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ES8305693A1 - Procedimiento para la obtencion de derivados del 3-amino-1, 2-propandiol - Google Patents

Procedimiento para la obtencion de derivados del 3-amino-1, 2-propandiol

Info

Publication number
ES8305693A1
ES8305693A1 ES514369A ES514369A ES8305693A1 ES 8305693 A1 ES8305693 A1 ES 8305693A1 ES 514369 A ES514369 A ES 514369A ES 514369 A ES514369 A ES 514369A ES 8305693 A1 ES8305693 A1 ES 8305693A1
Authority
ES
Spain
Prior art keywords
derivatives
amino
formula
image
propane diol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES514369A
Other languages
English (en)
Other versions
ES514369A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES8305693A1 publication Critical patent/ES8305693A1/es
Publication of ES514369A0 publication Critical patent/ES514369A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/12Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/041,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/121,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/141,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/201,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 4
    • C07D265/22Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/22Radicals substituted by singly bound oxygen or sulfur atoms etherified

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DEL 3-AMINO-1,2-PROPANDIOL, DE FORMULA (I), EN LA QUE R ES PROLIHIDROXI-ALQUILO INFERIOR Y ALK ES UN RADICAL -CH -CH O CH -CH-CH -. CONSISTE EN LA REACCION DE DISOCIACION DE LOS GRUPOS PROTECTORES DEL NITROGENO Y/O DE LOS ATOMOS DE OXIGENO, DE UN COMPUESTO DE FORMULA (II), EN LA QUE ALK TIENE EL MISMO SIGNIFICADO QUE EN LA FORMULA (I), Y R ES UN GRUPO POLIHIDROXI-ALQUILO INFERIOR, EN EL QUE AL MENOS UNO DE LOS GRUPOS HIDROXI Y/O AMINO SE ENCUENTRAN PROTEGIDOS. LA REACCION SE EFECTUA POR TRATAMIENTO CON AGUA EN CONDICIONES ACIDAS O BASICAS. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE IRREGULARIDADES EN EL RITMO CARDIACO, ANGINA DE PECHO Y DE LA HIPERTONIA.
ES514369A 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1, 2-propandiol Granted ES514369A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH611880 1980-08-13

Publications (2)

Publication Number Publication Date
ES8305693A1 true ES8305693A1 (es) 1983-05-01
ES514369A0 ES514369A0 (es) 1983-05-01

Family

ID=4304561

Family Applications (8)

Application Number Title Priority Date Filing Date
ES504682A Granted ES504682A0 (es) 1980-08-13 1981-08-11 Procedimiento para la obtencion de derivados del 3-amino-1,2propandiol
ES514368A Granted ES514368A0 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1, 2-propandiol
ES514365A Granted ES514365A0 (es) 1980-08-13 1982-07-26 Procedimiento para obtencion de derivados del 3-amino-1,2- propandiol.
ES514366A Granted ES514366A0 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1,2-propandiol.
ES514369A Granted ES514369A0 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1, 2-propandiol
ES514367A Expired ES8305691A1 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1, 2-propandiol
ES514370A Expired ES8306473A1 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1 2-propandiol
ES514371A Expired ES8305694A1 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1, s-propandiol

Family Applications Before (4)

Application Number Title Priority Date Filing Date
ES504682A Granted ES504682A0 (es) 1980-08-13 1981-08-11 Procedimiento para la obtencion de derivados del 3-amino-1,2propandiol
ES514368A Granted ES514368A0 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1, 2-propandiol
ES514365A Granted ES514365A0 (es) 1980-08-13 1982-07-26 Procedimiento para obtencion de derivados del 3-amino-1,2- propandiol.
ES514366A Granted ES514366A0 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1,2-propandiol.

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES514367A Expired ES8305691A1 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1, 2-propandiol
ES514370A Expired ES8306473A1 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1 2-propandiol
ES514371A Expired ES8305694A1 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1, s-propandiol

Country Status (17)

Country Link
EP (1) EP0045964A1 (es)
JP (1) JPS5759842A (es)
KR (1) KR840002266B1 (es)
AR (6) AR231273A1 (es)
AU (1) AU543647B2 (es)
CA (1) CA1192221A (es)
DD (3) DD202691A5 (es)
DK (1) DK358381A (es)
ES (8) ES504682A0 (es)
FI (1) FI812465L (es)
GR (1) GR74992B (es)
HU (1) HU186342B (es)
IL (1) IL63539A (es)
NO (1) NO812736L (es)
NZ (1) NZ198020A (es)
PT (1) PT73511B (es)
ZA (1) ZA815554B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE58417B1 (en) * 1984-04-27 1993-09-22 Ici Plc Chemical derivatives
GB201101959D0 (en) * 2011-02-04 2011-03-23 Univ Nottingham Novel ether linked compoundsand improved treatments for cardiac and cardiovascular disease

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1398738A (en) * 1972-12-05 1975-06-25 Pfizer Ltd Propanolamine derivatives
DD144050A5 (de) * 1978-06-05 1980-09-24 Ciba Geigy Ag Verfahren zur herstellung von n-alkylierten aminoalkoholen
DD150456A5 (de) * 1979-03-01 1981-09-02 Ciba Geigy Ag Verfahren zur herstellung von derivaten des 3-amino-1,2-propandiols

Also Published As

Publication number Publication date
ES514367A0 (es) 1983-04-16
PT73511A (en) 1981-09-01
KR830006173A (ko) 1983-09-17
ES8305692A1 (es) 1983-05-01
KR840002266B1 (ko) 1984-12-14
ES514370A0 (es) 1983-06-01
EP0045964A1 (de) 1982-02-17
ES8305690A1 (es) 1983-05-01
CA1192221A (en) 1985-08-20
PT73511B (en) 1983-07-06
DD202691A5 (de) 1983-09-28
ES8301462A1 (es) 1982-12-01
IL63539A (en) 1984-11-30
ES514371A0 (es) 1983-05-01
ES8305694A1 (es) 1983-05-01
FI812465L (fi) 1982-02-14
NO812736L (no) 1982-02-15
ES514368A0 (es) 1983-05-01
ES8305691A1 (es) 1983-04-16
NZ198020A (en) 1985-04-30
ES8305689A1 (es) 1983-04-16
IL63539A0 (en) 1981-11-30
AR231278A1 (es) 1984-10-31
AU543647B2 (en) 1985-04-26
DD202532A5 (de) 1983-09-21
JPS5759842A (en) 1982-04-10
AU7402081A (en) 1982-02-18
AR231275A1 (es) 1984-10-31
GR74992B (es) 1984-07-12
ES514366A0 (es) 1983-05-01
ES514369A0 (es) 1983-05-01
ES514365A0 (es) 1983-04-16
HU186342B (en) 1985-07-29
ES504682A0 (es) 1982-12-01
AR231273A1 (es) 1984-10-31
AR229188A1 (es) 1983-06-30
DD202286A5 (de) 1983-09-07
ZA815554B (en) 1982-08-25
DK358381A (da) 1982-02-14
AR231274A1 (es) 1984-10-31
ES8306473A1 (es) 1983-06-01
AR231631A1 (es) 1985-01-31

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19991007