ES8200228A1 - Metodo para producir preparados medicinales para el trata- miento de carcinomas - Google Patents
Metodo para producir preparados medicinales para el trata- miento de carcinomasInfo
- Publication number
- ES8200228A1 ES8200228A1 ES491356A ES491356A ES8200228A1 ES 8200228 A1 ES8200228 A1 ES 8200228A1 ES 491356 A ES491356 A ES 491356A ES 491356 A ES491356 A ES 491356A ES 8200228 A1 ES8200228 A1 ES 8200228A1
- Authority
- ES
- Spain
- Prior art keywords
- carcinoma
- preparing
- treatment
- medicinal preparation
- agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 201000009030 Carcinoma Diseases 0.000 title abstract 3
- 238000002360 preparation method Methods 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 238000005406 washing Methods 0.000 abstract 2
- 238000004113 cell culture Methods 0.000 abstract 1
- 239000000824 cytostatic agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/13—Tumour cells, irrespective of tissue of origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Developmental Biology & Embryology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
METODO PARA PRODUCIR PREPARADOS MEDICINALES PARA EL TRATAMIENTO DE CARCINOMAS. COMO MATERIAL DE PARTIDA SE UTILIZAN CELULAS DE CARCINOMA QUE SE PUEDEN RECUPERAR DE UNA MANERA CONVENCIONAL, CULTIVANDOSE E INCUBANDOSE DICHAS CELULAS EN UN MEDIO DE CRECIMIENTO NUTRICIO. SE SOMETE A UNA PLURALIDAD DE PORCIONES DETERMINADAS DE DICHO CULTIVO A LA ACCION DE UNA PLURALIDAD DE AGENTES CITOSTATICOS, SELECCIONANDOSE EL AGENTE QUE PRESENTA UN DETERIORO MORFOLOGICO VISIBLE. LA PORCION RESTANTE DEL CULTIVO SE TRATA CON DICHO AGENTE, INCUBANDOSE PREFERENTEMENTE DURANTE UN PERIODO DE SEIS A DOCE HORAS, A UNA TEMPERATURA DE, APROXIMADAMENTE, 37 C, DE TAL MANERA QUE, APROXIMADAMENTE, UN 30 A 70 POR 100 DE DICHAS CELULAS PERMANEZCAN INTACTAS BAJO EXAMEN MICROSCOPICO Y PARCIALMENTE DEBILITADAS. ESTAS CELULAS DEBILITADAS SE LAVAN CON UNA SOLUCION FISIOLOGICAMENTE ACEPTABLE PARA ELIMINAR EL AGENTE CITOSTATICO. LAS CELULAS QUE HAN SIDO DEBILITADAS EN EL GRADO DESEADO SON CENTRIFUGADAS A, APROXIMADAMENTE, 800 HASTA 1.000 RPM DURANTE DIEZ MINUTOS Y SUSPENDIDAS PREFERIBLEMENTE EN UN FLUIDO FISIOLOGICAMENTE ACEPTABLE. LA CONCENTRACION DE LAS CELULAS EN LOS PREPARADOS FARMACEUTICOS RESULTANTES, PUESTOS PARA ADMINISTRACION TRAS DILUCION, ES PREFERIBLEMENTE DE ALREDEDOR DE 10 CELULAS POR MILILITRO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19792918927 DE2918927A1 (de) | 1979-05-10 | 1979-05-10 | Arzneipraeparat zur behandlung von carcinomen und verfahren zu dessen herstellung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES491356A0 ES491356A0 (es) | 1981-11-16 |
| ES8200228A1 true ES8200228A1 (es) | 1981-11-16 |
Family
ID=6070441
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES491356A Expired ES8200228A1 (es) | 1979-05-10 | 1980-05-09 | Metodo para producir preparados medicinales para el trata- miento de carcinomas |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0019167B1 (es) |
| JP (1) | JPS55151515A (es) |
| AT (1) | AT369653B (es) |
| AU (1) | AU5806980A (es) |
| CA (1) | CA1139219A (es) |
| CH (1) | CH647152A5 (es) |
| DD (1) | DD150545A5 (es) |
| DE (2) | DE2918927A1 (es) |
| DK (1) | DK189580A (es) |
| ES (1) | ES8200228A1 (es) |
| FI (1) | FI801420A (es) |
| FR (1) | FR2455891A1 (es) |
| GB (1) | GB2048069B (es) |
| GR (1) | GR68513B (es) |
| IL (1) | IL59833A0 (es) |
| IT (1) | IT1133086B (es) |
| NO (1) | NO801388L (es) |
| PL (1) | PL224116A1 (es) |
| PT (1) | PT71195B (es) |
| ZA (1) | ZA802391B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3432714A1 (de) * | 1984-09-06 | 1986-04-24 | Behringwerke Ag, 3550 Marburg | Tumortherapeutikum und verfahren zu seiner herstellung |
| DE3806565A1 (de) * | 1988-03-01 | 1989-09-14 | Deutsches Krebsforsch | Virusmodifizierte tumorvakzinen fuer die immuntherapie von tumormetastasen |
| WO1992010198A1 (en) * | 1990-12-06 | 1992-06-25 | Johnson & Johnson Research Pty Limited | Immunotherapeutic agents, compositions and methods |
| SE9604581D0 (sv) * | 1996-12-12 | 1996-12-12 | Karolinska Innovations Ab | An agent against cancer and virus infections |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2024458A1 (en) * | 1970-05-20 | 1971-12-02 | Hartmann geb. Ungewitter, Philippine, Dr., 8000 München | Tumour antigen - modified and potentiated by irradiation |
| DE2643215A1 (de) * | 1976-09-25 | 1978-04-06 | Bayer Ag | Cancerostatisch wirksame praeparationen aus tumorzellen und ein verfahren zu ihrer herstellung |
| DE2802277A1 (de) * | 1978-01-19 | 1979-08-02 | Jaeger Karl Heinz Dr Med | Verfahren zur herstellung eines gegen boesartiges wachstum gerichteten immunologischen wirkstoffkomplexes aus zellen |
-
1979
- 1979-05-10 DE DE19792918927 patent/DE2918927A1/de not_active Withdrawn
-
1980
- 1980-04-15 GB GB8012348A patent/GB2048069B/en not_active Expired
- 1980-04-15 IL IL59833A patent/IL59833A0/xx unknown
- 1980-04-21 ZA ZA00802391A patent/ZA802391B/xx unknown
- 1980-04-28 CA CA000350795A patent/CA1139219A/en not_active Expired
- 1980-04-30 DK DK189580A patent/DK189580A/da unknown
- 1980-05-02 GR GR61842A patent/GR68513B/el unknown
- 1980-05-02 DE DE8080102400T patent/DE3065252D1/de not_active Expired
- 1980-05-02 FI FI801420A patent/FI801420A/fi not_active Application Discontinuation
- 1980-05-02 EP EP80102400A patent/EP0019167B1/de not_active Expired
- 1980-05-05 AU AU58069/80A patent/AU5806980A/en not_active Abandoned
- 1980-05-06 AT AT0240280A patent/AT369653B/de not_active IP Right Cessation
- 1980-05-06 CH CH3510/80A patent/CH647152A5/de not_active IP Right Cessation
- 1980-05-07 PT PT71195A patent/PT71195B/pt unknown
- 1980-05-08 PL PL22411680A patent/PL224116A1/xx unknown
- 1980-05-09 IT IT67731/80A patent/IT1133086B/it active
- 1980-05-09 JP JP6082680A patent/JPS55151515A/ja active Pending
- 1980-05-09 NO NO801388A patent/NO801388L/no unknown
- 1980-05-09 ES ES491356A patent/ES8200228A1/es not_active Expired
- 1980-05-09 FR FR8010400A patent/FR2455891A1/fr active Granted
- 1980-05-09 DD DD80221015A patent/DD150545A5/de unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT71195A (en) | 1980-06-01 |
| DE3065252D1 (en) | 1983-11-17 |
| EP0019167A3 (en) | 1981-09-09 |
| NO801388L (no) | 1980-11-11 |
| AT369653B (de) | 1983-01-25 |
| FR2455891A1 (fr) | 1980-12-05 |
| GR68513B (es) | 1982-01-11 |
| CH647152A5 (de) | 1985-01-15 |
| PL224116A1 (es) | 1981-07-10 |
| DK189580A (da) | 1980-11-11 |
| ZA802391B (en) | 1981-04-29 |
| CA1139219A (en) | 1983-01-11 |
| EP0019167B1 (de) | 1983-10-12 |
| EP0019167A2 (de) | 1980-11-26 |
| IL59833A0 (en) | 1980-06-30 |
| ES491356A0 (es) | 1981-11-16 |
| IT8067731A0 (it) | 1980-05-09 |
| DD150545A5 (de) | 1981-09-09 |
| FR2455891B1 (es) | 1983-12-30 |
| FI801420A (fi) | 1980-11-11 |
| GB2048069B (en) | 1983-05-25 |
| AU5806980A (en) | 1980-11-13 |
| IT1133086B (it) | 1986-07-09 |
| ATA240280A (de) | 1982-06-15 |
| JPS55151515A (en) | 1980-11-26 |
| DE2918927A1 (de) | 1980-11-20 |
| PT71195B (en) | 1981-09-17 |
| GB2048069A (en) | 1980-12-10 |
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