ES8305343A3 - Benzhydryl:piperazine derivs. and their salts - Google Patents
Benzhydryl:piperazine derivs. and their saltsInfo
- Publication number
- ES8305343A3 ES8305343A3 ES514167A ES514167A ES8305343A3 ES 8305343 A3 ES8305343 A3 ES 8305343A3 ES 514167 A ES514167 A ES 514167A ES 514167 A ES514167 A ES 514167A ES 8305343 A3 ES8305343 A3 ES 8305343A3
- Authority
- ES
- Spain
- Prior art keywords
- salts
- benzhydryl
- piperazine
- formula
- derivs
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Piperazine of formula (II) reacts with a halogenated cpd. (C6H5)2CHX, where X is Cl, Br or I, in an inert solvent contg. a base and at ambient temps. to give benzhydryl piperazines (formula (I)) and its salts with physiologically acceptable salts. R can be various radicals. The cpds. have application in treatment of cerebral circulation, coronary and periferal vascular disorders.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES514167A ES8305343A3 (en) | 1982-07-20 | 1982-07-20 | Benzhydryl:piperazine derivs. and their salts |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES514167A ES8305343A3 (en) | 1982-07-20 | 1982-07-20 | Benzhydryl:piperazine derivs. and their salts |
Publications (2)
Publication Number | Publication Date |
---|---|
ES514167A0 ES514167A0 (en) | 1983-04-01 |
ES8305343A3 true ES8305343A3 (en) | 1983-04-01 |
Family
ID=8484487
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES514167A Expired ES8305343A3 (en) | 1982-07-20 | 1982-07-20 | Benzhydryl:piperazine derivs. and their salts |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES8305343A3 (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004089377A1 (en) * | 2003-04-08 | 2004-10-21 | Neuromed Technologies, Inc. | Calcium channel blockers comprising two benzhydril moieties |
US6943168B2 (en) | 1998-06-30 | 2005-09-13 | Neuromed Technologies Inc. | Calcium channel inhibitors comprising benzhydril spaced from piperazine |
US7186726B2 (en) | 1998-06-30 | 2007-03-06 | Neuromed Pharmaceuticals Ltd. | Preferentially substituted calcium channel blockers |
-
1982
- 1982-07-20 ES ES514167A patent/ES8305343A3/en not_active Expired
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6943168B2 (en) | 1998-06-30 | 2005-09-13 | Neuromed Technologies Inc. | Calcium channel inhibitors comprising benzhydril spaced from piperazine |
US6949554B2 (en) | 1998-06-30 | 2005-09-27 | Neuromed Technologies Inc. | Calcium channel blockers comprising two benzhydril moieties |
US6951862B2 (en) | 1998-06-30 | 2005-10-04 | Neuromed Technologies, Inc. | Calcium channel blockers comprising two benzhydril moieties |
US7064128B2 (en) | 1998-06-30 | 2006-06-20 | Neuromed Technologies, Inc. | Preferentially substituted calcium channel blockers |
US7186726B2 (en) | 1998-06-30 | 2007-03-06 | Neuromed Pharmaceuticals Ltd. | Preferentially substituted calcium channel blockers |
US7666865B2 (en) | 1998-06-30 | 2010-02-23 | Neuromed Pharmaceuticals Ltd. | Calcium channel blockers |
WO2004089377A1 (en) * | 2003-04-08 | 2004-10-21 | Neuromed Technologies, Inc. | Calcium channel blockers comprising two benzhydril moieties |
Also Published As
Publication number | Publication date |
---|---|
ES514167A0 (en) | 1983-04-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PH23617A (en) | Pump block for interfacing irradiation chamber to photoactivation patient treatment system | |
ATE90573T1 (en) | METHOD OF STABILIZING HUMAN ALBUMIN SOLUTIONS AND SOLUTION OBTAINED. | |
SE380435B (en) | BLOOD CIRCULATION ASSISTANCE INCLUDING A BALLOON PLACED IN A PATIENT'S SPECIES | |
EP0102534A3 (en) | Hair-growing agent | |
DE69106237D1 (en) | Anti-migraine alkoxypyrimidine derivatives. | |
EP0295280A4 (en) | Use of protoporphyrin and tin mesoporphyrin for the manufacture of a medicament for the treatment of psoriasis. | |
IL91423A0 (en) | Thrombus control agent | |
IL86862A0 (en) | Double-stranded rna correction of abnormalities in circulating immune complexes and monocyte function | |
ATE104151T1 (en) | TROMBOSE TREATMENT WITH FIBRINOLYTICS AND PROSTACYCLINES. | |
EP0185964A3 (en) | Dihydropyridine-carboxylic acid amides, process for their preparation and their use in medicaments | |
ES8305343A3 (en) | Benzhydryl:piperazine derivs. and their salts | |
DE69032000D1 (en) | Treatment of cardiac dysfunction with 15-keto-prostaglandin derivatives | |
ES2108497T3 (en) | COMPOUNDS OF 3-BENZOIL-3,7-DIAZABICICLO (3,3,1) NONANO WITH ANTIARRHYTHMIC ACTION. | |
ZA822158B (en) | ||
SE8201184L (en) | ASSOCIATION WITH ANTITUSIVE EFFECT | |
EP0454429A3 (en) | Use of 15-dehydroxy-16-oxoprostaglandin derivatives in the treatment of allergic diseases | |
DK277387A (en) | THERAPEUTIC TOPICAL COMPOSITION AGAINST A HYPERPROLIFIING EPITHAL DISEASE | |
ZA913920B (en) | Therapeutic compound | |
GR3017672T3 (en) | Therapeutic agent for diabetic gangrene. | |
EP0458536A3 (en) | Therapeutic agent for treatment and prevention of adult respiratory distress syndrome | |
ATE142498T1 (en) | THE USE OF 1-(5-OXOHEXYL)-3-METHYL-7-N-PROPYL-XANTHINE IN VASCULAR SURGERY | |
ATE135213T1 (en) | TREATMENT OF ANIMALS | |
UA11470A1 (en) | METHOD OF TREATMENT OF MALIGNANT TUMORS OF THE ABDOMINAL PERIOD | |
IT1218512B (en) | DISPOSABLE FACE DISPOSABLE APPARATUS IN MEDICAL PRACTICES |