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ES8301486A1 - Nuevos derivados 1-n-(x-hidroxi-w-aminoalcanoil)de 5,3'4'- tridesoxi-o 5,3,4'-tridesoxi-6'-n-metil-o 5,3',4',6 -tetra- desoxi-kanamicina b y produccion de los mismos - Google Patents

Nuevos derivados 1-n-(x-hidroxi-w-aminoalcanoil)de 5,3'4'- tridesoxi-o 5,3,4'-tridesoxi-6'-n-metil-o 5,3',4',6 -tetra- desoxi-kanamicina b y produccion de los mismos

Info

Publication number
ES8301486A1
ES8301486A1 ES504697A ES504697A ES8301486A1 ES 8301486 A1 ES8301486 A1 ES 8301486A1 ES 504697 A ES504697 A ES 504697A ES 504697 A ES504697 A ES 504697A ES 8301486 A1 ES8301486 A1 ES 8301486A1
Authority
ES
Spain
Prior art keywords
aminoalkanoyl
omega
deoxykanamycin
compounds
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES504697A
Other languages
English (en)
Other versions
ES504697A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP55109854A external-priority patent/JPS5753496A/ja
Priority claimed from JP56058389A external-priority patent/JPS57175198A/ja
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Publication of ES8301486A1 publication Critical patent/ES8301486A1/es
Publication of ES504697A0 publication Critical patent/ES504697A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE 1-N-(<007>-HIDROXI-W-AMINOALCANOIL)-5,3'',4''-TRIDESOXIKANAMICINA B O DE 1-N-(<007>-HIDROXI-W-AMINOALCANOIL)-5,3'',4'',6''''TETRADESOXIKANAMICINA B, DE FORMULA (I), EN LA QUE R ES HIDROGENO O HIDROXILO; Y R ES EL GRUPO <024>CO<024>CHOH<024>(CH W)<009>NH , DONDE N VALE DE 1 A 3. CONSISTE EN LA REACCION DE ACILACION DEL GRUPO 1-AMINO DE UN COMPUESTO DE FORMULA (I), EN LA QUE R ES HIDROGENO Y R TIENE EL SIGNIFICADO ANTERIOR, O UN DERIVADO AMINO-PROTEGIDO EN TODOS LOS DEMAS GRUPOS AMINO, POR TRATAMIENTO CON UN ACIDO <007>-HIDROXI-W-AMINOALCANOICO O UN DERIVADO AMINO PROTEGIDO DEL MISMO, DE FORMULA (II), EN LA QUE A ES HIDROGENO Y B UN GRUPO PROTECTOR O AMBOS JUNTOS FORMAN UN GRUPO PROTECTOR. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO ANTIBIOTICOS.
ES504697A 1980-08-12 1981-08-11 Nuevos derivados 1-n-(x-hidroxi-w-aminoalcanoil)de 5,3'4'- tridesoxi-o 5,3,4'-tridesoxi-6'-n-metil-o 5,3',4',6 -tetra- desoxi-kanamicina b y produccion de los mismos Granted ES504697A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP55109854A JPS5753496A (en) 1980-08-12 1980-08-12 1-n-acyl derivative of 5,3',4'-trideoxykanamycin b or 5,3',4',6'- tetradeoxykanamycin b, and their preparation
JP56058389A JPS57175198A (en) 1981-04-20 1981-04-20 1-n-acyl derivative of 5,3,4-trideoxy-6-n-methylkanamycin b and their preparation

Publications (2)

Publication Number Publication Date
ES8301486A1 true ES8301486A1 (es) 1982-12-01
ES504697A0 ES504697A0 (es) 1982-12-01

Family

ID=26399440

Family Applications (4)

Application Number Title Priority Date Filing Date
ES504697A Granted ES504697A0 (es) 1980-08-12 1981-08-11 Nuevos derivados 1-n-(x-hidroxi-w-aminoalcanoil)de 5,3'4'- tridesoxi-o 5,3,4'-tridesoxi-6'-n-metil-o 5,3',4',6 -tetra- desoxi-kanamicina b y produccion de los mismos
ES514622A Expired ES8308334A1 (es) 1980-08-12 1982-07-31 "proceso para la produccion de 5,3',4'-tridesoxi-6'-n-metilkanamicina b".
ES514621A Granted ES514621A0 (es) 1980-08-12 1982-07-31 "proceso para la produccion de 5,3',4',6"-tetradesoxikanamicina b".
ES514620A Expired ES8401092A1 (es) 1980-08-12 1982-07-31 "proceso para la produccion de una 1-n-(-hidroxi-aminoalcanoil)-5,3',4'-tridesoxi-6'-n-metilkanamicina b".

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES514622A Expired ES8308334A1 (es) 1980-08-12 1982-07-31 "proceso para la produccion de 5,3',4'-tridesoxi-6'-n-metilkanamicina b".
ES514621A Granted ES514621A0 (es) 1980-08-12 1982-07-31 "proceso para la produccion de 5,3',4',6"-tetradesoxikanamicina b".
ES514620A Expired ES8401092A1 (es) 1980-08-12 1982-07-31 "proceso para la produccion de una 1-n-(-hidroxi-aminoalcanoil)-5,3',4'-tridesoxi-6'-n-metilkanamicina b".

Country Status (9)

Country Link
KR (1) KR850000979B1 (es)
CA (1) CA1175816A (es)
CH (1) CH648564A5 (es)
DE (1) DE3131731C2 (es)
ES (4) ES504697A0 (es)
FR (1) FR2491073A1 (es)
GB (1) GB2082575B (es)
IT (1) IT1167959B (es)
NL (1) NL8103639A (es)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS554118B2 (es) * 1973-08-29 1980-01-29

Also Published As

Publication number Publication date
ES514620A0 (es) 1983-12-16
KR830006325A (ko) 1983-09-24
ES514622A0 (es) 1983-08-16
FR2491073A1 (fr) 1982-04-02
DE3131731C2 (de) 1984-02-16
ES8401092A1 (es) 1983-12-16
CH648564A5 (de) 1985-03-29
FR2491073B1 (es) 1984-08-03
NL8103639A (nl) 1982-03-01
DE3131731A1 (de) 1982-03-11
ES8308334A1 (es) 1983-08-16
IT1167959B (it) 1987-05-20
GB2082575A (en) 1982-03-10
CA1175816A (en) 1984-10-09
ES8401093A1 (es) 1983-12-16
IT8109493A0 (it) 1981-08-07
GB2082575B (en) 1984-04-18
KR850000979B1 (ko) 1985-07-05
ES514621A0 (es) 1983-12-16
ES504697A0 (es) 1982-12-01

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