ES8307377A1 - Detection of human cancer cells with antibodies to human cancer cell nucleolar antigen(s) - Google Patents
Detection of human cancer cells with antibodies to human cancer cell nucleolar antigen(s)Info
- Publication number
- ES8307377A1 ES8307377A1 ES509239A ES509239A ES8307377A1 ES 8307377 A1 ES8307377 A1 ES 8307377A1 ES 509239 A ES509239 A ES 509239A ES 509239 A ES509239 A ES 509239A ES 8307377 A1 ES8307377 A1 ES 8307377A1
- Authority
- ES
- Spain
- Prior art keywords
- human cancer
- antibodies
- nucleolar antigen
- cancer cells
- detection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57496—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving intracellular compounds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Food Science & Technology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Detergent Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Specific nucleolar antigen(s) are found common to a broad range of human malignant tumor specimens and have been isolated, extracted and purified. Antibodies and antisera specific to these nucleolar antigen(s) are harvested from non-human hosts and used for detection of human cancer cells. Disclosed are (1) methods for isolating the nucleolar antigen(s), obtaining them in substantially purified form, producing the specific antibodies, obtaining them in substantially purified form, and using the antisera and antibodies induced by the nucleolar antigen(s) in diagnostic procedures for detecting human cancer cells, and (2) diagnostic kits comprising specific antibodies and antisera.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA000343088A CA1157373A (en) | 1980-01-04 | 1980-01-04 | Detection of human cancer cells with antibodies to human cancer nucleolar antigen(s) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES509239A0 ES509239A0 (en) | 1983-06-16 |
| ES8307377A1 true ES8307377A1 (en) | 1983-06-16 |
Family
ID=4115973
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES498305A Granted ES498305A0 (en) | 1980-01-04 | 1981-01-02 | A PROCEDURE FOR THE PREPARATION OF ANTIBODIES WITH SPECIALTY AGAINST ANTIGENS FOUND IN THE NUCLEUS AND NU-CLEOLOS OF CANCER HUMAN CELLS. |
| ES509239A Expired ES8307377A1 (en) | 1980-01-04 | 1982-02-01 | Detection of human cancer cells with antibodies to human cancer cell nucleolar antigen(s) |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES498305A Granted ES498305A0 (en) | 1980-01-04 | 1981-01-02 | A PROCEDURE FOR THE PREPARATION OF ANTIBODIES WITH SPECIALTY AGAINST ANTIGENS FOUND IN THE NUCLEUS AND NU-CLEOLOS OF CANCER HUMAN CELLS. |
Country Status (27)
| Country | Link |
|---|---|
| JP (1) | JPS56101553A (en) |
| KR (1) | KR850001770B1 (en) |
| AR (1) | AR232046A1 (en) |
| AT (1) | AT373397B (en) |
| AU (1) | AU535024B2 (en) |
| BE (1) | BE886935A (en) |
| CA (1) | CA1157373A (en) |
| CH (1) | CH659328A5 (en) |
| DE (1) | DE3047654A1 (en) |
| DK (1) | DK554980A (en) |
| ES (2) | ES498305A0 (en) |
| FI (1) | FI810007L (en) |
| FR (1) | FR2484650B1 (en) |
| GB (1) | GB2067286B (en) |
| GR (1) | GR72850B (en) |
| IE (1) | IE50760B1 (en) |
| IL (1) | IL61641A (en) |
| IT (1) | IT1172216B (en) |
| LU (1) | LU83015A1 (en) |
| NL (1) | NL8007128A (en) |
| NO (2) | NO803910L (en) |
| NZ (1) | NZ195756A (en) |
| OA (1) | OA06713A (en) |
| PH (5) | PH18765A (en) |
| PT (1) | PT72301B (en) |
| SE (1) | SE450665B (en) |
| ZA (1) | ZA807754B (en) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4487830A (en) * | 1982-05-14 | 1984-12-11 | American Hoechst Corporation | Enzyme/immunofluorescent assay for autoantibodies |
| JPS5990052A (en) * | 1982-11-16 | 1984-05-24 | Katsu Taniguchi | Melanoma diagnosis medicine using monoclonal specific antibody |
| US4871661A (en) * | 1983-11-23 | 1989-10-03 | The Ohio State University Research Foundation | Process for testing the carcinogenicity of a material or the presence of cancer-inducing factors in an environment |
| EP0145373B1 (en) * | 1983-11-23 | 1992-03-25 | The Ohio State University Research Foundation | Purification of cancer-associated protein and preparation of antibody thereto |
| US4746539A (en) * | 1983-11-23 | 1988-05-24 | The Ohio State University Research Foundation | Purification of cancer-associated protein and preparation of antibody thereto |
| US4645737A (en) * | 1984-03-05 | 1987-02-24 | American Hoechst Corporation | Enzyme/immunofluorescent assay for anti-treponemal antibodies |
| US4607008A (en) * | 1984-03-05 | 1986-08-19 | American Hoechst Corporation | Enzyme/immunofluorescent assay for anti-Epstein-Barr Virus antibodies |
| ATE76509T1 (en) * | 1984-05-02 | 1992-06-15 | Univ Research Corp | IMMUNOLOGICAL TEST PROCEDURE OF A PROCOAGULATING ENZYME FOR THE DETECTION OF CANCER. |
| US4616658A (en) * | 1985-02-27 | 1986-10-14 | William Shell | Non-radioactively labeled microspheres and use of same to measure blood flow |
| US4798719A (en) * | 1986-09-11 | 1989-01-17 | University Of Pittsburgh | Method for selection of antigens suitable as in vivo targets for antibodies |
| US5019368A (en) * | 1989-02-23 | 1991-05-28 | Cancer Biologics, Inc. | Detection of necrotic malignant tissue and associated therapy |
| US4861581A (en) * | 1986-12-05 | 1989-08-29 | Cancer Biologics, Inc. | Detection of necrotic malignant tissue and associated therapy |
| CA2023030A1 (en) * | 1990-07-13 | 1992-01-14 | Robert R. Guerrero | In vitro method and probe for detecting the presence of the ring shaped particle and malignancy in humans and animals |
-
1980
- 1980-01-04 CA CA000343088A patent/CA1157373A/en not_active Expired
- 1980-12-04 AU AU65070/80A patent/AU535024B2/en not_active Ceased
- 1980-12-04 IE IE2533/80A patent/IE50760B1/en unknown
- 1980-12-04 NZ NZ195756A patent/NZ195756A/en unknown
- 1980-12-05 IL IL61641A patent/IL61641A/en unknown
- 1980-12-10 ZA ZA00807754A patent/ZA807754B/en unknown
- 1980-12-15 PH PH24978A patent/PH18765A/en unknown
- 1980-12-17 DE DE19803047654 patent/DE3047654A1/en active Granted
- 1980-12-18 LU LU83015A patent/LU83015A1/en unknown
- 1980-12-22 NO NO803910A patent/NO803910L/en unknown
- 1980-12-22 AR AR283753A patent/AR232046A1/en active
- 1980-12-27 JP JP18948880A patent/JPS56101553A/en active Pending
- 1980-12-29 DK DK554980A patent/DK554980A/en not_active Application Discontinuation
- 1980-12-30 CH CH9652/80A patent/CH659328A5/en not_active IP Right Cessation
- 1980-12-30 KR KR1019800005026A patent/KR850001770B1/en active
- 1980-12-31 NL NL8007128A patent/NL8007128A/en not_active Application Discontinuation
- 1980-12-31 BE BE0/203378A patent/BE886935A/en not_active IP Right Cessation
- 1980-12-31 PT PT72301A patent/PT72301B/en unknown
- 1980-12-31 GB GB8041638A patent/GB2067286B/en not_active Expired
-
1981
- 1981-01-02 SE SE8100011A patent/SE450665B/en not_active IP Right Cessation
- 1981-01-02 ES ES498305A patent/ES498305A0/en active Granted
- 1981-01-02 FR FR8100014A patent/FR2484650B1/en not_active Expired
- 1981-01-02 FI FI810007A patent/FI810007L/en not_active Application Discontinuation
- 1981-01-05 GR GR63789A patent/GR72850B/el unknown
- 1981-01-05 OA OA57289A patent/OA06713A/en unknown
- 1981-01-05 IT IT67001/81A patent/IT1172216B/en active
- 1981-01-05 AT AT0001081A patent/AT373397B/en not_active IP Right Cessation
-
1982
- 1982-02-01 ES ES509239A patent/ES8307377A1/en not_active Expired
-
1983
- 1983-02-21 PH PH28549A patent/PH18636A/en unknown
- 1983-02-21 PH PH28550A patent/PH18129A/en unknown
- 1983-02-21 PH PH28548A patent/PH18624A/en unknown
- 1983-02-21 PH PH28547A patent/PH18637A/en unknown
-
1985
- 1985-01-02 NO NO850005A patent/NO850005L/en unknown
Also Published As
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