ES8303452A1 - Procedure for the obtaining of acetilsalicilicos or salicillic esters in c-21 of hydroxylated steroids of the pregnanical series. (Machine-translation by Google Translate, not legally binding)
- Google Patents
Procedure for the obtaining of acetilsalicilicos or salicillic esters in c-21 of hydroxylated steroids of the pregnanical series. (Machine-translation by Google Translate, not legally binding)
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Laboratorios Menarini SA
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Laboratorios Menarini SA
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Priority to ES511296ApriorityCriticalpatent/ES8303452A1/en
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Publication of ES8303452A1publicationCriticalpatent/ES8303452A1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Steroid Compounds
(AREA)
Abstract
Procedure for the obtaining of acetilsalicilicos or salicillic esters in c-21 of hydroxylated steroids of the pregnanical series. It consists of the reaction of a compound of formula (I), in which r, r, ryr can be several types of radicals, with a reagent derivative of metasulphonic acid, in an approtic solvent of the etereo type, in the presence of an excess equimolar of pyridine, at a temperature comprised between 0 c and -5 c; following the reaction with a compound of formula (II), where r is hydrogen or acetile, at a temperature between 60 c and 120 c. These compounds have pharmacological applications for their anti-inflammatory activity. (Machine-translation by Google Translate, not legally binding)
ES511296A1982-04-071982-04-07Procedure for the obtaining of acetilsalicilicos or salicillic esters in c-21 of hydroxylated steroids of the pregnanical series. (Machine-translation by Google Translate, not legally binding)
ExpiredES8303452A1
(en)
Procedure for the obtaining of acetilsalicilicos or salicillic esters in c-21 of hydroxylated steroids of the pregnanical series. (Machine-translation by Google Translate, not legally binding)
Procedure for the obtaining of acetilsalicilicos or salicillic esters in c-21 of hydroxylated steroids of the pregnanical series. (Machine-translation by Google Translate, not legally binding)
Procedure for the obtaining of acetilsalicilicos or salicillic esters in c-21 of hydroxylated steroids of the pregnanical series. (Machine-translation by Google Translate, not legally binding)
Procedure for the obtaining of acetilsalicilicos or salicillic esters in c-21 of hydroxylated steroids of the pregnanical series. (Machine-translation by Google Translate, not legally binding)
Procedure for the preparation of salicic or acetilsalicile esters in c-21 of hydroxylated steroids of the pregnanic series. (Machine-translation by Google Translate, not legally binding)
Procedure for the preparation of 1,1-dioxides of 4-hidroxi-2H-1,2-benzotiazina-3-3-carboxamina. (Machine-translation by Google Translate, not legally binding)
Procedure for the obtaining of salicic or acetilisalicile esters in c-21 of hydroxylated steroids of the pregnanic series. (Machine-translation by Google Translate, not legally binding)