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ES8206441A1 - 3-Hydroxy-3-phenyl-2-propylamine derivatives - Google Patents

3-Hydroxy-3-phenyl-2-propylamine derivatives

Info

Publication number
ES8206441A1
ES8206441A1 ES507158A ES507158A ES8206441A1 ES 8206441 A1 ES8206441 A1 ES 8206441A1 ES 507158 A ES507158 A ES 507158A ES 507158 A ES507158 A ES 507158A ES 8206441 A1 ES8206441 A1 ES 8206441A1
Authority
ES
Spain
Prior art keywords
image
hydroxy
phenyl
formula
alkyl group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES507158A
Other languages
Spanish (es)
Other versions
ES507158A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Evonik Operations GmbH
Original Assignee
Degussa GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa GmbH filed Critical Degussa GmbH
Publication of ES507158A0 publication Critical patent/ES507158A0/en
Publication of ES8206441A1 publication Critical patent/ES8206441A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C27/00—Processes involving the simultaneous production of more than one class of oxygen-containing compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Compounds of the formula:- < IMAGE > in which X represents the group < IMAGE > or < IMAGE > R2 represents hydrogen or a C1-C6-alkyl group and R3 represents hydrogen or a hydroxy group whilst R1 represents the adamantyl radical or a saturated or monounsaturated C3-C16-cycloalkyl radical which may be substituted by a C1-C4-alkyl group or by a halogen atom, and their acid addition salts are prepared by reacting corresponding N,N'-methylene- bis-oxazolidines with ketones of the formula R1-CO-C(R2)H2 in acid medium, optionally followed by reduction.
ES507158A 1980-11-17 1981-11-16 3-Hydroxy-3-phenyl-2-propylamine derivatives Expired ES8206441A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3043350 1980-11-17

Publications (2)

Publication Number Publication Date
ES507158A0 ES507158A0 (en) 1982-08-16
ES8206441A1 true ES8206441A1 (en) 1982-08-16

Family

ID=6116998

Family Applications (1)

Application Number Title Priority Date Filing Date
ES507158A Expired ES8206441A1 (en) 1980-11-17 1981-11-16 3-Hydroxy-3-phenyl-2-propylamine derivatives

Country Status (17)

Country Link
AT (1) AT379379B (en)
CA (1) CA1187489A (en)
CS (1) CS227018B2 (en)
DD (1) DD202285A5 (en)
DK (1) DK507581A (en)
EG (1) EG15343A (en)
ES (1) ES8206441A1 (en)
FI (1) FI77649C (en)
GB (1) GB2087397A (en)
GR (1) GR76339B (en)
HU (1) HU185671B (en)
IE (1) IE52081B1 (en)
LU (1) LU83751A1 (en)
MX (1) MX7032E (en)
NO (1) NO152294C (en)
PT (1) PT73979B (en)
YU (1) YU42253B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0211254A3 (en) * 1985-07-31 1988-05-04 ASTA Pharma Aktiengesellschaft Cycloaliphatic ketoamines

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI70205C (en) * 1978-05-17 1986-09-15 Degussa FOERFARANDE FOER FRAMSTAELLNING AV NYA TERAPEUTISKT ANVAENDBARA L- / 3-HYDROXI-3-PHENYLPROPYL- (2) / - / 3-OXO-PROPYL / AMINER

Also Published As

Publication number Publication date
PT73979A (en) 1981-12-01
PT73979B (en) 1983-04-26
GR76339B (en) 1984-08-04
NO152294C (en) 1985-09-04
CA1187489A (en) 1985-05-21
FI77649C (en) 1989-04-10
GB2087397A (en) 1982-05-26
NO152294B (en) 1985-05-28
HU185671B (en) 1985-03-28
LU83751A1 (en) 1982-02-18
IE52081B1 (en) 1987-06-10
ES507158A0 (en) 1982-08-16
DK507581A (en) 1982-05-18
CS227018B2 (en) 1984-04-16
FI813623L (en) 1982-05-18
IE812677L (en) 1982-05-17
NO813881L (en) 1982-05-18
YU269081A (en) 1983-09-30
ATA493281A (en) 1985-05-15
DD202285A5 (en) 1983-09-07
EG15343A (en) 1986-09-30
MX7032E (en) 1987-03-03
YU42253B (en) 1988-06-30
FI77649B (en) 1988-12-30
AT379379B (en) 1985-12-27

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