACCION DE ALQUILACION DE UN DERIVADO AMINO- Y ACETILENO- PROTEGIDO DE PROPARGILAMINA CON UN DERIVADO AMINO- PROTEGIDO DE UN HALURO DE FORMULA (II) EN LA QUE P VALE 1 O 2 Y X ES CLORO, BROMO O YODO; SEGUIDA DE LA EVENTUAL REDUCCION Y SEPARACION DE LOS GRUPOS PROTECTORES. LA ALQUILACION SE LLEVA A CABO EN UN DISOLVENTE INERTE A UNA TEMPERATURA NO SUPERIOR A -70 C. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL CONTROL DEL CRECIMIENTO O PROLIFERACION CELULAR INDESEABLE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8125357 | 1981-08-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8308832A1 true ES8308832A1 (es) | 1983-10-16 |
ES515094A0 ES515094A0 (es) | 1983-10-16 |
Family
ID=10524041
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES515094A Granted ES515094A0 (es) | 1981-08-19 | 1982-08-18 | Procedimiento para preparar derivados fluorados de diaminohepteno o -heptina. |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP0072760B1 (es) |
JP (1) | JPS5841844A (es) |
KR (1) | KR890000795B1 (es) |
AT (1) | ATE29487T1 (es) |
AU (1) | AU548094B2 (es) |
CA (1) | CA1202985A (es) |
DE (1) | DE3277199D1 (es) |
DK (1) | DK161021C (es) |
ES (1) | ES515094A0 (es) |
GB (1) | GB2104073B (es) |
GR (1) | GR77601B (es) |
IE (1) | IE54304B1 (es) |
IL (1) | IL66569A0 (es) |
NO (1) | NO153005C (es) |
NZ (1) | NZ201588A (es) |
PH (1) | PH18003A (es) |
ZA (1) | ZA825898B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4421768A (en) | 1982-08-11 | 1983-12-20 | Merrell Toraude Et Compagnie | Fluorinated diamino-heptene and-heptyne derivatives |
JPS60117791U (ja) * | 1984-01-18 | 1985-08-09 | 有限会社 名倉製作所 | カ−テン吊具 |
US4707498A (en) * | 1986-01-14 | 1987-11-17 | Merrell Dow Pharmaceuticals Inc. | Fluorinated diaminoalkyne derivatives |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4139563A (en) * | 1977-07-01 | 1979-02-13 | Merrell Toraude Et Compagnie | α-ACETYLENIC DERIVATIVES OF AMINES |
US4173971A (en) * | 1977-08-29 | 1979-11-13 | Karz Allen E | Continuous electrocardiogram monitoring method and system for cardiac patients |
US4134918A (en) * | 1977-09-06 | 1979-01-16 | Merrell Toraude Et Compagnie | Alpha-halomethyl derivatives of amines |
-
1982
- 1982-08-11 IE IE1944/82A patent/IE54304B1/en not_active IP Right Cessation
- 1982-08-13 ZA ZA825898A patent/ZA825898B/xx unknown
- 1982-08-13 CA CA000409406A patent/CA1202985A/en not_active Expired
- 1982-08-16 DE DE8282401537T patent/DE3277199D1/de not_active Expired
- 1982-08-16 AT AT82401537T patent/ATE29487T1/de active
- 1982-08-16 EP EP82401537A patent/EP0072760B1/en not_active Expired
- 1982-08-16 NZ NZ201588A patent/NZ201588A/en unknown
- 1982-08-17 AU AU87243/82A patent/AU548094B2/en not_active Ceased
- 1982-08-17 GB GB08223618A patent/GB2104073B/en not_active Expired
- 1982-08-18 IL IL66569A patent/IL66569A0/xx not_active IP Right Cessation
- 1982-08-18 KR KR8203711A patent/KR890000795B1/ko active
- 1982-08-18 NO NO822809A patent/NO153005C/no unknown
- 1982-08-18 ES ES515094A patent/ES515094A0/es active Granted
- 1982-08-18 DK DK370782A patent/DK161021C/da not_active IP Right Cessation
- 1982-08-19 GR GR69062A patent/GR77601B/el unknown
- 1982-08-19 PH PH27748A patent/PH18003A/en unknown
- 1982-08-19 JP JP57142786A patent/JPS5841844A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
KR890000795B1 (ko) | 1989-04-07 |
KR840001122A (ko) | 1984-03-28 |
AU8724382A (en) | 1983-02-24 |
NO822809L (no) | 1983-02-21 |
GB2104073B (en) | 1985-02-06 |
ZA825898B (en) | 1983-07-27 |
NO153005C (no) | 1986-01-02 |
DK161021B (da) | 1991-05-21 |
AU548094B2 (en) | 1985-11-21 |
NO153005B (no) | 1985-09-23 |
IE54304B1 (en) | 1989-08-16 |
CA1202985A (en) | 1986-04-08 |
NZ201588A (en) | 1985-02-28 |
EP0072760B1 (en) | 1987-09-09 |
IL66569A0 (en) | 1982-12-31 |
DK370782A (da) | 1983-02-20 |
GB2104073A (en) | 1983-03-02 |
IE821944L (en) | 1983-02-19 |
DK161021C (da) | 1991-10-28 |
EP0072760A1 (en) | 1983-02-23 |
ES515094A0 (es) | 1983-10-16 |
JPS5841844A (ja) | 1983-03-11 |
ATE29487T1 (de) | 1987-09-15 |
JPH0244298B2 (es) | 1990-10-03 |
PH18003A (en) | 1985-02-28 |
GR77601B (es) | 1984-09-25 |
DE3277199D1 (de) | 1987-10-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19970401 |