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ES8305343A3 - Benzhydryl:piperazine derivs. and their salts - Google Patents

Benzhydryl:piperazine derivs. and their salts

Info

Publication number
ES8305343A3
ES8305343A3 ES514167A ES514167A ES8305343A3 ES 8305343 A3 ES8305343 A3 ES 8305343A3 ES 514167 A ES514167 A ES 514167A ES 514167 A ES514167 A ES 514167A ES 8305343 A3 ES8305343 A3 ES 8305343A3
Authority
ES
Spain
Prior art keywords
salts
benzhydryl
piperazine
formula
derivs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES514167A
Other languages
Spanish (es)
Other versions
ES514167A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ferrer Internacional SA
Original Assignee
Ferrer Internacional SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrer Internacional SA filed Critical Ferrer Internacional SA
Priority to ES514167A priority Critical patent/ES8305343A3/en
Publication of ES514167A0 publication Critical patent/ES514167A0/en
Publication of ES8305343A3 publication Critical patent/ES8305343A3/en
Expired legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Piperazine of formula (II) reacts with a halogenated cpd. (C6H5)2CHX, where X is Cl, Br or I, in an inert solvent contg. a base and at ambient temps. to give benzhydryl piperazines (formula (I)) and its salts with physiologically acceptable salts. R can be various radicals. The cpds. have application in treatment of cerebral circulation, coronary and periferal vascular disorders.
ES514167A 1982-07-20 1982-07-20 Benzhydryl:piperazine derivs. and their salts Expired ES8305343A3 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES514167A ES8305343A3 (en) 1982-07-20 1982-07-20 Benzhydryl:piperazine derivs. and their salts

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES514167A ES8305343A3 (en) 1982-07-20 1982-07-20 Benzhydryl:piperazine derivs. and their salts

Publications (2)

Publication Number Publication Date
ES514167A0 ES514167A0 (en) 1983-04-01
ES8305343A3 true ES8305343A3 (en) 1983-04-01

Family

ID=8484487

Family Applications (1)

Application Number Title Priority Date Filing Date
ES514167A Expired ES8305343A3 (en) 1982-07-20 1982-07-20 Benzhydryl:piperazine derivs. and their salts

Country Status (1)

Country Link
ES (1) ES8305343A3 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004089377A1 (en) * 2003-04-08 2004-10-21 Neuromed Technologies, Inc. Calcium channel blockers comprising two benzhydril moieties
US6943168B2 (en) 1998-06-30 2005-09-13 Neuromed Technologies Inc. Calcium channel inhibitors comprising benzhydril spaced from piperazine
US7186726B2 (en) 1998-06-30 2007-03-06 Neuromed Pharmaceuticals Ltd. Preferentially substituted calcium channel blockers

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6943168B2 (en) 1998-06-30 2005-09-13 Neuromed Technologies Inc. Calcium channel inhibitors comprising benzhydril spaced from piperazine
US6949554B2 (en) 1998-06-30 2005-09-27 Neuromed Technologies Inc. Calcium channel blockers comprising two benzhydril moieties
US6951862B2 (en) 1998-06-30 2005-10-04 Neuromed Technologies, Inc. Calcium channel blockers comprising two benzhydril moieties
US7064128B2 (en) 1998-06-30 2006-06-20 Neuromed Technologies, Inc. Preferentially substituted calcium channel blockers
US7186726B2 (en) 1998-06-30 2007-03-06 Neuromed Pharmaceuticals Ltd. Preferentially substituted calcium channel blockers
US7666865B2 (en) 1998-06-30 2010-02-23 Neuromed Pharmaceuticals Ltd. Calcium channel blockers
WO2004089377A1 (en) * 2003-04-08 2004-10-21 Neuromed Technologies, Inc. Calcium channel blockers comprising two benzhydril moieties

Also Published As

Publication number Publication date
ES514167A0 (en) 1983-04-01

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