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ES8303086A1 - "un metodo para producir una forma de farmaco para administracion no parenteral a base de l-piroglutamil-l-histidil-l-prolinamida." - Google Patents

"un metodo para producir una forma de farmaco para administracion no parenteral a base de l-piroglutamil-l-histidil-l-prolinamida."

Info

Publication number
ES8303086A1
ES8303086A1 ES512149A ES512149A ES8303086A1 ES 8303086 A1 ES8303086 A1 ES 8303086A1 ES 512149 A ES512149 A ES 512149A ES 512149 A ES512149 A ES 512149A ES 8303086 A1 ES8303086 A1 ES 8303086A1
Authority
ES
Spain
Prior art keywords
analogue
pharmaceutical preparations
preparations containing
containing trh
trh
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES512149A
Other languages
English (en)
Other versions
ES512149A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of ES8303086A1 publication Critical patent/ES8303086A1/es
Publication of ES512149A0 publication Critical patent/ES512149A0/es
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401—Proline; Derivatives thereof, e.g. captopril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A61K38/066—TRH, thyroliberin, thyrotropin releasing hormone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE UNA FORMA DE FARMACO PARA ADMINISTRACION NO PARENTERAL A BASE DE L-PIROGLUTAMIL-L-HISTADIL-L-PROLINAMIDA. CONSISTE EN MEZCLAR L-PIROGLUTAMIL-L-HISTIDIL-L-PROLINAMIDA, SU SAL O UNO DE SUS ANALOGOS CAPAZ DE SER ABSORBIDO EN LA CORRIENTE SANGUINEA Y UN ACIDO HIDROXICARBOXILICO O POLICARBOXILICO C <- ; Y LLEVAR LA MEZCLA A UN PH COMPRENDIDO ENTRE 2 Y 6. ESTA PREPARACION TIENE APLICACIONES PARA ESTIMULAR LA LIBERACION DE HORMONA ESTIMULANTE DEL TIROIDES PROCEDENTE DE LA GLANDULA PITUITARIA Y POR ACTUAR SOBRE EL SISTEMA NERVIOSO CENTRAL.
ES512149A 1981-05-14 1982-05-13 "un metodo para producir una forma de farmaco para administracion no parenteral a base de l-piroglutamil-l-histidil-l-prolinamida." Granted ES512149A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56073293A JPS57188526A (en) 1981-05-14 1981-05-14 Peptide-containing pharmaceutical preparation

Publications (2)

Publication Number Publication Date
ES8303086A1 true ES8303086A1 (es) 1983-02-01
ES512149A0 ES512149A0 (es) 1983-02-01

Family

ID=13513959

Family Applications (1)

Application Number Title Priority Date Filing Date
ES512149A Granted ES512149A0 (es) 1981-05-14 1982-05-13 "un metodo para producir una forma de farmaco para administracion no parenteral a base de l-piroglutamil-l-histidil-l-prolinamida."

Country Status (9)

Country Link
US (1) US4504470A (es)
EP (1) EP0067513B1 (es)
JP (1) JPS57188526A (es)
KR (1) KR880001983B1 (es)
CA (1) CA1165245A (es)
DE (1) DE3276743D1 (es)
ES (1) ES512149A0 (es)
GR (1) GR75495B (es)
PT (1) PT74891B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5474980A (en) * 1984-10-04 1995-12-12 Monsanto Company Prolonged release of biologically active somatotropins
EP0177342A3 (en) * 1984-10-04 1987-12-02 Genentech, Inc. Oral formulation of therapeutic proteins
US5411951A (en) * 1984-10-04 1995-05-02 Monsanto Company Prolonged release of biologically active somatotropin
FR2585709B1 (fr) * 1985-08-05 1987-10-02 Adir Nouveaux derives peptidiques a structure lactonique ou cycloamidique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
JP2526589B2 (ja) * 1986-08-08 1996-08-21 武田薬品工業株式会社 ペプチド含有マイクロカプセルおよびその製造法
US4897256A (en) * 1986-11-25 1990-01-30 Abbott Laboratories LHRH analog formulations
AU618517B2 (en) * 1986-12-23 1992-01-02 Eugene J. Van Scott Additives enhancing topical actions of therapeutic agents
JPS63316724A (ja) * 1987-06-19 1988-12-26 Nippon Shinyaku Co Ltd 抗けいれん剤
DE3845000C2 (de) * 1987-07-10 1998-11-19 Novartis Ag Anwendung von Octreotid zur Behandlung von Brustkrebs
US5059587A (en) * 1987-08-03 1991-10-22 Toyo Jozo Company, Ltd. Physiologically active peptide composition for nasal administration
JPH02104531A (ja) * 1988-10-14 1990-04-17 Toyo Jozo Co Ltd 経鼻投与用生理活性ペプチド組成物
EP0432431B1 (en) * 1989-11-16 1993-06-16 PHIDEA S.p.A. Liquid pharmaceutical composition for nasal administration containing a polypeptide as active ingredient
US5270042A (en) * 1993-02-23 1993-12-14 Juanita Whitham Medicinal salve composition
US5424289A (en) * 1993-07-30 1995-06-13 Alza Corporation Solid formulations of therapeutic proteins for gastrointestinal delivery
DE69430132T2 (de) * 1993-10-21 2002-08-29 Hisamitsu Pharmaceutical Co., Inc. Pernasale zusammensetzung und diese enthaltende pernasale zubereitung
CA2245145A1 (en) * 1996-02-05 1997-08-07 Eli Lilly And Company Method of treating beta-amyloid peptide associated conditions using trh
AU2002314847A1 (en) 2001-05-31 2002-12-09 Upsher-Smith Laboratories, Inc. Dermatological compositions and methods comprising alpha-hydroxy acids or derivatives
US20030159702A1 (en) * 2002-01-21 2003-08-28 Lindell Katarina E.A. Formulation and use manufacture thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS528375B2 (es) * 1973-07-02 1977-03-09
JPS51118841A (en) * 1975-04-03 1976-10-19 Takeda Chem Ind Ltd A drug for improving and treating clouding of consciousness
DE2558858A1 (de) * 1975-12-27 1977-07-14 Hoechst Ag Klebstoffgemisch
US4211769A (en) * 1977-08-24 1980-07-08 Takeda Chemical Industries, Ltd. Preparations for vaginal administration
US4181709A (en) * 1977-09-02 1980-01-01 Eastman Kodak Company Rumen-stable pellets
GB2042888B (en) * 1979-03-05 1983-09-28 Teijin Ltd Preparation for administration to the mucosa of the oral or nasal cavity
JPS605570B2 (ja) * 1979-10-06 1985-02-12 株式会社ジャ−ド 崩壊剤の製造法
NZ196349A (en) * 1980-03-07 1984-08-24 Interx Research Corp Enhancement of absorption rate of orally administered polar bioactive agents
JPS56138110A (en) * 1980-03-28 1981-10-28 Teijin Ltd Suppository containing citric acid or salt thereof

Also Published As

Publication number Publication date
KR830009771A (ko) 1983-12-23
CA1165245A (en) 1984-04-10
EP0067513B1 (en) 1987-07-15
EP0067513A2 (en) 1982-12-22
ES512149A0 (es) 1983-02-01
GR75495B (es) 1984-07-24
PT74891B (en) 1983-12-23
US4504470A (en) 1985-03-12
JPH0222049B2 (es) 1990-05-17
DE3276743D1 (en) 1987-08-20
JPS57188526A (en) 1982-11-19
EP0067513A3 (en) 1983-10-05
PT74891A (en) 1982-06-01
KR880001983B1 (ko) 1988-10-10

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19960603