[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

ES8308880A1 - 10-(Aza-1-bicyclo(2,2,2)-octyl-3)-10H-phenothiazine-sulfonamide-2, and its derivatives. - Google Patents

10-(Aza-1-bicyclo(2,2,2)-octyl-3)-10H-phenothiazine-sulfonamide-2, and its derivatives.

Info

Publication number
ES8308880A1
ES8308880A1 ES513883A ES513883A ES8308880A1 ES 8308880 A1 ES8308880 A1 ES 8308880A1 ES 513883 A ES513883 A ES 513883A ES 513883 A ES513883 A ES 513883A ES 8308880 A1 ES8308880 A1 ES 8308880A1
Authority
ES
Spain
Prior art keywords
aza
reaction
fenotiazin
biciclo
octil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES513883A
Other languages
Spanish (es)
Other versions
ES513883A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmindustrie
Original Assignee
Pharmindustrie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmindustrie filed Critical Pharmindustrie
Publication of ES8308880A1 publication Critical patent/ES8308880A1/en
Publication of ES513883A0 publication Critical patent/ES513883A0/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Abstract

A PROCEDURE FOR THE PREPARATION OF 10-1-AZA- (2,2,2) -BICICLO-3-OCTIL -10H-FENOTIAZIN-2-SULFONAMIDAS. THE FOLLOWING STAGES ARE PERFORMED: 1) REACTION OF N, N-DIMETIL 10- 1-AZA- (2,2,2) -BICICLO-3-OCTIL -10H-FENOTIAZIN-2- -SULFONAMIDA WITH ALCALINOINE METAL ALCOHOLATE IN A SOLVENT. 2) REACTION OF THE SULPHINATE OBTAINED THROUGH AN OXIDIZER IN AQUEOUS ACID; IT IS ALKANIZED THROUGH AN ALKALINE METAL HYDROXIDE AND THE ACID SALT OBTAINED FROM THE ACTION OF THIONYL CHLORIDE IS SUBMITTED. 3) REACTION OF THE MIXTURE UNDERSTANDING SULPHONYL CHLORIDE WITH R-NH <2. COMPOUNDS ARE OBTAINED (I), IN WHICH R IS HYDROGEN OR A RENT GROUP. (Machine-translation by Google Translate, not legally binding)
ES513883A 1981-07-10 1982-07-09 10- (1-AZA- (2,2,2) -BICICLO-3-OCTIL) 10 H-FENOTIAZIN-2-SULFONAMIDAS. Granted ES513883A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8113602A FR2509307A1 (en) 1981-07-10 1981-07-10 (AZA-1 BICYCLO- (2,2,2) OCTYL-3) 10H PHENOTHIAZINE-SULFONAMIDE-2, ITS DERIVATIVES, PROCESS FOR PREPARING THEM AND THEIR USE AS MEDICAMENTS

Publications (2)

Publication Number Publication Date
ES8308880A1 true ES8308880A1 (en) 1983-10-01
ES513883A0 ES513883A0 (en) 1983-10-01

Family

ID=9260427

Family Applications (1)

Application Number Title Priority Date Filing Date
ES513883A Granted ES513883A0 (en) 1981-07-10 1982-07-09 10- (1-AZA- (2,2,2) -BICICLO-3-OCTIL) 10 H-FENOTIAZIN-2-SULFONAMIDAS.

Country Status (14)

Country Link
US (1) US4451461A (en)
EP (1) EP0070753A1 (en)
JP (1) JPS5818382A (en)
AU (1) AU8578282A (en)
DK (1) DK308582A (en)
ES (1) ES513883A0 (en)
FI (1) FI822455L (en)
FR (1) FR2509307A1 (en)
GR (1) GR69437B (en)
IL (1) IL65994A0 (en)
MA (1) MA19527A1 (en)
NO (1) NO822395L (en)
PT (1) PT75162B (en)
ZA (1) ZA824873B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8413915D0 (en) * 1984-05-31 1984-07-04 Wellcome Found Phenothiazine compounds
US5506247A (en) * 1988-04-15 1996-04-09 T Cell Sciences, Inc. Compounds that inhibit complement and/or suppress immune activity
US5191078A (en) * 1989-12-21 1993-03-02 Zambon Group S.P.A. Process for the direct and regioselective functionalization in position 2 of phenothiazine
IT1237209B (en) * 1989-12-21 1993-05-27 Zambon Spa PROCESS FOR DIRECT AND REGIO-SELECTIVE FUNCTIONALIZATION IN POSITION 2 OF PHENOTHIAZINE
US6834636B2 (en) 1999-03-23 2004-12-28 Thomas Engine Company Single-ended barrel engine with double-ended, double roller pistons
JP4720518B2 (en) * 2006-01-20 2011-07-13 株式会社ケンウッド Electronic equipment housing structure

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1250534A (en) * 1969-03-03 1971-10-20
US3987042A (en) * 1969-03-03 1976-10-19 Claude Gueremy Phenothiazine derivative
FR2318638A2 (en) * 1975-07-25 1977-02-18 Sogeras NEW DERIVATIVES OF PHENOTHIAZINE AND PROCESS FOR THEIR PREPARATION

Also Published As

Publication number Publication date
GR69437B (en) 1982-06-18
US4451461A (en) 1984-05-29
FI822455L (en) 1983-01-11
ES513883A0 (en) 1983-10-01
NO822395L (en) 1983-01-11
FR2509307A1 (en) 1983-01-14
ZA824873B (en) 1983-04-27
JPS5818382A (en) 1983-02-02
FI822455A0 (en) 1982-07-09
EP0070753A1 (en) 1983-01-26
PT75162B (en) 1984-02-21
MA19527A1 (en) 1983-04-01
PT75162A (en) 1982-07-01
IL65994A0 (en) 1982-09-30
FR2509307B1 (en) 1984-03-30
AU8578282A (en) 1983-01-13
DK308582A (en) 1983-01-11

Similar Documents

Publication Publication Date Title
ES8700254A1 (en) Aminoalkoxybenzopyranones and processes for the production thereof.
ES8604126A1 (en) A process for the preparation of p-isononanoyloxybenzenenesulphonate.
ES8802039A1 (en) 1-Piperazine carboxamide derivatives, their preparation and their use in pharmaceutical compositions.
ES8308880A1 (en) 10-(Aza-1-bicyclo(2,2,2)-octyl-3)-10H-phenothiazine-sulfonamide-2, and its derivatives.
GB1111988A (en) 2&#39;,3&#39;-dideoxyriboside-2&#39;,3&#39;-olefins
GB1492718A (en) Benzothiazine 1,1-dioxide derivatives
DE3060919D1 (en) Isoxazolecarboxylic acid anilides, their preparation, fungicidal compositions and process for combating fungi
JPS5551054A (en) Cysteine derivative
ES477878A1 (en) Mercaptoacylamino acids
ES466127A1 (en) 4&#34;-deoxyvincristine and related compounds
JPS5581818A (en) Method of fluorination
JPS52131544A (en) Phenoxymalonic acid derivatives and herbicides containing them
GB1473289A (en) Process for the alpha-chlorination of alkyl chloroaromatic compounds
GB1525547A (en) Process for producing a gamma-lactone
KR830008993A (en) Method for preparing mercaptoacyl-carnitine
GB1161093A (en) 1,2,5-Thiadiazole Derivatives
JPS527819A (en) Process for smooth electrodeposition of copper
CH614932A5 (en) Process for the preparation of new terpenoaromatic amidines
IE41394B1 (en) Substituted benimidazoles
JPS5214721A (en) Process for preparation of sodium malate hydrate
JPS5430128A (en) Preparation of water impregnated substance of diperisophthalic acid tent-butyl ester
GB2009224A (en) Process for The Manufacture of O-Benzyl Toluenes
ES8406428A1 (en) Process for the preparation of aryloxybenzoic acids containing a sulfonamide group
ES8305362A1 (en) A procedure for preparing derivatives of antibioticos-lactamicos. (Machine-translation by Google Translate, not legally binding)
JPS5212151A (en) Process for preparation of alkyladamantane

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19980202