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ES8306752A1 - Un procedimiento para la preparacion de nuevos derivados de benzamina. - Google Patents

Un procedimiento para la preparacion de nuevos derivados de benzamina.

Info

Publication number
ES8306752A1
ES8306752A1 ES513125A ES513125A ES8306752A1 ES 8306752 A1 ES8306752 A1 ES 8306752A1 ES 513125 A ES513125 A ES 513125A ES 513125 A ES513125 A ES 513125A ES 8306752 A1 ES8306752 A1 ES 8306752A1
Authority
ES
Spain
Prior art keywords
alkyl
hydrogen
phenyl
alkylenedioxy
alkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES513125A
Other languages
English (en)
Other versions
ES513125A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES8306752A1 publication Critical patent/ES8306752A1/es
Publication of ES513125A0 publication Critical patent/ES513125A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE BENZAMIDA, Y DE SUS SALES Y N-OXIDOS Y ADUCTOS DISOLVENTES FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE M, N Y P VALEN 0-3; Y R -R Y R PUEDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III), EN LAS QUE R , R -R , M, N Y P TIENEN LOS MISMOS SIGNIFICADOS QUE EN LA FORMULA (I), Q ES UN GRUPO SALIENTE, Y R Y R PUEDEN SER VARIOS RADICALES. LA REACCION SE LLEVA A CABO EN UN DISOLVENTE INERTE NO HIDROXILICO, EN PRESENCIA DE UN CATALIZADOR DESHIDRATANTE, O DE UN ACEPTOR DE ACIDO, A UNA TEMPERATURA ENTRE -10 C Y 100 C. ESTOS COMPUESTOS TIENEN APLICACIONES PARA EL TRATAMIENTO DE TRANSTORNOS DE LA FUNCION GASTRO-INTESTINAL Y DE EMESIS.
ES513125A 1981-06-16 1982-06-15 Un procedimiento para la preparacion de nuevos derivados de benzamina. Granted ES513125A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8118483 1981-06-16
GB8132416 1981-10-28

Publications (2)

Publication Number Publication Date
ES8306752A1 true ES8306752A1 (es) 1983-06-01
ES513125A0 ES513125A0 (es) 1983-06-01

Family

ID=26279812

Family Applications (1)

Application Number Title Priority Date Filing Date
ES513125A Granted ES513125A0 (es) 1981-06-16 1982-06-15 Un procedimiento para la preparacion de nuevos derivados de benzamina.

Country Status (3)

Country Link
EP (1) EP0067565A1 (es)
AU (1) AU8488782A (es)
ES (1) ES513125A0 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0094744A1 (en) * 1982-04-23 1983-11-23 Beecham Group Plc Azabicyclobenzamides, their preparation and their pharmaceutical compositions
ZW17385A1 (en) * 1984-11-06 1986-02-19 Hoffmann La Roche Tricyclic pyridine derivatives
US4689329A (en) * 1986-02-04 1987-08-25 Mcneilab, Inc. 5-substituted octahydroindolizine analgesics compounds and 7-keto intermediates
GB8607163D0 (en) * 1986-03-22 1986-04-30 Beecham Group Plc Chemical compound
US4863919A (en) * 1988-02-01 1989-09-05 A. H. Robins Company, Incorporated Method of enhancing memory or correcting memory deficiency with arylamido(and arylthiomido)-azabicycloalkanes
GB9817028D0 (en) * 1998-08-05 1998-09-30 Smithkline Beecham Plc Novel compounds
US8143273B2 (en) * 2010-06-22 2012-03-27 Hoffman-La Roche Inc. Quinolizidine and indolizidine derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1593146A (en) * 1976-11-05 1981-07-15 Beecham Group Ltd Octahydro-quinolizinyl benzamide derivatives
IL59004A0 (en) * 1978-12-30 1980-03-31 Beecham Group Ltd Substituted benzamides their preparation and pharmaceutical compositions containing them
EP0036269A1 (en) * 1980-03-15 1981-09-23 Beecham Group Plc Substituted benzamides

Also Published As

Publication number Publication date
EP0067565A1 (en) 1982-12-22
AU8488782A (en) 1982-12-23
ES513125A0 (es) 1983-06-01

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